2-methyl-1,1,4-trioxo-N-(2-pyridinyl)-3H-thieno[2,3-e]thiazine-3-carboxamide (BioDeep_00001034660)
代谢物信息卡片
化学式: C13H11N3O4S2 (337.0190966)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CN1C(C(=O)C2=C(S1(=O)=O)C=CS2)C(=O)NC3=CC=CC=N3
InChI: InChI=1S/C13H11N3O4S2/c1-16-10(13(18)15-9-4-2-3-6-14-9)11(17)12-8(5-7-21-12)22(16,19)20/h2-7,10H,1H3,(H,14,15,18)
相关代谢途径
Reactome(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Jean-Pascal Fournier, Maryse Lapeyre-Mestre, Agnès Sommet, Julie Dupouy, Jean-Christophe Poutrain, Jean-Louis Montastruc. Laboratory monitoring of patients treated with antihypertensive drugs and newly exposed to non steroidal anti-inflammatory drugs: a cohort study.
PloS one.
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Mediators of inflammation.
2012; 2012(?):438912. doi:
10.1155/2012/438912
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Langmuir : the ACS journal of surfaces and colloids.
2011 Dec; 27(24):15054-64. doi:
10.1021/la2030186
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The journal of physical chemistry. B.
2011 Jul; 115(29):9290-8. doi:
10.1021/jp202716k
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Sensors (Basel, Switzerland).
2011; 11(9):8813-25. doi:
10.3390/s110908813
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Journal of lipids.
2011; 2011(?):528784. doi:
10.1155/2011/528784
. [PMID: 21660306] - Sutapa Mondal Roy, Amol S Bansode, Munna Sarkar. Effect of increase in orientational order of lipid chains and head group spacing on non steroidal anti-inflammatory drug induced membrane fusion.
Langmuir : the ACS journal of surfaces and colloids.
2010 Dec; 26(24):18967-75. doi:
10.1021/la103802d
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The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology.
2010 Jun; 21(2):146-52. doi:
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. [PMID: 20872328] - Katarzyna Czapla, Beata Korchowiec, Ewa Rogalska. Differentiating oxicam nonsteroidal anti-inflammatory drugs in phosphoglyceride monolayers.
Langmuir : the ACS journal of surfaces and colloids.
2010 Mar; 26(5):3485-92. doi:
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. [PMID: 20030324] - Marcelo Soares Privado, Adriana Machado Issy, Vera Lucia Lanchote, João Batista Santos Garcia, Rioko Kimiko Sakata. Epidural versus intravenous fentanyl for postoperative analgesia following orthopedic surgery: randomized controlled trial.
Sao Paulo medical journal = Revista paulista de medicina.
2010 Jan; 128(1):5-9. doi:
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The journal of physical chemistry. B.
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Colloids and surfaces. B, Biointerfaces.
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Drug discoveries & therapeutics.
2009 Feb; 3(1):27-36. doi:
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International urology and nephrology.
2009; 41(3):541-5. doi:
10.1007/s11255-008-9517-6
. [PMID: 19165617] - Haixia Zhang, Hoo-Kyun Choi. Analysis of meloxicam by high-performance liquid chromatography with cloud-point extraction.
Analytical and bioanalytical chemistry.
2008 Nov; 392(5):947-53. doi:
10.1007/s00216-008-2333-0
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Biophysical chemistry.
2008 Sep; 137(1):28-34. doi:
10.1016/j.bpc.2008.06.007
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Neurochemical research.
2008 Sep; 33(9):1832-7. doi:
10.1007/s11064-008-9643-7
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Scandinavian journal of urology and nephrology.
2008; 42(2):143-7. doi:
10.1080/00365590701225988
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The Journal of pharmacy and pharmacology.
2008 Jan; 60(1):135-8. doi:
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. [PMID: 18088513] - J Grifka. [Use of drugs in renal impairment].
Der Internist.
2008 Jan; 49(1):126. doi:
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. [PMID: 18210021] - Iulia Sora, Toma Galaon, Stefan Udrescu, Jean Negru, Victor David, Andrei Medvedovici. Fast RPLC-UV method on short sub-two microns particles packed column for the assay of tenoxicam in plasma samples.
Journal of pharmaceutical and biomedical analysis.
2007 Mar; 43(4):1437-43. doi:
10.1016/j.jpba.2006.11.008
. [PMID: 17142002] - H Modesto Rigato, G Duarte Mendes, N Carter do Carmo Borges, R A Moreno. Meloxicam determination in human plasma by high-performance liquid chromatography coupled with tandem mass spectrometry (LC-MS-MS) in Brazilian bioequivalence studies.
International journal of clinical pharmacology and therapeutics.
2006 Oct; 44(10):489-98. doi:
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. [PMID: 17063980] - M Lúcio, H Ferreira, José L F C Lima, Salette Reis. Interactions between oxicams and membrane bilayers: an explanation for their different COX selectivity.
Medicinal chemistry (Shariqah (United Arab Emirates)).
