sialyl Lewis(x) (BioDeep_00001029940)
代谢物信息卡片
sialyl Lewis(x)
化学式: C31H52N2O23 (820.2961)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1C(C(C(C(O1)OC2C(C(OC(C2OC3C(C(C(C(O3)CO)O)OC4(CC(C(C(O4)C(C(CO)O)O)NC(=O)C)O)C(=O)O)O)CO)O)NC(=O)C)O)O)O
InChI: InChI=1S/C31H52N2O23/c1-8-17(41)20(44)21(45)28(50-8)54-25-16(33-10(3)38)27(47)51-14(7-36)23(25)53-29-22(46)26(19(43)13(6-35)52-29)56-31(30(48)49)4-11(39)15(32-9(2)37)24(55-31)18(42)12(40)5-34/h8,11-29,34-36,39-47H,4-7H2,1-3H3,(H,32,37)(H,33,38)(H,48,49)/t8-,11-,12+,13+,14+,15+,16+,17+,18+,19-,20+,21-,22+,23+,24+,25+,26-,27+,28-,29-,31-/m0/s1
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Minhui Guan, Alicia K Olivier, Xiaotong Lu, William Epperson, Xiaojian Zhang, Lei Zhong, Kaitlyn Waters, Nataly Mamaliger, Lei Li, Feng Wen, Yizhi J Tao, Thomas J DeLiberto, Xiu-Feng Wan. The Sialyl Lewis X Glycan Receptor Facilitates Infection of Subtype H7 Avian Influenza A Viruses.
Journal of virology.
2022 10; 96(19):e0134422. doi:
10.1128/jvi.01344-22. [PMID: 36125302] - Wei Xiong, Wenxin Liu, Shogo Nishida, Daichi Komiyama, Wei Liu, Jotaro Hirakawa, Hiroto Kawashima. Therapeutic Effects of an Anti-sialyl Lewis X Antibody in a Murine Model of Allergic Asthma.
International journal of molecular sciences.
2021 Sep; 22(18):. doi:
10.3390/ijms22189961. [PMID: 34576124] - Georges Tarris, Alexis de Rougemont, Marie-Anaïs Estienney, Julien Journet, Anne-Cécile Lariotte, Damien Aubignat, Jean-Michel Rebibou, Mathilde Funes De La Vega, Mathieu Legendre, Gael Belliot, Laurent Martin. Chronic kidney disease linked to SARS-CoV-2 infection: a case report.
BMC nephrology.
2021 08; 22(1):278. doi:
10.1186/s12882-021-02490-z. [PMID: 34376184] - Carmen de Jesús-Gil, Lídia Sans-de San Nicolàs, Ester Ruiz-Romeu, Marta Ferran, Laura Soria-Martínez, Irene García-Jiménez, Anca Chiriac, Josep Manel Casanova-Seuma, Josep Manel Fernández-Armenteros, Sherry Owens, Antonio Celada, Michael D Howell, Ramòn María Pujol, Luis Francisco Santamaria-Babí. Interplay between Humoral and CLA+ T Cell Response against Candida albicans in Psoriasis.
International journal of molecular sciences.
2021 Feb; 22(4):. doi:
10.3390/ijms22041519. [PMID: 33546306] - Mayanka Awasthi, Sahil Gulati, Debi P Sarkar, Swasti Tiwari, Suneel Kateriya, Peeyush Ranjan, Santosh Kumar Verma. The Sialoside-Binding Pocket of SARS-CoV-2 Spike Glycoprotein Structurally Resembles MERS-CoV.
Viruses.
2020 08; 12(9):. doi:
10.3390/v12090909. [PMID: 32825063] - Carmen De Jesús-Gil, Lidia Sans-de San Nicolás, Ester Ruiz-Romeu, Marta Ferran, Laura Soria-Martinez, Anca Chiriac, Antonio Celada, Ramon M Pujol, Luis F Santamaria-Babí. Specific IgA and CLA+ T-Cell IL-17 Response to Streptococcus pyogenes in Psoriasis.
The Journal of investigative dermatology.
2020 07; 140(7):1364-1370.e1. doi:
10.1016/j.jid.2019.12.022. [PMID: 31972247] - Julie Sophie Elsner, Michael Carlsson, Julie Kristine Stougaard, Uffe Nygaard, Matthias Buchner, Regina Fölster-Holst, Malene Hvid, Christian Vestergaard, Mette Deleuran, Bent Deleuran. The OX40 Axis is Associated with Both Systemic and Local Involvement in Atopic Dermatitis.
Acta dermato-venereologica.
2020 Mar; 100(6):adv00099. doi:
10.2340/00015555-3452. [PMID: 32176307] - Evan N Cohen, Tamer M Fouad, Bang-Ning Lee, Banu K Arun, Diane Liu, Sanda Tin, Angelica M Gutierrez Barrera, Toshihide Miura, Iwao Kiyokawa, Jun Yamashita, Ricardo H Alvarez, Vicente Valero, Wendy A Woodward, Yu Shen, Naoto T Ueno, Massimo Cristofanilli, James M Reuben. Elevated serum levels of sialyl Lewis X (sLeX) and inflammatory mediators in patients with breast cancer.
Breast cancer research and treatment.
2019 Aug; 176(3):545-556. doi:
10.1007/s10549-019-05258-0. [PMID: 31054033] - Senlian Hong, Yujie Shi, Nicholas C Wu, Geramie Grande, Lacey Douthit, Hua Wang, Wen Zhou, K Barry Sharpless, Ian A Wilson, Jia Xie, Peng Wu. Bacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification.
