(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octane (BioDeep_00001031826)
代谢物信息卡片
(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octane
化学式: C8H15N (125.120443)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CN1C2CCCC1CC2
InChI: InChI=1S/C8H15N/c1-9-7-3-2-4-8(9)6-5-7/h7-8H,2-6H2,1H3/t7-,8+
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
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Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Guoyin Kai, Ang Zhang, Yingying Guo, Li Li, Lijie Cui, Xiuqin Luo, Cong Liu, Jianbo Xiao. Enhancing the production of tropane alkaloids in transgenic Anisodus acutangulus hairy root cultures by over-expressing tropinone reductase I and hyoscyamine-6β-hydroxylase.
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Zeitschrift fur Naturforschung. C, Journal of biosciences.
2008 May; 63(5-6):321-5. doi:
10.1515/znc-2008-5-602. [PMID: 18669014] - M Laura Parnas, Jon D Gaffaney, Mu Fa Zou, John R Lever, Amy Hauck Newman, Roxanne A Vaughan. Labeling of dopamine transporter transmembrane domain 1 with the tropane ligand N-[4-(4-azido-3-[125I]iodophenyl)butyl]-2beta-carbomethoxy-3beta-(4-chlorophenyl)tropane implicates proximity of cocaine and substrate active sites.
Molecular pharmacology.
2008 Apr; 73(4):1141-50. doi:
10.1124/mol.107.043679. [PMID: 18216182] - Yoshihiko Nakamura, Kenji Aratake, Ayumi Fujita, Takashi Kanemura, Takesi Nishida, Hitoshi Tanaka, Shigeki Tomojiri. [Retrospective study of two cases of acute datura poisoning].
Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology.
2008 Apr; 21(2):177-81. doi:
NULL. [PMID: 18516943] - Soad A El-Zayat, Mortada S M Nassar, Farida T El-Hissy, Fatma F Abdel-Motaal, Shin-ichi Ito. Mycoflora associated with Hyoscyamus muticus growing under an extremely arid desert environment (Aswan region, Egypt).
Journal of basic microbiology.
2008 Apr; 48(2):82-92. doi:
10.1002/jobm.200700107. [PMID: 18383230] - Barbara Andreola, Anna Piovan, Liviana Da Dalt, Raffaella Filippini, Elsa Cappelletti. Unilateral mydriasis due to Angel's trumpet.
Clinical toxicology (Philadelphia, Pa.).
2008 Apr; 46(4):329-31. doi:
10.1080/15563650701378720. [PMID: 18363132] - Peter C Meltzer, Olga Kryatova, Duy-Phong Pham-Huu, Patrick Donovan, Aaron Janowsky. The synthesis of bivalent 2beta-carbomethoxy-3beta-(3,4-dichlorophenyl)-8-heterobicyclo[3.2.1]octanes as probes for proximal binding sites on the dopamine and serotonin transporters.
Bioorganic & medicinal chemistry.
2008 Feb; 16(4):1832-41. doi:
10.1016/j.bmc.2007.11.009. [PMID: 18053732] - Tommaso R I Cataldi, Giuliana Bianco. Capillary electrophoresis of tropane alkaloids and glycoalkaloids occurring in Solanaceae plants.
Methods in molecular biology (Clifton, N.J.).
2008; 384(?):171-203. doi:
10.1007/978-1-59745-376-9_9. [PMID: 18392571] - Mona M Hanna, Nahed M Eid, Riham F George, Hani M Safwat. Synthesis of some tropane derivatives of anticipated activity on the reuptake of norepinephrine and/or serotonin.
Bioorganic & medicinal chemistry.
2007 Dec; 15(24):7765-72. doi:
10.1016/j.bmc.2007.08.055. [PMID: 17870537] - Joachim Stöckigt, Santosh Panjikar. Structural biology in plant natural product biosynthesis--architecture of enzymes from monoterpenoid indole and tropane alkaloid biosynthesis.
Natural product reports.
