Thiamine triphosphorate (BioDeep_00001031089)

   


代谢物信息卡片


Thiamine triphosphorate

化学式: C12H19N4O10P3S (504.0035)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=C(SC=[N+]1CC2=CN=C(N=C2N)C)CCOP(=O)(O)OP(=O)(O)OP(=O)(O)[O-]
InChI: InChI=1S/C12H19N4O10P3S/c1-8-11(30-7-16(8)6-10-5-14-9(2)15-12(10)13)3-4-24-28(20,21)26-29(22,23)25-27(17,18)19/h5,7H,3-4,6H2,1-2H3,(H5-,13,14,15,17,18,19,20,21,22,23)

描述信息

D018977 - Micronutrients > D014815 - Vitamins

同义名列表

1 个代谢物同义名

Thiamine triphosphorate



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Aymeric Goyer, Ghulam Hasnain, Océane Frelin, Maria A Ralat, Jesse F Gregory, Andrew D Hanson. A cross-kingdom Nudix enzyme that pre-empts damage in thiamin metabolism. The Biochemical journal. 2013 Sep; 454(3):533-42. doi: 10.1042/bj20130516. [PMID: 23834287]
  • Iu M Parkhomenko, A A Strokina, S Iu Pilipchuk, S P Stepanenko, L I Chekhovskaia, G V Donchenko. [Existence of two different active sites on thiamine binding protein in plasma membranes of synaptosomes]. Ukrains'kyi biokhimichnyi zhurnal (1999 ). 2010 Jan; 82(1):34-41. doi: . [PMID: 20684226]
  • Michel Frédérich, David Delvaux, Tiziana Gigliobianco, Marjorie Gangolf, Georges Dive, Gabriel Mazzucchelli, Benjamin Elias, Edwin De Pauw, Luc Angenot, Pierre Wins, Lucien Bettendorff. Thiaminylated adenine nucleotides. Chemical synthesis, structural characterization and natural occurrence. The FEBS journal. 2009 Jun; 276(12):3256-68. doi: 10.1111/j.1742-4658.2009.07040.x. [PMID: 19438713]
  • A A Sidorova, S P Stepanenko, Iu M Parkhomenko. [Characteristics of thiamine triphosphatase from neural cells plasma membranes]. Ukrains'kyi biokhimichnyi zhurnal (1999 ). 2009 May; 81(3):57-65. doi: NULL. [PMID: 19877430]
  • S Bäckermann, C Poel, W Ternes. Thiamin phosphates in egg yolk granules and plasma of regular and embryonated eggs of hens and in five- and seven-day-old embryos. Poultry science. 2008 Jan; 87(1):108-15. doi: 10.3382/ps.2007-00158. [PMID: 18079459]
  • Hiroshi Ihara, Takayuki Matsumoto, Yoshio Shino, Naotaka Hashizume. Assay values for thiamine or thiamine phosphate esters in whole blood do not depend on the anticoagulant used. Journal of clinical laboratory analysis. 2005; 19(5):205-8. doi: 10.1002/jcla.20079. [PMID: 16170809]
  • Alexander F Makarchikov, Pierre Wins, Edwin Janssen, Bé Wieringa, Thierry Grisar, Lucien Bettendorff. Adenylate kinase 1 knockout mice have normal thiamine triphosphate levels. Biochimica et biophysica acta. 2002 Oct; 1592(2):117-21. doi: 10.1016/s0167-4889(02)00277-x. [PMID: 12379473]
  • A F Makarchikov, I P Chernikevich. Thiamine triphosphatase activity in bovine kidney. Biochemistry and molecular biology international. 1998 Sep; 46(1):115-23. doi: 10.1080/15216549800203622. [PMID: 9784846]
  • Y Egi, S Koyama, T Shioda, K Yamada, T Kawasaki. Identification, purification and reconstitution of thiamin metabolizing enzymes in human red blood cells. Biochimica et biophysica acta. 1992 Nov; 1160(2):171-8. doi: 10.1016/0167-4838(92)90004-w. [PMID: 1332781]
  • C M Tallaksen, T Bøhmer, H Bell. Blood and serum thiamin and thiamin phosphate esters concentrations in patients with alcohol dependence syndrome before and after thiamin treatment. Alcoholism, clinical and experimental research. 1992 Apr; 16(2):320-5. doi: 10.1111/j.1530-0277.1992.tb01384.x. [PMID: 1317136]
