3-(Propionyloxy)-4-(trimethylaminio)butanoic acid (BioDeep_00001047992)

   


代谢物信息卡片


3-(Propionyloxy)-4-(trimethylaminio)butanoic acid

化学式: C10H20NO4+ (218.1392)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCC(=O)OC(CC(=O)O)C[N+](C)(C)C
InChI: InChI=1S/C10H19NO4/c1-5-10(14)15-8(6-9(12)13)7-11(2,3)4/h8H,5-7H2,1-4H3/p+1

描述信息

同义名列表

1 个代谢物同义名

3-(Propionyloxy)-4-(trimethylaminio)butanoic acid



数据库引用编号

2 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Réjane Morand, Liliane Todesco, Massimiliano Donzelli, David Fischer-Barnicol, Peter J Mullen, Stephan Krähenbühl. Effect of short- and long-term treatment with valproate on carnitine homeostasis in humans. Therapeutic drug monitoring. 2012 Aug; 34(4):406-14. doi: 10.1097/ftd.0b013e3182608e2f. [PMID: 22743351]
  • Vittorio Sirolli, Claudia Rossi, Augusto Di Castelnuovo, Paolo Felaco, Luigi Amoroso, Mirco Zucchelli, Domenico Ciavardelli, Carmine Di Ilio, Paolo Sacchetta, Sergio Bernardini, Arduino Arduini, Mario Bonomini, Andrea Urbani. Toward personalized hemodialysis by low molecular weight amino-containing compounds: future perspective of patient metabolic fingerprint. Blood transfusion = Trasfusione del sangue. 2012 May; 10 Suppl 2(?):s78-88. doi: 10.2450/2012.012s. [PMID: 22890273]
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  • Gloria Schlegel, Janine Keller, Frank Hirche, Stefanie Geissler, Frieder J Schwarz, Robert Ringseis, Gabriele I Stangl, Klaus Eder. Expression of genes involved in hepatic carnitine synthesis and uptake in dairy cows in the transition period and at different stages of lactation. BMC veterinary research. 2012 Mar; 8(?):28. doi: 10.1186/1746-6148-8-28. [PMID: 22417075]
  • Charles Desmarchelier, Christoph Dahlhoff, Sylvia Keller, Manuela Sailer, Gerhard Jahreis, Hannelore Daniel. C57Bl/6 N mice on a western diet display reduced intestinal and hepatic cholesterol levels despite a plasma hypercholesterolemia. BMC genomics. 2012 Mar; 13(?):84. doi: 10.1186/1471-2164-13-84. [PMID: 22394543]
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  • Sandro La Vignera, Rosita Condorelli, Enzo Vicari, Rosario D'Agata, Aldo E Calogero. Endothelial antioxidant compound prolonged the endothelial antiapoptotic effects registered after tadalafil treatment in patients with arterial erectile dysfunction. Journal of andrology. 2012 Mar; 33(2):170-5. doi: 10.2164/jandrol.111.013342. [PMID: 21546612]
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  • Heidi L Peters, James J Pitt, Leonie R Wood, Natasha J Hamilton, Joseph P Sarsero, Nicole E Buck. Mouse models for methylmalonic aciduria. PloS one. 2012; 7(7):e40609. doi: 10.1371/journal.pone.0040609. [PMID: 22792386]
  • Brante P Sampey, Alex J Freemerman, Jimmy Zhang, Pei-Fen Kuan, Joseph A Galanko, Thomas M O'Connell, Olga R Ilkayeva, Michael J Muehlbauer, Robert D Stevens, Christopher B Newgard, Heather A Brauer, Melissa A Troester, Liza Makowski. Metabolomic profiling reveals mitochondrial-derived lipid biomarkers that drive obesity-associated inflammation. PloS one. 2012; 7(6):e38812. doi: 10.1371/journal.pone.0038812. [PMID: 22701716]
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  • Yunqiu Xia, Qing Li, Weizhen Zhong, Jing Dong, Zhulin Wang, Chunbo Wang. L-carnitine ameliorated fatty liver in high-calorie diet/STZ-induced type 2 diabetic mice by improving mitochondrial function. Diabetology & metabolic syndrome. 2011 Nov; 3(?):31. doi: 10.1186/1758-5996-3-31. [PMID: 22082204]
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  • Janine Keller, Robert Ringseis, Steffen Priebe, Reinhard Guthke, Holger Kluge, Klaus Eder. Effect of L-carnitine on the hepatic transcript profile in piglets as animal model. Nutrition & metabolism. 2011 Oct; 8(?):76. doi: 10.1186/1743-7075-8-76. [PMID: 22040461]
  • Lena Burri, Bodil Bjørndal, Hege Wergedahl, Kjetil Berge, Pavol Bohov, Asbjørn Svardal, Rolf K Berge. Tetradecylthioacetic acid increases hepatic mitochondrial β-oxidation and alters fatty acid composition in a mouse model of chronic inflammation. Lipids. 2011 Aug; 46(8):679-89. doi: 10.1007/s11745-011-3536-2. [PMID: 21479675]
  • Jing Chen, Xiaoyan Zhang, Rui Cao, Xin Lu, Sumin Zhao, Agnes Fekete, Qiang Huang, Philippe Schmitt-Kopplin, Yisheng Wang, Zhiliang Xu, Xiaoping Wan, Xiaohua Wu, Naiqing Zhao, Congjian Xu, Guowang Xu. Serum 27-nor-5β-cholestane-3,7,12,24,25 pentol glucuronide discovered by metabolomics as potential diagnostic biomarker for epithelium ovarian cancer. Journal of proteome research. 2011 May; 10(5):2625-32. doi: 10.1021/pr200173q. [PMID: 21456628]
