1-Oleoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phospho-L-serine (BioDeep_00001054141)

   


代谢物信息卡片


1-Oleoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phospho-L-serine

化学式: C36H58N5O13P (799.3768547999999)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCCCCCC=CCCCCCCCC(=O)OCC(COP(=O)(O)OCC(C(=O)O)N)OC(=O)CCCCCNC1=CC=C(C2=NON=C12)[N+](=O)[O-]
InChI: InChI=1S/C36H58N5O13P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17-20-32(42)50-25-28(26-51-55(48,49)52-27-29(37)36(44)45)53-33(43)21-18-16-19-24-38-30-22-23-31(41(46)47)35-34(30)39-54-40-35/h9-10,22-23,28-29,38H,2-8,11-21,24-27,37H2,1H3,(H,44,45)(H,48,49)/b10-9-/t28-,29+/m1/s1

描述信息

A 3-sn-phosphatidyl L-serine in which the phosphatidyl acyl groups at positions 1 and 2 are oleoyl and 6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl respectively.

同义名列表

1 个代谢物同义名

1-Oleoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phospho-L-serine



数据库引用编号

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分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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BioCyc(0)

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INOH(0)

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0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Yoko Nishimura, Satoshi Tadokoro, Masahiko Tanaka, Naohide Hirashima. Detection of asymmetric distribution of phospholipids by fluorescence resonance energy transfer. Biochemical and biophysical research communications. 2012 Apr; 420(4):926-30. doi: 10.1016/j.bbrc.2012.03.106. [PMID: 22475486]
  • Coen C Paulusma, Dineke E Folmer, Kam S Ho-Mok, D Rudi de Waart, Petra M Hilarius, Arthur J Verhoeven, Ronald P J Oude Elferink. ATP8B1 requires an accessory protein for endoplasmic reticulum exit and plasma membrane lipid flippase activity. Hepatology (Baltimore, Md.). 2008 Jan; 47(1):268-78. doi: 10.1002/hep.21950. [PMID: 17948906]
  • José Ma Araújo-Santos, Francisco Gamarro, Santiago Castanys, Andreas Herrmann, Thomas Pomorski. Rapid transport of phospholipids across the plasma membrane of Leishmania infantum. Biochemical and biophysical research communications. 2003 Jun; 306(1):250-5. doi: 10.1016/s0006-291x(03)00947-1. [PMID: 12788096]
  • R Bucki, P A Janmey, R Vegners, F Giraud, J C Sulpice. Involvement of phosphatidylinositol 4,5-bisphosphate in phosphatidylserine exposure in platelets: use of a permeant phosphoinositide-binding peptide. Biochemistry. 2001 Dec; 40(51):15752-61. doi: 10.1021/bi010899c. [PMID: 11747452]
  • D Kamp, T Sieberg, C W Haest. Inhibition and stimulation of phospholipid scrambling activity. Consequences for lipid asymmetry, echinocytosis, and microvesiculation of erythrocytes. Biochemistry. 2001 Aug; 40(31):9438-46. doi: 10.1021/bi0107492. [PMID: 11478914]
  • Y Ibuki, A Suzuki, R Goto. UVA irradiation induces energy-independent phospholipid-flip in mammalian plasma membrane. Photochemistry and photobiology. 2001 May; 73(5):513-7. doi: 10.1562/0031-8655(2001)073<0513:uiieip>2.0.co;2. [PMID: 11367573]
  • D Lee, N Hirashima, Y Kirino. Rapid transbilayer phospholipid redistribution associated with exocytotic release of neurotransmitters from cholinergic nerve terminals isolated from electric ray Narke japonica. Neuroscience letters. 2000 Sep; 291(1):21-4. doi: 10.1016/s0304-3940(00)01365-3. [PMID: 10962144]
  • P Meers, S Ali, R Erukulla, A S Janoff. Novel inner monolayer fusion assays reveal differential monolayer mixing associated with cation-dependent membrane fusion. Biochimica et biophysica acta. 2000 Jul; 1467(1):227-43. doi: 10.1016/s0005-2736(00)00224-8. [PMID: 10930525]
  • A van Oudenaarden, S G Boxer. Brownian ratchets: molecular separations in lipid bilayers supported on patterned arrays. Science (New York, N.Y.). 1999 Aug; 285(5430):1046-8. doi: 10.1126/science.285.5430.1046. [PMID: 10446046]
