beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-N-stearoylsphingosine (BioDeep_00001032643)
代谢物信息卡片
beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-N-stearoylsphingosine
化学式: C62H114N2O23 (1254.7811974)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCCCCCCCCCCCCC(=O)NC(COC1C(C(C(C(O1)CO)OC2C(C(C(C(O2)CO)OC3C(C(C(C(O3)CO)O)OC4C(C(C(C(O4)CO)O)O)O)NC(=O)C)O)O)O)O)C(C=CCCCCCCCCCCCCC)O
InChI: InChI=1S/C62H114N2O23/c1-4-6-8-10-12-14-16-18-19-21-23-25-27-29-31-33-46(71)64-40(41(70)32-30-28-26-24-22-20-17-15-13-11-9-7-5-2)38-80-60-54(78)51(75)57(44(36-67)83-60)86-62-55(79)52(76)56(45(37-68)84-62)85-59-47(63-39(3)69)58(49(73)43(35-66)81-59)87-61-53(77)50(74)48(72)42(34-65)82-61/h30,32,40-45,47-62,65-68,70,72-79H,4-29,31,33-38H2,1-3H3,(H,63,69)(H,64,71)/b32-30+/t40-,41+,42+,43+,44+,45+,47+,48-,49-,50-,51+,52+,53+,54+,55+,56-,57+,58+,59-,60+,61-,62-/m0/s1
描述信息
A beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer in which the ceramide N-acyl group is specified as stearoyl.
同义名列表
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
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Microbiology and immunology.
1994; 38(1):47-53. doi:
10.1111/j.1348-0421.1994.tb01743.x. [PMID: 7519717] - I Varani, A Terzaghi, L Donati, M Marazzi, M Masserini, G Tettamanti. Protective effect of some exogenous glycolipids on human cultured keratinocytes against lipid peroxidation.
Archives of dermatological research.
1994; 286(8):481-3. doi:
10.1007/bf00371576. [PMID: 7864663] - L D Hazlett, S Masinick, R Barrett, K Rosol. Evidence for asialo GM1 as a corneal glycolipid receptor for Pseudomonas aeruginosa adhesion.
Infection and immunity.
1993 Dec; 61(12):5164-73. doi:
10.1128/iai.61.12.5164-5173.1993. [PMID: 8225593] - K Vanderkerken, L Bouwens, W De Neve, K Van den Berg, M Baekeland, N Delens, E Wisse. Origin and differentiation of hepatic natural killer cells (pit cells).
Hepatology (Baltimore, Md.).
1993 Oct; 18(4):919-25. doi:
10.1002/hep.1840180425. [PMID: 8406368] - N Yuki, K Yanagisawa, Y Saito, M Aikawa, T Miyatake. [Proximal lower motor neuron syndrome associated with serum antibodies to asialo-GM1, GM1 and LM1].
Rinsho shinkeigaku = Clinical neurology.
1993 Aug; 33(8):891-4. doi:
NULL. [PMID: 8261703] - S Ikeda, J Neyts, M Matsuura, M Kiso, A Hasegawa, C Nishimura, E De Clercq. Protective activity of lipid A analogue GLA-60 against murine cytomegalovirus infection in mice.
Journal of medical virology.
1993 Jul; 40(3):222-7. doi:
10.1002/jmv.1890400310. [PMID: 8394873] - S N Cho, B J Gormus, K Xu, R P Bohm, G P Walsh, W M Meyers, J D Kim. Serologic responses to nerve antigens in sooty mangabey monkeys with experimental leprosy.
International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association.
1993 Jun; 61(2):236-44. doi:
NULL. [PMID: 8371033] - S Nonoyama, F O Smith, I D Bernstein, H D Ochs. Strain-dependent leakiness of mice with severe combined immune deficiency.
Journal of immunology (Baltimore, Md. : 1950).
1993 May; 150(9):3817-24. doi:
NULL. [PMID: 8473734] - E Sobotková, K Nouza. Regulatory role of T lymphocytes and NK cells in tumor allograft development.
Neoplasma.
1993; 40(2):75-80. doi:
NULL. [PMID: 8350958] - Y Eizuru, N Nakagawa, R Hamasuna, Y Minamishima. Protective effect of MDP-Lys(L18), a synthetic derivative of muramyldipeptide, on murine cytomegalovirus infection.
