Hydrogen (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetato(4-))gadolinate(1-) (BioDeep_00001028940)

   


代谢物信息卡片


Hydrogen (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetato(4-))gadolinate(1-)

化学式: C16H24GdN4O8- (558.0835174)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1CN(CCN(CCN(CCN1CC(=O)[O-])CC(=O)[O-])CC(=O)[O-])CC(=O)[O-].[Gd+3]
InChI: /q

描述信息

V - Various > V08 - Contrast media > V08C - Magnetic resonance imaging contrast media > V08CA - Paramagnetic contrast media
D064449 - Sequestering Agents > D002614 - Chelating Agents

同义名列表

1 个代谢物同义名

Hydrogen (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetato(4-))gadolinate(1-)



数据库引用编号

2 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Fatemeh Maghsoudinia, Hadi Akbari-Zadeh, Fahimeh Aminolroayaei, Fariba Farhadi Birgani, Ahmad Shanei, Roghayeh Kamran Samani. Ultrasound responsive Gd-DOTA/doxorubicin-loaded nanodroplet as a theranostic agent for magnetic resonance image-guided controlled release drug delivery of melanoma cancer. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2022 Jul; 174(?):106207. doi: 10.1016/j.ejps.2022.106207. [PMID: 35577179]
  • Janine Contro, Danilo Antonio Silva, Oscar A N Santisteban, Ponnada A Narayana, José G Nery. In vitro and in vivo comparative performance studies of gadolinium-loaded zeolites and Gd-DOTA as contrast agents for MRI applications. Journal of biomedical materials research. Part B, Applied biomaterials. 2021 08; 109(8):1105-1115. doi: 10.1002/jbm.b.34773. [PMID: 33283412]
  • Kosaku Yano, Tomohiro Matsumoto, Yutaka Okamoto, Naruki Kurokawa, Terumitsu Hasebe, Atsushi Hotta. Fabrication of Gd-DOTA-functionalized carboxylated nanodiamonds for selective MR imaging (MRI) of the lymphatic system. Nanotechnology. 2021 Mar; 32(23):. doi: 10.1088/1361-6528/abeb9c. [PMID: 33657547]
  • Sébastien Jenni, Frédéric Bolze, Célia S Bonnet, Agnès Pallier, Angélique Sour, Éva Tóth, Barbara Ventura, Valérie Heitz. Synthesis and In Vitro Studies of a Gd(DOTA)-Porphyrin Conjugate for Combined MRI and Photodynamic Treatment. Inorganic chemistry. 2020 Oct; 59(19):14389-14398. doi: 10.1021/acs.inorgchem.0c02189. [PMID: 32960580]
  • Sean A Woolen, Prasad R Shankar, Joel J Gagnier, Mark P MacEachern, Lisa Singer, Matthew S Davenport. Risk of Nephrogenic Systemic Fibrosis in Patients With Stage 4 or 5 Chronic Kidney Disease Receiving a Group II Gadolinium-Based Contrast Agent: A Systematic Review and Meta-analysis. JAMA internal medicine. 2020 02; 180(2):223-230. doi: 10.1001/jamainternmed.2019.5284. [PMID: 31816007]
  • Tianze Wu, Jian Zhang, Qiaomei Jin, Meng Gao, Dongjian Zhang, Libang Zhang, Yuanbo Feng, Yicheng Ni, Zhiqi Yin. Rhein-based necrosis-avid MRI contrast agents for early evaluation of tumor response to microwave ablation therapy. Magnetic resonance in medicine. 2019 12; 82(6):2212-2224. doi: 10.1002/mrm.27887. [PMID: 31418484]
  • Derek J Erstad, Ian A Ramsay, Veronica Clavijo Jordan, Mozhdeh Sojoodi, Bryan C Fuchs, Kenneth K Tanabe, Peter Caravan, Eric M Gale. Tumor Contrast Enhancement and Whole-Body Elimination of the Manganese-Based Magnetic Resonance Imaging Contrast Agent Mn-PyC3A. Investigative radiology. 2019 11; 54(11):697-703. doi: 10.1097/rli.0000000000000593. [PMID: 31356382]
