1-cyclopropyl-6-fluoro-8-methoxy-7-[(3S)-3-methylpiperazin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (BioDeep_00001029568)
代谢物信息卡片
1-cyclopropyl-6-fluoro-8-methoxy-7-[(3S)-3-methylpiperazin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
化学式: C19H22FN3O4 (375.15942640000003)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1CN(CCN1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F
InChI: InChI=1S/C19H22FN3O4/c1-10-8-22(6-5-21-10)16-14(20)7-12-15(18(16)27-2)23(11-3-4-11)9-13(17(12)24)19(25)26/h7,9-11,21H,3-6,8H2,1-2H3,(H,25,26)/t10-/m0/s1
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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Plant Reactome(0)
INOH(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
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文献列表
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2007 Dec; 3(6):869-97. doi:
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Veterinary research communications.
2007 Nov; 31(8):1013-20. doi:
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Se pu = Chinese journal of chromatography.
2007 Nov; 25(6):930-3. doi:
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Pharmacotherapy.
2007 Nov; 27(11):1498-505. doi:
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Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.
2007 Sep; 23(9):1053-8. doi:
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Diagnostic microbiology and infectious disease.
2007 Sep; 59(1):67-74. doi:
10.1016/j.diagmicrobio.2007.04.015. [PMID: 17875453] - Kausik K Ray, David A Morrow, Marc S Sabatine, Amy Shui, Nader Rifai, Christopher P Cannon, Eugene Braunwald. Long-term prognostic value of neopterin: a novel marker of monocyte activation in patients with acute coronary syndrome.
Circulation.
2007 Jun; 115(24):3071-8. doi:
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Current medical research and opinion.
2007 Jun; 23(6):1403-13. doi:
10.1185/030079907x188099. [PMID: 17559736] - Douglas N Fish. Evaluation of gatifloxacin pharmacokinetics and pharmacodynamics in severely ill adults in a medical Intensive Care Unit.
International journal of antimicrobial agents.
2007 Jun; 29(6):715-23. doi:
10.1016/j.ijantimicag.2007.02.006. [PMID: 17433631] - Leandro Tasso, Teresa Dalla Costa. High performance liquid chromatography for quantification of gatifloxacin in rat plasma following automated on-line solid phase extraction.
Journal of pharmaceutical and biomedical analysis.
2007 May; 44(1):205-10. doi:
10.1016/j.jpba.2007.02.026. [PMID: 17403594] - Shin-Ichi Maeda, Masayoshi Tamaki, Yasuaki Kubota, Phuoc Ba Nguyen, Mitsuru Yasuda, Takashi Deguchi. Treatment of men with urethritis negative for Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma parvum and Ureaplasma urealyticum.
International journal of urology : official journal of the Japanese Urological Association.
2007 May; 14(5):422-5. doi:
10.1111/j.1442-2042.2007.01750.x. [PMID: 17511725] - Mudjalin Ovartlarnporn, Wallaya Jongjaroenprasert. Advancing age and renal impairment as important predisposing factors of gatifloxacin-induced hyperglycemia in non-diabetes patients.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet.
2007 Mar; 90(3):569-73. doi:
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2007 Feb; 846(1-2):306-12. doi:
10.1016/j.jchromb.2006.09.022. [PMID: 17027349] - Junko Kikuchi, Koichi Yamazaki, Eiki Kikuchi, Akitoshi Ishizaka, Masaharu Nishimura. Pharmacokinetics of gatifloxacin after a single oral dose in healthy young adult subjects and adult patients with chronic bronchitis, with a comparison of drug concentrations obtained by bronchoscopic microsampling and bronchoalveolar lavage.
Clinical therapeutics.
2007 Jan; 29(1):123-30. doi:
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International journal of clinical pharmacology and therapeutics.
2007 Jan; 45(1):63-70. doi:
10.5414/cpp45063. [PMID: 17256452] - Dorota Wultańska, Piotr Obuch-Woszczatyński, Hanna Pituch, Mirosław Luczak. [Survey of susceptibility of clinical Clostridium diffiicile strains isolated from patients hospitalised in different departments of paediatric hospital to antimicrobial agents].
Medycyna doswiadczalna i mikrobiologia.
2007; 59(2):161-8. doi:
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Clinical therapeutics.
2006 Nov; 28(11):1857-66. doi:
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Pakistan journal of pharmaceutical sciences.
2006 Oct; 19(4):275-81. doi:
NULL. [PMID: 17105703] - Shaheeda Ahmed, Christopher P Cannon, Sabina A Murphy, Eugene Braunwald. Acute coronary syndromes and diabetes: Is intensive lipid lowering beneficial? Results of the PROVE IT-TIMI 22 trial.