Natural immunity.
1992 Jul; 11(4):225-36. doi:
NULL. [PMID: 1384831] - A Chakrabarti, S K Podder. Complex carbohydrate-lectin interaction at the interface: a model for cellular adhesion. II. Reactivity of both the oligosaccharide chain and sugar-binding domain of a glycoprotein lectin.
Journal of molecular recognition : JMR.
1992 Jun; 5(2):69-73. doi:
10.1002/jmr.300050204. [PMID: 1472382] - A Bilge, S B Pollack. Regulation of natural killer cell production in bone marrow of mice: no evidence for negative feedback control.
Natural immunity.
1992 May; 11(3):156-66. doi:
NULL. [PMID: 1392403] - K Miyahara, T Matsumoto, S Tose, H Sakurai, I Igarashi, A Saito, T Hirose, N Suzuki. Characteristics of cytotoxic cells induced by Toxoplasma lysate antigen in mouse spleen.
The Journal of veterinary medical science.
1992 Feb; 54(1):87-93. doi:
10.1292/jvms.54.87. [PMID: 1558895] - Y Umesaki, H Setoyama. Immune responses of mice to orally administered asialo GM1-specific rabbit IgG in the presence or absence of cholera toxin.
Immunology.
1992 Feb; 75(2):386-8. doi:
NULL. [PMID: 1551702] - H Yoshino, T Inuzuka, T Miyatake. IgG antibody against GM1, GD1b and asialo-GM1 in chronic polyneuropathy following Mycoplasma pneumoniae infection.
European neurology.
1992; 32(1):28-31. doi:
10.1159/000116872. [PMID: 1563451] - D De Ruysscher, H Sobis, M Vandeputte, M Waer. A subset of asialo GM1+ cells play a protective role in the occurrence of graft-versus-host disease in mice.
Journal of immunology (Baltimore, Md. : 1950).
1991 Jun; 146(12):4065-70. doi:
NULL. [PMID: 1828259] - T Maruyama, K Watanabe, I Takei, A Kasuga, A Shimada, T Yanagawa, T Kasatani, Y Suzuki, K Kataoka, Saruta. Anti-asialo GM1 antibody suppression of cyclophosphamide-induced diabetes in NOD mice.
Diabetes research (Edinburgh, Scotland).
1991 May; 17(1):37-41. doi:
NULL. [PMID: 1823558] - S Tanji. [Effect of biological response modifiers on a spontaneous murine renal cell carcinoma regression of metastases caused by the streptococcal preparation OK-432].
Nihon Hinyokika Gakkai zasshi. The japanese journal of urology.
1991 May; 82(5):716-25. doi:
10.5980/jpnjurol1989.82.716. [PMID: 1875566] - H C Krivan, B Nilsson, C A Lingwood, H Ryu. Chlamydia trachomatis and Chlamydia pneumoniae bind specifically to phosphatidylethanolamine in HeLa cells and to GalNAc beta 1-4Gal beta 1-4GLC sequences-found in asialo-GM1 and asial-GM2.
Biochemical and biophysical research communications.
1991 Mar; 175(3):1082-9. doi:
10.1016/0006-291x(91)91676-4. [PMID: 2025240] - A A Ilyas, F A Mithen, Z W Chen, S D Cook. Search for antibodies to neutral glycolipids in sera of patients with Guillain-Barré syndrome.
Journal of the neurological sciences.
1991 Mar; 102(1):67-75. doi:
10.1016/0022-510x(91)90095-o. [PMID: 1856733] - P Rock, M Allietta, W W Young, T E Thompson, T W Tillack. Ganglioside GM1 and asialo-GM1 at low concentration are preferentially incorporated into the gel phase in two-component, two-phase phosphatidylcholine bilayers.
Biochemistry.
1991 Jan; 30(1):19-25. doi:
10.1021/bi00215a003. [PMID: 1988021] - P Rock, M Allietta, W W Young, T E Thompson, T W Tillack. Organization of glycosphingolipids in phosphatidylcholine bilayers: use of antibody molecules and Fab fragments as morphologic markers.
Biochemistry.
1990 Sep; 29(36):8484-90. doi:
10.1021/bi00488a040. [PMID: 2252906] - D K Wagner, H L Wong, M K Gately, D L Nelson. Cellular source of soluble interleukin 2 receptors in serum of mice after recombinant interleukin 2 administration.
