Penicillin-2 (BioDeep_00001104967)
代谢物信息卡片
Penicillin-2
化学式: C16H17KN2O4S (372.0546062000001)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1(C(N2C(S1)C(C2=O)N=C(CC3=CC=CC=C3)[O-])C(=O)O)C.[K+]
InChI: /q
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Samia Aleem, LaShawndra S Walker, Chi D Hornik, Michael J Smith, Chad A Grotegut, Kristin E D Weimer. Severe Congenital Syphilis in the Neonatal Intensive Care Unit: A Retrospective Case Series.
The Pediatric infectious disease journal.
2022 04; 41(4):335-339. doi:
10.1097/inf.0000000000003370. [PMID: 34620796] - Sophie J Jansen, Enrico Lopriore, Robbert G M Bredius, Martha T van der Beek, Dirk J A R Moes, Vincent Bekker. Benzylpenicillin Serum Concentrations in Neonates With Group B Streptococci Sepsis or Meningitis: A Descriptive Cohort Study.
The Pediatric infectious disease journal.
2021 05; 40(5):434-439. doi:
10.1097/inf.0000000000002993. [PMID: 33181784] - Shengzhi Yang, Yan Huang, Caiwu Li, Lei Jin, Wenwen Deng, Siyue Zhao, Daifu Wu, Yongguo He, Bei Li, Zhongliang Yu, Ti Li, Zhizhong Zhang, Xin Pan, Hemin Zhang, Likou Zou. The Fecal and Serum Metabolomics of Giant Pandas Based on Untargeted Metabolomics.
Zoological science.
2021 Apr; 38(2):179-186. doi:
10.2108/zs200106. [PMID: 33812357] - Georges Azar, Benjamin Wolff, Stéphane Azam, Martine Mauget-Faÿsse. Acute syphilitic posterior placoid chorioretinopathy presenting as atypical multiple evanescent white dot syndrome.
European journal of ophthalmology.
2021 Mar; 31(2):NP141-NP144. doi:
10.1177/1120672120957589. [PMID: 32878455] - Tanya Duke-Novakovski, Carolina Palacios Jimenez, Masako Fujiyama, Shannon G Beazley. Plasma histamine concentrations in horses administered sodium penicillin, guaifenesin-xylazine-ketamine and isoflurane with morphine or butorphanol.
Veterinary anaesthesia and analgesia.
2021 Jan; 48(1):17-25. doi:
10.1016/j.vaa.2020.10.003. [PMID: 33229232] - Michael A Van Es, Ruben P A Van Eijk, Tommy M Bunte, Leonard H Van Den Berg. A placebo-controlled trial to investigate the safety and efficacy of Penicillin G/Hydrocortisone in patients with ALS (PHALS trial).
Amyotrophic lateral sclerosis & frontotemporal degeneration.
2020 11; 21(7-8):584-592. doi:
10.1080/21678421.2020.1788093. [PMID: 32627599] - Edurne Peña-Mendizabal, Sergi Morais, Ángel Maquieira. Boosting the sensitivity of in vitroβ-lactam allergy diagnostic tests.
Chemical communications (Cambridge, England).
2020 Oct; 56(80):11973-11976. doi:
10.1039/d0cc04903d. [PMID: 33033809] - Hannah Cook, Mark Gompels. The wrong Spirochaete? Acute kidney injury in a returning traveller with syphilis - a case report.
BMC infectious diseases.
2020 Sep; 20(1):692. doi:
10.1186/s12879-020-05418-4. [PMID: 32957955] - Isabelle M D Gonzaga, Angela Moratalla, Katlin I B Eguiluz, Giancarlo R Salazar-Banda, Pablo Cañizares, Manuel A Rodrigo, Cristina Saez. Influence of the doping level of boron-doped diamond anodes on the removal of penicillin G from urine matrixes.
The Science of the total environment.
