Alocrest (BioDeep_00001103433)
代谢物信息卡片
Alocrest
化学式: C45H54N4O8 (778.3941444000001)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCC1=CC2CC(C3=C(CN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC
InChI: InChI=1S/C45H54N4O8/c1-8-27-19-28-22-44(40(51)55-6,36-30(25-48(23-27)24-28)29-13-10-11-14-33(29)46-36)32-20-31-34(21-35(32)54-5)47(4)38-43(31)16-18-49-17-12-15-42(9-2,37(43)49)39(57-26(3)50)45(38,53)41(52)56-7/h10-15,19-21,28,37-39,46,53H,8-9,16-18,22-25H2,1-7H3/t28?,37-,38+,39+,42+,43+,44-,45-/m0/s1
描述信息
L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01C - Plant alkaloids and other natural products > L01CA - Vinca alkaloids and analogues
D050258 - Mitosis Modulators > D050256 - Antimitotic Agents > D050257 - Tubulin Modulators
D000970 - Antineoplastic Agents > D050256 - Antimitotic Agents
D000970 - Antineoplastic Agents > D014748 - Vinca Alkaloids
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Chen Guo, Xichun Zhu, Haoyang Yuan, Haoyu Liu, Yu Zhang, Tian Yin, Haibing He, Jingxin Gou, Xing Tang. Chitosan-Coated Liposomes: The Strategy to Reduce Intestinal Toxicity and Improve Bioavailability of Oral Vinorelbine.
AAPS PharmSciTech.
2022 Jun; 23(5):163. doi:
10.1208/s12249-022-02308-7. [PMID: 35680728] - L T van der Heijden, A Gebretensae, B Thijssen, L van Andel, A L Nijstad, Y Wang, H Rosing, A D R Huitema, J H Beijnen. A highly sensitive bioanalytical method for the quantification of vinblastine, vincristine, vinorelbine and 4-O-deacetylvinorelbine in human plasma using LC-MS/MS.
Journal of pharmaceutical and biomedical analysis.
2022 Jun; 215(?):114772. doi:
10.1016/j.jpba.2022.114772. [PMID: 35462284] - Zhichun Li, Liliang Ren. Study on Effects of Cyclophosphamide Combined with Vinorelbine in Advanced Small Cell Lung Cancer and Anteroposterior Changes in MRI.
Contrast media & molecular imaging.
2022; 2022(?):3104879. doi:
10.1155/2022/3104879. [PMID: 36043147] - Tianjiao Zeng, Mingshi Xu, Wanli Zhang, Xiaofan Gu, Fangqing Zhao, Xuan Liu, Xiongwen Zhang. Autophagy inhibition and microRNA‑199a‑5p upregulation in paclitaxel‑resistant A549/T lung cancer cells.
Oncology reports.
2021 07; 46(1):. doi:
10.3892/or.2021.8100. [PMID: 34080652] - Paola Orlandi, Marta Banchi, Greta Alì, Teresa Di Desidero, Elisabetta Fini, Gabriella Fontanini, Guido Bocci. Active metronomic vinorelbine schedules decrease plasma interleukin-2 levels in mice with Lewis lung carcinoma.
Journal of chemotherapy (Florence, Italy).
2021 May; 33(3):198-202. doi:
10.1080/1120009x.2020.1819069. [PMID: 32930084] - Xiu-Ying Li, Luan-Xia Shi, Xue-Min Yao, Ming Jing, Qin-Qing Li, Ying-Li Wang, Qing-Shan Li. Functional vinorelbine plus schisandrin B liposomes destroying tumor metastasis in treatment of gastric cancer.
Drug development and industrial pharmacy.
2021 Jan; 47(1):100-112. doi:
10.1080/03639045.2020.1862169. [PMID: 33295825] - Benay Özbay, Ecem Gürses, Hatice S Kemal, Evrim Şimşek, Hakan Kültürsay. Takotsubo syndrome early after treatment due to non cardiotoxic chemotherapy agents.
Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir.
2021 01; 49(1):72-75. doi:
10.5543/tkda.2020.25590. [PMID: 33390577] - Shuhang Wang, Jingxin Gou, Yue Wang, Xinyi Tan, Linxuan Zhao, Xiangqun Jin, Xing Tang. Synergistic Antitumor Efficacy Mediated by Liposomal Co-Delivery of Polymeric Micelles of Vinorelbine and Cisplatin in Non-Small Cell Lung Cancer.
International journal of nanomedicine.
2021; 16(?):2357-2372. doi:
10.2147/ijn.s290263. [PMID: 33790554] - Binghe Xu, Tao Sun, Shusen Wang, Yingcheng Lin. Metronomic therapy in advanced breast cancer and NSCLC: vinorelbine as a paradigm of recent progress.
Expert review of anticancer therapy.
2021 01; 21(1):71-79. doi:
10.1080/14737140.2021.1835478. [PMID: 33054438] - Hongyu Liu, Qingshan Fu, Yao Lu, Wenqiang Zhang, Peng Yu, Zhen Liu, Xiaosheng Sun. Anti-tubulin agent vinorelbine inhibits metastasis of cancer cells by regulating epithelial-mesenchymal transition.
European journal of medicinal chemistry.