Nature communications.
2019 04; 10(1):1799. doi:
10.1038/s41467-019-09608-w. [PMID: 30996301] - Birgit Zimmermann-Geller, Sina Köppert, Nina Kesel, Rebecca Hasseli, Sebastian Ullrich, Stephanie Lefèvre, Klaus Frommer, Thorsten Gehrke, Markus Schönburg, Stephan Rehart, Udo Schumacher, Ulf Müller-Ladner, Elena Neumann. Interactions between rheumatoid arthritis synovial fibroblast migration and endothelial cells.
Immunology and cell biology.
2019 02; 97(2):178-189. doi:
10.1111/imcb.12208. [PMID: 30252968] - Yunhai Wei, Jie Shao, Yan Wang, Hua Shen, Sheng Yu, Jinyu Zhang, Lei Yin. Hsa-miR-370 inhibited P-selectin-induced cell adhesion in human colon adenocarcinoma cells.
Molecular and cellular biochemistry.
2019 Jan; 450(1-2):159-166. doi:
10.1007/s11010-018-3382-0. [PMID: 29922946] - Ruchira Engel, Laura Delvasto-Nuñez, Dorina Roem, Gerard van Mierlo, Stephanie Holst, Agnes L Hipgrave Ederveen, Jaap D van Buul, Manfred Wuhrer, Diana Wouters, Sacha Zeerleder. α1-Antichymotrypsin Present in Therapeutic C1-Inhibitor Products Competes with Selectin-Sialyl LewisX Interaction.
Thrombosis and haemostasis.
2018 Dec; 118(12):2134-2144. doi:
10.1055/s-0038-1675601. [PMID: 30453343] - M-N Theodoraki, T K Hoffmann, T L Whiteside. Separation of plasma-derived exosomes into CD3(+) and CD3(-) fractions allows for association of immune cell and tumour cell markers with disease activity in HNSCC patients.
Clinical and experimental immunology.
2018 06; 192(3):271-283. doi:
10.1111/cei.13113. [PMID: 29431869] - Nandini Mondal, Brad Dykstra, Jungmin Lee, David J Ashline, Vernon N Reinhold, Derrick J Rossi, Robert Sackstein. Distinct human α(1,3)-fucosyltransferases drive Lewis-X/sialyl Lewis-X assembly in human cells.
The Journal of biological chemistry.
2018 05; 293(19):7300-7314. doi:
10.1074/jbc.ra117.000775. [PMID: 29593094] - Vasilios A Morikis, Shannon Chase, Ted Wun, Elliot L Chaikof, John L Magnani, Scott I Simon. Selectin catch-bonds mechanotransduce integrin activation and neutrophil arrest on inflamed endothelium under shear flow.
Blood.
2017 11; 130(19):2101-2110. doi:
10.1182/blood-2017-05-783027. [PMID: 28811304] - Shuichi Kishimoto, Nobuhito Fujitani, Takanori Ohnishi, Hiroki Aoki, Ryosuke Suzuki, Shoji Fukushima. Cisplatin-loaded, Sialyl Lewis X-Modified Liposomes: Drug Release, Biodistribution and Antitumor Efficacy.
Anticancer research.
2017 11; 37(11):6055-6061. doi:
10.21873/anticanres.12053. [PMID: 29061785] - Haruhiko Nakamura, Toshihide Nishimura. History, molecular features, and clinical importance of conventional serum biomarkers in lung cancer.
Surgery today.
2017 Sep; 47(9):1037-1059. doi:
10.1007/s00595-017-1477-y. [PMID: 28229299] - Sara Ricardo, Lara Marcos-Silva, Cristina Valente, Ricardo Coelho, Rosa Gomes, Leonor David. Mucins MUC16 and MUC1 are major carriers of SLe(a) and SLe(x) in borderline and malignant serous ovarian tumors.
Virchows Archiv : an international journal of pathology.
2016 Jun; 468(6):715-22. doi:
10.1007/s00428-016-1929-6. [PMID: 27003157] - Małgorzata Borzym-Kluczyk, Iwona Radziejewska, Marzanna Cechowska-Pasko. Increased expression of MUC1 and sialyl Lewis antigens in different areas of clear renal cell carcinoma.
Clinical and experimental nephrology.
2015 Aug; 19(4):732-7. doi:
10.1007/s10157-014-1013-y. [PMID: 25091456] - Huiyuan Tang, Sudhir Singh, Katie Partyka, Doron Kletter, Peter Hsueh, Jessica Yadav, Elliot Ensink, Marshall Bern, Galen Hostetter, Douglas Hartman, Ying Huang, Randall E Brand, Brian B Haab. Glycan motif profiling reveals plasma sialyl-lewis x elevations in pancreatic cancers that are negative for sialyl-lewis A.
Molecular & cellular proteomics : MCP.
2015 May; 14(5):1323-33. doi:
10.1074/mcp.m114.047837. [PMID: 25733690] - Anna Alekseeva, Marina Kapkaeva, Olga Shcheglovitova, Ivan Boldyrev, Galina Pazynina, Nicolai Bovin, Elena Vodovozova. Interactions of antitumour Sialyl Lewis X liposomes with vascular endothelial cells.
Biochimica et biophysica acta.
2015 May; 1848(5):1099-110. doi:
10.1016/j.bbamem.2015.01.016. [PMID: 25646577] - Meritxell Balmaña, Ariadna Sarrats, Esther Llop, Sílvia Barrabés, Radka Saldova, María José Ferri, Joan Figueras, Esther Fort, Rafael de Llorens, Pauline M Rudd, Rosa Peracaula. Identification of potential pancreatic cancer serum markers: Increased sialyl-Lewis X on ceruloplasmin.