2020 Sep; 736(?):139536. doi:
10.1016/j.scitotenv.2020.139536. [PMID: 32485374] - Marie Sjölund, Carl Ekstrand, Per Wallgren, Ulf Bondesson, Märit Pringle, Björn Bengtsson. Exposure to benzylpenicillin after different dosage regimens in growing pigs.
Acta veterinaria Scandinavica.
2020 Sep; 62(1):55. doi:
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Scientific reports.
2020 08; 10(1):14160. doi:
10.1038/s41598-020-71083-x. [PMID: 32843685] - Shelia B Dunaway, Clare L Maxwell, Lauren C Tantalo, Sharon K Sahi, Christina M Marra. Neurosyphilis Treatment Outcomes After Intravenous Penicillin G Versus Intramuscular Procaine Penicillin Plus Oral Probenecid.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
2020 07; 71(2):267-273. doi:
10.1093/cid/ciz795. [PMID: 31504293] - Duygu D Corum, Orhan Corum, Orkun Atik, Hatice E Faki, Feray Altan, Kamil Uney. Effect of benzylpenicillin on intravenous pharmacokinetics of acyclovir in red-eared slider turtles (Trachemys scripta elegans).
Journal of veterinary pharmacology and therapeutics.
2020 Jul; 43(4):319-324. doi:
10.1111/jvp.12860. [PMID: 32212341] - Seiji Yoshimura, Roman V Koziy, Ryan Dickinson, Igor Moshynskyy, Joscelyn A McKenzie, Elemir Simko, José L Bracamonte. Use of serum amyloid A in serum and synovial fluid to detect eradication of infection in experimental septic arthritis in horses.
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire.
2020 Jul; 84(3):198-204. doi:
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BMJ case reports.
2020 Feb; 13(2):. doi:
10.1136/bcr-2019-232615. [PMID: 32029514] - Beichen Ding, Guoliang Sun, Shiliang Liu, Ejun Peng, Meimei Wan, Liang Chen, John Jackson, Anthony Atala. Three-Dimensional Renal Organoids from Whole Kidney Cells: Generation, Optimization, and Potential Application in Nephrotoxicology In Vitro.
Cell transplantation.
2020 Jan; 29(?):963689719897066. doi:
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Food chemistry.
2019 Aug; 288(?):39-46. doi:
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European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology.
2019 Aug; 38(8):1449-1455. doi:
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Journal of veterinary pharmacology and therapeutics.
2019 Jul; 42(4):461-475. doi:
10.1111/jvp.12766. [PMID: 31012501] - Styliani Tsiami, Andrea Regel, Xenofon Baraliakos, Jürgen Braun, Uta Kiltz. [Multi-Faceted Symptoms with Joint Pain, Exanthema and Eye Involvement].
Deutsche medizinische Wochenschrift (1946).
2019 06; 144(11):759-763. doi:
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Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
2019 05; 49(5):636-643. doi:
10.1111/cea.13338. [PMID: 30657219] - Bart G J Dekkers, Wouter F W Bierman, Daan J Touw, Jan-Willem C Alffenaar. Relevance of the drug-drug interactions between lidocaine and the pharmacokinetic enhancers ritonavir and cobicistat.
AIDS (London, England).
2019 05; 33(6):1100-1102. doi:
10.1097/qad.0000000000002162. [PMID: 30946167] - Karine Beiruti, Anan Abu Awad, Galina Keigler, Chen Hanna Ryder, Radi Shahien. Atypical development of neurosyphilis mimicking limbic encephalitis.
International journal of STD & AIDS.
2019 02; 30(2):194-197. doi:
10.1177/0956462418797873. [PMID: 30253732] - Vesa Cheng, Matthew Rawlins, Tim Chang, Emma Fox, John Dyer, Chris Allen, Edward Litton, Michael M Page, Kirsten Hoad, Jason A Roberts. Pharmacokinetics of Benzylpenicillin (Penicillin G) during Prolonged Intermittent Renal Replacement Therapy.
Chemotherapy.