  • Pavol Szomolanyi, Martin Rohrer, Thomas Frenzel, Iris M Noebauer-Huhmann, Gregor Jost, Jan Endrikat, Siegfried Trattnig, Hubertus Pietsch. Comparison of the Relaxivities of Macrocyclic Gadolinium-Based Contrast Agents in Human Plasma at 1.5, 3, and 7 T, and Blood at 3 T. Investigative radiology. 2019 09; 54(9):559-564. doi: 10.1097/rli.0000000000000577. [PMID: 31124800]
  • Achmad Adhipatria Perayabangsa Kartamihardja, Hirofumi Hanaoka, Putri Andriana, Satomi Kameo, Ayako Takahashi, Hiroshi Koyama, Yoshito Tsushima. Quantitative analysis of Gd in the protein content of the brain following single injection of gadolinium-based contrast agents (GBCAs) by size exclusion chromatography. The British journal of radiology. 2019 Jul; 92(1099):20190062. doi: 10.1259/bjr.20190062. [PMID: 31045442]
  • Jian Wang, Shaun S Kumar, Catherine M Sherwin, Robert Ward, Gerri Baer, Gilbert J Burckart, Yaning Wang, Lynne P Yao. Renal Clearance in Newborns and Infants: Predictive Performance of Population-Based Modeling for Drug Development. Clinical pharmacology and therapeutics. 2019 06; 105(6):1462-1470. doi: 10.1002/cpt.1332. [PMID: 30565653]
  • Nathalie Fretellier, Agnès Granottier, Marlène Rasschaert, Anne-Laure Grindel, Fannie Baudimont, Philippe Robert, Jean-Marc Idée, Claire Corot. Does Age Interfere With Gadolinium Toxicity and Presence in Brain and Bone Tissues?: A Comparative Gadoterate Versus Gadodiamide Study in Juvenile and Adult Rats. Investigative radiology. 2019 02; 54(2):61-71. doi: 10.1097/rli.0000000000000517. [PMID: 30394964]
  • Fatma Beyazal Celiker, Levent Tumkaya, Tolga Mercantepe, Mehmet Beyazal, Arzu Turan, Hatice Beyazal Polat, Zehra Topal Suzan, Mehmet Fatih Inecikli, Kerimali Akyildiz, Adnan Yilmaz. Effects of Gadodiamide and Gadoteric Acid on Rat Kidneys: A Comparative Study. Journal of magnetic resonance imaging : JMRI. 2019 02; 49(2):382-389. doi: 10.1002/jmri.26266. [PMID: 30209850]
  • A S Pitek, H Hu, S Shukla, N F Steinmetz. Cancer Theranostic Applications of Albumin-Coated Tobacco Mosaic Virus Nanoparticles. ACS applied materials & interfaces. 2018 Nov; 10(46):39468-39477. doi: 10.1021/acsami.8b12499. [PMID: 30403330]
  • Li Bian, Meng Gao, Dongjian Zhang, Aiyan Ji, Chang Su, Xinghua Duan, Qi Luo, Dejian Huang, Yuanbo Feng, Yicheng Ni, Zhiqi Yin, Qiaomei Jin, Jian Zhang. Synthesis and Biological Evaluation of Rhein-Based MRI Contrast Agents for in Vivo Visualization of Necrosis. Analytical chemistry. 2018 11; 90(22):13249-13256. doi: 10.1021/acs.analchem.8b01868. [PMID: 30379067]
  • Stéphane Demine, Alexander Balhuizen, Vinciane Debaille, Lieke Joosten, Maïté Fereau, Satya Narayana Murthy Chilla, Isabelle Millard, Raphaël Scharfmann, Dominique Egrise, Serge Goldman, Piero Marchetti, Martin Gotthardt, Sophie Laurent, Carmen Burtea, Decio L Eizirik. Imaging of Human Insulin Secreting Cells with Gd-DOTA-P88, a Paramagnetic Contrast Agent Targeting the Beta Cell Biomarker FXYD2γa. Molecules (Basel, Switzerland). 2018 Aug; 23(9):. doi: 10.3390/molecules23092100. [PMID: 30134599]
  • Simona Bussi, Alessandra Coppo, Catherine Botteron, Valérie Fraimbault, Antonello Fanizzi, Elisa De Laurentiis, Sonia Colombo Serra, Miles A Kirchin, Fabio Tedoldi, Federico Maisano. Differences in gadolinium retention after repeated injections of macrocyclic MR contrast agents to rats. Journal of magnetic resonance imaging : JMRI. 2018 03; 47(3):746-752. doi: 10.1002/jmri.25822. [PMID: 28730643]
