Fluocinolone acetonide 21-acetate (BioDeep_00001103502)
代谢物信息卡片
化学式: C26H32F2O7 (494.2116)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(=O)OCC(=O)C12C(CC3C1(CC(C4(C3CC(C5=CC(=O)C=CC54C)F)F)O)C)OC(O2)(C)C
InChI: InChI=1S/C26H32F2O7/c1-13(29)33-12-20(32)26-21(34-22(2,3)35-26)10-15-16-9-18(27)17-8-14(30)6-7-23(17,4)25(16,28)19(31)11-24(15,26)5/h6-8,15-16,18-19,21,31H,9-12H2,1-5H3/t15?,16?,18-,19?,21+,23?,24?,25-,26+/m0/s1
描述信息
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D005938 - Glucocorticoids
D000893 - Anti-Inflammatory Agents
D018926 - Anti-Allergic Agents
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Mihoko Ohshima, Mio Miyake, Masanori Takeda, Michihiro Kamijima, Tatsuo Sakamoto. Staphylococcal enterotoxin B causes proliferation of sensory C-fibers and subsequent enhancement of neurogenic inflammation in rat skin.
The Journal of infectious diseases.
2011 Mar; 203(6):862-9. doi:
10.1093/infdis/jiq128. [PMID: 21252260] - Jiangbo Wang, Jiuyi Lu, Michael C Bond, Minyong Chen, Xiu-Rong Ren, H Kim Lyerly, Larry S Barak, Wei Chen. Identification of select glucocorticoids as Smoothened agonists: potential utility for regenerative medicine.
Proceedings of the National Academy of Sciences of the United States of America.
2010 May; 107(20):9323-8. doi:
10.1073/pnas.0910712107. [PMID: 20439738] - R Marks. The role of tazarotene in the treatment of psoriasis.
The British journal of dermatology.
1999 Apr; 140 Suppl 54(?):24-8. doi:
10.1046/j.1365-2133.1999.140s54024.x. [PMID: 10731131] - M Carbone, D Conrotto, M Carrozzo, R Broccoletti, S Gandolfo, C Scully. Topical corticosteroids in association with miconazole and chlorhexidine in the long-term management of atrophic-erosive oral lichen planus: a placebo-controlled and comparative study between clobetasol and fluocinonide.
Oral diseases.
1999 Jan; 5(1):44-9. doi:
10.1111/j.1601-0825.1999.tb00063.x. [PMID: 10218041] - H S Zackheim, M Kashani-Sabet, S Amin. Topical corticosteroids for mycosis fungoides. Experience in 79 patients.
Archives of dermatology.
1998 Aug; 134(8):949-54. doi:
10.1001/archderm.134.8.949. [PMID: 9722724] - D G Spoerke, S E Spoerke. Granuloma formation induced by spines of the cactus, Opuntia acanthocarpa.
Veterinary and human toxicology.
1991 Aug; 33(4):342-4. doi:
". [PMID: 1897129] - J M Plemons, T D Rees, N Y Zachariah. Absorption of a topical steroid and evaluation of adrenal suppression in patients with erosive lichen planus.
Oral surgery, oral medicine, and oral pathology.
1990 Jun; 69(6):688-93. doi:
10.1016/0030-4220(90)90349-w. [PMID: 2356081] - R D Zenoble, R J Kemppainen. Adrenocortical suppression by topically applied corticosteroids in healthy dogs.
Journal of the American Veterinary Medical Association.
1987 Sep; 191(6):685-8. doi:
. [PMID: 2824410] - B Jegasothy, C Jacobson, N Levine, L Millikan, E Olsen, S Pinnell, G Cole, G Weinstein, M Porter. Clobetasol propionate versus fluocinonide creams in psoriasis and eczema.
International journal of dermatology.
1985 Sep; 24(7):461-5. doi:
10.1111/j.1365-4362.1985.tb05821.x. [PMID: 3902682] - K Yamada, T Satoh. In vivo effects of glucocorticoids on serum corticosterone levels in rats.
Research communications in chemical pathology and pharmacology.
1985 Mar; 47(3):441-4. doi:
NULL. [PMID: 3992018] - Y Aizawa, H Kogo, K Yamada, N Inazu, T Matsudaira. [Effect of difluprednate on adrenocortical and gonadal function].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica.
1984 Dec; 84(6):553-61. doi:
10.1254/fpj.84.553. [PMID: 6519585] - E Novak, S F Francom, C A Schlagel. Adrenal suppression with high-potency corticosteroid ointment formulations in normal subjects.
Clinical therapeutics.
1983; 6(1):59-71. doi:
. [PMID: 6370438] - D D Munro. The effect of percutaneously absorbed steroids on hypothalamic--pituitary--adrenal function after intensive use in in-patients.
The British journal of dermatology.
1976 Mar; 94 suppl 12(?):67-76. doi:
10.1111/j.1365-2133.1976.tb02272.x. [PMID: 1268079]