European heart journal.
2006 Oct; 27(19):2323-9. doi:
10.1093/eurheartj/ehl220. [PMID: 16954134] - Xin Zhang, Brian R Overholser, Michael B Kays, Kevin M Sowinski. Gatifloxacin pharmacokinetics in healthy men and women.
Journal of clinical pharmacology.
2006 Oct; 46(10):1154-62. doi:
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Archives of physical medicine and rehabilitation.
2006 Oct; 87(10):1305-9. doi:
10.1016/j.apmr.2006.07.260. [PMID: 17023238] - Koji Hatano, Mototaka Sato, Yuichi Tsujimoto, Tsuyoshi Takada, Masato Honda, Kiyomi Matsumiya, Tetsu Mizutani, Hideki Fujioka. [Pyogenic spondylitis by Enterobacter cloacae as a postoperative complication of TURP: a case report].
Hinyokika kiyo. Acta urologica Japonica.
2006 Aug; 52(8):641-4. doi:
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Journal of thrombosis and thrombolysis.
2006 Aug; 22(1):71-6. doi:
10.1007/s11239-006-8081-0. [PMID: 16786236] - Saleh Al-Dgither, Syed Naseeruddin Alvi, Muhammad M Hammami. Development and validation of an HPLC method for the determination of gatifloxacin stability in human plasma.
Journal of pharmaceutical and biomedical analysis.
2006 Apr; 41(1):251-5. doi:
10.1016/j.jpba.2005.09.026. [PMID: 16311002] - Seiji Hori, Junko Kizu, Masahiro Kawamura. Effect of fluoroquinolones on plasma glucose levels in fasted and glucose-loaded mice.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.
2006 Apr; 12(2):109-11. doi:
10.1007/s10156-006-0429-z. [PMID: 16648952] - Andreas Heinze, Ulrike Holzgrabe. Determination of the extent of protein binding of antibiotics by means of an automated continuous ultrafiltration method.
International journal of pharmaceutics.
2006 Mar; 311(1-2):108-12. doi:
10.1016/j.ijpharm.2005.12.022. [PMID: 16431044] - Yasuyoshi Ishiwata, Yasuaki Sanada, Masato Yasuhara. Effects of gatifloxacin on serum glucose concentration in normal and diabetic rats.
Biological & pharmaceutical bulletin.
2006 Mar; 29(3):527-31. doi:
10.1248/bpb.29.527. [PMID: 16508159] - Craig M Straley, Eric J Cecil, Mark P Herriman. Gatifloxacin interference with opiate urine drug screen.
Pharmacotherapy.
2006 Mar; 26(3):435-9. doi:
10.1592/phco.26.3.435. [PMID: 16503726] - Lauren A Beste, Tracey L Mersfelder. Hyperglycemia and gatifloxacin: a case report and summary of current literature.
The American journal of geriatric pharmacotherapy.
2005 Dec; 3(4):262-5. doi:
10.1016/j.amjopharm.2005.12.004. [PMID: 16503322] - Romi Bhasin, Francis Clifford Arce, Rosemarie Pasmantier. Hypoglycemia associated with the use of gatifloxacin.
The American journal of the medical sciences.
2005 Nov; 330(5):250-3. doi:
10.1097/00000441-200511000-00010. [PMID: 16284487] - Michael B Kays, Brian R Overholser, Seema Lagvankar, Mitchell Goldman, Kevin M Sowinski. Effect of ensure on the oral bioavailability of gatifloxacin in healthy volunteers.
Pharmacotherapy.
2005 Nov; 25(11):1530-5. doi:
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Pharmacotherapy.
2005 Oct; 25(10):1303-9. doi:
10.1592/phco.2005.25.10.1303. [PMID: 16185173] - Fei Tan, Ming Guo, QinSen Yu. Studies on interaction between gatifloxacin and human serum albumin as well as effect of copper(II) on the reaction.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2005 Oct; 61(13-14):3006-12. doi:
10.1016/j.saa.2004.11.019. [PMID: 16165044] - M A El Ries, A A Wassel, N T Abdel Ghani, M A El-Shall. Electrochemical adsorptive behavior of some fluoroquinolones at carbon paste electrode.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.
2005 Oct; 21(10):1249-54. doi:
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The Annals of pharmacotherapy.
2005 Jul; 39(7-8):1349-52. doi:
10.1345/aph.1e679. [PMID: 15941822]