2-(Butanoyloxy)-3-carboxy-N,N,N-trimethylpropan-1-aminium (BioDeep_00001046406)

   


代谢物信息卡片


2-(Butanoyloxy)-3-carboxy-N,N,N-trimethylpropan-1-aminium

化学式: C11H22NO4+ (232.1548752)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCC(=O)OC(CC(=O)O)C[N+](C)(C)C
InChI: InChI=1S/C11H21NO4/c1-5-6-11(15)16-9(7-10(13)14)8-12(2,3)4/h9H,5-8H2,1-4H3/p+1

描述信息

同义名列表

1 个代谢物同义名

2-(Butanoyloxy)-3-carboxy-N,N,N-trimethylpropan-1-aminium



数据库引用编号

1 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Natalie M Gallant, Karen Leydiker, Hao Tang, Lisa Feuchtbaum, Fred Lorey, Rebecca Puckett, Joshua L Deignan, Julie Neidich, Naghmeh Dorrani, Erica Chang, Bruce A Barshop, Stephen D Cederbaum, Jose E Abdenur, Raymond Y Wang. Biochemical, molecular, and clinical characteristics of children with short chain acyl-CoA dehydrogenase deficiency detected by newborn screening in California. Molecular genetics and metabolism. 2012 May; 106(1):55-61. doi: 10.1016/j.ymgme.2012.02.007. [PMID: 22424739]
  • Charles Desmarchelier, Christoph Dahlhoff, Sylvia Keller, Manuela Sailer, Gerhard Jahreis, Hannelore Daniel. C57Bl/6 N mice on a western diet display reduced intestinal and hepatic cholesterol levels despite a plasma hypercholesterolemia. BMC genomics. 2012 Mar; 13(?):84. doi: 10.1186/1471-2164-13-84. [PMID: 22394543]
  • Kim M Huffman, Leanne M Redman, Lawrence R Landerman, Carl F Pieper, Robert D Stevens, Michael J Muehlbauer, Brett R Wenner, James R Bain, Virginia B Kraus, Christopher B Newgard, Eric Ravussin, William E Kraus. Caloric restriction alters the metabolic response to a mixed-meal: results from a randomized, controlled trial. PloS one. 2012; 7(4):e28190. doi: 10.1371/journal.pone.0028190. [PMID: 22523532]
  • Yunqiu Xia, Qing Li, Weizhen Zhong, Jing Dong, Zhulin Wang, Chunbo Wang. L-carnitine ameliorated fatty liver in high-calorie diet/STZ-induced type 2 diabetic mice by improving mitochondrial function. Diabetology & metabolic syndrome. 2011 Nov; 3(?):31. doi: 10.1186/1758-5996-3-31. [PMID: 22082204]
  • Kuan-Hsing Chen, Mei-Ling Cheng, Yu-Hong Jing, Daniel Tsun-Yee Chiu, Ming-Shi Shiao, Jan-Kan Chen. Resveratrol ameliorates metabolic disorders and muscle wasting in streptozotocin-induced diabetic rats. American journal of physiology. Endocrinology and metabolism. 2011 Nov; 301(5):E853-63. doi: 10.1152/ajpendo.00048.2011. [PMID: 21791624]
  • A Drousiotou, I DiMeo, R Mineri, Th Georgiou, G Stylianidou, V Tiranti. Ethylmalonic encephalopathy: application of improved biochemical and molecular diagnostic approaches. Clinical genetics. 2011 Apr; 79(4):385-90. doi: 10.1111/j.1399-0004.2010.01457.x. [PMID: 20528888]
  • Satish C Kalhan, Lining Guo, John Edmison, Srinivasan Dasarathy, Arthur J McCullough, Richard W Hanson, Mike Milburn. Plasma metabolomic profile in nonalcoholic fatty liver disease. Metabolism: clinical and experimental. 2011 Mar; 60(3):404-13. doi: 10.1016/j.metabol.2010.03.006. [PMID: 20423748]
