4-Epidoxorubicinium (BioDeep_00001029714)
代谢物信息卡片
4-Epidoxorubicinium
化学式: C27H30NO11+ (544.181877)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)CO)O)[NH3+])O
InChI: InChI=1S/C27H29NO11/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3/p+1/t10-,13-,15-,17-,22-,27-/m0/s1
描述信息
An anthracycline cation resulting from the protonation of the amino group of 4-epidoxorubicin.
同义名列表
1 个代谢物同义名
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Ji'an He, Mei Li, Yan Xu, Ning Fan, Chong Tian, Tianye Lv, Wenge Xing, Haipeng Yu. In vitro characteristics of Epirubicin-loaded thermosensitive liquid embolic agent.
Journal of cancer research and therapeutics.
2023 Dec; 19(6):1597-1602. doi:
10.4103/jcrt.jcrt_334_23. [PMID: 38156927] - Solomon Owumi, Uche Arunsi, Moses Otunla, Grace Adebisi, Ahmad Altayyar, Chioma Irozuru. 3-Indolepropionic acid mitigates sub-acute toxicity in the cardiomyocytes of epirubicin-treated female rats.
Naunyn-Schmiedeberg's archives of pharmacology.
2023 Jul; ?(?):. doi:
10.1007/s00210-023-02618-y. [PMID: 37477660] - Shilin Tian, Yue Lu, Haifeng Gao, Zitong Chen, Min Niu, Changjun Wang, Bin Liu. Epirubicin may enhance the inhibition of hepatocellular carcinoma induced by iodine-125 seeds through downregulating WNT pathway.
Asia-Pacific journal of clinical oncology.
2023 Jun; 19(3):355-364. doi:
10.1111/ajco.13873. [PMID: 36464954] - Yu-Jia Wang, Ling Tang, Xu-Hong Lu, Ji-Tao Liu, Yuan-Yuan Wang, Hong-Xia Geng, Xue-Tao Li, Quan An. Efficacy of epi-1 modified epirubicin and curcumin encapsulated liposomes targeting-EpCAM in the inhibition of epithelial ovarian cancer cells.
Journal of liposome research.
2023 Jun; 33(2):197-213. doi:
10.1080/08982104.2022.2153138. [PMID: 36440599] - Solomon E Owumi, Grace Adebisi. Epirubicin Treatment Induces Neurobehavioral, Oxido-Inflammatory and Neurohistology Alterations in Rats: Protective Effect of the Endogenous Metabolite of Tryptophan - 3-Indolepropionic Acid.
Neurochemical research.
2023 Apr; ?(?):. doi:
10.1007/s11064-023-03941-9. [PMID: 37097396] - Gang Yuan, Yanneng Xu, Xiaopeng Bai, Weiming Wang, Xuan Wu, Jianli Chen, Jie Li, Xiaohui Jia, Zeyun Gu, Xun Zhang, Wei Hu, Jianfang Wang, Yong Liu, Xiao-Ming Zhu. Autophagy-Targeted Calcium Phosphate Nanoparticles Enable Transarterial Chemoembolization for Enhanced Cancer Therapy.
ACS applied materials & interfaces.
2023 Feb; ?(?):. doi:
10.1021/acsami.2c18267. [PMID: 36848495] - Hongli Yu, Jianqin Yan, Zhipeng Li, Tingting Song, Fang Ning, Jinshan Tan, Yong Sun. Enhanced photothermal-ferroptosis effects based on RBCm-coated PDA nanoparticles for effective cancer therapy.
Journal of materials chemistry. B.
2023 01; 11(2):415-429. doi:
10.1039/d2tb02329f. [PMID: 36512437] - Xiaofang Li, Xin Guo, Jun Li, Li Yuan, Haixiong Wang. Preventing effect of astragalus polysaccharide on cardiotoxicity induced by chemotherapy of epirubicin: A pilot study.
Medicine.