2020 Aug; 200(?):112332. doi:
10.1016/j.ejmech.2020.112332. [PMID: 32473523] - Qian Li, Ren-Long Liang, Qian-Ru Yu, De-Qing Tian, Li-Na Zhao, Wen-Wen Wang, Hua Xiao, Xiao-Jia Yong, Xiao-Dong Peng. Efficacy and safety of cinobufacini injection combined with vinorelbine and cisplatin regimen chemotherapy for stage III/IV non-small cell lung cancer: A protocol for systematic review and meta-analysis of randomized controlled trials.
Medicine.
2020 Jul; 99(31):e21539. doi:
10.1097/md.0000000000021539. [PMID: 32756206] - David Rossi. Metronomic oral vinorelbine and lung cancer therapy during the COVID 19 pandemic: A single-center experience.
Lung cancer (Amsterdam, Netherlands).
2020 07; 145(?):83-84. doi:
10.1016/j.lungcan.2020.05.001. [PMID: 32416433] - Zheng Xiao, Yuan Jiang, Cheng-Qiong Wang, Shan-Shan Hu, Xiao-Rong Huang, Xiao-Fan Chen, Jun Huang, Li-Jing Shan, Yu-Hong Tang, Yu-He Wang, Qi-Hai Gong, Ji-Hong Feng, Xue Xiao, Xiao-Fei Li. Clinical efficacy and safety of aidi injection combination with vinorelbine and cisplatin for advanced non-small-cell lung carcinoma: A systematic review and meta-analysis of 54 randomized controlled trials.
Pharmacological research.
2020 03; 153(?):104637. doi:
10.1016/j.phrs.2020.104637. [PMID: 31935454] - Hailing Xu, Dongqing Lv, Yinnan Meng, Miao Wang, Wei Wang, Chao Zhou, Suna Zhou, Xiaofeng Chen, Haihua Yang. Endostar improved efficacy of concurrent chemoradiotherapy with vinorelbine plus carboplatin in locally advanced lung squamous cell carcinoma patients with high serum Lp(a) concentration.
Annals of palliative medicine.
2020 Mar; 9(2):298-307. doi:
10.21037/apm.2020.01.16. [PMID: 32075401] - Liang Kong, Shi-Meng Zhang, Jia-Hao Chu, Xin-Ze Liu, Lu Zhang, Si-Yu He, Si-Min Yang, Rui-Jun Ju, Xue-Tao Li. Tumor Microenvironmental Responsive Liposomes Simultaneously Encapsulating Biological and Chemotherapeutic Drugs for Enhancing Antitumor Efficacy of NSCLC.
International journal of nanomedicine.
2020; 15(?):6451-6468. doi:
10.2147/ijn.s258906. [PMID: 32922011] - Xi-En Wang, You-Hui Wang, Qiang Zhou, Min Peng, Jing Zhang, Mi Chen, Li-Juan Ma, Guo-Ming Xie. Immunomodulatory Effect of Lentinan on Aberrant T Subsets and Cytokines Profile in Non-small Cell Lung Cancer Patients.
Pathology oncology research : POR.
2020 Jan; 26(1):499-505. doi:
10.1007/s12253-018-0545-y. [PMID: 30460541] - Thomas Decker, Norbert Marschner, Axel Muendlein, Anja Welt, Volker Hagen, Jaqueline Rauh, Helge Schröder, Peter Jaehnig, Karin Potthoff, Christian Lerchenmüller. VicTORia: a randomised phase II study to compare vinorelbine in combination with the mTOR inhibitor everolimus versus vinorelbine monotherapy for second-line chemotherapy in advanced HER2-negative breast cancer.
Breast cancer research and treatment.
2019 Aug; 176(3):637-647. doi:
10.1007/s10549-019-05280-2. [PMID: 31115844] - Yue-Guo Wu, Kui-Wu Wang, Zheng-Rong Zhao, Ping Zhang, Hua Liu, Gui-Jiao Zhou, Yan Cheng, Wen-Jie Wu, Yi-Heng Cai, Bei-Li Wu, Feng-Yang Chen. A novel polysaccharide from Dendrobium devonianum serves as a TLR4 agonist for activating macrophages.
International journal of biological macromolecules.
2019 Jul; 133(?):564-574. doi:
10.1016/j.ijbiomac.2019.04.125. [PMID: 31004640] - Xue-Tao Li, Wei Tang, Hong-Jun Xie, Shuang Liu, Xiao-Li Song, Yao Xiao, Xin Wang, Lan Cheng, Gui-Rong Chen. The efficacy of RGD modified liposomes loaded with vinorelbine plus tetrandrine in treating resistant brain glioma.
Journal of liposome research.
2019 Mar; 29(1):21-34. doi:
10.1080/08982104.2017.1408649. [PMID: 29166813] - Ikumi Washio, Takeo Nakanishi, Naoki Ishiguro, Bojan Bister, Ikumi Tamai. Effect of endogenous multidrug resistance 1 and P-glycoprotein expression on anticancer drug resistance in colon cancer cell lines.
Biopharmaceutics & drug disposition.
2019 Jan; 40(1):32-43. doi:
10.1002/bdd.2167. [PMID: 30556139] - Krishnendu Pal, Vijay Sagar Madamsetty, Shamit Kumar Dutta, Debabrata Mukhopadhyay. Co-delivery of everolimus and vinorelbine via a tumor-targeted liposomal formulation inhibits tumor growth and metastasis in RCC.