Cytokine.
1990 Sep; 2(5):337-43. doi:
10.1016/1043-4666(90)90063-y. [PMID: 1715768] - F Suzuki, R B Pollard, S Uchimura, T Munakata, H Maeda. Role of natural killer cells and macrophages in the nonspecific resistance to tumors in mice stimulated with SMANCS, a polymer-conjugated derivative of neocarzinostatin.
Cancer research.
1990 Jul; 50(13):3897-904. doi:
NULL. [PMID: 2141295] - W Lauzon, H Yang, I Lemaire. Comparative analysis of natural killer function in lung, spleen, and peripheral blood lymphocytes: evidence of differential characteristics.
Regional immunology.
1990 199; 3(3):145-50. doi:
NULL. [PMID: 2129104] - Y Fujii, F Sendo, T Kamiyama, M Naiki. IgG antibodies to asialoGM1 are more sensitive than IgM antibodies to kill in vivo natural killer cells and prematured cytotoxic T lymphocytes of mouse spleen.
Microbiology and immunology.
1990; 34(6):533-42. doi:
NULL. [PMID: 2170825] - R Maekawa, T Kitagawa, K Koizumi, K Sato, M Homma. Distinct antitumor mechanisms of recombinant interleukin-2 on recombinant interleukin-2-activated killer-sensitive and -resistant murine tumors.
Journal of biological response modifiers.
1989 Dec; 8(6):676-90. doi:
NULL. [PMID: 2600605] - H Baba, G C Daune, A A Ilyas, A Pestronk, D R Cornblath, V Chaudhry, J W Griffin, R H Quarles. Anti-GM1 ganglioside antibodies with differing fine specificities in patients with multifocal motor neuropathy.
Journal of neuroimmunology.
1989 Dec; 25(2-3):143-50. doi:
10.1016/0165-5728(89)90131-8. [PMID: 2584393] - D M Marcus, L Perry, S Gilbert, J L Preud'homme, R Kyle. Human IgM monoclonal proteins that bind 3-fucosyllactosamine, asialo-GM1, and GM1.
Journal of immunology (Baltimore, Md. : 1950).
1989 Nov; 143(9):2929-32. doi:
NULL. [PMID: 2572647] - I Algarra, C Ohlén, M Perez, H G Ljunggren, G Klein, F Garrido, K Kärre. NK sensitivity and lung clearance of MHC-class-I-deficient cells within a heterogeneous fibrosarcoma.
International journal of cancer.
1989 Oct; 44(4):675-80. doi:
10.1002/ijc.2910440420. [PMID: 2507453] - A Punturieri, A Santoni, W J Ming, N Nobili, A Mantovani, B Bottazzi. In vitro migration of rat large granular lymphocytes.
Cellular immunology.
1989 Oct; 123(2):257-63. doi:
10.1016/0008-8749(89)90286-4. [PMID: 2790962] - G L Stewart, J Y Niederkorn, S Ghazizadeh, E Mayhew, E Ahanotu. A mechanism for anti-asialo GM 1 antibody-induced anaphylactoid response in mice infected with Trichinella pseudospiralis.
The Journal of parasitology.
1989 Oct; 75(5):780-6. doi:
10.2307/3283064. [PMID: 2795381] - T Shirahama, T Kayajima, Y Ohi. The antitumor effects of IFN- beta against human renal cell carcinoma in athymic nude mice.
In vivo (Athens, Greece).
1989 Sep; 3(5):345-9. doi:
NULL. [PMID: 2519876] - C Ryoyama, K Ryoyama. Effects of injection routes of growing tumors and PSK or OK-432 on antiproliferative activity of mouse serum.
Cancer immunology, immunotherapy : CII.
1989; 28(2):101-6. doi:
10.1007/bf00199109. [PMID: 2537148] - T D Anderson, T J Hayes, M K Gately, J M Bontempo, L L Stern, G A Truitt. Toxicity of human recombinant interleukin-2 in the mouse is mediated by interleukin-activated lymphocytes. Separation of efficacy and toxicity by selective lymphocyte subset depletion.
Laboratory investigation; a journal of technical methods and pathology.
1988 Nov; 59(5):598-612. doi:
NULL. [PMID: 3263543]