2022 Aug; 101(32):e30000. doi:
10.1097/md.0000000000030000. [PMID: 35960075] - Wei Ha, Jun-Li Yang, Yan-Ping Shi. Antibacterial metal-phenolic nanosheets as smart carriers for the controlled release of epirubicin hydrochloride.
Nanoscale.
2022 Jul; 14(27):9806-9817. doi:
10.1039/d2nr02066a. [PMID: 35770915] - Dehua Kong, Wenyu Hong, Miao Yu, Yanxia Li, YaXin Zheng, Xue Ying. Multifunctional Targeting Liposomes of Epirubicin Plus Resveratrol Improved Therapeutic Effect on Brain Gliomas.
International journal of nanomedicine.
2022; 17(?):1087-1110. doi:
10.2147/ijn.s346948. [PMID: 35313461] - Margarita Y Zhelyazkova, Nadya G Hristova-Avakumova, Georgi Tsv Momekov. Antitumor activity of the combination of artemisinin and epirubicin in human leukemia cells.
Folia medica.
2021 Aug; 63(4):488-495. doi:
10.3897/folmed.63.e55938. [PMID: 35851170] - Xue-Tao Li, Ming Jing, Fu-Yi Cai, Xue-Min Yao, Liang Kong, Xiao-Bo Wang. Enhanced antitumour efficiency of R8GD-modified epirubicin plus tetrandrine liposomes in treatment of gastric cancer via inhibiting tumour metastasis.
Journal of liposome research.
2021 Jun; 31(2):145-157. doi:
10.1080/08982104.2020.1748647. [PMID: 32223361] - Yi-Ting Lin, Xin-Yue Zheng, Yi-Fan Yao, Yu-Ying Zhang, Ting-Ting Huang, Yun-Lan Zhu, Jun Pei, Jin Wang, Ming Chu, Yue-Dan Wang. [Therapeutic Effect of Spleen Low Molecular Weight Extracts on Leukopenia Caused by Epirubicin in Mice and Its Mechanism].
Zhongguo shi yan xue ye xue za zhi.
2021 Jun; 29(3):969-974. doi:
10.19746/j.cnki.issn.1009-2137.2021.03.050. [PMID: 34105502] - Irisvan S Ribeiro, Francisco J G Pontes, Maria J M Carneiro, Nayara A Sousa, Vicente P T Pinto, Fábio O S Ribeiro, Durcilene A Silva, Gisele S Araújo, José D B Marinho Filho, Ana J Araújo, Haroldo C B Paula, Judith P A Feitosa, Regina C M de Paula. Poly(ε-caprolactone) grafted cashew gum nanoparticles as an epirubicin delivery system.
International journal of biological macromolecules.
2021 May; 179(?):314-323. doi:
10.1016/j.ijbiomac.2021.03.011. [PMID: 33675833] - Alessandro De Vita, Chiara Liverani, Roberto Molinaro, Jonathan O Martinez, Kelly A Hartman, Chiara Spadazzi, Giacomo Miserocchi, Francesca Taraballi, Michael Evangelopoulos, Federica Pieri, Alberto Bongiovanni, Laura Mercatali, Ennio Tasciotti, Toni Ibrahim. Lysyl oxidase engineered lipid nanovesicles for the treatment of triple negative breast cancer.
Scientific reports.
2021 03; 11(1):5107. doi:
10.1038/s41598-021-84492-3. [PMID: 33658580] - Balasubramani Gl, Rinky Rajput, Manish Gupta, Pradeep Dahiya, Jitendra K Thakur, Rakesh Bhatnagar, Abhinav Grover. Structure-based drug repurposing to inhibit the DNA gyrase of Mycobacterium tuberculosis.
The Biochemical journal.