2019; 64(1):17-21. doi:
10.1159/000499375. [PMID: 31167190] - Xiaofen Zhao, Yangfang Li, Kun Du, Yuqin Wu, Ling Liu, Shan Cui, Yan Zhang, Jin Gao, Richard F Keep, Jianming Xiang. Involvement of human and canine MRP1 and MRP4 in benzylpenicillin transport.
PloS one.
2019; 14(11):e0225702. doi:
10.1371/journal.pone.0225702. [PMID: 31774876] - Elke Abbeloos, Satu Pyörälä, Päivi Rajala-Schultz, Vesa Myllys. Determination of the intramammary dose of benzylpenicillin required to maintain an adequate concentration in the milk to inhibit Gram-positive bacteria in the clinically normal udder for 24 hr.
Journal of veterinary pharmacology and therapeutics.
2018 Oct; 41(5):691-698. doi:
10.1111/jvp.12671. [PMID: 29889313] - Shoko Ito, Masahiro Ashizawa, Ryo Sasaki, Takashi Ikeda, Yumiko Toda, Kiyomi Mashima, Kento Umino, Daisuke Minakata, Hirofumi Nakano, Ryoko Yamasaki, Yasufumi Kawasaki, Miyuki Sugimoto, Chihiro Yamamoto, Shin-Ichiro Fujiwara, Kaoru Hatano, Kazuya Sato, Iekuni Oh, Ken Ohmine, Kazuo Muroi, Jun Suzuki, Shuji Hatakeyama, Yuji Morisawa, Toshiyuki Yamada, Yoshinobu Kanda. False-positive elevation of 1,3-beta-D-glucan caused by continuous administration of penicillin G.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.
2018 Oct; 24(10):812-814. doi:
10.1016/j.jiac.2018.06.008. [PMID: 30006248] - Margarita N German, Kristina A Matkowskyj, Robert J Hoffman, Parul D Agarwal. A case of syphilitic hepatitis in an HIV-infected patient.
Human pathology.
2018 09; 79(?):184-187. doi:
10.1016/j.humpath.2018.02.017. [PMID: 29505766] - Shuhei Ikeda, Yusuke Yakushiji, Makoto Eriguchi, Yuka Fujii, Koji Ishitsuka, Hideo Hara. [Neurosyphilis with cerebellar ataxia, personality change and cognitive decline one year after onset of cerebral infarction].
Rinsho shinkeigaku = Clinical neurology.
2018 Aug; 58(8):499-504. doi:
10.5692/clinicalneurol.cn-001170. [PMID: 30068812] - M E Azoury, L Filì, R Bechara, N Scornet, L de Chaisemartin, R J Weaver, N Claude, B Maillere, P Parronchi, D Joseph, M Pallardy. Identification of T-cell epitopes from benzylpenicillin conjugated to human serum albumin and implication in penicillin allergy.
Allergy.
2018 Aug; 73(8):1662-1672. doi:
10.1111/all.13418. [PMID: 29355985] - Ying Li, Maoyuan Mu, Ling Yuan, Baimei Zeng, Shide Lin. Challenges in the early diagnosis of patients with acute liver failure induced by amatoxin poisoning: Two case reports.
Medicine.
2018 Jul; 97(27):e11288. doi:
10.1097/md.0000000000011288. [PMID: 29979397] - Cheng Cui, Xiang Zhang, Yang Wang, Shiying Lu, Huijun Lu, Qi Hui, Waqas Ahmad, Yan Cai, Xilin Liu, Lingjiu Liu, Fengfeng Shi, Yanyan Liu, Ke Zhao, FeiFei Zhai, Yangzhen Xiang, Pan Hu, Yansong Li, Honglin Ren, Ningyi Jin, Zengshan Liu. Acute and chronic toxicity assessment of benzylpenicillin G residue in heat-treated animal food products.
Chemosphere.
2018 Jul; 202(?):757-767. doi:
10.1016/j.chemosphere.2018.03.066. [PMID: 29605795] - Junpei Komagamine. The efficacy of high-dose penicillin G for pneumococcal pneumonia diagnosed based on initial comprehensive assessment at admission: an observational study.