International journal of nanomedicine.
2019; 14(?):5109-5123. doi:
10.2147/ijn.s204221. [PMID: 31371950] - Rong-Sheng Qin, Zhen-Hua Zhang, Neng-Ping Zhu, Fei Chen, Qian Guo, Hao-Wen Hu, Shao-Zhi Fu, Shan-Shan Liu, Yue Chen, Juan Fan, Yun-Wei Han. Enhanced antitumor and anti-angiogenic effects of metronomic Vinorelbine combined with Endostar on Lewis lung carcinoma.
BMC cancer.
2018 Oct; 18(1):967. doi:
10.1186/s12885-018-4738-2. [PMID: 30305062] - Chenghui Huang, Hui Wu, Haihua Zhu, Lan Liu, Ruifang Tian, Cong Xu, Xiaofei Li, Lihui Wang, Ke Cao, Peiguo Cao. [NAPD regimen for patients with recurrent refractory diffuse large B-cell lymphoma].
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences.
2018 Jul; 43(7):754-759. doi:
10.11817/j.issn.1672-7347.2018.07.009. [PMID: 30124211] - Meric A Altinoz, Aysel Ozpinar, Ebru Emekli Alturfan, Ilhan Elmaci. Vinorelbine's anti-tumor actions may depend on the mitotic apoptosis, autophagy and inflammation: hypotheses with implications for chemo-immunotherapy of advanced cancers and pediatric gliomas.
Journal of chemotherapy (Florence, Italy).
2018 Jul; 30(4):203-212. doi:
10.1080/1120009x.2018.1487149. [PMID: 30025492] - Xuenong Ouyang, Meiqi Shi, Fangwei Jie, Yuxian Bai, Peng Shen, Zhuang Yu, Xiuwen Wang, Cheng Huang, Min Tao, Zhehai Wang, Conghua Xie, Qi Wu, Yongqian Shu, Baohui Han, Fengchun Zhang, Yiping Zhang, Chunhong Hu, Xitao Ma, Yongjie Liang, Anlan Wang, Bing Lu, Yi Shi, Jinfei Chen, Zhixiang Zhuang, Jiejun Wang, Jianjin Huang, Changhui Wang, Chunxue Bai, Xin Zhou, Qiang Li, Feng Chen, Hao Yu, Jifeng Feng. Phase III study of dulanermin (recombinant human tumor necrosis factor-related apoptosis-inducing ligand/Apo2 ligand) combined with vinorelbine and cisplatin in patients with advanced non-small-cell lung cancer.
Investigational new drugs.
2018 04; 36(2):315-322. doi:
10.1007/s10637-017-0536-y. [PMID: 29134432] - Rahul Dhande, Amit Tyagi, Rakesh Kumar Sharma, Hetal Thakkar. 99mTc-vinorelbine tartrate loaded spherulites: Lung disposition study in Sprague-Dawley rats by gamma scintigraphy.
Pulmonary pharmacology & therapeutics.
2018 04; 49(?):36-45. doi:
10.1016/j.pupt.2018.01.002. [PMID: 29337265] - Yao Xiao, Lan Cheng, Hong-Jun Xie, Rui-Jun Ju, Xin Wang, Min Fu, Jing-Jing Liu, Xue-Tao Li. Vinorelbine cationic liposomes modified with wheat germ agglutinin for inhibiting tumor metastasis in treatment of brain glioma.
Artificial cells, nanomedicine, and biotechnology.
2018; 46(sup3):S524-S537. doi:
10.1080/21691401.2018.1501377. [PMID: 30299160] - Lakshmi Maurya, Sanjay Singh, Vijayakumar M Rajamanickam, Gopeshwar Narayan. Vitamin E TPGS Emulsified Vinorelbine Bitartrate Loaded Solid Lipid Nanoparticles (SLN): Formulation Development, Optimization and In vitro Characterization.
Current drug delivery.
2018; 15(8):1135-1145. doi:
10.2174/1567201815666180409105410. [PMID: 29629662] - Xiaoliang Zhao, Xiaohua Wen, Wei Wei, Yanjun Su, Jian You, Liqun Gong, Zhenfa Zhang, Meng Wang, Jianyu Xiao, Xiyin Wei, Changli Wang. Predictors for the efficacy of Endostar combined with neoadjuvant chemotherapy for stage IIIA (N2) NSCLC.
Cancer biomarkers : section A of Disease markers.
2017 Dec; 21(1):169-177. doi:
10.3233/cbm-170565. [PMID: 29036790] - Agnieszka Krawczyk, Dariusz Nowak, Piotr Jan Nowak, Gianluca Padula, Sylwia Kwiatkowska. Elevated exhalation of hydrogen peroxide in patients with non-small cell lung cancer is not affected by chemotherapy.
Redox report : communications in free radical research.
2017 Nov; 22(6):308-314. doi:
10.1080/13510002.2016.1229885. [PMID: 27611345] - Xiaobin Gong, Le Yang, Feng Zhang, Youtian Liang, Shouhong Gao, Ke Liu, Wansheng Chen. Validated UHPLC-MS/MS assay for quantitative determination of etoposide, gemcitabine, vinorelbine and their metabolites in patients with lung cancer.