  • Anna Floegel, Dagmar Drogan, Rui Wang-Sattler, Cornelia Prehn, Thomas Illig, Jerzy Adamski, Hans-Georg Joost, Heiner Boeing, Tobias Pischon. Reliability of serum metabolite concentrations over a 4-month period using a targeted metabolomic approach. PloS one. 2011; 6(6):e21103. doi: 10.1371/journal.pone.0021103. [PMID: 21698256]
  • Oliver Fiehn, W Timothy Garvey, John W Newman, Kerry H Lok, Charles L Hoppel, Sean H Adams. Plasma metabolomic profiles reflective of glucose homeostasis in non-diabetic and type 2 diabetic obese African-American women. PloS one. 2010 Dec; 5(12):e15234. doi: 10.1371/journal.pone.0015234. [PMID: 21170321]
  • Makoto Takei, Yosuke Ando, Wataru Saitoh, Tomoe Tanimoto, Naoki Kiyosawa, Sunao Manabe, Atsushi Sanbuissho, Osamu Okazaki, Haruo Iwabuchi, Takashi Yamoto, Klaus-Peter Adam, James E Weiel, John A Ryals, Michael V Milburn, Lining Guo. Ethylene glycol monomethyl ether-induced toxicity is mediated through the inhibition of flavoprotein dehydrogenase enzyme family. Toxicological sciences : an official journal of the Society of Toxicology. 2010 Dec; 118(2):643-52. doi: 10.1093/toxsci/kfq211. [PMID: 20616209]
  • Sabrina Forni, Xiaowei Fu, Susan E Palmer, Lawrence Sweetman. Rapid determination of C4-acylcarnitine and C5-acylcarnitine isomers in plasma and dried blood spots by UPLC-MS/MS as a second tier test following flow-injection MS/MS acylcarnitine profile analysis. Molecular genetics and metabolism. 2010 Sep; 101(1):25-32. doi: 10.1016/j.ymgme.2010.05.012. [PMID: 20591710]
  • Roberta Leonardi, Jerold E Rehg, Charles O Rock, Suzanne Jackowski. Pantothenate kinase 1 is required to support the metabolic transition from the fed to the fasted state. PloS one. 2010 Jun; 5(6):e11107. doi: 10.1371/journal.pone.0011107. [PMID: 20559429]
  • Fengxia Zhang, Zhenhua Jia, Peng Gao, Hongwei Kong, Xiang Li, Xin Lu, Yiling Wu, Guowang Xu. Metabonomics study of urine and plasma in depression and excess fatigue rats by ultra fast liquid chromatography coupled with ion trap-time of flight mass spectrometry. Molecular bioSystems. 2010 May; 6(5):852-61. doi: 10.1039/b914751a. [PMID: 20567771]
  • Judith L Flanagan, Peter A Simmons, Joseph Vehige, Mark Dp Willcox, Qian Garrett. Role of carnitine in disease. Nutrition & metabolism. 2010 Apr; 7(?):30. doi: 10.1186/1743-7075-7-30. [PMID: 20398344]
  • Bianca T van Maldegem, Marinus Duran, Ronald J A Wanders, Hans R Waterham, Frits A Wijburg. Flavin adenine dinucleotide status and the effects of high-dose riboflavin treatment in short-chain acyl-CoA dehydrogenase deficiency. Pediatric research. 2010 Mar; 67(3):304-8. doi: 10.1203/pdr.0b013e3181cbd57b. [PMID: 19952864]
  • Fengxia Zhang, Zhenhua Jia, Peng Gao, Hongwei Kong, Xiang Li, Jing Chen, Qin Yang, Peiyuan Yin, Jiangshan Wang, Xin Lu, Famei Li, Yiling Wu, Guowang Xu. Metabonomics study of atherosclerosis rats by ultra fast liquid chromatography coupled with ion trap-time of flight mass spectrometry. Talanta. 2009 Aug; 79(3):836-44. doi: 10.1016/j.talanta.2009.05.010. [PMID: 19576453]