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  • Richard J Bloomer, Tyler M Farney, John F Trepanowski, Cameron G McCarthy, Robert E Canale. Effect of betaine supplementation on plasma nitrate/nitrite in exercise-trained men. Journal of the International Society of Sports Nutrition. 2011 Mar; 8(?):5. doi: 10.1186/1550-2783-8-5. [PMID: 21414230]
  • David S Millington, Robert D Stevens. Acylcarnitines: analysis in plasma and whole blood using tandem mass spectrometry. Methods in molecular biology (Clifton, N.J.). 2011; 708(?):55-72. doi: 10.1007/978-1-61737-985-7_3. [PMID: 21207283]
  • Ali Karadeniz, Nejdet Simsek, Emre Karakus, Serap Yildirim, Adem Kara, Ismail Can, Fikrullah Kisa, Habib Emre, Mehmet Turkeli. Royal jelly modulates oxidative stress and apoptosis in liver and kidneys of rats treated with cisplatin. Oxidative medicine and cellular longevity. 2011; 2011(?):981793. doi: 10.1155/2011/981793. [PMID: 21904651]
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  • Mohamed M Sayed-Ahmed. Progression of cyclophosphamide-induced acute renal metabolic damage in carnitine-depleted rat model. Clinical and experimental nephrology. 2010 Oct; 14(5):418-26. doi: 10.1007/s10157-010-0321-0. [PMID: 20652348]
  • Yosuke Shigematsu, Ikue Hata, Go Tajima. Useful second-tier tests in expanded newborn screening of isovaleric acidemia and methylmalonic aciduria. Journal of inherited metabolic disease. 2010 Oct; 33(Suppl 2):S283-8. doi: 10.1007/s10545-010-9111-9. [PMID: 20440648]
  • Adronie Verbrugghe, Geert P J Janssens, Eva Meininger, Sylvie Daminet, Koen Piron, Lynn Vanhaecke, Birgitte Wuyts, Johan Buyse, Myriam Hesta. Intestinal fermentation modulates postprandial acylcarnitine profile and nitrogen metabolism in a true carnivore: the domestic cat ( Felis catus). The British journal of nutrition. 2010 Oct; 104(7):972-9. doi: 10.1017/s0007114510001558. [PMID: 20420757]
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  • Kang-Hsiang Cheng, Mei-Ying Liu, Chuan-Hong Kao, Yann-Jang Chen, Kwang-Jen Hsiao, Tze-Tze Liu, Hsiang-Yu Lin, Cheng-Hung Huang, Chuan-Chi Chiang, Huey-Jane Ho, Shuan-Pei Lin, Ni-Chung Lee, Wuh-Liang Hwu, Ju-Li Lin, Ping-Yao Hung, Dau-Ming Niu. Newborn screening for methylmalonic aciduria by tandem mass spectrometry: 7 years' experience from two centers in Taiwan. Journal of the Chinese Medical Association : JCMA. 2010 Jun; 73(6):314-8. doi: 10.1016/s1726-4901(10)70067-8. [PMID: 20603089]
  • Debby P Y Koonen, Miranda M Y Sung, Cindy K C Kao, Vernon W Dolinsky, Timothy R Koves, Olga Ilkayeva, René L Jacobs, Dennis E Vance, Peter E Light, Deborah M Muoio, Maria Febbraio, Jason R B Dyck. Alterations in skeletal muscle fatty acid handling predisposes middle-aged mice to diet-induced insulin resistance. Diabetes. 2010 Jun; 59(6):1366-75. doi: 10.2337/db09-1142. [PMID: 20299464]
  • Richard J Bloomer, Tyler M Farney, John F Trepanowski, Cameron G McCarthy, Robert E Canale, Brian K Schilling. Comparison of pre-workout nitric oxide stimulating dietary supplements on skeletal muscle oxygen saturation, blood nitrate/nitrite, lipid peroxidation, and upper body exercise performance in resistance trained men. Journal of the International Society of Sports Nutrition. 2010 May; 7(?):16. doi: 10.1186/1550-2783-7-16. [PMID: 20459623]
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  • Dominga Lapi, Lina Sabatino, Giovanna Giuseppina Altobelli, Paolo Mondola, Vincenzo Cimini, Antonio Colantuoni. Effects of propionyl-L-carnitine on ischemia-reperfusion injury in hamster cheek pouch microcirculation. Frontiers in physiology. 2010; 1(?):132. doi: 10.3389/fphys.2010.00132. [PMID: 21423374]
  • Kyoko Yokoi, Tetsuya Ito, Yasuhiro Maeda, Yoko Nakajima, Yukihisa Kurono, Naruji Sugiyama, Hajime Togari. A case of holocarboxylase synthetase deficiency with insufficient response to prenatal biotin therapy. Brain & development. 2009 Nov; 31(10):775-8. doi: 10.1016/j.braindev.2008.12.016. [PMID: 19201116]
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  • Adronie Verbrugghe, Myriam Hesta, Kris Gommeren, Sylvie Daminet, Birgitte Wuyts, Johan Buyse, Geert P J Janssens. Oligofructose and inulin modulate glucose and amino acid metabolism through propionate production in normal-weight and obese cats. The British journal of nutrition. 2009 Sep; 102(5):694-702. doi: 10.1017/s0007114509288982. [PMID: 19267948]
  • Chuan-Hong Kao, Mei-Ying Liu, Tze-Tze Liu, Kwang-Jen Hsiao, Kang-Hsiang Cheng, Cheng-Hung Huang, Hsiang-Yu Lin, Dau-Ming Niu. Growth hormone therapy in neonatal patients with methylmalonic acidemia. Journal of the Chinese Medical Association : JCMA. 2009 Sep; 72(9):462-7. doi: 10.1016/s1726-4901(09)70408-3. [PMID: 19762313]
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