Biomedical chromatography : BMC.
2017 Nov; 31(11):. doi:
10.1002/bmc.3989. [PMID: 28409868] - Kewen He, Xinzhao Wang, Xiyun Guan, Qian Yu, Qinghua Ma, Zhaoyun Liu, Zhiyong Yu. Vinorelbine Plus Gemcitabine or Cisplatin as First-line Treatment of HER2-negative Advanced Breast Cancer.
Anticancer research.
2017 10; 37(10):5647-5653. doi:
10.21873/anticanres.12000. [PMID: 28982882] - Jun-Jie Ma, Hui-Ping Liu. Efficacy of Aidi Injection () on overexpression of P-glycoprotein induced by vinorelbine and cisplatin regimen in patients with non-small cell lung cancer.
Chinese journal of integrative medicine.
2017 Jul; 23(7):504-509. doi:
10.1007/s11655-016-2511-4. [PMID: 27484766] - Jia-Shuan Wu, Li-Min Mu, Ying-Zi Bu, Lei Liu, Yan Yan, Ying-Jie Hu, Jing Bai, Jing-Ying Zhang, Weiyue Lu, Wan-Liang Lu. C-type natriuretic peptide-modified lipid vesicles: fabrication and use for the treatment of brain glioma.
Oncotarget.
2017 Jun; 8(25):40906-40921. doi:
10.18632/oncotarget.16641. [PMID: 28402948] - Hongyang Li, Li Sun, Hang Li, Xiaodan Lv, Herve Semukunzi, Ruiming Li, Jun Yu, Shengtao Yuan, Sensen Lin. DT-13, a saponin monomer 13 of the Dwarf lilyturf tuber, synergized with vinorelbine to induce mitotic arrest via activation of ERK signaling pathway in NCI-H1299 cells.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2017 May; 89(?):1277-1285. doi:
10.1016/j.biopha.2017.02.104. [PMID: 28320095] - Bjørg Sjøblom, Jūratė Šaltytė Benth, Bjørn H Grønberg, Vickie E Baracos, Michael B Sawyer, Øystein Fløtten, Marianne J Hjermstad, Nina Aass, Marit Jordhøy. Drug Dose Per Kilogram Lean Body Mass Predicts Hematologic Toxicity From Carboplatin-Doublet Chemotherapy in Advanced Non-Small-Cell Lung Cancer.
Clinical lung cancer.
2017 03; 18(2):e129-e136. doi:
10.1016/j.cllc.2016.09.008. [PMID: 27825639] - Teresa Di Desidero, Lisa Derosa, Luca Galli, Paola Orlandi, Andrea Fontana, Anna Fioravanti, Riccardo Marconcini, Mario Giorgi, Beatrice Campi, Alessandro Saba, Sara Lucchesi, Renato Felipetto, Romano Danesi, Giulio Francia, Giacomo Allegrini, Alfredo Falcone, Guido Bocci. Clinical, pharmacodynamic and pharmacokinetic results of a prospective phase II study on oral metronomic vinorelbine and dexamethasone in castration-resistant prostate cancer patients.
Investigational new drugs.
2016 12; 34(6):760-770. doi:
10.1007/s10637-016-0385-0. [PMID: 27557783] - Ramakrishna Samala, Helen R Thorsheim, Satyanarayana Goda, Kunal Taskar, Brunilde Gril, Patricia S Steeg, Quentin R Smith. Vinorelbine Delivery and Efficacy in the MDA-MB-231BR Preclinical Model of Brain Metastases of Breast Cancer.
Pharmaceutical research.
2016 12; 33(12):2904-2919. doi:
10.1007/s11095-016-2012-3. [PMID: 27541873] - Michal Wieczorek, Joseph Tcherkezian, Cynthia Bernier, Andrea E Prota, Sami Chaaban, Yannève Rolland, Claude Godbout, Mark A Hancock, Joseph C Arezzo, Ozhan Ocal, Cecilia Rocha, Natacha Olieric, Anita Hall, Hui Ding, Alexandre Bramoullé, Matthew G Annis, George Zogopoulos, Patrick G Harran, Thomas M Wilkie, Rolf A Brekken, Peter M Siegel, Michel O Steinmetz, Gordon C Shore, Gary J Brouhard, Anne Roulston. The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity.
Science translational medicine.
2016 11; 8(365):365ra159. doi:
10.1126/scitranslmed.aag1093. [PMID: 27856798] - Rocío Vázquez-Sánchez, Raúl Diez-Fernández, Santos Enrech-Frances, Ana Sánchez-Peña, Teresa Molina-García. Utility of day 8 blood tests on platinum plus vinorelbine regimen.
International journal of clinical pharmacy.
2016 Aug; 38(4):793-6. doi:
10.1007/s11096-016-0315-4. [PMID: 27164956] - Xue-Tao Li, Wei Tang, Ying Jiang, Xiao-Min Wang, Yan-Hong Wang, Lan Cheng, Xian-Sheng Meng. Multifunctional targeting vinorelbine plus tetrandrine liposomes for treating brain glioma along with eliminating glioma stem cells.
Oncotarget.