  • Reena Jethva, Michael J Bennett, Jerry Vockley. Short-chain acyl-coenzyme A dehydrogenase deficiency. Molecular genetics and metabolism. 2008 Dec; 95(4):195-200. doi: 10.1016/j.ymgme.2008.09.007. [PMID: 18977676]
  • Stuart G Beattie, Eric Goetzman, Thomas Conlon, Sean Germain, Glenn Walter, Martha Campbell-Thompson, Dietrich Matern, Jerry Vockley, Terence R Flotte. Biochemical correction of short-chain acyl-coenzyme A dehydrogenase deficiency after portal vein injection of rAAV8-SCAD. Human gene therapy. 2008 Jun; 19(6):579-88. doi: 10.1089/hum.2007.168. [PMID: 18500942]
  • Ingrid Tein, Orly Elpeleg, Bruria Ben-Zeev, Stanley H Korman, Alexander Lossos, Dorit Lev, Tally Lerman-Sagie, Esther Leshinsky-Silver, Jerry Vockley, Gerard T Berry, Anne-Marie Lamhonwah, Dietrich Matern, Charles R Roe, Niels Gregersen. Short-chain acyl-CoA dehydrogenase gene mutation (c.319C>T) presents with clinical heterogeneity and is candidate founder mutation in individuals of Ashkenazi Jewish origin. Molecular genetics and metabolism. 2008 Feb; 93(2):179-89. doi: 10.1016/j.ymgme.2007.09.021. [PMID: 18054510]
  • Devin Oglesbee, Miao He, Nilanjana Majumder, Jerry Vockley, Ayesha Ahmad, Brad Angle, Barbara Burton, Joel Charrow, Regina Ensenauer, Can H Ficicioglu, Laura Davis Keppen, Deborah Marsden, Silvia Tortorelli, Si Houn Hahn, Dietrich Matern. Development of a newborn screening follow-up algorithm for the diagnosis of isobutyryl-CoA dehydrogenase deficiency. Genetics in medicine : official journal of the American College of Medical Genetics. 2007 Feb; 9(2):108-16. doi: 10.1097/gim.0b013e31802f78d6. [PMID: 17304052]
  • B Merinero, C Pérez-Cerdá, P Ruiz Sala, I Ferrer, M J García, M Martínez Pardo, A Belanger-Quintana, J L de la Mota, E Martin-Hernández, C Vianey-Saban, C Bischoff, N Gregersen, M Ugarte. Persistent increase of plasma butyryl/isobutyrylcarnitine concentrations as marker of SCAD defect and ethylmalonic encephalopathy. Journal of inherited metabolic disease. 2006 Oct; 29(5):685. doi: 10.1007/s10545-006-0342-8. [PMID: 16906473]
  • Bianca T van Maldegem, Marinus Duran, Ronald J A Wanders, Klary E Niezen-Koning, Marije Hogeveen, Lodewijk Ijlst, Hans R Waterham, Frits A Wijburg. Clinical, biochemical, and genetic heterogeneity in short-chain acyl-coenzyme A dehydrogenase deficiency. JAMA. 2006 Aug; 296(8):943-52. doi: 10.1001/jama.296.8.943. [PMID: 16926354]
  • Alexandra Hack, Verena Busch, Bettina Pascher, Raymonde Busch, Iris Bieger, Klaus Gempel, Friedrich A M Baumeister. Monitoring of ketogenic diet for carnitine metabolites by subcutaneous microdialysis. Pediatric research. 2006 Jul; 60(1):93-6. doi: 10.1203/01.pdr.0000219479.95410.79. [PMID: 16690958]
  • D S Roe, B Z Yang, C Vianey-Saban, E Struys, L Sweetman, C R Roe. Differentiation of long-chain fatty acid oxidation disorders using alternative precursors and acylcarnitine profiling in fibroblasts. Molecular genetics and metabolism. 2006 Jan; 87(1):40-7. doi: 10.1016/j.ymgme.2005.09.018. [PMID: 16297647]