Clinica chimica acta; international journal of clinical chemistry.
2015 Mar; 442(?):56-62. doi:
10.1016/j.cca.2015.01.007. [PMID: 25595436] - Gary F Clark. A role for carbohydrate recognition in mammalian sperm-egg binding.
Biochemical and biophysical research communications.
2014 Aug; 450(3):1195-203. doi:
10.1016/j.bbrc.2014.06.051. [PMID: 24952156] - Hiroaki Komatsu, Shinjiro Mizuguchi, Nobuhiro Izumi, Kyukwang Chung, Shoji Hanada, Hidetoshi Inoue, Shigefumi Suehiro, Noritoshi Nishiyama. Sialyl Lewis X as a predictor of skip N2 metastasis in clinical stage IA non-small cell lung cancer.
World journal of surgical oncology.
2013 Dec; 11(?):309. doi:
10.1186/1477-7819-11-309. [PMID: 24313932] - Mirosława Ferens-Sieczkowska, Ewa Maria Kratz, Barbara Kossowska, Ewa Passowicz-Muszyńska, Renata Jankowska. Comparison of haptoglobin and alpha₁-acid glycoprotein glycosylation in the sera of small cell and non-small cell lung cancer patients.
Postepy higieny i medycyny doswiadczalnej (Online).
2013 Aug; 67(?):828-36. doi:
10.5604/17322693.1061788. [PMID: 24018448] - Yue Geng, Siddarth Chandrasekaran, Jong-Wei Hsu, Mishka Gidwani, Andrew D Hughes, Michael R King. Phenotypic switch in blood: effects of pro-inflammatory cytokines on breast cancer cell aggregation and adhesion.
PloS one.
2013; 8(1):e54959. doi:
10.1371/journal.pone.0054959. [PMID: 23372803] - Yoshiyuki Mizushina, Takahiko Hada, Hiromi Yoshida. In vivo antitumor effect of liposomes with sialyl Lewis X including monogalactosyl diacylglycerol, a replicative DNA polymerase inhibitor, from spinach.
Oncology reports.
2012 Sep; 28(3):821-8. doi:
10.3892/or.2012.1893. [PMID: 22767329] - Takashi Iwata, Noritoshi Nishiyama, Koshi Nagano, Nobuhiro Izumi, Takuma Tsukioka, Kyukwang Chung, Shoji Hanada, Kiyotoshi Inoue, Masahide Kaji, Shigefumi Suehiro. Preoperative serum value of sialyl Lewis X predicts pathological nodal extension and survival in patients with surgically treated small cell lung cancer.
Journal of surgical oncology.
2012 Jun; 105(8):818-24. doi:
10.1002/jso.23002. [PMID: 22170474] - Gemma Chiva-Blanch, Mireia Urpi-Sarda, Rafael Llorach, Maria Rotches-Ribalta, Marisa Guillén, Rosa Casas, Sara Arranz, Palmira Valderas-Martinez, Olga Portoles, Dolores Corella, Francisco Tinahones, Rosa M Lamuela-Raventos, Cristina Andres-Lacueva, Ramon Estruch. Differential effects of polyphenols and alcohol of red wine on the expression of adhesion molecules and inflammatory cytokines related to atherosclerosis: a randomized clinical trial.
The American journal of clinical nutrition.
2012 Feb; 95(2):326-34. doi:
10.3945/ajcn.111.022889. [PMID: 22205309] - Koji Higai, Kojiro Matsumoto. [Glycan ligand specificity of killer lectin receptors].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.
2012; 132(6):705-12. doi:
10.1248/yakushi.132.705. [PMID: 22687729] - Chaofeng Dai, Lisa H Cazares, Lifang Wang, Yong Chu, Siming L Wang, Dean A Troyer, O John Semmes, Richard R Drake, Binghe Wang. Using boronolectin in MALDI-MS imaging for the histological analysis of cancer tissue expressing the sialyl Lewis X antigen.
Chemical communications (Cambridge, England).
2011 Oct; 47(37):10338-40. doi:
10.1039/c1cc11814e. [PMID: 21853197] - R Saldova, J M Reuben, U M Abd Hamid, P M Rudd, M Cristofanilli. Levels of specific serum N-glycans identify breast cancer patients with higher circulating tumor cell counts.
Annals of oncology : official journal of the European Society for Medical Oncology.
2011 May; 22(5):1113-1119. doi:
10.1093/annonc/mdq570. [PMID: 21127012] - Go Sugiarto, Kam Lau, Hai Yu, Stephanie Vuong, Vireak Thon, Yanhong Li, Shengshu Huang, Xi Chen. Cloning and characterization of a viral α2-3-sialyltransferase (vST3Gal-I) for the synthesis of sialyl Lewisx.
Glycobiology.
2011 Mar; 21(3):387-96. doi:
10.1093/glycob/cwq172. [PMID: 20978012] - Tomoyuki Fujita, Koichi Murayama, Toru Hanamura, Toshihiro Okada, Tokiko Ito, Michihiko Harada, Akira Komatsu, Hiroshi Koyama, Toshiharu Kanai, Kazuma Maeno, Yasuhiro Mochizuki, Yoshihisa Hama, Ken-Ichi Ito, Jun Amano, Minoru Fujimori. CSLEX (Sialyl Lewis X) is a useful tumor marker for monitoring of breast cancer patients.