  • B L Lee, H Y Ong, C N Ong. Determination of thiamine and its phosphate esters by gradient-elution high-performance liquid chromatography. Journal of chromatography. 1991 Jun; 567(1):71-80. doi: 10.1016/0378-4347(91)80311-y. [PMID: 1918262]
  • C M Tallaksen, T Bøhmer, H Bell, J Karlsen. Concomitant determination of thiamin and its phosphate esters in human blood and serum by high-performance liquid chromatography. Journal of chromatography. 1991 Mar; 564(1):127-36. doi: 10.1016/0378-4347(91)80075-n. [PMID: 1860908]
  • G Rindi, C Reggiani, C Patrini, U Laforenza. Effect of ethanol administration on the in vivo kinetics of thiamine phosphorylation and dephosphorylation in different organs. I. Chronic effects. Alcohol and alcoholism (Oxford, Oxfordshire). 1991; 26(3):285-301. doi: 10.1093/oxfordjournals.alcalc.a045114. [PMID: 1930361]
  • L Bettendorff, L Weekers, P Wins, E Schoffeniels. Injection of sulbutiamine induces an increase in thiamine triphosphate in rat tissues. Biochemical pharmacology. 1990 Dec; 40(11):2557-60. doi: 10.1016/0006-2952(90)90099-7. [PMID: 2268373]
  • T Matsuda, H Tonomura, A Baba, H Iwata. Tissue difference in cellular localization of thiamine phosphate esters. Comparative biochemistry and physiology. B, Comparative biochemistry. 1989; 94(2):405-9. doi: 10.1016/0305-0491(89)90364-7. [PMID: 2591202]
  • L Bettendorff, C Grandfils, C De Rycker, E Schoffeniels. Determination of thiamine and its phosphate esters in human blood serum at femtomole levels. Journal of chromatography. 1986 Oct; 382(?):297-302. doi: 10.1016/s0378-4347(00)83533-1. [PMID: 3782398]
  • G Tettamanti. [Latest data on chemical properties and the physiological role of thiamine and its phosphoric esters]. Minerva dietologica e gastroenterologica. 1985 Apr; 31(2):75-94. doi: NULL. [PMID: 3897910]
  • R Bitsch, J Hansen, D Hötzel. Thiamin Metabolism in the rat during long-term alcohol administration. 1. Communication: ethanol induced changes at optimal thiamin supply. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition. 1982; 52(2):126-33. doi: . [PMID: 6890048]
  • C Patrini, G Rindi. An improved method for the electrophoretic separation and fluorometric determination of thiamine and its phosphates in animal tissues. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition. 1980; 50(1):10-8. doi: NULL. [PMID: 7390709]
  • J H Pincus, J R Cooper, V L Turner, K Piros. Urine test in SNE. Neurology. 1979 Mar; 29(3):424-5. doi: 10.1212/wnl.29.3.424-b. [PMID: 571998]
  • I L Pshetakovskiĭ. [Justification for using thiamine and its coenzyme form in osteoarthrosis deformans in the process of peloid therapy]. Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury. 1979 Mar; ?(2):43-7. doi: NULL. [PMID: 433179]
  • K Ishii, K Sarai, H Sanemori, T Kawasaki. Concentrations of thiamine and its phosphate esters in rat tissues determined by high-performance liquid chromatography. Journal of nutritional science and vitaminology. 1979; 25(6):517-23. doi: 10.3177/jnsv.25.517. [PMID: 541755]
  • O V Popov, R R Smiller. [State of glucocorticoid activity in patients with different histologic variants of Hodgkin's disease]. Problemy gematologii i perelivaniia krovi. 1977 Jan; 22(1):11-5. doi: NULL. [PMID: 834733]
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