trihomomethionine (BioDeep_00000011606)

natural product

(2S)-2-amino-7-(methylsulfanyl)heptanoic acid

分子结构信息

SMILES: CSCCCCCC(C(=O)O)N
InChI: InChI=1S/C8H17NO2S/c1-12-6-4-2-3-5-7(9)8(10)11/h7H,2-6,9H2,1H3,(H,10,11)

A sulfur-containing amino acid consisting of 2-aminoheptanoic acid having a methylthio substituent at the 7-position.

3 个代谢物同义名

13 个数据库交叉引用编号

3 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(2)

aliphatic glucosinolate biosynthesis, side chain elongation cycle: 7-(methylthio)-2-oxoheptanoate + a proteinogenic amino acid ⟶ L-trihomomethionine + a 2-oxo carboxylate
glucosinolate biosynthesis from trihomomethionine: L-trihomomethionine + O₂ + a reduced [NADPH-hemoprotein reductase] ⟶ (E)-6-(methylthio)hexanaldoxime + CO₂ + H₂O + an oxidized [NADPH-hemoprotein reductase]

WikiPathways(1)

Glucosinolate biosynthesis from methionine: 5-Methylthiopentyl glucosinolate ⟶ 5-(Methylsulfinyl)pentyl glucosinolate

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

8 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

M E Schranz, A J Manzaneda, A J Windsor, M J Clauss, T Mitchell-Olds. Ecological genomics of Boechera stricta: identification of a QTL controlling the allocation of methionine- vs branched-chain amino acid-derived glucosinolates and levels of insect herbivory. Heredity. 2009 May; 102(5):465-74. doi: 10.1038/hdy.2009.12. [PMID: 19240753]
Daniel J Kliebenstein. A role for gene duplication and natural variation of gene expression in the evolution of metabolism. PloS one. 2008 Mar; 3(3):e1838. doi: 10.1371/journal.pone.0001838. [PMID: 18350173]
C H Hansen, U Wittstock, C E Olsen, A J Hick, J A Pickett, B A Halkier. Cytochrome p450 CYP79F1 from arabidopsis catalyzes the conversion of dihomomethionine and trihomomethionine to the corresponding aldoximes in the biosynthesis of aliphatic glucosinolates. The Journal of biological chemistry. 2001 Apr; 276(14):11078-85. doi: 10.1074/jbc.m010123200. [PMID: 11133994]