4-(Glutamylamino) butanoate (BioDeep_00000010906)

 

Secondary id: BioDeep_00001872319

human metabolite Endogenous


代谢物信息卡片


(2S)-2-amino-4-[(3-carboxypropyl)carbamoyl]butanoic acid

化学式: C9H16N2O5 (232.1059166)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 0.95%

分子结构信息

SMILES: C(CC(=O)O)CNC(=O)CCC(C(=O)O)N
InChI: InChI=1S/C9H16N2O5/c10-6(9(15)16)3-4-7(12)11-5-1-2-8(13)14/h6H,1-5,10H2,(H,11,12)(H,13,14)(H,15,16)/t6-/m0/s1

描述信息

4-(Glutamylamino) butanoate is a polyamine that is an intermediate in putrescine degradation II. Polyamines (the most common of which are putrescine , spermidine , and spermine ), a group of positively charged small molecules present in virtually all living organisms, have been implicated in many biological processes, including binding to nucleic acids, stabilizing membranes, and stimulating several enzymes. Although polyamines are clearly necessary for optimal cell growth, a surplus of polyamines can cause inhibition of growth and protein synthesis, and thus a balance is desired between the production and breakdown of polyamines. In putrescine degradation II, 4-(Glutamylamino) butanoate is a substrate for gamma-glutamyl-gamma-aminobutyrate hydrolase (puuD) and can be generated from the hydrolysis of gamma-glutamyl-gamma-aminobutyraldehyde. [HMDB]
4-(Glutamylamino) butanoate is a polyamine that is an intermediate in putrescine degradation II. Polyamines (the most common of which are putrescine , spermidine , and spermine ), a group of positively charged small molecules present in virtually all living organisms, have been implicated in many biological processes, including binding to nucleic acids, stabilizing membranes, and stimulating several enzymes. Although polyamines are clearly necessary for optimal cell growth, a surplus of polyamines can cause inhibition of growth and protein synthesis, and thus a balance is desired between the production and breakdown of polyamines. In putrescine degradation II, 4-(Glutamylamino) butanoate is a substrate for gamma-glutamyl-gamma-aminobutyrate hydrolase (puuD) and can be generated from the hydrolysis of gamma-glutamyl-gamma-aminobutyraldehyde.

同义名列表

42 个代谢物同义名

(2S)-2-amino-4-[(3-carboxypropyl)carbamoyl]butanoic acid; gamma-L-Glutamyl-gamma-aminobutyric acid; 4-(L-gamma-glutamylamino)Butanoic acid; gamma-Glutamyl-gamma aminobutyric acid; gamma-Glutamyl-gamma-aminobutyric acid; 4-(gamma-L-Glutamylamino)butanoic acid; gamma-L-Glutamyl-gamma-aminobutyrate; 4-(L-Glutam-5-ylamino)butanoic acid; 4-(g-L-Glutamylamino)butanoic acid; 4-(gamma-L-Glutamylamino)butanoate; gamma-Glutamyl-gamma-aminobutyrate; 4-(L-gamma-glutamylamino)Butanoate; N(5)-(3-Carboxypropyl)-L-glutamine; 4-(Γ-L-glutamylamino)butanoic acid; g-L-Glutamyl-g-aminobutyric acid; Γ-L-glutamyl-γ-aminobutyric acid; 4-(Glutamylamino) butanoic acid; 4-(L-Glutam-5-ylamino)butanoate; 4-(Γ-L-glutamylamino)butanoate; 4-(g-L-Glutamylamino)butanoate; Γ-glutamyl-γ-aminobutyric acid; 4-(Glutamylamino)butanoic acid; g-Glutamyl-g-aminobutyric acid; Γ-L-glutamyl-γ-aminobutyrate; g-L-Glutamyl-g-aminobutyrate; 4-(Glutamylamino) butanoate; 4-(Glutamylamino)butanoate; Γ-glutamyl-γ-aminobutyrate; g-Glutamyl-g-aminobutyrate; gamma-L-Glu-gamma-abu; gamma Glutamyl gaba; gamma-Glutamyl-gaba; g-Glutamyl-gaba; Γ glutamyl gaba; Γ-glutamyl-gaba; g Glutamyl gaba; gamma-Glu-gaba; Γ-L-glu-γ-abu; g-L-Glu-g-abu; Glutamylgaba; NSC609423; Glugaba



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

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BioCyc(2)

PlantCyc(0)

代谢反应

11 个相关的代谢反应过程信息。

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BioCyc(4)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(7)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

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