2016 Apr; 7(17):24604-22. doi:
10.18632/oncotarget.8360. [PMID: 27029055] - W-G Lan, Y-Z Hao, D-H Xu, P Wang, Y-L Zhou, L-B Ma. Serum human epididymis protein 4 is associated with the treatment response of concurrent chemoradiotherapy and prognosis in patients with locally advanced non-small cell lung cancer.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico.
2016 Apr; 18(4):375-80. doi:
10.1007/s12094-015-1375-y. [PMID: 26329292] - Cheng-Jeng Tai, Chien-Kai Wang, Chen-Jei Tai, Ching Tzao, Yung-Chang Lien, Chih-Cheng Hsieh, Cheng-I Hsieh, Hong-Cheng Wu, Chih-Hsiung Wu, Chun-Chao Chang, Ray-Jade Chen, Hung-Yi Chiou. Evaluation of Safety and Efficacy of Salvage Therapy With Sunitinib, Docetaxel (Tyxan) and Cisplatinum Followed by Maintenance Vinorelbine for Unresectable/Metastatic Nonsmall Cell Lung Cancer: Stage 1 of a Simon 2 Stage Clinical Trial. [Corrected].
Medicine.
2015 Dec; 94(52):e2303. doi:
10.1097/md.0000000000002303. [PMID: 26717366] - Shin Shomura, Hitoshi Suzuki, Masaki Yada, Chiaki Kondo. [Surgically Treated Clear Cell Carcinoma of the Lung; Report of a Case].
Kyobu geka. The Japanese journal of thoracic surgery.
2015 Nov; 68(11):955-7. doi:
NULL. [PMID: 26469265] - Haruka Shinke, Satohiro Masuda, Yousuke Togashi, Yasuaki Ikemi, Aiko Ozawa, Tomoko Sato, Young Hak Kim, Michiaki Mishima, Takaharu Ichimura, Joseph V Bonventre, Kazuo Matsubara. Urinary kidney injury molecule-1 and monocyte chemotactic protein-1 are noninvasive biomarkers of cisplatin-induced nephrotoxicity in lung cancer patients.
Cancer chemotherapy and pharmacology.
2015 Nov; 76(5):989-96. doi:
10.1007/s00280-015-2880-y. [PMID: 26407820] - Wan-xin Hou, He-gen Li, Zhi-wei Chen, Li-hua Zhu, Li-hong Zhao, Jian-hui Tian, Wei-jie Xu, Lei Zhou, Yi-lin Yao. [Treatment of Radical Resected NSCLC by Chinese Medicine Combined with Adjuvant Chemother- apy: a Clinical Study].
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
2015 Jun; 35(6):648-53. doi:
. [PMID: 26242112] - Eng Huat Tan, Daniel Shao Weng Tan, Wen Yun Li, Benjamin Haaland, Mei Kim Ang, Noan Min Chau, Chee Keong Toh, Iain Bee Huat Tan, Tong San Koh, Choon Hua Thng, Balram Chowbay, Kam Man Hui, Wan Teck Lim, Quan Sing Ng. Metronomic vinorelbine (oral) in combination with sorafenib in advanced non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands).
2015 Jun; 88(3):289-96. doi:
10.1016/j.lungcan.2015.04.001. [PMID: 25896396] - Andrea Camerini, Cheti Puccetti, Sara Donati, Chiara Valsuani, Maria Cristina Petrella, Gianna Tartarelli, Paolo Puccinelli, Domenico Amoroso. Metronomic oral vinorelbine as first-line treatment in elderly patients with advanced non-small cell lung cancer: results of a phase II trial (MOVE trial).
BMC cancer.
2015 May; 15(?):359. doi:
10.1186/s12885-015-1354-2. [PMID: 25943747] - Xue-Tao Li, Zhi-Yan Zhou, Ying Jiang, Mei-Li He, Lian-Qun Jia, Lin Zhao, Lan Cheng, Tian-Zhu Jia. PEGylated VRB plus quinacrine cationic liposomes for treating non-small cell lung cancer.
Journal of drug targeting.
2015 Apr; 23(3):232-43. doi:
10.3109/1061186x.2014.979829. [PMID: 25417934] - Hiroki Izumi, Hirokazu Touge, Tadashi Igishi, Haruhiko Makino, Shizuka Nishii-Ito, Miyako Takata, Hirofumi Nakazaki, Yasuto Ueda, Shingo Matsumoto, Masahiro Kodani, Jun Kurai, Kenichi Takeda, Tomohiro Sakamoto, Masaaki Yanai, Natsumi Tanaka, Chaitanya S Nirodi, Eiji Shimizu. Favorable effect of the combination of vinorelbine and dihydropyrimidine dehydrogenase‑inhibitory fluoropyrimidine in EGFR‑mutated lung adenocarcinoma: retrospective and in vitro studies.
International journal of oncology.
2015 Mar; 46(3):989-98. doi:
10.3892/ijo.2015.2815. [PMID: 25573239] - Mircea Gabriel Stoleriu, Volker Steger, Migdat Mustafi, Martin Michaelis, Jindrich Cinatl, Wilke Schneider, Andrea Nolte, Julia Kurz, Hans Peter Wendel, Christian Schlensak, Tobias Walker. A new strategy in the treatment of chemoresistant lung adenocarcinoma via specific siRNA transfection of SRF, E2F1, Survivin, HIF and STAT3.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.
