17-beta-Estradiol-3-glucuronide (BioDeep_00001030084)

   


代谢物信息卡片


17-beta-Estradiol-3-glucuronide

化学式: C24H32O8 (448.20970719999997)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)OC5C(C(C(C(O5)C(=O)O)O)O)O
InChI: InChI=1S/C24H32O8/c1-24-9-8-14-13-5-3-12(10-11(13)2-4-15(14)16(24)6-7-17(24)25)31-23-20(28)18(26)19(27)21(32-23)22(29)30/h3,5,10,14-21,23,25-28H,2,4,6-9H2,1H3,(H,29,30)/t14-,15-,16+,17+,18+,19+,20-,21+,23?,24+/m1/s1

描述信息

同义名列表

1 个代谢物同义名

17-beta-Estradiol-3-glucuronide



数据库引用编号

2 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

12 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(12)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Ayako Kato, Jun Ueyama, Fumie Abe, Kazuo Hotta, Ikuto Tsukiyama, Taeyuki Oshima, Fumio Kondo, Hiroko Saito, Takaaki Hasegawa. Panipenem does not alter the pharmacokinetics of the active metabolite of irinotecan SN-38 and inactive metabolite SN-38 glucuronide (SN-38G) in rats. Anticancer research. 2011 Sep; 31(9):2915-22. doi: . [PMID: 21868538]
  • Mohamed-Eslam F Mohamed, Tiffany Tseng, Reginald F Frye. Inhibitory effects of commonly used herbal extracts on UGT1A1 enzyme activity. Xenobiotica; the fate of foreign compounds in biological systems. 2010 Oct; 40(10):663-9. doi: 10.3109/00498254.2010.505669. [PMID: 20666626]
  • Jeffrey C Sivils, Iven Gonzalez, Lisa J Bain. Mice lacking Mrp1 have reduced testicular steroid hormone levels and alterations in steroid biosynthetic enzymes. General and comparative endocrinology. 2010 May; 167(1):51-9. doi: 10.1016/j.ygcen.2010.02.019. [PMID: 20178799]
  • Niina M Saarinen, Annika I Smeds, José L Peñalvo, Tarja Nurmi, Herman Adlercreutz, Sari Mäkelä. Flaxseed ingestion alters ratio of enterolactone enantiomers in human serum. Journal of nutrition and metabolism. 2010; 2010(?):. doi: 10.1155/2010/403076. [PMID: 20721350]
  • Masakazu Hirouchi, Hiroyuki Kusuhara, Reiko Onuki, Brian W Ogilvie, Andrew Parkinson, Yuichi Sugiyama. Construction of triple-transfected cells [organic anion-transporting polypeptide (OATP) 1B1/multidrug resistance-associated protein (MRP) 2/MRP3 and OATP1B1/MRP2/MRP4] for analysis of the sinusoidal function of MRP3 and MRP4. Drug metabolism and disposition: the biological fate of chemicals. 2009 Oct; 37(10):2103-11. doi: 10.1124/dmd.109.027193. [PMID: 19628752]
  • Chun Chu, Jian Yi Li, Ruben J Boado, William M Pardridge. Blood-brain barrier genomics and cloning of a novel organic anion transporter. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2008 Feb; 28(2):291-301. doi: 10.1038/sj.jcbfm.9600538. [PMID: 17667996]
  • Lay Beng Goh, Kevin J Spears, Denggao Yao, Andy Ayrton, Paul Morgan, C Roland Wolf, Thomas Friedberg. Endogenous drug transporters in in vitro and in vivo models for the prediction of drug disposition in man. Biochemical pharmacology. 2002 Dec; 64(11):1569-78. doi: 10.1016/s0006-2952(02)01355-2. [PMID: 12429346]
  • Kenkichi Hashimoto, Takeshi Uchiumi, Toshikazu Konno, Takuya Ebihara, Takanori Nakamura, Morimasa Wada, Shotaro Sakisaka, Fumio Maniwa, Teruo Amachi, Kazumitsu Ueda, Michihiko Kuwano. Trafficking and functional defects by mutations of the ATP-binding domains in MRP2 in patients with Dubin-Johnson syndrome. Hepatology (Baltimore, Md.). 2002 Nov; 36(5):1236-45. doi: 10.1053/jhep.2002.36368. [PMID: 12395335]
  • S H Cha, T Sekine, J I Fukushima , Y Kanai, Y Kobayashi, T Goya, H Endou. Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney. Molecular pharmacology. 2001 May; 59(5):1277-86. doi: 10.1124/mol.59.5.1277. [PMID: 11306713]
  • T D Lund, T W West, L Y Tian, L H Bu, D L Simmons, K D Setchell, H Adlercreutz, E D Lephart. Visual spatial memory is enhanced in female rats (but inhibited in males) by dietary soy phytoestrogens. BMC neuroscience. 2001; 2(?):20. doi: 10.1186/1471-2202-2-20. [PMID: 11801187]