2020 11; 477(21):4167-4190. doi:
10.1042/bcj20200462. [PMID: 33030198] - Junjie Li, Keda Yu, Da Pang, Changqin Wang, Jun Jiang, Suisheng Yang, Yunjiang Liu, Peifen Fu, Yuan Sheng, Guojun Zhang, Yali Cao, Qi He, Shude Cui, Xijing Wang, Guosheng Ren, Xinzheng Li, Shiyou Yu, Pengxi Liu, Xiang Qu, Jinhai Tang, Ouchen Wang, Zhimin Fan, Guoqin Jiang, Jin Zhang, Jiandong Wang, Hongwei Zhang, Shui Wang, Jianguo Zhang, Feng Jin, Nanyan Rao, Binlin Ma, Pingqing He, Binghe Xu, Zhigang Zhuang, Jianfeng Wang, Qiang Sun, Xiaofeng Guo, Miao Mo, Zhimin Shao. Adjuvant Capecitabine With Docetaxel and Cyclophosphamide Plus Epirubicin for Triple-Negative Breast Cancer (CBCSG010): An Open-Label, Randomized, Multicenter, Phase III Trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2020 06; 38(16):1774-1784. doi:
10.1200/jco.19.02474. [PMID: 32275467] - Ming Jing, Xiao-Jie Bi, Xue-Min Yao, Fuyi Cai, Jing-Jing Liu, Min Fu, Liang Kong, Xin-Ze Liu, Lu Zhang, Si-Yu He, Lian-Qun Jia, Xue-Tao Li. Enhanced antitumor efficacy using epirubicin and schisandrin B co-delivery liposomes modified with PFV via inhibiting tumor metastasis.
Drug development and industrial pharmacy.
2020 Apr; 46(4):621-634. doi:
10.1080/03639045.2020.1742145. [PMID: 32162988] - Liang Kong, Fu-Yi Cai, Xue-Min Yao, Ming Jing, Min Fu, Jing-Jing Liu, Si-Yu He, Lu Zhang, Xin-Ze Liu, Rui-Jun Ju, Xue-Tao Li. RPV-modified epirubicin and dioscin co-delivery liposomes suppress non-small cell lung cancer growth by limiting nutrition supply.
Cancer science.
2020 Feb; 111(2):621-636. doi:
10.1111/cas.14256. [PMID: 31777993] - Xiang Li, Qian Zou, Jing Zhang, Peng Zhang, Xiong Zhou, Satya Siva Kishan Yalamarty, Xinli Liang, Yali Liu, Qin Zheng, Jianqing Gao. Self-Assembled Dual-Targeted Epirubicin-Hybrid Polydopamine Nanoparticles for Combined Chemo-Photothermal Therapy of Triple-Negative Breast Cancer.
International journal of nanomedicine.
2020; 15(?):6791-6811. doi:
10.2147/ijn.s260477. [PMID: 32982234] - Jing-Jing Liu, Wei Tang, Min Fu, Xiao-Qing Gong, Liang Kong, Xue-Min Yao, Ming Jing, Fu-Yi Cai, Xue-Tao Li, Rui-Jun Ju. Development of R8 modified epirubicin-dihydroartemisinin liposomes for treatment of non-small-cell lung cancer.
Artificial cells, nanomedicine, and biotechnology.
2019 Dec; 47(1):1947-1960. doi:
10.1080/21691401.2019.1615932. [PMID: 31079495] - Ai Ch'i Liew, Kok-Khiang Peh, Boon Seang Tan, Wei Zhao, Balamurugan Tangiisuran. Evaluation of chemotherapy-induced toxicity and health-related quality of life amongst early-stage breast cancer patients receiving Chinese herbal medicine in Malaysia.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer.
2019 Dec; 27(12):4515-4524. doi:
10.1007/s00520-019-04724-1. [PMID: 30911917] - Neng Wang, Bowen Yang, Gulizeba Muhetaer, Shengqi Wang, Yifeng Zheng, Jiahong Lu, Min Li, Fengxue Zhang, Honglin Situ, Yi Lin, Zhiyu Wang. XIAOPI formula promotes breast cancer chemosensitivity via inhibiting CXCL1/HMGB1-mediated autophagy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2019 Dec; 120(?):109519. doi:
10.1016/j.biopha.2019.109519. [PMID: 31629951] - Xu Jing, Chao Sun, Huigang Chen, Jing Sun, Ying Zhang, Jing Wu. Protection of paeonol against epirubicin-induced hepatotoxicity: A metabolomic study.