2014 Nov; 46(5):877-86. doi:
10.1093/ejcts/ezu087. [PMID: 24627437] - Fatemeh Bahadori, Gülaçtı Topçu, Mehmet S Eroğlu, Hayat Onyüksel. A new lipid-based nano formulation of vinorelbine.
AAPS PharmSciTech.
2014 Oct; 15(5):1138-48. doi:
10.1208/s12249-014-0146-3. [PMID: 24871553] - Rong-Hua Zhu, Huan-De Li, Hua-Lin Cai, Zhi-Ping Jiang, Ping Xu, Li-Bo Dai, Wen-Xing Peng. Validated HILIC-MS/MS assay for determination of vindesine in human plasma: Application to a population pharmacokinetic study.
Journal of pharmaceutical and biomedical analysis.
2014 Aug; 96(?):31-6. doi:
10.1016/j.jpba.2014.03.017. [PMID: 24721203] - Shouhong Gao, Jingya Zhou, Feng Zhang, Haijun Miao, Yunlei Yun, Jin Feng, Xia Tao, Wansheng Chen. Rapid and sensitive liquid chromatography coupled with electrospray ionization tandem mass spectrometry method for the analysis of paclitaxel, docetaxel, vinblastine, and vinorelbine in human plasma.
Therapeutic drug monitoring.
2014 Jun; 36(3):394-400. doi:
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Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
2014 May; 9(5):702-9. doi:
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Journal of drug targeting.
2014 Jan; 22(1):57-66. doi:
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International journal of pharmaceutics.
2013 Sep; 454(1):472-7. doi:
10.1016/j.ijpharm.2013.06.032. [PMID: 23806812] - David Cucchiari, Alexia Bertuzzi, Piergiuseppe Colombo, Rita De Sanctis, Elisabetta Faucher, Nicola Fusco, Alessio Pellegrinelli, Paola Arosio, Claudio Angelini. Juxtaglomerular cell tumor: multicentric synchronous disease associated with paraneoplastic syndrome.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2013 May; 31(14):e240-2. doi:
10.1200/jco.2012.43.5545. [PMID: 23547072] - Anneli Dowler Nygaard, Karen-Lise Garm Spindler, Niels Pallisgaard, Rikke Fredslund Andersen, Anders Jakobsen. The prognostic value of KRAS mutated plasma DNA in advanced non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands).
2013 Mar; 79(3):312-7. doi:
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Neoplasma.
2013; 60(1):11-8. doi:
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Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.
2013; 29(7):757-60. doi:
10.2116/analsci.29.757. [PMID: 23842421] - Norihiro Kikuchi, Michiko Masuda, Tomohiro Tamura, Kensuke Nakazawa, Koji Kanemoto, Hiroaki Iijima, Hirokazu Ishikawa, Shinya Sato, Yukio Ishii. [Syndrome of inappropriate secretion of ADH following chemoradiation therapy].
Gan to kagaku ryoho. Cancer & chemotherapy.
2012 Nov; 39(11):1711-4. doi:
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Molecular pharmacology.
2012 Oct; 82(4):636-44. doi:
10.1124/mol.111.077099. [PMID: 22767610] - Li Guo, Shu-Ping Bai, Ling Zhao, Xiao-Hong Wang. Astragalus polysaccharide injection integrated with vinorelbine and cisplatin for patients with advanced non-small cell lung cancer: effects on quality of life and survival.
Medical oncology (Northwood, London, England).
2012 Sep; 29(3):1656-62. doi:
10.1007/s12032-011-0068-9. [PMID: 21928106] - Armelle Lavolé, Sophie Danel, Laurence Baudrin, Valérie Gounant, Anne-Marie Ruppert, Christelle Epaud, Laure Belmont, Lise Rosencher, Jacques Cadranel, Bernard Milleron. Routine administration of a single dose of cisplatin ≥ 75 mg/m2 after short hydration in an outpatient lung-cancer clinic.
Bulletin du cancer.
2012 Apr; 99(4):E43-8. doi:
10.1684/bdc.2012.1555. [PMID: 22450449] - Heather A Wakelee, Gary Middleton, David Dunlop, Rodryg Ramlau, Natasha Leighl, Desiree Hao, Arturo Lopez-Anaya, Petr Zatloukal, Charlotte D Jacobs. A phase I pharmacokinetic study of bexarotene with vinorelbine and cisplatin in patients with advanced non-small-cell lung cancer (NSCLC).
Cancer chemotherapy and pharmacology.
2012 Mar; 69(3):815-24. doi:
10.1007/s00280-011-1771-0. [PMID: 22057854] - Shih-Hung Yang, Chia-Chi Lin, Zhong-Zhe Lin, Yun-Long Tseng, Ruey-Long Hong. A phase I and pharmacokinetic study of liposomal vinorelbine in patients with advanced solid tumor.
Investigational new drugs.
2012 Feb; 30(1):282-9. doi:
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International journal of nanomedicine.
2012; 7(?):683-92. doi:
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Nan fang yi ke da xue xue bao = Journal of Southern Medical University.
2011 Dec; 31(12):2090-2. doi:
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Cancer chemotherapy and pharmacology.