2007 Dec; 24(6):1382-400. doi:
10.1039/b711935f. [PMID: 18033585] - Sonia Gómez-Galera, Ana M Pelacho, Anna Gené, Teresa Capell, Paul Christou. The genetic manipulation of medicinal and aromatic plants.
Plant cell reports.
2007 Oct; 26(10):1689-715. doi:
10.1007/s00299-007-0384-x. [PMID: 17609957] - Kirsi-Marja Oksman-Caldentey. Tropane and nicotine alkaloid biosynthesis-novel approaches towards biotechnological production of plant-derived pharmaceuticals.
Current pharmaceutical biotechnology.
2007 Aug; 8(4):203-10. doi:
10.2174/138920107781387401. [PMID: 17691989] - John K Brooks, Mark A Reynolds. Ethnobotanical tattooing of the gingiva: literature review and report of a case.
Journal of the American Dental Association (1939).
2007 Aug; 138(8):1097-101. doi:
10.14219/jada.archive.2007.0322. [PMID: 17670877] - Vishakantha Murthy, Huw M L Davies, Simon J Hedley, Steven R Childers. Irreversible binding of a novel phenylisothiocyanate tropane analog to monoamine transporters in rat brain.
Biochemical pharmacology.
2007 Jul; 74(2):336-44. doi:
10.1016/j.bcp.2007.04.019. [PMID: 17540345] - Ji Yun Min, Hee Young Jung, Seung Mi Kang, Yong Duck Kim, Young Min Kang, Dong Jin Park, Doddananjappa Theertha Prasad, Myung Suk Choi. Production of tropane alkaloids by small-scale bubble column bioreactor cultures of Scopolia parviflora adventitious roots.
Bioresource technology.
2007 Jul; 98(9):1748-53. doi:
10.1016/j.biortech.2006.07.033. [PMID: 16965915] - A R Iranbakhsh, M A Oshagi, M Ebadi. Growth and production optimization of tropane alkaloids in Datura stramonium cell suspension culture.
Pakistan journal of biological sciences : PJBS.
2007 Apr; 10(8):1236-42. doi:
10.3923/pjbs.2007.1236.1242. [PMID: 19069922] - Michael Teuber, Mohammad E Azemi, Foroogh Namjoyan, Anna-Carolin Meier, Anja Wodak, Wolfgang Brandt, Birgit Dräger. Putrescine N-methyltransferases--a structure-function analysis.
Plant molecular biology.
2007 Apr; 63(6):787-801. doi:
10.1007/s11103-006-9126-7. [PMID: 17221359] - Lei Zhang, Bin Yang, Beibei Lu, Guoyin Kai, Zinan Wang, Yang Xia, Ruxian Ding, Hanming Zhang, Xiaofen Sun, Wansheng Chen, Kexuan Tang. Tropane alkaloids production in transgenic Hyoscyamus niger hairy root cultures over-expressing putrescine N-methyltransferase is methyl jasmonate-dependent.
Planta.
2007 Mar; 225(4):887-96. doi:
10.1007/s00425-006-0402-1. [PMID: 17004056] - William G Heim, Katie A Sykes, Sherry B Hildreth, Jian Sun, Rong-He Lu, John G Jelesko. Cloning and characterization of a Nicotiana tabacum methylputrescine oxidase transcript.
Phytochemistry.
2007 Feb; 68(4):454-63. doi:
10.1016/j.phytochem.2006.11.003. [PMID: 17174363] - Marcos Nopper Alves, Adilson Sartoratto, José Roberto Trigo. Scopolamine in Brugmansia suaveolens (Solanaceae): defense, allocation, costs, and induced response.
Journal of chemical ecology.
