5,6-Didehydrosparteine (BioDeep_00001031031)
代谢物信息卡片
化学式: C15H24N2 (232.19393839999998)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1CCN2CC3CC(C2C1)CN4C3=CCCC4
InChI: InChI=1S/C15H24N2/c1-3-7-16-11-13-9-12(14(16)5-1)10-17-8-4-2-6-15(13)17/h5,12-13,15H,1-4,6-11H2/t12-,13-,15-/m0/s1
描述信息
A quinolizidine alkaloid obtained by formal dehydrogenation at the 5,6-position of sparteine. It is a metabolite of sparteine found in human urine and plasma.
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1 个代谢物同义名
数据库引用编号
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代谢反应
0 个相关的代谢反应过程信息。
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- F Kees, L Färber, M Bucher, G Mair, K Mörike, H Grobecker. Pharmacokinetics of therapeutic doses of tropisetron in healthy volunteers.
British journal of clinical pharmacology.
2001 Dec; 52(6):705-7. doi:
10.1046/j.0306-5251.2001.01512.x. [PMID: 11736884] - M Veningerová, V Prachar, M Lukácsová, J Glasa, J Holomán. Rapid determination of sparteine and its metabolites in urine.
Journal of chromatography.
1993 Dec; 622(2):274-7. doi:
10.1016/0378-4347(93)80277-b. [PMID: 8150877] - J Moncrieff. Simultaneous determination of sparteine and its 2-dehydro and 5-dehydro metabolites in urine by high-performance liquid chromatography with electrochemical detection.
Journal of chromatography.
1990 Jul; 529(1):194-200. doi:
10.1016/s0378-4347(00)83822-0. [PMID: 2211932] - W D Paar, H Schuhler, R Fimmers, H J Dengler. Sparteine oxidation polymorphism: phenotyping by measurement of sparteine and its dehydrometabolites in plasma.
European journal of clinical pharmacology.
1989; 36(6):555-60. doi:
10.1007/bf00637735. [PMID: 2590312] - J H Schellens, H H van der Wart, J W Hoevers, D D Breimer. Gas chromatographic determination of sparteine and 2- and 5-dehydrosparteine in plasma and urine.
Journal of chromatography.
1988 Sep; 431(1):203-9. doi:
10.1016/s0378-4347(00)83086-8. [PMID: 3235532] - Y Horai, T Ishizaki, M Eichelbaum, K Hashimoto, K Chiba, H J Dengler. Further analysis of sparteine oxidation in a Japanese population and comparison with data observed in different ethnic populations.
Xenobiotica; the fate of foreign compounds in biological systems.
1988 Sep; 18(9):1077-84. doi:
10.3109/00498258809042230. [PMID: 3227705] - T D Arias, L F Jorge, D Lee, R Barrantes, T Inaba. The oxidative metabolism of sparteine in the Cuna Amerindians of Panama: absence of evidence for deficient metabolizers.
Clinical pharmacology and therapeutics.
1988 Apr; 43(4):456-65. doi:
10.1038/clpt.1988.58. [PMID: 3356089] - M Eichelbaum, S Mineshita, E E Ohnhaus, C Zekorn. The influence of enzyme induction on polymorphic sparteine oxidation.
British journal of clinical pharmacology.
1986 Jul; 22(1):49-53. doi:
10.1111/j.1365-2125.1986.tb02879.x. [PMID: 3741726] - N M Woolhouse, M Eichelbaum, N S Oates, J R Idle, R L Smith. Dissociation of co-regulatory control of debrisoquin/phenformin and sparteine oxidation in Ghanaians.
Clinical pharmacology and therapeutics.
1985 May; 37(5):512-21. doi:
10.1038/clpt.1985.81. [PMID: 3987174]