Bioscience trends.
2019 Jul; 13(3):253-260. doi:
10.5582/bst.2019.01105. [PMID: 31231109] - Fengyi Guo, Tian Xia, Yedan Zhang, Xiaotong Ma, Zhongrui Yan, Shaohua Hao, Yali Han, Ruihong Ma, Yuan Zhou, Xue Du. Menstrual blood derived mesenchymal stem cells combined with Bushen Tiaochong recipe improved chemotherapy-induced premature ovarian failure in mice by inhibiting GADD45b expression in the cell cycle pathway.
Reproductive biology and endocrinology : RB&E.
2019 Jul; 17(1):56. doi:
10.1186/s12958-019-0499-2. [PMID: 31311554] - Ean-Jeong Seo, Sabine M Klauck, Thomas Efferth, Alexander Panossian. Adaptogens in chemobrain (Part II): Effect of plant extracts on chemotherapy-induced cytotoxicity in neuroglia cells.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2019 May; 58(?):152743. doi:
10.1016/j.phymed.2018.11.004. [PMID: 30901664] - Ean-Jeong Seo, Sabine M Klauck, Thomas Efferth, Alexander Panossian. Adaptogens in chemobrain (Part I): Plant extracts attenuate cancer chemotherapy-induced cognitive impairment - Transcriptome-wide microarray profiles of neuroglia cells.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2019 Mar; 55(?):80-91. doi:
10.1016/j.phymed.2018.10.022. [PMID: 30668446] - Xiaoyun Song, Xiqiu Zhou, Yuenong Qin, Jianfeng Yang, Yu Wang, Zhenping Sun, Kui Yu, Shuai Zhang, Sheng Liu. Emodin inhibits epithelial‑mesenchymal transition and metastasis of triple negative breast cancer via antagonism of CC‑chemokine ligand 5 secreted from adipocytes.
International journal of molecular medicine.
2018 Jul; 42(1):579-588. doi:
10.3892/ijmm.2018.3638. [PMID: 29693154] - Fangfang Shi, Miao Li, Jing Wang, Di Wu, Meng Pan, Mei Guo, Jun Dou. Induction of multiple myeloma cancer stem cell apoptosis using conjugated anti-ABCG2 antibody with epirubicin-loaded microbubbles.
Stem cell research & therapy.
2018 05; 9(1):144. doi:
10.1186/s13287-018-0885-2. [PMID: 29784015] - Miao Yu, Shangcong Han, Zhongai Kou, Jialing Dai, Jiao Liu, Chen Wei, Yitong Li, Lutao Jiang, Yong Sun. Lipid nanoparticle-based co-delivery of epirubicin and BCL-2 siRNA for enhanced intracellular drug release and reversing multidrug resistance.
Artificial cells, nanomedicine, and biotechnology.
2018 Mar; 46(2):323-332. doi:
10.1080/21691401.2017.1307215. [PMID: 28393563] - Mingzi Zhang, Zhongkai Tian, Yehong Sun. Successful treatment of ovarian cancer with apatinib combined with chemotherapy: A case report.
Medicine.
2017 Nov; 96(45):e8570. doi:
10.1097/md.0000000000008570. [PMID: 29137078] - Yuxiao Yao, Shaoyang Sun, Fei Fei, Jingjing Wang, Youhua Wang, Ranran Zhang, Jing Wu, Lian Liu, Xiuyun Liu, Zhaomeng Cui, Qiang Li, Min Yu, Yongjun Dang, Xu Wang. Screening in larval zebrafish reveals tissue-specific distribution of fifteen fluorescent compounds.