2007 Feb; 33(2):297-309. doi:
10.1007/s10886-006-9214-9. [PMID: 17195118] - Wadad Saba, Héric Valette, Marie-Anne Schöllhorn-Peyronneau, Christine Coulon, Michele Ottaviani, Sylvie Chalon, Frédéric Dolle, Patrick Emond, Christer Halldin, Julie Helfenbein, Jean-Claude Madelmont, Jean-Bernard Deloye, Denis Guilloteau, Michel Bottlaender. [11C]LBT-999: a suitable radioligand for investigation of extra-striatal dopamine transporter with PET.
Synapse (New York, N.Y.).
2007 Jan; 61(1):17-23. doi:
10.1002/syn.20337. [PMID: 17068778] - Ernesto Gianoli, Marco A Molina-Montenegro, José Becerra. Interactive effects of leaf damage, light intensity and support availability on chemical defenses and morphology of a twining vine.
Journal of chemical ecology.
2007 Jan; 33(1):95-103. doi:
10.1007/s10886-006-9215-8. [PMID: 17111219] - Ute Richter, Uwe Sonnewald, Birgit Dräger. Calystegines in potatoes with genetically engineered carbohydrate metabolism.
Journal of experimental botany.
2007; 58(7):1603-15. doi:
10.1093/jxb/erl295. [PMID: 17431026] - Patricia L Marconi, María A Alvarez, Sandra I Pitta-Alvarez. How polyamine synthesis inhibitors and cinnamic acid affect tropane alkaloid production.
Applied biochemistry and biotechnology.
2007 Jan; 136(1):63-75. doi:
10.1007/bf02685939. [PMID: 17416978] - Heike Kaiser, Ute Richter, Ronald Keiner, Anja Brabant, Bettina Hause, Birgit Dräger. Immunolocalisation of two tropinone reductases in potato (Solanum tuberosum L.) root, stolon, and tuber sprouts.
Planta.
2006 Dec; 225(1):127-37. doi:
10.1007/s00425-006-0335-8. [PMID: 16845528] - Suhong Zhang, Sari Izenwasser, Dean Wade, Liang Xu, Mark L Trudell. Synthesis of dopamine transporter selective 3-diarylmethoxymethyl-8-arylalkyl-8-azabicyclo[3.2.1]octane derivatives.
Bioorganic & medicinal chemistry.
2006 Dec; 14(23):7943-52. doi:
10.1016/j.bmc.2006.07.051. [PMID: 16905323] - Peter Ondra, Katerina Zedníková, Ivo Válka. Detection and determination of abused hallucinogens in biological material.
Neuro endocrinology letters.
2006 Dec; 27 Suppl 2(?):125-9. doi:
NULL. [PMID: 17159796] - M R Lee. Solanaceae III: henbane, hags and Hawley Harvey Crippen.
The journal of the Royal College of Physicians of Edinburgh.
2006 Dec; 36(4):366-73. doi:
". [PMID: 17526134] - Amy Hauck Newman, Joo Hwan Cha, Jianjing Cao, Theresa Kopajtic, Jonathan L Katz, M Laura Parnas, Roxanne Vaughan, John R Lever. Design and synthesis of a novel photoaffinity ligand for the dopamine and serotonin transporters based on 2beta-carbomethoxy-3beta-biphenyltropane.
Journal of medicinal chemistry.
2006 Nov; 49(22):6621-5. doi:
10.1021/jm0603973. [PMID: 17064081] - Kimiko Matsuda, Mutsuko Morinaga, Misao Okamoto, Shuhei Miyazaki, Tsuyoshi Isimaru, Kouichiro Suzuki, Kaoru Tohyama. [Toxicological analysis of a case of Datura stramonium poisoning].
Rinsho byori. The Japanese journal of clinical pathology.
2006 Oct; 54(10):1003-7. doi:
NULL. [PMID: 17133988] - Beum Jun Kim, Donna M Gibson, Michael L Shuler. Effect of the plant peptide regulator, phytosulfokine-alpha, on the growth and Taxol production from Taxus sp. suspension cultures.
Biotechnology and bioengineering.
2006 Sep; 95(1):8-14. doi:
10.1002/bit.20934. [PMID: 16586507]