Japanese journal of clinical oncology.
2011 Mar; 41(3):394-9. doi:
10.1093/jjco/hyq190. [PMID: 20956388] - Irmi Wiest, Christoph Alexiou, Doris Mayr, Sandra Schulze, Christina Kuhn, Susanne Kunze, Mareike Büttner, Peter Betz, Udo Jeschke. Expression of the carbohydrate tumor marker Sialyl Lewis a (Ca19-9) in squamous cell carcinoma of the larynx.
Anticancer research.
2010 May; 30(5):1849-53. doi:
NULL. [PMID: 20592391] - Minoru Kobayashi, Tatsuo Morita. Significant expression patterns of lewis X-related antigens as a prognostic predictor of low-stage renal cell carcinomas.
Anticancer research.
2010 Feb; 30(2):593-9. doi:
NULL. [PMID: 20332476] - Sherry A Hudson, Nicolai V Bovin, Ronald L Schnaar, Paul R Crocker, Bruce S Bochner. Eosinophil-selective binding and proapoptotic effect in vitro of a synthetic Siglec-8 ligand, polymeric 6'-sulfated sialyl Lewis x.
The Journal of pharmacology and experimental therapeutics.
2009 Aug; 330(2):608-12. doi:
10.1124/jpet.109.152439. [PMID: 19458105] - Christian Gege, Gabriele Schumacher, Ulrich Rothe, Richard R Schmidt, Gerd Bendas. Visualization of sialyl Lewis(X) glycosphingolipid microdomains in model membranes as selectin recognition motifs using a fluorescence label.
Carbohydrate research.
2008 Sep; 343(14):2361-8. doi:
10.1016/j.carres.2008.07.004. [PMID: 18656853] - Anne Kaukinen, Arvi-Matti Kuusniemi, Irmeli Lautenschlager, Hannu Jalanko. Glomerular endothelium in kidneys with congenital nephrotic syndrome of the Finnish type (NPHS1).
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2008 Apr; 23(4):1224-32. doi:
10.1093/ndt/gfm799. [PMID: 18048423] - Radka Saldova, Mark R Wormald, Raymond A Dwek, Pauline M Rudd. Glycosylation changes on serum glycoproteins in ovarian cancer may contribute to disease pathogenesis.
Disease markers.
2008; 25(4-5):219-32. doi:
10.1155/2008/601583. [PMID: 19126966] - Shinjiro Mizuguchi, Noritoshi Nishiyama, Takashi Iwata, Tatsuya Nishida, Nobuhiro Izumi, Takuma Tsukioka, Kiyotoshi Inoue, Takahiro Uenishi, Kenichi Wakasa, Shigefumi Suehiro. Serum Sialyl Lewis x and cytokeratin 19 fragment as predictive factors for recurrence in patients with stage I non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands).
2007 Dec; 58(3):369-75. doi:
10.1016/j.lungcan.2007.07.002. [PMID: 17697728] - Olga Gornik, Louise Royle, David J Harvey, Catherine M Radcliffe, Radka Saldova, Raymond A Dwek, Pauline Rudd, Gordan Lauc. Changes of serum glycans during sepsis and acute pancreatitis.
Glycobiology.
2007 Dec; 17(12):1321-32. doi:
10.1093/glycob/cwm106. [PMID: 17940056] - Yukio Arakawa, Noriyasu Hashida, Nobuyuki Ohguro, Noboru Yamazaki, Mitsuko Onda, Syoji Matsumoto, Masako Ohishi, Kaoru Yamabe, Yasuo Tano, Nobuo Kurokawa. Eye-concentrated distribution of dexamethasone carried by sugar-chain modified liposome in experimental autoimmune uveoretinitis mice.
Biomedical research (Tokyo, Japan).
2007 Dec; 28(6):331-4. doi:
10.2220/biomedres.28.331. [PMID: 18202524] - Barbara G Lorz, Ana-S Smith, Christian Gege, Erich Sackmann. Adhesion of giant vesicles mediated by weak binding of sialyl-LewisX to E-selectin in the presence of repelling poly(ethylene glycol) molecules.
Langmuir : the ACS journal of surfaces and colloids.
2007 Nov; 23(24):12293-300. doi:
10.1021/la701824q. [PMID: 17918980] - Anna Olewicz-Gawlik, Izabela Korczowska-Łacka, Jan K Łacki, Kamilla Klama, Paweł Hrycaj. Fucosylation of serum alpha1-acid glycoprotein in rheumatoid arthritis patients treated with infliximab.
Clinical rheumatology.
2007 Oct; 26(10):1679-84. doi:
10.1007/s10067-007-0572-7. [PMID: 17310270] - Flordeliza S Villanueva, Erxiong Lu, Shivani Bowry, Sevgi Kilic, Eric Tom, Jianjun Wang, Joan Gretton, John J Pacella, William R Wagner. Myocardial ischemic memory imaging with molecular echocardiography.
Circulation.
2007 Jan; 115(3):345-52. doi:
10.1161/circulationaha.106.633917. [PMID: 17210843] - Shinjiro Mizuguchi, Noritoshi Nishiyama, Takashi Iwata, Tatsuya Nishida, Nobuhiro Izumi, Takuma Tsukioka, Kiyotoshi Inoue, Masao Kameyama, Shigefumi Suehiro. Clinical value of serum cytokeratin 19 fragment and sialyl-Lewis x in non-small cell lung cancer.
The Annals of thoracic surgery.
