flidersiachromone (BioDeep_00000001038)

 

Secondary id: BioDeep_00000868534

PANOMIX_OTCML-2023 Volatile Flavor Compounds


代谢物信息卡片


4H-1-Benzopyran-4-one, 2-(2-phenylethyl)-

化学式: C17H14O2 (250.09937440000002)
中文名称: 2-(2-苯乙基)色酮, 2-（2-苯乙基）色酮
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 12.07%

分子结构信息

SMILES: C1=CC=C(C=C1)CCC2=CC(=O)C3=CC=CC=C3O2
InChI: InChI=1S/C17H14O2/c18-16-12-14(11-10-13-6-2-1-3-7-13)19-17-9-5-4-8-15(16)17/h1-9,12H,10-11H2

描述信息

2-(2-phenylethyl)chromone is a member of the class of chromones that is chromone which is substituted by a 2-phenylethyl group at position 2. It is found in agarwood, a fragrant resinous heartwood obtained from certain trees in the genus Aquilaria. It has a role as a plant metabolite. It is a member of chromones and a member of benzenes. It is functionally related to a chromone.
2-(2-Phenylethyl)chromone is a natural product found in Aquilaria sinensis, Aquilaria malaccensis, and Imperata cylindrica with data available.
A member of the class of chromones that is chromone which is substituted by a 2-phenylethyl group at position 2. It is found in agarwood, a fragrant resinous heartwood obtained from certain trees in the genus Aquilaria.
2-(2-Phenylethyl)chromone (Flidersiachromone) is one of 2-(2-phenylethyl)chromones that can be found in Chinese eaglewood from Aquilaria sinensis[1].
2-(2-Phenylethyl)chromone (Flidersiachromone) is one of 2-(2-phenylethyl)chromones that can be found in Chinese eaglewood from Aquilaria sinensis[1].

同义名列表

15 个代谢物同义名

4H-1-Benzopyran-4-one, 2-(2-phenylethyl)-; 2-(2-phenylethyl)-4H-1-benzopyran-4-one; 2-phenylethyl-4H-1-benzopyran-4-one; 2-(2-phenylethyl)-4H-chromen-4-one; 2-(2-phenylethyl)chromen-4-one; 2-Phenethyl-4H-chromen-4-one; Chromone, 2-(2-phenylethyl); 2-(2-Phenylethyl) chromone; 2-(2-Phenylethyl)chromone; 2-phenethylchromen-4-one; 2-PHENETHYLCHROMONE; Flindersiachromone; flidersiachromone; Flindersiachromone; 2-(2-Phenylethyl)chromone