  • Thomas J Conlon, Glenn Walter, Renius Owen, Travis Cossette, Kirsten Erger, Greg Gutierrez, Eric Goetzman, Dietrich Matern, Jerry Vockley, Terence R Flotte. Systemic correction of a fatty acid oxidation defect by intramuscular injection of a recombinant adeno-associated virus vector. Human gene therapy. 2006 Jan; 17(1):71-80. doi: 10.1089/hum.2006.17.71. [PMID: 16409126]
  • Judit Bene, Katalin Komlósi, Beáta Gasztonyi, Márk Juhász, Zsolt Tulassay, Béla Melegh. Plasma carnitine ester profile in adult celiac disease patients maintained on long-term gluten free diet. World journal of gastroenterology. 2005 Nov; 11(42):6671-5. doi: 10.3748/wjg.v11.i42.6671. [PMID: 16425363]
  • Brian Turpin, Joseph D Tobias. Perioperative management of a child with short-chain acyl-CoA dehydrogenase deficiency. Paediatric anaesthesia. 2005 Sep; 15(9):771-7. doi: 10.1111/j.1460-9592.2005.01507.x. [PMID: 16101709]
  • Neil Gordon. Acyl-CoA dehydrogenase deficiency: varieties with neurological involvement. Developmental medicine and child neurology. 2005 Mar; 47(3):207-10. doi: 10.1017/s0012162205000381. [PMID: 15739728]
  • Sarah P Young, Dietrich Matern, Niels Gregersen, Robert D Stevens, Deeksha Bali, Hui-Ming Liu, Dwight D Koeberl, David S Millington. A comparison of in vitro acylcarnitine profiling methods for the diagnosis of classical and variant short chain acyl-CoA dehydrogenase deficiency. Clinica chimica acta; international journal of clinical chemistry. 2003 Nov; 337(1-2):103-13. doi: 10.1016/j.cccn.2003.07.006. [PMID: 14568186]
  • Dwight D Koeberl, Sarah P Young, Niels S Gregersen, Jerry Vockley, Wendy E Smith, Daniel Kelly Benjamin, Yan An, Susan D Weavil, Shu H Chaing, Deeksha Bali, Marie T McDonald, Priya S Kishnani, Y-T Chen, David S Millington. Rare disorders of metabolism with elevated butyryl- and isobutyryl-carnitine detected by tandem mass spectrometry newborn screening. Pediatric research. 2003 Aug; 54(2):219-23. doi: 10.1203/01.pdr.0000074972.36356.89. [PMID: 12736383]
  • T Fukao, G X Zhang, N Sakura, T Kubo, H Yamaga, A Hazama, Y Kohno, N Matsuo, M Kondo, S Yamaguchi, Y Shigematsu, N Kondo. The mitochondrial acetoacetyl-CoA thiolase (T2) deficiency in Japanese patients: urinary organic acid and blood acylcarnitine profiles under stable conditions have subtle abnormalities in T2-deficient patients with some residual T2 activity. Journal of inherited metabolic disease. 2003; 26(5):423-31. doi: 10.1023/a:1025117226051. [PMID: 14518824]
  • J Seidel, S Streck, K Bellstedt, C Vianey-Saban, C B Pedersen, J Vockley, H Korall, M Roskos, T Deufel, K F Trefz, A C Sewell, E Kauf, F Zintl, W Lehnert, N Gregersen. Recurrent vomiting and ethylmalonic aciduria associated with rare mutations of the short-chain acyl-CoA dehydrogenase gene. Journal of inherited metabolic disease. 2003; 26(1):37-42. doi: 10.1023/a:1024019311933. [PMID: 12872838]