(24S)-7alpha,12alpha,24-trihydroxycholest-4-en-3-one (BioDeep_00001041038)
代谢物信息卡片
化学式: C27H44O4 (432.3239)
中文名称:
谱图信息:
最多检出来源 not specific(blood) 37.5%
分子结构信息
SMILES: CC(C)C(CCC(C)C1CCC2C1(C(CC3C2C(CC4=CC(=O)CCC34C)O)O)C)O
InChI: InChI=1S/C27H44O4/c1-15(2)22(29)9-6-16(3)19-7-8-20-25-21(14-24(31)27(19,20)5)26(4)11-10-18(28)12-17(26)13-23(25)30/h12,15-16,19-25,29-31H,6-11,13-14H2,1-5H3/t16-,19-,20+,21+,22+,23-,24+,25+,26+,27-/m1/s1
描述信息
7alpha,12alpha,24-trihydroxycholest-4-en-3-one with S-configuration at C-24.
同义名列表
相关代谢途径
Reactome(11)
- Metabolism
- Biological oxidations
- Phase I - Functionalization of compounds
- Metabolism of lipids
- Metabolism of steroids
- Cytochrome P450 - arranged by substrate type
- Bile acid and bile salt metabolism
- Synthesis of bile acids and bile salts
- Endogenous sterols
- Sterols are 12-hydroxylated by CYP8B1
- Synthesis of bile acids and bile salts via 24-hydroxycholesterol
BioCyc(0)
PlantCyc(0)
代谢反应
26 个相关的代谢反应过程信息。
Reactome(26)
- Metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Metabolism of lipids:
H+ + LTHSOL + Oxygen + TPNH ⟶ 7-dehydroCHOL + H2O + TPN - Metabolism of steroids:
H+ + LTHSOL + Oxygen + TPNH ⟶ 7-dehydroCHOL + H2O + TPN - Bile acid and bile salt metabolism:
CHOL + H+ + Oxygen + TPNH ⟶ 24OH-CHOL + H2O + TPN - Synthesis of bile acids and bile salts:
CHOL + H+ + Oxygen + TPNH ⟶ 24OH-CHOL + H2O + TPN - Synthesis of bile acids and bile salts via 24-hydroxycholesterol:
CHOL + H+ + Oxygen + TPNH ⟶ 24OH-CHOL + H2O + TPN - Sterols are 12-hydroxylated by CYP8B1:
4CHOL7aOLONE + H+ + Oxygen + TPNH ⟶ 4CHOL7a,12aDONE + H2O + TPN - Sterols are 12-hydroxylated by CYP8B1:
4CHOL7aOLONE + H+ + Oxygen + TPNH ⟶ 4CHOL7a,12aDONE + H2O + TPN - Metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Metabolism of lipids:
H+ + LTHSOL + Oxygen + TPNH ⟶ 7-dehydroCHOL + H2O + TPN - Metabolism of steroids:
H+ + LTHSOL + Oxygen + TPNH ⟶ 7-dehydroCHOL + H2O + TPN - Bile acid and bile salt metabolism:
CHOL + H+ + Oxygen + TPNH ⟶ 24OH-CHOL + H2O + TPN - Synthesis of bile acids and bile salts:
CHOL + H+ + Oxygen + TPNH ⟶ 24OH-CHOL + H2O + TPN - Synthesis of bile acids and bile salts via 24-hydroxycholesterol:
CHOL + H+ + Oxygen + TPNH ⟶ 24OH-CHOL + H2O + TPN - Metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Metabolism of lipids:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Metabolism of steroids:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA - Bile acid and bile salt metabolism:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA - Synthesis of bile acids and bile salts:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA - Synthesis of bile acids and bile salts via 24-hydroxycholesterol:
ATP + CoA-SH + TetraHCA ⟶ 25(R) TetraHCA-CoA + AMP + H2O + PPi - Biological oxidations:
H+ + Oxygen + TPNH + aflatoxin B1 ⟶ AFXBO + H2O + TPN - Phase I - Functionalization of compounds:
H+ + Oxygen + TPNH + aflatoxin B1 ⟶ AFXBO + H2O + TPN - Cytochrome P450 - arranged by substrate type:
H+ + Oxygen + TPNH + aflatoxin B1 ⟶ AFXBO + H2O + TPN - Endogenous sterols:
EST17b + H+ + Oxygen + TPNH ⟶ 4OH-EST17b + H2O + TPN - Sterols are 12-hydroxylated by CYP8B1:
4CHOL7aOLONE + H+ + Oxygen + TPNH ⟶ 4CHOL7a,12aDONE + H2O + TPN - Synthesis of bile acids and bile salts via 24-hydroxycholesterol:
4CHOL7a,12a,24(S)TONE + H+ + TPNH ⟶ 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one + TPN
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
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