beta-Aminoarteether maleate (BioDeep_00001032555)
代谢物信息卡片
化学式: C19H31NO9 (417.19987160000005)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OCCN)C.C(=O)(C(=O)O)O
InChI: /m1./s1
描述信息
D009676 - Noxae > D016877 - Oxidants > D010545 - Peroxides
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Xiao Tong, Li Chen, Shi-Jun He, Jian-Ping Zuo. Artemisinin derivative SM934 in the treatment of autoimmune and inflammatory diseases: therapeutic effects and molecular mechanisms.
Acta pharmacologica Sinica.
2022 Dec; 43(12):3055-3061. doi:
10.1038/s41401-022-00978-4. [PMID: 36050518] - Zemin Lin, Yuting Liu, Li Chen, Shiqi Cao, Yueteng Huang, Xiaoqian Yang, Fenghua Zhu, Wei Tang, Shijun He, Jianping Zuo. Artemisinin analogue SM934 protects against lupus-associated antiphospholipid syndrome via activation of Nrf2 and its targets.
Science China. Life sciences.
2021 Oct; 64(10):1702-1719. doi:
10.1007/s11427-020-1840-1. [PMID: 33481164] - Fang-Ming Yang, Di Fan, Xiao-Qian Yang, Feng-Hua Zhu, Mei-Juan Shao, Qian Li, Yu-Ting Liu, Ze-Min Lin, Shi-Qi Cao, Wei Tang, Shi-Jun He, Jian-Ping Zuo. The artemisinin analog SM934 alleviates dry eye disease in rodent models by regulating TLR4/NF-κB/NLRP3 signaling.
Acta pharmacologica Sinica.
2021 Apr; 42(4):593-603. doi:
10.1038/s41401-020-0484-5. [PMID: 32747720] - Yu-Xi Yan, Mei-Juan Shao, Qing Qi, Yan-Sheng Xu, Xiao-Qian Yang, Feng-Hua Zhu, Shi-Jun He, Pei-Lan He, Chun-Lan Feng, Yan-Wei Wu, Heng Li, Wei Tang, Jian-Ping Zuo. Artemisinin analogue SM934 ameliorates DSS-induced mouse ulcerative colitis via suppressing neutrophils and macrophages.
Acta pharmacologica Sinica.
2018 Oct; 39(10):1633-1644. doi:
10.1038/aps.2017.185. [PMID: 29849131] - Ze-Min Lin, Xiao-Qian Yang, Feng-Hua Zhu, Shi-Jun He, Wei Tang, Jian-Ping Zuo. Artemisinin analogue SM934 attenuate collagen-induced arthritis by suppressing T follicular helper cells and T helper 17 cells.
Scientific reports.
2016 11; 6(?):38115. doi:
10.1038/srep38115. [PMID: 27897259] - Yanwei Wu, Shijun He, Bingxin Bai, Luyao Zhang, Lu Xue, Zemin Lin, Xiaoqian Yang, Fenghua Zhu, Peilan He, Wei Tang, Jianping Zuo. Therapeutic effects of the artemisinin analog SM934 on lupus-prone MRL/lpr mice via inhibition of TLR-triggered B-cell activation and plasma cell formation.
Cellular & molecular immunology.
2016 05; 13(3):379-90. doi:
10.1038/cmi.2015.13. [PMID: 25942599] - Tian-tian Li, Xiao-hui Zhang, Jing-feng Jing, Xin Li, Xiao-qian Yang, Feng-hua Zhu, Wei Tang, Jian-ping Zuo. Artemisinin analogue SM934 ameliorates the proteinuria and renal fibrosis in rat experimental membranous nephropathy.
Acta pharmacologica Sinica.
2015 Feb; 36(2):188-99. doi:
10.1038/aps.2014.134. [PMID: 25619396] - Li-Fei Hou, Shi-Jun He, Xin Li, Chun-Ping Wan, Yang Yang, Xiao-Hui Zhang, Pei-Lan He, Yu Zhou, Feng-Hua Zhu, Yi-Fu Yang, Ying Li, Wei Tang, Jian-Ping Zuo. SM934 treated lupus-prone NZB × NZW F1 mice by enhancing macrophage interleukin-10 production and suppressing pathogenic T cell development.
PloS one.
2012; 7(2):e32424. doi:
10.1371/journal.pone.0032424. [PMID: 22389703] - Li-Fei Hou, Shi-Jun He, Xin Li, Yang Yang, Pei-Lan He, Yu Zhou, Feng-Hua Zhu, Yi-Fu Yang, Ying Li, Wei Tang, Jian-Ping Zuo. Oral administration of artemisinin analog SM934 ameliorates lupus syndromes in MRL/lpr mice by inhibiting Th1 and Th17 cell responses.
Arthritis and rheumatism.
2011 Aug; 63(8):2445-55. doi:
10.1002/art.30392. [PMID: 21484768]