Disease models & mechanisms.
2017 09; 10(9):1155-1164. doi:
10.1242/dmm.028811. [PMID: 28754836] - A M Eltweri, A L Thomas, H L Fisk, A Arshad, P C Calder, A R Dennison, D J Bowrey. Plasma and erythrocyte uptake of omega-3 fatty acids from an intravenous fish oil based lipid emulsion in patients with advanced oesophagogastric cancer.
Clinical nutrition (Edinburgh, Scotland).
2017 06; 36(3):768-774. doi:
10.1016/j.clnu.2016.06.001. [PMID: 27342748] - Gang Chen, Ding Zhang, Yacao Ying, Zhifeng Wang, Wei Tao, Hao Zhu, Jingfeng Zhang, Zhiyi Peng. [Clinical investigation on transarterial chemoembolization with indigenous drug-eluting beads in treatment of unresectable hepatocellular carcinoma].
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences.
2017 01; 46(1):44-51. doi:
10.3785/j.issn.1008-9292.2017.02.07. [PMID: 28436630] - Xiao-Li Song, Rui-Jun Ju, Yao Xiao, Xin Wang, Shuang Liu, Min Fu, Jing-Jing Liu, Li-Yan Gu, Xue-Tao Li, Lan Cheng. Application of multifunctional targeting epirubicin liposomes in the treatment of non-small-cell lung cancer.
International journal of nanomedicine.
2017; 12(?):7433-7451. doi:
10.2147/ijn.s141787. [PMID: 29066893] - Clara M W S Abreu, Haroldo C B Paula, Vitor Seabra, Judith P A Feitosa, Bruno Sarmento, Regina C M de Paula. Synthesis and characterization of non-toxic and thermo-sensitive poly(N-isopropylacrylamide)-grafted cashew gum nanoparticles as a potential epirubicin delivery matrix.
Carbohydrate polymers.
2016 Dec; 154(?):77-85. doi:
10.1016/j.carbpol.2016.08.031. [PMID: 27577899] - Hui Li, Yiqing Mao, Qun Zhang, Qing Han, Zhenming Man, Jingyu Zhang, Xi Wang, Ruobi Hu, Xuehui Zhang, David M Irwin, Gang Niu, Huanran Tan. Xinmailong mitigated epirubicin-induced cardiotoxicity via inhibiting autophagy.
Journal of ethnopharmacology.
2016 Nov; 192(?):459-470. doi:
10.1016/j.jep.2016.08.031. [PMID: 27586823] - Hou-Pan Song, Ru-Liu Li, Yi-Yu Wang, Xiao-Hua Tu, Jiao Deng, Wei-Wen Chen. [Effects of Methanol Extracts from Atractylodes macrocephalae Rhizoma on Small Intestinal Epi- thelial Cell Proliferation and Migration, and Expression of Phospholipase C-γl].
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
2016 07; 36(7):861-866. doi:
. [PMID: 30634216] - Li-han Zhang, Ai-jun Yang, Min Wang, Wei Liu, Chen-yu Wang, Xiao-feng Xie, Xu Chen, Jing-fei Dong, Min Li. Enhanced autophagy reveals vulnerability of P-gp mediated epirubicin resistance in triple negative breast cancer cells.
Apoptosis : an international journal on programmed cell death.
2016 Apr; 21(4):473-88. doi:
10.1007/s10495-016-1214-9. [PMID: 26767845] - Monika Sharma, Jo Tuaine, Blair McLaren, Debra L Waters, Katherine Black, Lynnette M Jones, Sally P A McCormick. Chemotherapy Agents Alter Plasma Lipids in Breast Cancer Patients and Show Differential Effects on Lipid Metabolism Genes in Liver Cells.
PloS one.
