Asn-Gly-Arg (BioDeep_00001036227)
代谢物信息卡片
化学式: C12H23N7O5 (345.1761)
中文名称:
谱图信息:
最多检出来源 () %
分子结构信息
SMILES: C(CC(C(=O)O)NC(=O)CNC(=O)C(CC(=O)N)N)CN=C(N)N
InChI: InChI=1S/C12H23N7O5/c13-6(4-8(14)20)10(22)18-5-9(21)19-7(11(23)24)2-1-3-17-12(15)16/h6-7H,1-5,13H2,(H2,14,20)(H,18,22)(H,19,21)(H,23,24)(H4,15,16,17)/t6-,7-/m0/s1
相关代谢途径
Reactome()
BioCyc()
PlantCyc()
代谢反应
个相关的代谢反应过程信息。
Reactome()
BioCyc()
WikiPathways()
Plant Reactome()
INOH()
PlantCyc()
COVID-19 Disease Map()
PathBank()
PharmGKB()
个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
- Andrea Angelo Pierluigi Tripodi, Ivan Ranđelović, Beáta Biri-Kovács, Bálint Szeder, Gábor Mező, József Tóvári. In Vivo Tumor Growth Inhibition and Antiangiogenic Effect of Cyclic NGR Peptide-Daunorubicin Conjugates Developed for Targeted Drug Delivery.
Pathology oncology research : POR.
2020 Jul; 26(3):1879-1892. doi:
10.1007/s12253-019-00773-3
. [PMID: 31820302] - Xue Zheng, Chao Sun, Rilei Yu, Xin Chu, Jiahao Xu, Chengcheng Liu, Miaoqing Zhao, Xuelian Xu, Ming Xia, Cheng Wang. CD13-specific ligand facilitates Xanthatin nanomedicine targeting dendritic cells for therapy of refractory allergic rhinitis.
International journal of pharmaceutics.
2020 Mar; 577(?):119034. doi:
10.1016/j.ijpharm.2020.119034
. [PMID: 31991183] - Xin-Jun Cai, Wei-Dong Fei, Ying-Ying Xu, Hong Xu, Gao-Yi Yang, Jia-Wei Cao, Jian-Jun Ni, Zeng Wang. Combination of metronomic administration and target delivery strategies to improve the anti-angiogenic and anti-tumor effects of triptolide.
Drug delivery and translational research.
2020 02; 10(1):93-107. doi:
10.1007/s13346-019-00665-8
. [PMID: 31418132] - Shiyao Fu, Meng Liang, Yuli Wang, Lin Cui, Chunhong Gao, Xiaoyang Chu, Qianqian Liu, Ye Feng, Wei Gong, Meiyan Yang, Zhiping Li, Chunrong Yang, Xiangyang Xie, Yang Yang, Chunsheng Gao. Dual-Modified Novel Biomimetic Nanocarriers Improve Targeting and Therapeutic Efficacy in Glioma.
ACS applied materials & interfaces.
2019 Jan; 11(2):1841-1854. doi:
10.1021/acsami.8b18664
. [PMID: 30582685] - Jun Chen, Aihua Lin, Pei Peng, Yong Wang, Wei Gu, Yiming Liu. Lipid composition has significant effect on targeted drug delivery properties of NGR-modified liposomes.
Drug delivery.
2016 May; 23(4):1426-33. doi:
10.3109/10717544.2015.1088598
. [PMID: 26373704] - Zhe Zhang, Lei Hou, Lu Feng, Shangke Huang, Minna Luo, Shan Shao, Xiaojin Zhang, Shanzhi Gu, Xinhan Zhao. An antimicrobial peptide containing NGR motif has potent antitumor activity against CD13+ and CD13- tumor cells.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.
2015 Sep; 36(10):8167-75. doi:
10.1007/s13277-015-3402-6
. [PMID: 25990455] - Yanfang Yang, Xiangyang Xie, Yang Yang, Hui Zhang, Xingguo Mei. Photo-responsive and NGR-mediated multifunctional nanostructured lipid carrier for tumor-specific therapy.
Journal of pharmaceutical sciences.
2015 Apr; 104(4):1328-39. doi:
10.1002/jps.24333
. [PMID: 25630979] - Yanfang Yang, Yang Yang, Xiangyang Xie, Xingshi Cai, Hui Zhang, Wei Gong, Zhiyuan Wang, Xingguo Mei. PEGylated liposomes with NGR ligand and heat-activable cell-penetrating peptide-doxorubicin conjugate for tumor-specific therapy.
Biomaterials.
2014 May; 35(14):4368-81. doi:
10.1016/j.biomaterials.2014.01.076
. [PMID: 24565519] - Jun Zhang, Xiaoli Lu, Nan Wan, Zichun Hua, Zizheng Wang, Hongbo Huang, Min Yang, Feng Wang. 68Ga-DOTA-NGR as a novel molecular probe for APN-positive tumor imaging using MicroPET.
Nuclear medicine and biology.
2014 Mar; 41(3):268-75. doi:
10.1016/j.nucmedbio.2013.12.008
. [PMID: 24438818] - Xue-Xi Wang, Li Lu, Chun-Li Song, Wei-Na Qian, Sheng-Yan Zhang, Ying-Qi Zhang, Yong-Jie Wu. Comparative pharmacokinetics of a tumour-targeting therapy candidate rh-IFNα2a-NGR with rh-IFNα2a administered intravenously in mice and rats.
The Journal of pharmacy and pharmacology.
2013 Apr; 65(4):574-81. doi:
10.1111/jphp.12022
. [PMID: 23488787] - Kazuhiro Takara, Hiroto Hatakeyama, Golam Kibria, Noritaka Ohga, Kyoko Hida, Hideyoshi Harashima. Size-controlled, dual-ligand modified liposomes that target the tumor vasculature show promise for use in drug-resistant cancer therapy.
Journal of controlled release : official journal of the Controlled Release Society.
2012 Aug; 162(1):225-32. doi:
10.1016/j.jconrel.2012.06.019
. [PMID: 22728515] - Jin Wang, Zhen-zhong Zhang, Tian-yang Zhou, Yu-qiong Liu, Hui-xiang Li. [Effect of nanosize delivery system for ASODN against hTERT on the expression of telomerase in the esophageal cancer EC9706 cells].
Zhonghua zhong liu za zhi [Chinese journal of oncology].
2008 Aug; 30(8):566-72. doi:
NULL
. [PMID: 19102931]