  • G Denisov, S Wanaski, P Luan, M Glaser, S McLaughlin. Binding of basic peptides to membranes produces lateral domains enriched in the acidic lipids phosphatidylserine and phosphatidylinositol 4,5-bisphosphate: an electrostatic model and experimental results. Biophysical journal. 1998 Feb; 74(2 Pt 1):731-44. doi: 10.1016/s0006-3495(98)73998-0. [PMID: 9533686]
  • A R Obringer, K W Dean, S R Channel, N S Rote. Aminophospholipid translocase activity in JEG-3; a choriocarcinoma model of cytotrophoblast differentiation. Placenta. 1997 Jul; 18(5-6):421-6. doi: 10.1016/s0143-4004(97)80042-2. [PMID: 9250704]
  • B G Schreurs, D S Lester. High-resolution fluorescent labeling of living cerebellar slices. Brain research. 1996 Aug; 730(1-2):125-32. doi: 10.1016/0006-8993(96)00439-8. [PMID: 8883896]
  • F Bassé, J G Stout, P J Sims, T Wiedmer. Isolation of an erythrocyte membrane protein that mediates Ca2+-dependent transbilayer movement of phospholipid. The Journal of biological chemistry. 1996 Jul; 271(29):17205-10. doi: 10.1074/jbc.271.29.17205. [PMID: 8663431]
  • C C Pak, R Blumenthal. Effect of X31 influenza virus fusion on phosphatidylserine asymmetry in erythrocytes. Biochimica et biophysica acta. 1996 Jan; 1278(1):98-104. doi: 10.1016/0005-2736(95)00193-x. [PMID: 8611613]
  • S C Liu, S J Yi, J R Mehta, P E Nichols, S K Ballas, P W Yacono, D E Golan, J Palek. Red cell membrane remodeling in sickle cell anemia. Sequestration of membrane lipids and proteins in Heinz bodies. The Journal of clinical investigation. 1996 Jan; 97(1):29-36. doi: 10.1172/jci118402. [PMID: 8550846]
  • P Williamson, E M Bevers, E F Smeets, P Comfurius, R A Schlegel, R F Zwaal. Continuous analysis of the mechanism of activated transbilayer lipid movement in platelets. Biochemistry. 1995 Aug; 34(33):10448-55. doi: 10.1021/bi00033a017. [PMID: 7654698]
  • E F Smeets, P Comfurius, E M Bevers, R F Zwaal. Calcium-induced transbilayer scrambling of fluorescent phospholipid analogs in platelets and erythrocytes. Biochimica et biophysica acta. 1994 Nov; 1195(2):281-6. doi: 10.1016/0005-2736(94)90268-2. [PMID: 7947922]
  • D L Bratton. Polyamine inhibition of transbilayer movement of plasma membrane phospholipids in the erythrocyte ghost. The Journal of biological chemistry. 1994 Sep; 269(36):22517-23. doi: 10.1016/s0021-9258(17)31677-0. [PMID: 8077200]
  • J Connor, C C Pak, A J Schroit. Exposure of phosphatidylserine in the outer leaflet of human red blood cells. Relationship to cell density, cell age, and clearance by mononuclear cells. The Journal of biological chemistry. 1994 Jan; 269(4):2399-404. doi: 10.1016/s0021-9258(17)41959-4. [PMID: 8300565]
  • J Connor, K Gillum, A J Schroit. Maintenance of lipid asymmetry in red blood cells and ghosts: effect of divalent cations and serum albumin on the transbilayer distribution of phosphatidylserine. Biochimica et biophysica acta. 1990 Jun; 1025(1):82-6. doi: 10.1016/0005-2736(90)90193-r. [PMID: 2369579]
  • J Connor, C Bucana, I J Fidler, A J Schroit. Differentiation-dependent expression of phosphatidylserine in mammalian plasma membranes: quantitative assessment of outer-leaflet lipid by prothrombinase complex formation. Proceedings of the National Academy of Sciences of the United States of America. 1989 May; 86(9):3184-8. doi: 10.1073/pnas.86.9.3184. [PMID: 2717615]
  • Y M Denkins, A J Schroit. Phosphatidylserine decarboxylase: generation of asymmetric vesicles and determination of the transbilayer distribution of fluorescent phosphatidylserine in model membrane systems. Biochimica et biophysica acta. 1986 Nov; 862(2):343-51. doi: 10.1016/0005-2736(86)90237-3. [PMID: 3535891]
  • A J Schroit, J W Madsen, Y Tanaka. In vivo recognition and clearance of red blood cells containing phosphatidylserine in their plasma membranes. The Journal of biological chemistry. 1985 Apr; 260(8):5131-8. doi: 10.1016/s0021-9258(18)89189-x. [PMID: 3988747]
  • Y Tanaka, A J Schroit. Insertion of fluorescent phosphatidylserine into the plasma membrane of red blood cells. Recognition by autologous macrophages. The Journal of biological chemistry. 1983 Sep; 258(18):11335-43. doi: 10.1016/s0021-9258(17)44422-x. [PMID: 6885820]