2016; 11(1):e0148049. doi:
10.1371/journal.pone.0148049. [PMID: 26807857] - Takaaki Yamada, Mitsuyo Ueda, Nobuaki Egashira, Nina Zukeyama, Jun Kuwahara, Satohiro Masuda. Involvement of intracellular cAMP in epirubicin-induced vascular endothelial cell injury.
Journal of pharmacological sciences.
2016 Jan; 130(1):33-7. doi:
10.1016/j.jphs.2015.12.010. [PMID: 26809377] - Fangfang Shi, Fang Yang, Xiangfeng He, Ying Zhang, Songyan Wu, Miao Li, Yunxia Zhang, Wu Di, Jun Dou, Ning Gu. Inhibitory effect of epirubicin-loaded lipid microbubbles with conjugated anti-ABCG2 antibody combined with therapeutic ultrasound on multiple myeloma cancer stem cells.
Journal of drug targeting.
2016; 24(1):34-46. doi:
10.3109/1061186x.2015.1052075. [PMID: 26204324] - Jun Li, Qing Wang, Zhengqing Lei, Dong Wu, Anfeng Si, Kui Wang, Xuying Wan, Yizhou Wang, Zhenlin Yan, Yong Xia, Wan Yee Lau, Mengchao Wu, Feng Shen. Adjuvant Transarterial Chemoembolization Following Liver Resection for Intrahepatic Cholangiocarcinoma Based on Survival Risk Stratification.
The oncologist.
2015 Jun; 20(6):640-7. doi:
10.1634/theoncologist.2014-0470. [PMID: 25956404] - Magda Nasr, Noha Nafee, Hoda Saad, Amani Kazem. Improved antitumor activity and reduced cardiotoxicity of epirubicin using hepatocyte-targeted nanoparticles combined with tocotrienols against hepatocellular carcinoma in mice.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2014 Sep; 88(1):216-25. doi:
10.1016/j.ejpb.2014.04.016. [PMID: 24813390] - Rui-Jun Ju, Xue-Tao Li, Ji-Feng Shi, Xiu-Ying Li, Meng-Ge Sun, Fan Zeng, Jia Zhou, Lei Liu, Cheng-Xiang Zhang, Wei-Yu Zhao, Wan-Liang Lu. Liposomes, modified with PTD(HIV-1) peptide, containing epirubicin and celecoxib, to target vasculogenic mimicry channels in invasive breast cancer.
Biomaterials.
2014 Aug; 35(26):7610-21. doi:
10.1016/j.biomaterials.2014.05.040. [PMID: 24912818] - Halide Hamat-Mecbur, Sibel Yilmaz, Aslihan Temel, Kaniye Sahin, Nermin Gozukirmizi. Effects of epirubicin on barley seedlings.
Toxicology and industrial health.
2014 Feb; 30(1):52-9. doi:
10.1177/0748233712451768. [PMID: 22722775] - Wen Liu, Fang-Fang Gao, Qun Li, Jia-Wei Lv, Ying Wang, Peng-Chao Hu, Qing-Ming Xiang, Lei Wei. Protective effect of astragalus polysaccharides on liver injury induced by several different chemotherapeutics in mice.
Asian Pacific journal of cancer prevention : APJCP.
2014; 15(23):10413-20. doi:
10.7314/apjcp.2014.15.23.10413. [PMID: 25556485] - A Alacacioglu, L Kebapcilar, B Onder Pamuk, G Sop, C Kucukiravul, G Bozkaya, A Yuksel, I Alacacioglu, I Sari. Oxidative and antioxidative status after anthracyclinebased chemotherapy in breast cancer patients.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology.
2013 Jul; 18(3):614-8. doi:
NULL. [PMID: 24065472] - Keng-Shiang Huang, Chih-Yu Wang, Chih-Hui Yang, Alexandru Mihai Grumezescu, Yung-Sheng Lin, Chao-Pin Kung, I-Yin Lin, Yi-Ching Chang, Wei-Jie Weng, Wei-Ting Wang. Synthesis and characterization of oil-chitosan composite spheres.