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Hong-Run Yang, Hao Wang, Pei Wang, Fang-Zheng Liu, Hong-Xing Chai, Cai-Hong Cai, Li Yang, Jing-Zhe Yuan, Bei Jiang, Wen-Li Mei, Hao-Fu Dai. Bi-2-(2-phenethyl)chromone derivatives from agarwood of Aquilaria filaria in the Philippines. Phytochemistry. 2024 Jun; 222(?):114108. doi: 10.1016/j.phytochem.2024.114108. [PMID: 38663825]
  • Jiale Ma, Lingxiao Wang, Yimu Zhao, Yun Gao, Ziyu Yin, Maoyuan Zhao, Yunfang Zhao, Xueping Pang, Junjiao Wang, Weigang Xue, Pengfei Tu, Jun Li, Jiao Zheng. 2-(2-Phenylethyl)chromone-enriched extract of Chinese agarwood (Aquilaria sinensis) inhibits atherosclerosis progression through endoplasmic reticulum stress-mediated CD36 expression in macrophages. Journal of ethnopharmacology. 2024 Feb; 320(?):117411. doi: 10.1016/j.jep.2023.117411. [PMID: 37956912]
  • Bin Hu, Shu-Jing Ling, Xia Liu, Jia-Bo Huang, Hui Cui, Zhong-Xiang Zhao. Two new 2-(2-phenylethyl)chromone derivatives and two sesquiterpenes from agarwood of Aquilaria sinensis with anti-inflammatory activity. Fitoterapia. 2024 Jan; 173(?):105824. doi: 10.1016/j.fitote.2024.105824. [PMID: 38244895]
  • Zhen Du, Huanjun Wang, Xueling Li, Meiyue Dong, Bingqing Chi, Zhenhua Tian, Zhenguo Wang, Haiqiang Jiang. Rapid screening and characterization of 2-(2-phenylethyl)chromones in agarwood by UHPLC-Q-Exactive Orbitrap-MS. Food chemistry. 2023 Oct; 424(?):136400. doi: 10.1016/j.foodchem.2023.136400. [PMID: 37236079]
  • Hiroyuki Morita, Yuan-E Lee, She-Po Shi. Identification of a diarylpentanoid-producing polyketide synthase in the biosynthesis of 2-(2-phenylethyl)chromones in agarwood. Journal of natural medicines. 2023 Sep; 77(4):667-676. doi: 10.1007/s11418-023-01743-5. [PMID: 37597060]
  • Yan Yang, Jiahong Zhu, Hao Wang, Dong Guo, Ying Wang, Wenli Mei, Shiqing Peng, Haofu Dai. Systematic investigation of the R2R3-MYB gene family in Aquilaria sinensis reveals a transcriptional repressor AsMYB054 involved in 2-(2-phenylethyl)chromone biosynthesis. International journal of biological macromolecules. 2023 Jun; 244(?):125302. doi: 10.1016/j.ijbiomac.2023.125302. [PMID: 37315664]
  • Yingxia Wang, Wenqian Huang, Weisheng Tian, Ting Mo, Yaru Yan, Xiaoxue Cui, Xiao Liu. Enzymatic biosynthesis of novel 2-(2-phenylethyl)chromone glycosides catalyzed by UDP-glycosyltransferase UGT71BD1. Biochemical and biophysical research communications. 2023 Jun; 671(?):80-86. doi: 10.1016/j.bbrc.2023.05.128. [PMID: 37300944]
  • Hang Zhang, Jia-Le Ma, Chuang Chang, He Ta, Yun-Fang Zhao, She-Po Shi, Yue-Lin Song, Peng-Fei Tu, Hui-Xia Huo, Jiao Zheng, Jun Li. Gastroprotective 2-(2-phenylethyl)chromone-sesquiterpene hybrids from the resinous wood of Aquilaria sinensis (Lour.) Gilg. Bioorganic chemistry. 2023 Jan; 133(?):106396. doi: 10.1016/j.bioorg.2023.106396. [PMID: 36758274]
  • Meng Yu, Qing-Qin He, Xi-Qin Chen, Jian Feng, Jian-He Wie, Yang-Yang Liu. Chemical and Bioactivity Diversity of 2-(2-Phenylethyl)chromones in Agarwood: A Review. Chemistry & biodiversity. 2022 Dec; 19(12):e202200490. doi: 10.1002/cbdv.202200490. [PMID: 36266258]