2007 Jan; 83(1):216-21. doi:
10.1016/j.athoracsur.2006.08.042. [PMID: 17184666] - Masashi Kanehara, Mihoko Doi, Kenji Nakamura, Kikuo Nakano, Takehiko Hiramoto. [A case of bronchogenic cyst with elevated SLX levels in serum and cystic fluid].
Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society.
2006 Nov; 44(11):874-8. doi:
NULL. [PMID: 17144590] - A L Klibanov, J J Rychak, W C Yang, S Alikhani, B Li, S Acton, J R Lindner, K Ley, S Kaul. Targeted ultrasound contrast agent for molecular imaging of inflammation in high-shear flow.
Contrast media & molecular imaging.
2006 Nov; 1(6):259-66. doi:
10.1002/cmmi.113. [PMID: 17191766] - Sima Allahverdian, Kimberly R Wojcik, Delbert R Dorscheid. Airway epithelial wound repair: role of carbohydrate sialyl Lewisx.
American journal of physiology. Lung cellular and molecular physiology.
2006 Oct; 291(4):L828-36. doi:
10.1152/ajplung.00120.2006. [PMID: 16751224] - Shinjiro Mizuguchi, Kiyotoshi Inoue, Takashi Iwata, Tatsuya Nishida, Nobuhiro Izumi, Takuma Tsukioka, Noritoshi Nishiyama, Takahiro Uenishi, Shigefumi Suehiro. High serum concentrations of Sialyl Lewisx predict multilevel N2 disease in non-small-cell lung cancer.
Annals of surgical oncology.
2006 Jul; 13(7):1010-8. doi:
10.1245/aso.2006.05.018. [PMID: 16788764] - Junichi Kurebayashi, Tsunehisa Nomura, Mai Hirono, Sumiko Okubo, Kiyoshi Udagawa, Shigeo Shiiki, Masahiko Ikeda, Kazutaka Nakashima, Katsuhiro Tanaka, Hiroshi Sonoo. Combined measurement of serum sialyl Lewis X with serum CA15-3 in breast cancer patients.
Japanese journal of clinical oncology.
2006 Mar; 36(3):150-3. doi:
10.1093/jjco/hyi235. [PMID: 16520359] - Akihiko Nakaizumi, Sachiko Tanaka. [Tumor markers for detecting pancreatic cancer].
Nihon rinsho. Japanese journal of clinical medicine.
2006 Jan; 64 Suppl 1(?):144-7. doi:
NULL. [PMID: 16457238] - Hironobu Eguchi, Yoshitaka Ikeda, Tomomi Ookawara, Souichi Koyota, Noriko Fujiwara, Koichi Honke, Peng G Wang, Naoyuki Taniguchi, Keiichiro Suzuki. Modification of oligosaccharides by reactive oxygen species decreases sialyl lewis x-mediated cell adhesion.
Glycobiology.
2005 Nov; 15(11):1094-101. doi:
10.1093/glycob/cwj003. [PMID: 16000697] - Jaana Niittymäki, Pirkko Mattila, Risto Renkonen. Cloning and expression of rat fucosyltransferase VII at sites of inflammation.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.
2005 Sep; 113(9):613-20. doi:
10.1111/j.1600-0463.2005.apm_279.x. [PMID: 16218937] - Hiroshi Kajiwara, Masanori Yasuda, Nobue Kumaki, Taro Shibayama, Yoshiyuki Osamura. Expression of carbohydrate antigens (SSEA-1, sialyl-Lewis X, DU-PAN-2 and CA19-9) and E-selectin in urothelial carcinoma of the renal pelvis, ureter, and urinary bladder.
The Tokai journal of experimental and clinical medicine.
2005 Sep; 30(3):177-82. doi:
NULL. [PMID: 16285609] - Claudia Keil, Reiner Zeisig, Iduna Fichtner. Effect of surface modified liposomes on the aggregation of platelets and tumor cells.
Thrombosis and haemostasis.
2005 Aug; 94(2):404-11. doi:
10.1160/th04-12-0810. [PMID: 16113832] - Tracy L Whitehead, Behjatolah Monzavi-Karbassi, Fariba Jousheghany, Cecile Artaud, Alan Elbein, Thomas Kieber-Emmons. 1H-NMR metabolic markers of malignancy correlate with spontaneous metastases in a murine mammary tumor model.
International journal of oncology.
2005 Jul; 27(1):257-63. doi:
10.3892/ijo.27.1.257. [PMID: 15942667] - Neelu Kaila, William S Somers, Bert E Thomas, Paresh Thakker, Kristin Janz, Silvano DeBernardo, Steve Tam, William J Moore, Ruiyang Yang, Wojciech Wrona, Patricia W Bedard, Deidre Crommie, James C Keith, Desiree H H Tsao, Juan C Alvarez, Heyu Ni, Erik Marchese, John T Patton, John L Magnani, Raymond T Camphausen. Quinic acid derivatives as sialyl Lewis(x)-mimicking selectin inhibitors: design, synthesis, and crystal structure in complex with E-selectin.
Journal of medicinal chemistry.
2005 Jun; 48(13):4346-57. doi:
10.1021/jm050049l. [PMID: 15974587] - Kojiro Ohba, Yasuyoshi Miyata, Shigehiko Koga, Shigeru Kanda, Hiroshi Kanetake. Expression of nm23-H1 gene product in sarcomatous cancer cells of renal cell carcinoma: correlation with tumor stage and expression of matrix metalloproteinase-2, matrix metalloproteinase-9, sialyl Lewis X, and c-erbB-2.
Urology.