BMC research notes.
2018 Jun; 11(1):399. doi:
10.1186/s13104-018-3510-7. [PMID: 29925417] - Kuan Lai, Nicolas Pinto-Sander, Daniel Richardson, Shanshan Wei, Kang Zeng. Syphilis gastritis: a case report.
International journal of STD & AIDS.
2018 06; 29(7):723-725. doi:
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Microbial pathogenesis.
2018 May; 118(?):220-229. doi:
10.1016/j.micpath.2018.03.035. [PMID: 29578067] - Yuma A Bijleveld, Timo R de Haan, Johanna H van der Lee, Floris Groenendaal, Peter H Dijk, Arno van Heijst, Rogier C J de Jonge, Koen P Dijkman, Henrica L M van Straaten, Monique Rijken, Inge A Zonnenberg, Filip Cools, Alexandra Zecic, Debbie H G M Nuytemans, Anton H van Kaam, Ron A A Mathôt. Evaluation of a System-Specific Function To Describe the Pharmacokinetics of Benzylpenicillin in Term Neonates Undergoing Moderate Hypothermia.
Antimicrobial agents and chemotherapy.
2018 04; 62(4):. doi:
10.1128/aac.02311-17. [PMID: 29378710] - Shijie Wen, Changyuan Wang, Yingjie Duan, Xiaokui Huo, Qiang Meng, Zhihao Liu, Shilei Yang, Yanna Zhu, Huijun Sun, Xiaodong Ma, Siyun Yang, Kexin Liu. OAT1 and OAT3 also mediate the drug-drug interaction between piperacillin and tazobactam.
International journal of pharmaceutics.
2018 Feb; 537(1-2):172-182. doi:
10.1016/j.ijpharm.2017.12.037. [PMID: 29277663] - Chang-Hua Chen. A Case Report of Penicillin-Tolerant Streptococcus mitis Endocarditis Chang-Hua Chen, MD, MSc, PhD.
The heart surgery forum.
2018 Jan; 21(1):E023-E025. doi:
10.1532/hsf.1751. [PMID: 29485959] - Karin Kipper, Charlotte I S Barker, Joseph F Standing, Mike Sharland, Atholl Johnston. Development of a Novel Multipenicillin Assay and Assessment of the Impact of Analyte Degradation: Lessons for Scavenged Sampling in Antimicrobial Pharmacokinetic Study Design.
Antimicrobial agents and chemotherapy.
2018 01; 62(1):. doi:
10.1128/aac.01540-17. [PMID: 29084754] - Mary Ann Sevick, Kathleen Woolf, Aditya Mattoo, Stuart D Katz, Huilin Li, David E St-Jules, Ram Jagannathan, Lu Hu, Mary Lou Pompeii, Lisa Ganguzza, Zhi Li, Alex Sierra, Stephen K Williams, David S Goldfarb. The Healthy Hearts and Kidneys (HHK) study: Design of a 2×2 RCT of technology-supported self-monitoring and social cognitive theory-based counseling to engage overweight people with diabetes and chronic kidney disease in multiple lifestyle changes.
Contemporary clinical trials.
2018 01; 64(?):265-273. doi:
10.1016/j.cct.2017.08.020. [PMID: 28867396] - Muhammad Adeel Shahzad, Syed Ali Raza Naqvi, Rashid Rasheed, Muhammad Yameen, Fozia Anjum, Muhammad Tauqeer Ahmed, Zaib Hussain, Syed Jawad Hussain Gillani. Radiolabeling of benzylpenicillin with lutetium-177: Quality control and biodistribution study to develop theranostic infection imaging agent.
Pakistan journal of pharmaceutical sciences.
2017 Nov; 30(6(Supplementary)):2349-2354. doi:
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Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2017 Sep; 107(Pt A):74-87. doi:
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Antimicrobial agents and chemotherapy.