  • Xiao-Hui Wang, Bo-Wen Gao, Yu Nakashima, Takahiro Mori, Zhong-Xiu Zhang, Takeshi Kodama, Yuan-E Lee, Ze-Kun Zhang, Chin-Piow Wong, Qian-Qian Liu, Bo-Wen Qi, Juan Wang, Jun Li, Xiao Liu, Ikuro Abe, Hiroyuki Morita, Peng-Fei Tu, She-Po Shi. Identification of a diarylpentanoid-producing polyketide synthase revealing an unusual biosynthetic pathway of 2-(2-phenylethyl)chromones in agarwood. Nature communications. 2022 01; 13(1):348. doi: 10.1038/s41467-022-27971-z. [PMID: 35039506]
  • Wen-Yi Kao, Chien-Yun Hsiang, Shih-Ching Ho, Tin-Yun Ho, Kung-Ta Lee. Novel serotonin-boosting effect of incense smoke from Kynam agarwood in mice: The involvement of multiple neuroactive pathways. Journal of ethnopharmacology. 2021 Jul; 275(?):114069. doi: 10.1016/j.jep.2021.114069. [PMID: 33794334]
  • Mei Gao, Xiaomin Han, Junqing Huang, Ying Sun, Yangyang Liu, Hongjiang Chen, Yue Jin, Yun Yang, Zhihui Gao, Yanhong Xu, Zheng Zhang, Chunnian He. Simultaneous determination of multiple active 2-(2-phenylethyl)chromone analogues in agarwood by HPLC, QAMS, and UPLC-MS. Phytochemical analysis : PCA. 2021 May; 32(3):412-422. doi: 10.1002/pca.2989. [PMID: 32939882]
  • Chun-Ge Li, Li Pan, Zhu-Zhen Han, Yan-Qiao Xie, Hai-Jun Hu, Xiao-Long Liu, Li-Hong Wu, Li Yang, Zheng-Tao Wang. Antioxidative 2-(2-phenylethyl)chromones in Chinese eaglewood from Aquilaria sinensis. Journal of Asian natural products research. 2020 Jul; 22(7):639-646. doi: 10.1080/10286020.2019.1607841. [PMID: 31056992]
  • Yang-Yang Liu, De-Li Chen, Zhang-Xin Yu, Wang Can-Hong, Jian Feng, Yu Meng, Jian-He Wei. New 2-(2-phenylethyl)chromone derivatives from agarwood and their inhibitory effects on tumor cells. Natural product research. 2020 Jun; 34(12):1721-1727. doi: 10.1080/14786419.2018.1528591. [PMID: 30580631]
  • Shunsuke Shibata, Takuji Sugiyama, Yoshinori Uekusa, Ryo Masui, Yuji Narukawa, Fumiyuki Kiuchi. Five new 2-(2-phenylethyl)chromone derivatives from agarwood. Journal of natural medicines. 2020 Jun; 74(3):561-570. doi: 10.1007/s11418-020-01410-z. [PMID: 32335822]
  • Ge Liao, Wen-Hua Dong, Jin-Ling Yang, Wei Li, Jun Wang, Wen-Li Mei, Hao-Fu Dai. Monitoring the Chemical Profile in Agarwood Formation within One Year and Speculating on the Biosynthesis of 2-(2-Phenylethyl)Chromones. Molecules (Basel, Switzerland). 2018 May; 23(6):. doi: 10.3390/molecules23061261. [PMID: 29799457]
  • Xiaohui Wang, Xianjuan Dong, Yingying Feng, Xiao Liu, Jinling Wang, Zhongxiu Zhang, Jun Li, Yunfang Zhao, Shepo Shi, Pengfei Tu. H2O2 and NADPH oxidases involve in regulation of 2-(2-phenylethyl)chromones accumulation during salt stress in Aquilaria sinensis calli. Plant science : an international journal of experimental plant biology. 2018 Apr; 269(?):1-11. doi: 10.1016/j.plantsci.2018.01.002. [PMID: 29606206]
  • Hui-Xia Huo, Zhi-Xiang Zhu, Yue-Lin Song, She-Po Shi, Jing Sun, Hui Sun, Yun-Fang Zhao, Jiao Zheng, Daneel Ferreira, Jordan K Zjawiony, Peng-Fei Tu, Jun Li. Anti-inflammatory Dimeric 2-(2-Phenylethyl)chromones from the Resinous Wood of Aquilaria sinensis. Journal of natural products. 2018 03; 81(3):543-553. doi: 10.1021/acs.jnatprod.7b00919. [PMID: 29227647]
  • Hui-Xia Huo, Yu-Fan Gu, Hui Sun, Yun-Feng Zhang, Wen-Jing Liu, Zhi-Xiang Zhu, She-Po Shi, Yue-Lin Song, Hong-Wei Jin, Yun-Fang Zhao, Peng-Fei Tu, Jun Li. Anti-inflammatory 2-(2-phenylethyl)chromone derivatives from Chinese agarwood. Fitoterapia. 2017 Apr; 118(?):49-55. doi: 10.1016/j.fitote.2017.02.009. [PMID: 28237880]