2005 May; 65(5):1029-34. doi:
10.1016/j.urology.2004.12.032. [PMID: 15882758] - Keiichi Tozawa, Takashi Okamoto, Noriyasu Kawai, Yoshihiro Hashimoto, Yutaro Hayashi, Kenjiro Kohri. Positive correlation between sialyl Lewis X expression and pathologic findings in renal cell carcinoma.
Kidney international.
2005 Apr; 67(4):1391-6. doi:
10.1111/j.1523-1755.2005.00216.x. [PMID: 15780091] - Apa Juntavee, Banchob Sripa, Ake Pugkhem, Narong Khuntikeo, Sopit Wongkham. Expression of sialyl Lewis(a) relates to poor prognosis in cholangiocarcinoma.
World journal of gastroenterology.
2005 Jan; 11(2):249-54. doi:
10.3748/wjg.v11.i2.249. [PMID: 15633225] - Toshiji Ishiwata, Kazuhisa Takahashi, Yuri Shimanuki, Rina Ohashi, Ri Cui, Fumiyuki Takahashi, Kazue Shimizu, Kayo Miura, Yoshinosuke Fukuchi. Serum tenascin-C as a potential predictive marker of angiogenesis in non-small cell lung cancer.
Anticancer research.
2005 Jan; 25(1B):489-95. doi:
NULL. [PMID: 15816617] - M V Croce, V C Sálice, E Lacunza, A Segal-Eiras. Alpha 1-acid glycoprotein (AGP): a possible carrier of sialyl lewis X (slewis X) antigen in colorectal carcinoma.
Histology and histopathology.
2005 01; 20(1):91-7. doi:
10.14670/hh-20.91. [PMID: 15578427] - Laura Huopaniemi, Meelis Kolmer, Jaana Niittymäki, Markku Pelto-Huikko, Risto Renkonen. Inflammation-induced transcriptional regulation of Golgi transporters required for the synthesis of sulfo sLex glycan epitopes.
Glycobiology.
2004 Dec; 14(12):1285-94. doi:
10.1093/glycob/cwh131. [PMID: 15269183] - Lars Bode, Clemens Kunz, Marion Muhly-Reinholz, Konstantin Mayer, Werner Seeger, Silvia Rudloff. Inhibition of monocyte, lymphocyte, and neutrophil adhesion to endothelial cells by human milk oligosaccharides.
Thrombosis and haemostasis.
2004 Dec; 92(6):1402-10. doi:
10.1160/th04-01-0055. [PMID: 15583750] - Shinji Akamine, Tohru Nakagoe, Terumitsu Sawai, Takashi Tsuji, Kenji Tanaka, Shigekazu Hidaka, Shin-Ichi Shibasaki, Atsushi Nanashima, Hiroyuki Yamaguchi, Takeshi Nagayasu, Toru Yasutake. Differences in prognosis of colorectal cancer patients based on the expression of sialyl Lewisa, sialyl Lewisx and sialyl Tn antigens in serum and tumor tissue.
Anticancer research.
2004 Jul; 24(4):2541-6. doi:
NULL. [PMID: 15330211] - Reiji Kannagi, Mineko Izawa, Tetsufumi Koike, Keiko Miyazaki, Naoko Kimura. Carbohydrate-mediated cell adhesion in cancer metastasis and angiogenesis.
Cancer science.
2004 May; 95(5):377-84. doi:
10.1111/j.1349-7006.2004.tb03219.x. [PMID: 15132763] - Christian Gege, Matthias F Schneider, Gabriele Schumacher, Laurent Limozin, Ulrich Rothe, Gerd Bendas, Motomu Tanaka, Richard R Schmidt. Functional microdomains of glycolipids with partially fluorinated membrane anchors: impact on cell adhesion.
Chemphyschem : a European journal of chemical physics and physical chemistry.
2004 Feb; 5(2):216-24. doi:
10.1002/cphc.200300947. [PMID: 15038282] - Masanori Yasuda, Kaoru Saito, Youichi Kobayashi, Toshinari Muramatsu, Tsuyoshi Miyamoto, Masaru Murakami, Takao Shinozuka, Bunpei Ishizuka, Tsunehisa Makino, Hiroshi Kajiwara, Robert Yoshiyuki Osamura. Serum carbohydrate antigen elevations in endometrial adenocarcinomas: characterization of DU-PAN-2 expression as a tumor marker.
The journal of obstetrics and gynaecology research.
2004 Feb; 30(1):59-64. doi:
10.1111/j.1341-8076.2004.00157.x. [PMID: 14718023] - Udo Jeschke, Ioannis Mylonas, Dagmar-Ulrike Richter, Annett Streu, Heiner Müller, Volker Briese, Klaus Friese. Human amniotic fluid glycoproteins expressing sialyl Lewis carbohydrate antigens stimulate progesterone production in human trophoblasts in vitro.
Gynecologic and obstetric investigation.
2004; 58(4):207-11. doi:
10.1159/000080073. [PMID: 15297810] - Kosei Nakajima, Hiroyoshi Ota, Mu Xia Zhang, Kenji Sano, Takayuki Honda, Keiko Ishii, Jun Nakayama. Expression of gastric gland mucous cell-type mucin in normal and neoplastic human tissues.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
2003 Dec; 51(12):1689-98. doi:
10.1177/002215540305101213. [PMID: 14623937] - Horst Schuldes, Daniel Schleicher, Gottfried Mayer, Bernd H Markus, Jindrich Cinatl, Roman A Blaheta. Binding of gastrointestinal tumor cells to endothelial E- and P-selectin adhesion receptors leads to transient down-regulation of sLeX ligands in vitro.
