(5Z,8Z,11Z,13E,15E,18S)-17,18-dihydroxyicosa-5,8,11,13,15-pentaenoic acid (BioDeep_00001030656)
代谢物信息卡片
化学式: C20H30O4 (334.2144)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCC(C(C=CC=CC=CCC=CCC=CCCCC(=O)O)O)O
InChI: InChI=1S/C20H30O4/c1-2-18(21)19(22)16-14-12-10-8-6-4-3-5-7-9-11-13-15-17-20(23)24/h3,5-6,8-12,14,16,18-19,21-22H,2,4,7,13,15,17H2,1H3,(H,23,24)/b5-3-,8-6-,11-9-,12-10+,16-14+/t18-,19?/m0/s1
相关代谢途径
Reactome(4)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Shota Arai, Koichi Fujiwara, Masahiro Kojima, Haruka Aoki-Saito, Masakiyo Yatomi, Tsugumichi Saito, Yasuhiko Koga, Hayato Fukuda, Mizuki Watanabe, Shigeki Matsunaga, Takeshi Hisada, Satoshi Shuto. Design and Synthesis of Cyclopropane Congeners of Resolvin E3, an Endogenous Pro-Resolving Lipid Mediator, as Its Stable Equivalents.
The Journal of organic chemistry.
2022 08; 87(15):10501-10508. doi:
10.1021/acs.joc.2c01110. [PMID: 35866588] - Anne Barden, Michael Phillips, Sujata Shinde, Tomas Corcoran, Trevor A Mori. The effects of perioperative dexamethasone on eicosanoids and mediators of inflammation resolution: A sub-study of the PADDAG trial.
Prostaglandins, leukotrienes, and essential fatty acids.
2021 10; 173(?):102334. doi:
10.1016/j.plefa.2021.102334. [PMID: 34455200] - Hayato Fukuda, Hiroyuki Ikeda, Ryuta Muromoto, Koki Hirashima, Kohei Ishimura, Koichi Fujiwara, Haruka Aoki-Saito, Takeshi Hisada, Mizuki Watanabe, Jun Ishihara, Tadashi Matsuda, Satoshi Shuto. Synthesis of Resolvin E3, a Proresolving Lipid Mediator, and Its Deoxy Derivatives: Identification of 18-Deoxy-resolvin E3 as a Potent Anti-Inflammatory Agent.
The Journal of organic chemistry.
2020 11; 85(21):14190-14200. doi:
10.1021/acs.joc.0c01701. [PMID: 32942849] - Makiko Sato, Haruka Aoki-Saito, Hayato Fukuda, Hiroyuki Ikeda, Yasuhiko Koga, Masakiyo Yatomi, Hiroaki Tsurumaki, Toshitaka Maeno, Tsugumichi Saito, Takashi Nakakura, Tetsuya Mori, Masataka Yanagawa, Mitsuhiro Abe, Yasushi Sako, Kunio Dobashi, Tamotsu Ishizuka, Masanobu Yamada, Satoshi Shuto, Takeshi Hisada. Resolvin E3 attenuates allergic airway inflammation via the interleukin-23-interleukin-17A pathway.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2019 11; 33(11):12750-12759. doi:
10.1096/fj.201900283r. [PMID: 31469599] - Nobuaki Tanaka, Yasuhiro Irino, Masakazu Shinohara, Shigeyasu Tsuda, Takeshige Mori, Manabu Nagao, Toshihiko Oshita, Kenta Mori, Tetsuya Hara, Ryuji Toh, Tatsuro Ishida, Ken-Ichi Hirata. Eicosapentaenoic Acid-Enriched High-Density Lipoproteins Exhibit Anti-Atherogenic Properties.
Circulation journal : official journal of the Japanese Circulation Society.
2018 01; 82(2):596-601. doi:
10.1253/circj.cj-17-0294. [PMID: 28652532] - Masanori Katakura, Michio Hashimoto, Takayuki Inoue, Abdullah Al Mamun, Yoko Tanabe, Makoto Arita, Osamu Shido. Chronic Arachidonic Acid Administration Decreases Docosahexaenoic Acid- and Eicosapentaenoic Acid-Derived Metabolites in Kidneys of Aged Rats.
PloS one.
2015; 10(10):e0140884. doi:
10.1371/journal.pone.0140884. [PMID: 26485038] - Aki Yamashita, Kei Kawana, Kensuke Tomio, Ayumi Taguchi, Yosuke Isobe, Ryo Iwamoto, Koji Masuda, Hitomi Furuya, Takeshi Nagamatsu, Kazunori Nagasaka, Takahide Arimoto, Katsutoshi Oda, Osamu Wada-Hiraike, Takahiro Yamashita, Yuji Taketani, Jing X Kang, Shiro Kozuma, Hiroyuki Arai, Makoto Arita, Yutaka Osuga, Tomoyuki Fujii. Increased tissue levels of omega-3 polyunsaturated fatty acids prevents pathological preterm birth.
Scientific reports.
2013 Nov; 3(?):3113. doi:
10.1038/srep03113. [PMID: 24177907] - Yosuke Isobe, Makoto Arita, Ryo Iwamoto, Daisuke Urabe, Hidenori Todoroki, Koji Masuda, Masayuki Inoue, Hiroyuki Arai. Stereochemical assignment and anti-inflammatory properties of the omega-3 lipid mediator resolvin E3.
Journal of biochemistry.
2013 Apr; 153(4):355-60. doi:
10.1093/jb/mvs151. [PMID: 23293324]