2011 Dec; 68(6):1529-36. doi:
10.1007/s00280-011-1650-8. [PMID: 21519841] - Lakshmi Rajdev, Abdissa Negassa, Qun Dai, Gary Goldberg, Kathy Miller, Joseph A Sparano. Phase I trial of metronomic oral vinorelbine in patients with advanced cancer.
Cancer chemotherapy and pharmacology.
2011 Nov; 68(5):1119-24. doi:
10.1007/s00280-011-1580-5. [PMID: 21373895] - Peggy Gandia, Cecile Arellano, Quentin Chalret du Rieu, Isabelle Lochon, Mario Campone, Jean-Yves Pierga, Muriel Poublanc, Isabelle Hennebelle, Thomas Filleron, Etienne Chatelut, Jean-Pierre Delord. Unexpected high levels of vorinostat when combined with vinorelbine in patients with advanced cancer.
Current clinical pharmacology.
2011 Nov; 6(4):274-9. doi:
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Current drug safety.
2011 Jul; 6(3):185-93. doi:
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Journal of cancer research and clinical oncology.
2011 Jul; 137(7):1117-22. doi:
10.1007/s00432-011-0975-3. [PMID: 21298288] - Min Su, Mingming Zhao, Yanfei Luo, Xia Lin, Lishuang Xu, Haibing He, Hui Xu, Xing Tang. Evaluation of the efficacy, toxicity and safety of vinorelbine incorporated in a lipid emulsion.
International journal of pharmaceutics.
2011 Jun; 411(1-2):188-96. doi:
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Integrative cancer therapies.
2011 Jun; 10(2):127-37. doi:
10.1177/1534735410387599. [PMID: 21147812] - Esra Ertan, Hilal Soydinc, Aziz Yazar, Zeki Ustuner, Faruk Tas, Vildan Yasasever. Matrix metalloproteinase-9 decreased after chemotherapy in patients with non-small cell lung cancer.
Tumori.
2011 May; 97(3):286-9. doi:
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Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine.
2011 May; 9(5):525-30. doi:
10.3736/jcim20110509. [PMID: 21565138] - Makoto Niwa, Takashi Kawashiro. Sensitive measurement of vinorelbine in dog plasma by liquid chromatography-electrospray ionization tandem mass spectrometry utilizing transitions from double-charged precursor ions.
Biomedical chromatography : BMC.
2011 Apr; 25(4):517-23. doi:
10.1002/bmc.1477. [PMID: 20641009] - Jun Qian, Yixuan Wang, Jianhua Chang, Jian Zhang, Jialei Wang, Xichun Hu. Rapid and sensitive determination of vinorelbine in human plasma by liquid chromatography-tandem mass spectrometry and its pharmacokinetic application.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2011 Mar; 879(9-10):662-8. doi:
10.1016/j.jchromb.2011.01.039. [PMID: 21342795] - ChunLei Li, JingXia Cui, CaiXia Wang, Lan Zhang, Xian Xiu, YongFeng Li, Na Wei, YanHui Li, Li Zhang. Encapsulation of vinorelbine into cholesterol-polyethylene glycol coated vesicles: drug loading and pharmacokinetic studies.
The Journal of pharmacy and pharmacology.
2011 Mar; 63(3):376-84. doi:
10.1111/j.2042-7158.2010.01227.x. [PMID: 21749385] - Xue-tao Li, Lan Cheng, Tian-zhu Jia. [Preparation and physicochemical properties of vinorelbine liposomes].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
2011 Jan; 34(1):119-22. doi:
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Journal of natural products.
2010 Jun; 73(6):1075-9. doi:
10.1021/np100086x. [PMID: 20462230] - Chun-xiang Fan, Chun-li Lin, Lu Liang, Yan-yan Zhao, Jun Liu, Jie Cui, Qiu-min Yang, Yan-ling Wang, Ai-rong Zhang. [Enhancing effect of compound Kusheng injection in combination with chemotherapy for patients with advanced non-small cell lung cancer].
Zhonghua zhong liu za zhi [Chinese journal of oncology].
2010 Apr; 32(4):294-7. doi:
NULL. [PMID: 20510083] - Sutapa Sinha, Ying Cao, Shamit Dutta, Enfeng Wang, Debabrata Mukhopadhyay. VEGF neutralizing antibody increases the therapeutic efficacy of vinorelbine for renal cell carcinoma.
Journal of cellular and molecular medicine.
2010 Mar; 14(3):647-58. doi:
10.1111/j.1582-4934.2008.00578.x. [PMID: 19017359] - Xia Liu, Li Ma, Kehu Yang, Jinhui Tian. [Vinorelbine plus oxaliplatin versus vinorelbine plus cisplatin for advanced non-small cell lung cancer: a systematic review].
Zhongguo fei ai za zhi = Chinese journal of lung cancer.
2010 Feb; 13(2):112-7. doi:
10.3779/j.issn.1009-3419.2010.02.06. [PMID: 20673502] - Jian-Hui Tian, Ling-Shuang Liu, Zhi-Ming Shi, Zhi-Yi Zhou, Lin Wang. A randomized controlled pilot trial of 'Feiji Recipe' on quality of life of non-small cell lung cancer patients.
The American journal of Chinese medicine.