International journal of colorectal disease.
2003 Jul; 18(4):292-9. doi:
10.1007/s00384-002-0465-9. [PMID: 12774243] - Yutaka Shimada, Masato Maeda, Go Watanabe, Masayuki Imamura. High serum soluble E-selectin levels are associated with postoperative haematogenic recurrence in esophageal squamous cell carcinoma patients.
Oncology reports.
2003 Jul; 10(4):991-5. doi:
10.3892/or.10.4.991. [PMID: 12792758] - Udo Jeschke, Renate Stahn, Christoph Goletz, Xiaoyu Wang, Volker Briese, Klaus Friese. hCG in trophoblast tumour cells of the cell line Jeg3 and hCG isolated from amniotic fluid and serum of pregnant women carry oligosaccharides of the sialyl Lewis X and sialyl Lewis a type.
Anticancer research.
2003 Mar; 23(2A):1087-92. doi:
NULL. [PMID: 12820352] - Tsunehiro Oyama, Toshihiro Kawamoto, Koji Matsuno, Toshihiro Osaki, Akiko Matsumoto, Toyohi Isse, Shyouzi Nakata, Shinichi Ozaki, Masakazu Sugaya, Manabu Yasuda, Toshihiro Yamashita, Mitsuhiro Takenoyama, Kenji Sugio, Kosei Yasumoto. A case-case study comparing the usefulness of serum trace elements (Cu, Zn and Se) and tumor markers (CEA, SCC and SLX) in non-small cell lung cancer patients.
Anticancer research.
2003 Jan; 23(1B):605-12. doi:
NULL. [PMID: 12680155] - Michela Paganuzzi, Barbara Bobbio, Paola Marroni, Rosa Filiberti, Giovanni Battista Secco, Carlo Enrico Grossi. Prognostic role of serum sialyl Lewisx (CD15s) in colorectal cancer.
Oncology.
2003; 65(1):52-9. doi:
10.1159/000071205. [PMID: 12837983] - Fabio Fazio, Marian C Bryan, Ola Blixt, James C Paulson, Chi-Huey Wong. Synthesis of sugar arrays in microtiter plate.
Journal of the American Chemical Society.
2002 Dec; 124(48):14397-402. doi:
10.1021/ja020887u. [PMID: 12452714] - Takayuki Takubo, Hisako Shibata, Yoshiki Terada, Yasutaka Aoyama, Hirohisa Nakamae, Ryousuke Yamamura, Etsuko Shima, Kaori Makita, Kazuo Tanaka, Kensuke Ohta, Takahisa Yamane, Masayuki Hino, Shigemi Hashimoto, Tomio Kamitani, Noriyuki Tatsumi. Analysis of serum Sialyl-Lewis(x) antigen levels in acute leukemias, myelodysplastic syndromes, myeloproliferative disorders and malignant lymphomas.
Leukemia & lymphoma.
2002 Sep; 43(9):1889-91. doi:
10.1080/1042819021000006312. [PMID: 12685851] - Hideki Ishida, K Tanabe, T Tokumoto, H Shinmura, H Toma. Sialyl Lewis(x) monitoring as an early detector of B-cell-dependent rejection.
Transplantation proceedings.
2002 Aug; 34(5):1760-2. doi:
10.1016/s0041-1345(02)03057-9. [PMID: 12176566] - Mary L Alpaugh, James S Tomlinson, Sina Kasraeian, Sanford H Barsky. Cooperative role of E-cadherin and sialyl-Lewis X/A-deficient MUC1 in the passive dissemination of tumor emboli in inflammatory breast carcinoma.
Oncogene.
2002 May; 21(22):3631-43. doi:
10.1038/sj.onc.1205389. [PMID: 12032865] - Takuya Kanemitsu, Chi-Huey Wong, Osamu Kanie. Solid-phase synthesis of oligosaccharides and on-resin quantitative monitoring using gated decoupling (13)C NMR.
Journal of the American Chemical Society.
2002 Apr; 124(14):3591-9. doi:
10.1021/ja0167396. [PMID: 11929248] - Udo Bakowsky, Gabriele Schumacher, Christian Gege, Richard R Schmidt, Ulrich Rothe, Gerd Bendas. Cooperation between lateral ligand mobility and accessibility for receptor recognition in selectin-induced cell rolling.
Biochemistry.
2002 Apr; 41(14):4704-12. doi:
10.1021/bi0117596. [PMID: 11926833] - Tohru Nakagoe, Terumitsu Sawai, Takashi Tsuji, Masa-aki Jibiki, Atsushi Nanashima, Hiroyuki Yamaguchi, Toru Yasutake, Hiroyoshi Ayabe, Kokichi Arisawa, Hiroshi Ishikawa. Difference in prognostic value between sialyl Lewis(a) and sialyl Lewis(x) antigen levels in the preoperative serum of gastric cancer patients.
Journal of clinical gastroenterology.
2002 Apr; 34(4):408-15. doi:
10.1097/00004836-200204000-00005. [PMID: 11907351] - H Satoh, H Ishikawa, Y T Yamashita, M Ohtsuka, K Sekizawa. Serum sialyl Lewis X-i antigen in lung adenocarcinoma and idiopathic pulmonary fibrosis.
Thorax.
2002 Mar; 57(3):263-6. doi:
10.1136/thorax.57.3.263. [PMID: 11867833] - Christine Galustian, Robert A Childs, Mark Stoll, Hideharu Ishida, Makoto Kiso, Ten Feizi. Synergistic interactions of the two classes of ligand, sialyl-Lewis(a/x) fuco-oligosaccharides and short sulpho-motifs, with the P- and L-selectins: implications for therapeutic inhibitor designs.