2006 Sep; 2(5):447-56. doi:
10.2174/157340606778250199
. [PMID: 17017983] - Hye Young Ji, Hye Won Lee, Young Hoon Kim, Dong Won Jeong, Hye Suk Lee. Simultaneous determination of piroxicam, meloxicam and tenoxicam in human plasma by liquid chromatography with tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2005 Nov; 826(1-2):214-9. doi:
10.1016/j.jchromb.2005.08.023
. [PMID: 16169293] - T Yamamoto, H Itoga, Y Kohno, K Nagata, Y Yamazoe. Prediction of oral clearance from in vitro metabolic data using recombinant CYPs: comparison among well-stirred, parallel-tube, distributed and dispersion models.
Xenobiotica; the fate of foreign compounds in biological systems.
2005 Jun; 35(6):627-46. doi:
10.1080/00498250500159371
. [PMID: 16192112] - I M M Paino, V F Ximenes, L M da Fonseca, M P P Kanegae, N M Khalil, I L Brunetti. Effect of therapeutic plasma concentrations of non-steroidal anti-inflammatory drugs on the production of reactive oxygen species by activated rat neutrophils.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.
2005 Apr; 38(4):543-51. doi:
10.1590/s0100-879x2005000400007
. [PMID: 15962179] - Hortense Priscilla, Renata Alessandra Evangelista, Fátima Aparecida Emm Faleiros Sousa. [Post-hemorrhoidectomy pain descriptors].
Revista latino-americana de enfermagem.
2005 Mar; 13(2):203-7. doi:
10.1590/s0104-11692005000200011
. [PMID: 15962065] - Salih Ozgocmen, Ozge Ardicoglu, Hasan Erdogan, Ersin Fadillioglu, Huseyin Gudul. In vivo effect of celecoxib and tenoxicam on oxidant/ anti-oxidant status of patients with knee osteoarthritis.
Annals of clinical and laboratory science.
2005; 35(2):137-43. doi:
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. [PMID: 15943176] - Mohamed Sultan, Günther Stecher, Wolfgang M Stöggl, Rania Bakry, P Zaborski, C W Huck, Nagla M El Kousy, Günther K Bonn. Sample pretreatment and determination of non steroidal anti-inflammatory drugs (NSAIDs) in pharmaceutical formulations and biological samples (blood, plasma, erythrocytes) by HPLC-UV-MS and micro-HPLC.
Current medicinal chemistry.
2005; 12(5):573-88. doi:
10.2174/0929867310504050573
. [PMID: 15777213] - Dilek Memiş, Beyhan Karamanlioğlu, Alparslan Turan, Onur Koyuncu, Zafer Pamukçu. Effects of lornoxicam on the physiology of severe sepsis.
Critical care (London, England).
2004 Dec; 8(6):R474-82. doi:
10.1186/cc2969
. [PMID: 15566594] - I Kyrikou, S K Hadjikakou, D Kovala-Demertzi, K Viras, T Mavromoustakos. Effects of non-steroid anti-inflammatory drugs in membrane bilayers.
Chemistry and physics of lipids.
2004 Dec; 132(2):157-69. doi:
10.1016/j.chemphyslip.2004.06.005
. [PMID: 15555602] - Tamer Akca, Tahsin Colak, Arzu Kanik, Faik Yaylak, Mehmet Caglikulekci, Suha Aydin. The effect of preoperative intravenous use of tenoxicam: a prospective, double-blind, placebo-controlled study.
Journal of investigative surgery : the official journal of the Academy of Surgical Research.
2004 Nov; 17(6):333-8. doi:
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. [PMID: 15764501] - Rosane Vianna-Jorge, Jamila A Perini, Edson Rondinelli, Guilherme Suarez-Kurtz. CYP2C9 genotypes and the pharmacokinetics of tenoxicam in Brazilians.
Clinical pharmacology and therapeutics.
2004 Jul; 76(1):18-26. doi:
10.1016/j.clpt.2004.03.002
. [PMID: 15229460] - Andrew R McKinney, Craig J Suann, Allen M Stenhouse. The detection of piroxicam, tenoxicam and their metabolites in equine urine by electrospray ionisation ion trap mass spectrometry.
Rapid communications in mass spectrometry : RCM.
2004; 18(19):2338-42. doi:
10.1002/rcm.1631
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British journal of cancer.
2003 Jun; 88(11):1687-92. doi:
10.1038/sj.bjc.6600945
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International journal of pharmaceutics.
2003 Apr; 256(1-2):95-107. doi:
10.1016/s0378-5173(03)00066-8
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Anaesthesia and intensive care.
2002 Apr; 30(2):160-6. doi:
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The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception.
2002 Mar; 7(1):36-40. doi:
10.1080/ejc.7.1.36.40
. [PMID: 12041863] - O G Nilsen, K Aasarød, T E Widerøe, T W Guentert. Single- and multiple-dose pharmacokinetics, kidney tolerability and plasma protein binding of tenoxicam in renally impaired patients and healthy volunteers.
Pharmacology & toxicology.
2001 Nov; 89(5):265-72. doi:
10.1034/j.1600-0773.2001.d01-158.x
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International journal of pharmaceutics.
2001 Jun; 221(1-2):227-9. doi:
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. [PMID: 11397584] - H Orhan, G Sahin. In vitro effects of NSAIDS and paracetamol on oxidative stress-related parameters of human erythrocytes.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.
2001 Jun; 53(2-3):133-40. doi:
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