2017 08; 61(8):. doi:
10.1128/aac.00252-17. [PMID: 28559267] - Lütfiye Öksüz, Nezahat Gürler. [Serotype distribution and antibiotic resistance of Streptococcus pneumoniae strains isolated from the adult patients in a Turkish üniversity hospital].
Mikrobiyoloji bulteni.
2017 Jul; 51(3):195-208. doi:
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Drug metabolism and disposition: the biological fate of chemicals.
2017 04; 45(4):409-417. doi:
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Journal of agricultural and food chemistry.
2017 Mar; 65(8):1778-1783. doi:
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Basic & clinical pharmacology & toxicology.
2017 Feb; 120(2):179-186. doi:
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Rinsho shinkeigaku = Clinical neurology.
2017 01; 57(1):37-40. doi:
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American journal of veterinary research.
2017 Jan; 78(1):17-26. doi:
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Drug metabolism and disposition: the biological fate of chemicals.
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Bioconjugate chemistry.
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PloS one.
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Antimicrobial agents and chemotherapy.
2014 Aug; 58(8):4495-503. doi:
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European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
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Journal of pharmaceutical and biomedical analysis.
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Research in veterinary science.
2013 Aug; 95(1):212-8. doi:
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Allergy.
2013 Jul; 68(7):899-905. doi:
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Biopharmaceutics & drug disposition.
2013 May; 34(4):236-46. doi:
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Analytical and bioanalytical chemistry.
2013 Mar; 405(8):2585-94. doi:
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Journal of pharmaceutical sciences.
2013 Mar; 102(3):1086-94. doi:
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Sexually transmitted diseases.
2013 Feb; 40(2):85-94. doi:
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PloS one.
2013; 8(7):e70102. doi:
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Journal of the South African Veterinary Association.
2013; 84(1):E1-5. doi:
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Pharmacological reports : PR.
2013; 65(2):505-12. doi:
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PloS one.
2013; 8(6):e66159. doi:
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Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia.
2012 Oct; 29(5):558-63. doi:
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Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology.
2012 Oct; 33(5):1179-81. doi:
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Retina (Philadelphia, Pa.).
2012 Oct; 32(9):1915-41. doi:
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Medizinische Monatsschrift fur Pharmazeuten.
2012 Oct; 35(10):367-77. doi:
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Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases.
2012 Jul; 86(4):415-8. doi:
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Drug testing and analysis.
2012 Feb; 4(2):140-4. doi:
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Neonatal network : NN.
2011 Sep; 30(5):320-8. doi:
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The Journal of pharmacology and experimental therapeutics.
2011 Sep; 338(3):841-9. doi:
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Analytica chimica acta.
2011 Aug; 699(2):232-41. doi:
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Journal of pediatric surgery.
2011 Aug; 46(8):1550-6. doi:
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Orvosi hetilap.
2011 May; 152(19):763-7. doi:
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Journal of veterinary pharmacology and therapeutics.
2011 Apr; 34(2):160-7. doi:
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Rapid communications in mass spectrometry : RCM.
2011 Jan; 25(1):25-32. doi:
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PloS one.
2011; 6(10):e25308. doi:
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Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi.
2010 Oct; 43(5):442-6. doi:
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African health sciences.
2010 Jun; 10(2):211-4. doi:
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Journal of agricultural and food chemistry.
2010 May; 58(9):5408-13. doi:
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International immunology.
2010 Apr; 22(4):281-8. doi:
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La Revue de medecine interne.
2009 Sep; 30(9):806-8. doi:
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Clinica chimica acta; international journal of clinical chemistry.
2009 Sep; 407(1-2):75-6. doi:
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Journal of cardiothoracic surgery.
2009 Jul; 4(?):35. doi:
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Neurosurgery.
2009 Mar; 64(3):568-75; discussioin 575. doi:
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Xenobiotica; the fate of foreign compounds in biological systems.
2009 Feb; 39(2):171-81. doi:
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Circulation.
2009 Jan; 119(1):19-27. doi:
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Internal medicine (Tokyo, Japan).
2009; 48(18):1667-9. doi:
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