2010; 38(1):15-25. doi:
10.1142/s0192415x10007646. [PMID: 20128041] - Takaaki Yamada, Nobuaki Egashira, Maiko Imuta, Takahisa Yano, Yui Yamauchi, Hiroyuki Watanabe, Ryozo Oishi. Role of oxidative stress in vinorelbine-induced vascular endothelial cell injury.
Free radical biology & medicine.
2010 Jan; 48(1):120-7. doi:
10.1016/j.freeradbiomed.2009.10.032. [PMID: 19837156] - Carola W N Damen, Jurjen S Lagas, Hilde Rosing, Jan H M Schellens, Jos H Beijnen. The bioanalysis of vinorelbine and 4-O-deacetylvinorelbine in human and mouse plasma using high-performance liquid chromatography coupled with heated electrospray ionization tandem mass-spectrometry.
Biomedical chromatography : BMC.
2009 Dec; 23(12):1316-25. doi:
10.1002/bmc.1255. [PMID: 19488983] - Tong-Hsien Chow, Yi-Yu Lin, Jeng-Jong Hwang, Hsin-Ell Wang, Yun-Long Tseng, Victor Fei Pang, Ren-Shyan Liu, Wuu-Jyh Lin, Chung-Shi Yang, Gann Ting. Therapeutic efficacy evaluation of 111In-labeled PEGylated liposomal vinorelbine in murine colon carcinoma with multimodalities of molecular imaging.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2009 Dec; 50(12):2073-81. doi:
10.2967/jnumed.109.063503. [PMID: 19949027] - Tiefeng Cheng, Duanyun Si, Changxiao Liu. Rapid and sensitive LC-MS method for pharmacokinetic study of vinorelbine in rats.
Biomedical chromatography : BMC.
2009 Sep; 23(9):909-11. doi:
10.1002/bmc.1216. [PMID: 19353739] - Yi-Yu Lin, Jia-Je Li, Chih-Hsien Chang, Yi-Ching Lu, Jeng-Jong Hwang, Yun-Long Tseng, Wuu-Jyh Lin, Gann Ting, Hsin-Ell Wang. Evaluation of pharmacokinetics of 111In-labeled VNB-PEGylated liposomes after intraperitoneal and intravenous administration in a tumor/ascites mouse model.
Cancer biotherapy & radiopharmaceuticals.
2009 Aug; 24(4):453-60. doi:
10.1089/cbr.2008.0572. [PMID: 19694580] - Yong Shao, Han-Kun Zhang, Hong Ding, Hai-Tian Quan, Li-Guang Lou, Li-Hong Hu. Synthesis and structure-activity relationship studies of cytotoxic anhydrovinblastine amide derivatives.
Journal of natural products.
2009 Jun; 72(6):1170-7. doi:
10.1021/np900157t. [PMID: 19499938] - Koichi Furugaki, Junichi Yoshida, Ryosuke Ogawa, Iori Nagamatsu, Masafumi Miura, Koji Hokazono, Shuyo Umeda, Masahiro Shinohara, Masaharu Ekimura, Toshiyuki Ishimaru, Yuko Okamoto, Nobumichi Ogami, Sakae Nagaoka, Kazumi Ebe, Takuya Emoto, Asuka Seto, Masahiro Sugihara, Junko Yukawa, Kenichi Matsuo. [Chemotherapy for non-small cell lung cancer: split-dose administration of Cisplatin over four consecutive days and Vinorelbine ditartrate].
Gan to kagaku ryoho. Cancer & chemotherapy.
2009 Feb; 36(2):259-63. doi:
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The Journal of pharmacology and experimental therapeutics.
2009 Jan; 328(1):321-30. doi:
10.1124/jpet.108.141200. [PMID: 18948499] - Harold J Burstein, Yu-Hui Chen, Leroy M Parker, Jennifer Savoie, Jerry Younger, Irene Kuter, Paula D Ryan, Judy E Garber, Helen Chen, Susana M Campos, Lawrence N Shulman, Lyndsay N Harris, Rebecca Gelman, Eric P Winer. VEGF as a marker for outcome among advanced breast cancer patients receiving anti-VEGF therapy with bevacizumab and vinorelbine chemotherapy.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2008 Dec; 14(23):7871-7. doi:
10.1158/1078-0432.ccr-08-0593. [PMID: 19047116] - Feng Wan, Jian You, Yu Sun, Xing-Guo Zhang, Fu-De Cui, Yong-Zhong Du, Hong Yuan, Fu-Qiang Hu. Studies on PEG-modified SLNs loading vinorelbine bitartrate (I): preparation and evaluation in vitro.
International journal of pharmaceutics.
2008 Jul; 359(1-2):104-10. doi:
10.1016/j.ijpharm.2008.03.030. [PMID: 18450394] - Girolamo Del Monte, Patrizia Ferroni, Sabrina Mariotti, Emanuela Fossile, Fiorella Guadagni, Mario Roselli. Interleukin-2 inhalation therapy in renal cell cancer: a case report and review of the literature.
In vivo (Athens, Greece).
2008 Jul; 22(4):481-8. doi:
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Cancer chemotherapy and pharmacology.
2008 Jul; 62(2):331-3. doi:
10.1007/s00280-007-0636-z. [PMID: 17989977]