Molecules (Basel, Switzerland).
2013 May; 18(5):5749-60. doi:
10.3390/molecules18055749. [PMID: 23681059] - Chi-Chen Lu, Mei-Yi Lin, Syue-Yi Chen, Cheng-Huang Shen, Lih-Geeng Chen, Hsiao-Yen Hsieh, Michael W Y Chan, Cheng-Da Hsu. The investigation of a traditional Chinese medicine, Guizhi Fuling Wan (GFW) as an intravesical therapeutic agent for urothelial carcinoma of the bladder.
BMC complementary and alternative medicine.
2013 Feb; 13(?):44. doi:
10.1186/1472-6882-13-44. [PMID: 23433042] - Dominik Lipka, Jerzy Gubernator, Nina Filipczak, Sabine Barnert, Regine Süss, Mateusz Legut, Arkadiusz Kozubek. Vitamin C-driven epirubicin loading into liposomes.
International journal of nanomedicine.
2013; 8(?):3573-85. doi:
10.2147/ijn.s47745. [PMID: 24101870] - HanJie Wang, Wenya Su, Sheng Wang, Xiaomin Wang, Zhenyu Liao, Chunsheng Kang, Lei Han, Jin Chang, Guangxiu Wang, Peiyu Pu. Smart multifunctional core-shell nanospheres with drug and gene co-loaded for enhancing the therapeutic effect in a rat intracranial tumor model.
Nanoscale.
2012 Oct; 4(20):6501-8. doi:
10.1039/c2nr31263h. [PMID: 22961067] - Nawale Hajjaji, Pierre Besson, Philippe Bougnoux. Tumor and non-tumor tissues differential oxidative stress response to supplemental DHA and chemotherapy in rats.
Cancer chemotherapy and pharmacology.
2012 Jul; 70(1):17-23. doi:
10.1007/s00280-012-1884-0. [PMID: 22610354] - Sefedin Biljali, Vera A Hadjimitova, Margarita N Topashka-Ancheva, Denitsa B Momekova, Trayko T Traykov, Margarita H Karaivanova. Antioxidant and antiradical properties of esculin, and its effect in a model of epirubicin-induced bone marrow toxicity.
Folia medica.
2012 Jul; 54(3):42-9. doi:
10.2478/v10153-011-0096-4. [PMID: 23270206] - Hua Zhang, Wei-sheng Shen, Chun-heng Gao, Li-chun Deng, Dong Shen. Protective effects of salidroside on epirubicin-induced early left ventricular regional systolic dysfunction in patients with breast cancer.
Drugs in R&D.
2012 Jun; 12(2):101-6. doi:
10.2165/11632530-000000000-00000. [PMID: 22770377] - Christian Henninger, Johannes Huelsenbeck, Stefanie Huelsenbeck, Sabine Grösch, Arno Schad, Karl J Lackner, Bernd Kaina, Gerhard Fritz. The lipid lowering drug lovastatin protects against doxorubicin-induced hepatotoxicity.
Toxicology and applied pharmacology.
2012 May; 261(1):66-73. doi:
10.1016/j.taap.2012.03.012. [PMID: 22712078] - Takaaki Yamada, Nobuaki Egashira, Ayami Bando, Yui Nishime, Yuki Tonogai, Maiko Imuta, Takahisa Yano, Ryozo Oishi. Activation of p38 MAPK by oxidative stress underlying epirubicin-induced vascular endothelial cell injury.
Free radical biology & medicine.
2012 Apr; 52(8):1285-93. doi:
10.1016/j.freeradbiomed.2012.02.003. [PMID: 22330067] - Ling Xu, Xiujuan Qu, Ying Luo, Ye Zhang, Jing Liu, Jinglei Qu, Lingyun Zhang, Yunpeng Liu. Epirubicin enhances TRAIL-induced apoptosis in gastric cancer cells by promoting death receptor clustering in lipid rafts.
Molecular medicine reports.
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