  • Nina Pfannkuchen, Nicole Bausbacher, Stefanie Pektor, Matthias Miederer, Frank Rosch. In vivo Evaluation of [225Ac]Ac-DOTAZOL for α-Therapy of Bone Metastases. Current radiopharmaceuticals. 2018; 11(3):223-230. doi: 10.2174/1874471011666180604083911. [PMID: 29866026]
  • Duc H T Le, He Hu, Ulrich Commandeur, Nicole F Steinmetz. Chemical addressability of potato virus X for its applications in bio/nanotechnology. Journal of structural biology. 2017 12; 200(3):360-368. doi: 10.1016/j.jsb.2017.06.006. [PMID: 28647539]
  • Alberto Fringuello Mingo, Sonia Colombo Serra, Simona Baroni, Claudia Cabella, Roberta Napolitano, Ivan Hawala, Irene Maria Carnovale, Luciano Lattuada, Fabio Tedoldi, Silvio Aime. Macrocyclic paramagnetic agents for MRI: Determinants of relaxivity and strategies for their improvement. Magnetic resonance in medicine. 2017 10; 78(4):1523-1532. doi: 10.1002/mrm.26519. [PMID: 27791281]
  • Khongorzul Erdene, Takahito Nakajima, Satomi Kameo, Miski Aghnia Khairinisa, Oyunbold Lamid-Ochir, Amartuvshin Tumenjargal, Noriyuki Koibuchi, Hiroshi Koyama, Yoshito Tsushima. Organ retention of gadolinium in mother and pup mice: effect of pregnancy and type of gadolinium-based contrast agents. Japanese journal of radiology. 2017 Oct; 35(10):568-573. doi: 10.1007/s11604-017-0667-2. [PMID: 28730467]
  • Alessandro Piai, Qingshan Fu, Jyoti Dev, James J Chou. Optimal Bicelle Size q for Solution NMR Studies of the Protein Transmembrane Partition. Chemistry (Weinheim an der Bergstrasse, Germany). 2017 Jan; 23(6):1361-1367. doi: 10.1002/chem.201604206. [PMID: 27747952]
  • A Adhipatria P Kartamihardja, Takahito Nakajima, Satomi Kameo, Hiroshi Koyama, Yoshito Tsushima. Distribution and clearance of retained gadolinium in the brain: differences between linear and macrocyclic gadolinium based contrast agents in a mouse model. The British journal of radiology. 2016 Oct; 89(1066):20160509. doi: 10.1259/bjr.20160509. [PMID: 27459250]
  • Kido Nwe, Ching-Hui Huang, Feini Qu, Robert Warden-Rothman, Clare Y Zhang, Robert L Mauck, Andrew Tsourkas. Cationic gadolinium chelate for magnetic resonance imaging of cartilaginous defects. Contrast media & molecular imaging. 2016 05; 11(3):229-35. doi: 10.1002/cmmi.1685. [PMID: 26853708]
  • Marvin Birka, Christoph A Wehe, Oliver Hachmöller, Michael Sperling, Uwe Karst. Tracing gadolinium-based contrast agents from surface water to drinking water by means of speciation analysis. Journal of chromatography. A. 2016 Apr; 1440(?):105-111. doi: 10.1016/j.chroma.2016.02.050. [PMID: 26931429]
  • André F Martins, Alexandre C Oliveira, Jean-François Morfin, Douglas V Laurents, Éva Tóth, Carlos F G C Geraldes. Associating a negatively charged GdDOTA-derivative to the Pittsburgh compound B for targeting Aβ amyloid aggregates. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. 2016 Mar; 21(1):83-99. doi: 10.1007/s00775-015-1316-9. [PMID: 26613605]
  • Maayke M P Kuijten, M Hannah Degeling, John W Chen, Gregory Wojtkiewicz, Peter Waterman, Ralph Weissleder, Jamil Azzi, Klaas Nicolay, Bakhos A Tannous. Multimodal targeted high relaxivity thermosensitive liposome for in vivo imaging. Scientific reports. 2015 Nov; 5(?):17220. doi: 10.1038/srep17220. [PMID: 26610702]