  • Airi Suzuki, Katsunori Miyake, Yohei Saito, Faradiba Abdul Rasyid, Harukuni Tokuda, Misa Takeuchi, Nobutaka Suzuki, Eiichiro Ichiishi, Tetsuo Fujie, Masuo Goto, Yohei Sasaki, Kyoko Nakagawa-Goto. Phenylethylchromones with In Vitro Antitumor Promoting Activity from Aquilaria filaria. Planta medica. 2017 Feb; 83(3-04):300-305. doi: 10.1055/s-0042-110858. [PMID: 27392244]
  • Hang Shao, Wen-Li Mei, Wen-Hua Dong, Cui-Juan Gai, Wei Li, Guo-Peng Zhu, Hao-Fu Dai. 2-(2-Phenylethyl)chromone Derivatives of Agarwood Originating from Gyrinops salicifolia. Molecules (Basel, Switzerland). 2016 Oct; 21(10):. doi: 10.3390/molecules21101313. [PMID: 27706109]
  • Takuji Sugiyama, Yuji Narukawa, Shunsuke Shibata, Ryo Masui, Fumiyuki Kiuchia. New 2-(2-Phenylethyl)chromone Derivatives and Inhibitors of Phosphodiesterase (PDE) 3A from Agarwood. Natural product communications. 2016 Jun; 11(6):795-7. doi: . [PMID: 27534119]
  • Yuanbin Li, Nan Sheng, Lingli Wang, Shijie Li, Jiannan Chen, Xiaoping Lai. Analysis of 2-(2-Phenylethyl)chromones by UPLC-ESI-QTOF-MS and Multivariate Statistical Methods in Wild and Cultivated Agarwood. International journal of molecular sciences. 2016 May; 17(5):. doi: 10.3390/ijms17050771. [PMID: 27223280]
  • Ge Liao, Wen-Li Mei, Wen-Hua Dong, Wei Li, Pei Wang, Fan-Dong Kong, Cui-Juan Gai, Xi-Qiang Song, Hao-Fu Dai. 2-(2-Phenylethyl)chromone derivatives in artificial agarwood from Aquilaria sinensis. Fitoterapia. 2016 Apr; 110(?):38-43. doi: 10.1016/j.fitote.2016.01.011. [PMID: 26784520]
  • Sabrin R M Ibrahim, Gamal A Mohamed. Natural occurring 2-(2-phenylethyl) chromones, structure elucidation and biological activities. Natural product research. 2015; 29(16):1489-520. doi: 10.1080/14786419.2014.991323. [PMID: 25529202]
  • Jun Li, Dong Chen, Yong Jiang, Qian Zhang, Liang Zhang, Peng-Fei Tu. Identification and quantification of 5,6,7,8-tetrahydro-2-(2-phenylethyl)chromones in Chinese eaglewood by HPLC with diode array detection and MS. Journal of separation science. 2013 Dec; 36(23):3733-40. doi: 10.1002/jssc.201300687. [PMID: 24115601]
  • Wen-Li Mei, De-Lan Yang, Hao Wang, Jin-Ling Yang, Yan-Bo Zeng, Zhi-Kai Guo, Wen-Hua Dong, Wei Li, Hao-Fu Dai. Characterization and determination of 2-(2-phenylethyl)chromones in agarwood by GC-MS. Molecules (Basel, Switzerland). 2013 Oct; 18(10):12324-45. doi: 10.3390/molecules181012324. [PMID: 24108398]
  • Lin Yang, Lirui Qiao, Dan Xie, Yuhe Yuan, Naihong Chen, Jungui Dai, Shunxing Guo. 2-(2-phenylethyl)chromones from Chinese eaglewood. Phytochemistry. 2012 Apr; 76(?):92-7. doi: 10.1016/j.phytochem.2011.11.017. [PMID: 22243963]
  • Sabrin R M Ibrahim. New 2-(2-phenylethyl)chromone derivatives from the seeds of Cucumis melo L var. reticulatus. Natural product communications. 2010 Mar; 5(3):403-6. doi: ". [PMID: 20420317]
  • J S Yang, Y L Wang, Y L Su. [Studies on the chemical constituents of Aquilaria sinensis(Lour.) Gilg. IV. Isolation and characterization of 2-(2-phenylethyl)chromone derivatives]. Yao xue xue bao = Acta pharmaceutica Sinica. 1989; 24(9):678-83. doi: . [PMID: 2618717]
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