Immunology.
2002 Mar; 105(3):350-9. doi:
10.1046/j.1365-2567.2002.01369.x. [PMID: 11918697] - Tohru Nakagoe, Terumitsu Sawai, Takashi Tsuji, Masa-Aki Jibiki, Atsushi Nanashima, Hiroyuki Yamaguchi, Toru Yasutake, Hiroyoshi Ayabe, Kokichi Arisawa, Hiroshi Ishikawa. Predictive factors for preoperative serum levels of sialy Lewis(x), sialyl Lewis(a) and sialyl Tn antigens in gastric cancer patients.
Anticancer research.
2002 Jan; 22(1A):451-8. doi:
NULL. [PMID: 12017332] - T Takubo, H Shibata, Y Terada, Y Aoyama, H Nakamae, R Yamamura, E Shima, K Makita, K Tanaka, K Ohta, T Yamane, M Hino, S Hashimoto, T Kamitani, N Tatsumi. Serum sialyl Lewis(x) levels in patients with various haematologic malignancies.
Haematologia.
2002; 32(2):147-9. doi:
10.1163/156855902320387989. [PMID: 12412734] - Masayoshi Takaeda, Hitoshi Yokoyama, Chikako Segawa-Takaeda, Takashi Wada, Ken-ichi Kobayashi. High endothelial venule-like vessels in the interstitial lesions of human glomerulonephritis.
American journal of nephrology.
2002 Jan; 22(1):48-57. doi:
10.1159/000046674. [PMID: 11919403] - S Bouyain, S Rushton, K Drickamer. Minimal requirements for the binding of selectin ligands to a C-type carbohydrate-recognition domain.
Glycobiology.
2001 Nov; 11(11):989-96. doi:
10.1093/glycob/11.11.989. [PMID: 11744633] - H Matsubayashi, K Kuraoka, Y Kobayashi, T Yokota, Y Iiri, K Shichijo, T Tada, K Satoh, H Kijima. Ruptured epidermoid cyst and haematoma of spleen: a diagnostic clue of high levels of serum carcinoembryonic antigen, carbohydrate antigen 19-9 and Sialyl Lewis x.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.
2001 Oct; 33(7):595-9. doi:
10.1016/s1590-8658(01)80114-6. [PMID: 11816551] - H Yamamoto, Y Miyake, S Noura, M Ogawa, M Yasui, M Ikenaga, M Sekimoto, M Monden. [Tumor markers for colorectal cancer].
Gan to kagaku ryoho. Cancer & chemotherapy.
2001 Sep; 28(9):1299-305. doi:
NULL. [PMID: 11579645] - I Ito, Y Yuzawa, M Mizuno, K Nishikawa, A Tashita, T Jomori, N Hotta, S Matsuo. Effects of a new synthetic selectin blocker in an acute rat thrombotic glomerulonephritis.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2001 Aug; 38(2):265-73. doi:
10.1053/ajkd.2001.26085. [PMID: 11479151] - S A Laucella, A Riarte, N Prado, J Zapata, E L Segura. alpha 4 Integrins and sialyl Lewis x modulation in chronic Chagas disease: further evidence of persistent immune activation.
Scandinavian journal of immunology.
2001 May; 53(5):514-9. doi:
10.1046/j.1365-3083.2001.00916.x. [PMID: 11309161] - H Hayashi, N Imanishi, M Ohnishi, S J Tojo. Sialyl Lewis X and anti-P-selectin antibody attenuate lipopolysaccharide-induced acute renal failure in rabbits.
Nephron.
2001 Apr; 87(4):352-60. doi:
10.1159/000045942. [PMID: 11287780] - T Nakagoe, T Sawai, T Tsuji, M Jibiki, A Nanashima, H Yamaguchi, N Kurosaki, T Yasutake, H Ayabe. Circulating sialyl Lewis(x), sialyl Lewis(a), and sialyl Tn antigens in colorectal cancer patients: multivariate analysis of predictive factors for serum antigen levels.
Journal of gastroenterology.
2001 Mar; 36(3):166-72. doi:
10.1007/s005350170124. [PMID: 11291879] - T Nakagoe, T Sawai, T Tsuji, M Jibiki, M Ohbatake, A Nanashima, H Yamaguchi, T Yasutake, H Ayabe, K Arisawa. Prognostic value of serum sialyl Lewis(a), sialyl Lewis(x) and sialyl Tn antigens in blood from the tumor drainage vein of colorectal cancer patients.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.
2001 Mar; 22(2):115-22. doi:
10.1159/000050605. [PMID: 11125284] - T Nakagoe, T Sawai, T Tsuji, M Jibiki, M Ohbatake, A Nanashima, H Yamaguchi, N Kurosaki, T Yasutake, H Ayabe, K Arisawa. Increased serum level of sialyl Lewis(x) antigen in blood from the tumor drainage vein in patients with non-polypoid growth type of colorectal cancer.
Journal of experimental & clinical cancer research : CR.
2001 Mar; 20(1):85-90. doi:
NULL. [PMID: 11370835] - R A Schmid, S Hillinger, J Hamacher, U Stammberger. TP20 is superior to TP10 in reducing ischemia/reperfusion injury in rat lung grafts.
Transplantation proceedings.
2001 Feb; 33(1-2):948-9. doi:
10.1016/s0041-1345(00)02279-x. [PMID: 11267139]