  • Lalit N Goswami, Quanyu Cai, Lixin Ma, Satish S Jalisatgi, M Frederick Hawthorne. Synthesis, relaxation properties and in vivo assessment of a carborane-GdDOTA-monoamide conjugate as an MRI blood pool contrast agent. Organic & biomolecular chemistry. 2015 Sep; 13(33):8912-8. doi: 10.1039/c5ob00876j. [PMID: 26204958]
  • Anthony S Malamas, Erlei Jin, Qi Zhang, John Haaga, Zheng-Rong Lu. Anti-angiogenic Effects of Bumetanide Revealed by DCE-MRI with a Biodegradable Macromolecular Contrast Agent in a Colon Cancer Model. Pharmaceutical research. 2015 Sep; 32(9):3029-43. doi: 10.1007/s11095-015-1684-4. [PMID: 25840948]
  • Nathalie Fretellier, Mariem Salhi, Josef Schroeder, Heiko Siegmund, Thibaut Chevalier, Patrick Bruneval, Gaëlle Jestin-Mayer, Francette Delaloge, Cécile Factor, Jean-François Mayer, Jean-Michel Fabicki, Caroline Robic, Bruno Bonnemain, Jean-Marc Idée, Claire Corot. Distribution profile of gadolinium in gadolinium chelate-treated renally-impaired rats: role of pharmaceutical formulation. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2015 May; 72(?):46-56. doi: 10.1016/j.ejps.2015.02.016. [PMID: 25736527]
  • Hye Rim Cho, Youkyung Lee, Philip Doble, David Bishop, Dominic Hare, Young-Jae Kim, Kwang Gi Kim, Hye Seung Jung, Kyong Soo Park, Seung Hong Choi, Woo Kyung Moon. Magnetic resonance imaging of the pancreas in streptozotocin-induced diabetic rats: Gadofluorine P and Gd-DOTA. World journal of gastroenterology. 2015 May; 21(19):5831-42. doi: 10.3748/wjg.v21.i19.5831. [PMID: 26019447]
  • Christine Egger, Catherine Cannet, Christelle Gérard, Corinne Debon, Nadine Stohler, Andrew Dunbar, Bruno Tigani, Jianping Li, Nicolau Beckmann. Adriamycin-induced nephropathy in rats: functional and cellular effects characterized by MRI. Journal of magnetic resonance imaging : JMRI. 2015 Mar; 41(3):829-40. doi: 10.1002/jmri.24603. [PMID: 24596313]
  • Ji-Ae Park, Yong Jin Lee, In Ok Ko, Tae-Jeong Kim, Yongmin Chang, Sang Moo Lim, Kyeong Min Kim, Jung Young Kim. Improved tumor-targeting MRI contrast agents: Gd(DOTA) conjugates of a cycloalkane-based RGD peptide. Biochemical and biophysical research communications. 2014 Dec; 455(3-4):246-50. doi: 10.1016/j.bbrc.2014.10.155. [PMID: 25449282]
  • Eric Gheuens, Ronald Daelemans, Sofie Mesens. Dialysability of gadoteric acid in patients with end-stage renal disease undergoing hemodialysis. Investigative radiology. 2014 Aug; 49(8):505-8. doi: 10.1097/rli.0000000000000045. [PMID: 24619209]
  • Andrea Bianchi, Sandrine Dufort, François Lux, Arnaud Courtois, Olivier Tillement, Jean-Luc Coll, Yannick Crémillieux. Quantitative biodistribution and pharmacokinetics of multimodal gadolinium-based nanoparticles for lungs using ultrashort TE MRI. Magma (New York, N.Y.). 2014 Aug; 27(4):303-16. doi: 10.1007/s10334-013-0412-5. [PMID: 24170416]
  • S H Han, F H Cho, Y K Song, J Paulsen, Y Q Song, Y R Kim, J K Kim, G Cho, H Cho. Ultrafast 3D spin-echo acquisition improves Gadolinium-enhanced MRI signal contrast enhancement. Scientific reports. 2014 May; 4(?):5061. doi: 10.1038/srep05061. [PMID: 24863102]
  • Lin Shi, Defeng Wang, Wen Liu, Kui Fang, Yi-Xiang J Wang, Wenhua Huang, Ann D King, Pheng Ann Heng, Anil T Ahuja. Automatic detection of arterial input function in dynamic contrast enhanced MRI based on affinity propagation clustering. Journal of magnetic resonance imaging : JMRI. 2014 May; 39(5):1327-37. doi: 10.1002/jmri.24259. [PMID: 24123542]
  • Joseph R Ledsam, Richard Hodgson, Robert J Moots, Steven P Sourbron. Modeling DCE-MRI at low temporal resolution: a case study on rheumatoid arthritis. Journal of magnetic resonance imaging : JMRI. 2013 Dec; 38(6):1554-63. doi: 10.1002/jmri.24061. [PMID: 23857776]
  • Clemens C Cyran, Yanjun Fu, Victor Rogut, Bundit Chaopathomkul, Michael F Wendland, David M Shames, Robert C Brasch. Evaluation of a novel macromolecular cascade-polymer contrast medium for dynamic contrast-enhanced MRI monitoring of antiangiogenic bevacizumab therapy in a human melanoma model. Academic radiology. 2013 Oct; 20(10):1256-63. doi: 10.1016/j.acra.2013.07.010. [PMID: 24029057]
  • Marvin Birka, Christoph A Wehe, Lena Telgmann, Michael Sperling, Uwe Karst. Sensitive quantification of gadolinium-based magnetic resonance imaging contrast agents in surface waters using hydrophilic interaction liquid chromatography and inductively coupled plasma sector field mass spectrometry. Journal of chromatography. A. 2013 Sep; 1308(?):125-31. doi: 10.1016/j.chroma.2013.08.017. [PMID: 23958698]
  • Erica Andreozzi, Peter Wang, Anthony Valenzuela, Chuqiao Tu, Fredric Gorin, Marc Dhenain, Angelique Louie. Size-stable solid lipid nanoparticles loaded with Gd-DOTA for magnetic resonance imaging. Bioconjugate chemistry. 2013 Sep; 24(9):1455-67. doi: 10.1021/bc300605f. [PMID: 24004269]
  • Xueming Wu, Daniel Lindner, Guan-Ping Yu, Susann Brady-Kalnay, Zheng-Rong Lu. MR molecular imaging of prostate cancer with a small molecular CLT1 peptide targeted contrast agent. Journal of visualized experiments : JoVE. 2013 Sep; ?(79):. doi: 10.3791/50565. [PMID: 24056726]
  • Gilbert Deray, Olivier Rouviere, Lorenzo Bacigalupo, Bart Maes, Thierry Hannedouche, François Vrtovsnik, Claire Rigothier, Jean-Marie Billiouw, Paolo Campioni, Joaquin Ferreiros, Daniel Devos, Daniel Alison, François Glowacki, Jean-Jacques Boffa, Luis Marti-Bonmati. Safety of meglumine gadoterate (Gd-DOTA)-enhanced MRI compared to unenhanced MRI in patients with chronic kidney disease (RESCUE study). European radiology. 2013 May; 23(5):1250-9. doi: 10.1007/s00330-012-2705-x. [PMID: 23212275]
  • Robert Ta, Mojmir Suchy, Joshua H K Tam, Alex X Li, Francisco S Martinez-Santiesteban, Timothy J Scholl, Robert H E Hudson, Robert Bartha, Stephen H Pasternak. A dual magnetic resonance imaging/fluorescent contrast agent for Cathepsin-D detection. Contrast media & molecular imaging. 2013 Mar; 8(2):127-39. doi: 10.1002/cmmi.1502. [PMID: 23281285]
  • Xueming Wu, Susan M Burden-Gulley, Guan-Ping Yu, Mingqian Tan, Daniel Lindner, Susann M Brady-Kalnay, Zheng-Rong Lu. Synthesis and evaluation of a peptide targeted small molecular Gd-DOTA monoamide conjugate for MR molecular imaging of prostate cancer. Bioconjugate chemistry. 2012 Aug; 23(8):1548-56. doi: 10.1021/bc300009t. [PMID: 22812444]
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  • Mingming Zhen, Junpeng Zheng, Lei Ye, Shumu Li, Chan Jin, Kai Li, Dong Qiu, Hongbin Han, Chunying Shu, Yongji Yang, Chunru Wang. Maximizing the relaxivity of Gd-complex by synergistic effect of HSA and carboxylfullerene. ACS applied materials & interfaces. 2012 Jul; 4(7):3724-9. doi: 10.1021/am300817z. [PMID: 22704586]
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