Morphinan-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-7-(phenylmethylene)-, (5alpha)- (BioDeep_00001028850)
代谢物信息卡片
化学式: C27H27NO4 (429.19399820000007)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1CC1CN2CCC34C5C(=O)C(=CC6=CC=CC=C6)CC3(C2CC7=C4C(=C(C=C7)O)O5)O
InChI: InChI=1S/C27H27NO4/c29-20-9-8-18-13-21-27(31)14-19(12-16-4-2-1-3-5-16)23(30)25-26(27,22(18)24(20)32-25)10-11-28(21)15-17-6-7-17/h1-5,8-9,12,17,21,25,29,31H,6-7,10-11,13-15H2/b19-12-/t21-,25+,26+,27-/m1/s1
描述信息
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D002491 - Central Nervous System Agents > D009292 - Narcotic Antagonists
同义名列表
数据库引用编号
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相关代谢途径
Reactome(0)
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PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Tsung-Chih Tseng, Duen-Yi Huang, Liang-Chuan Lai, Haw Hwai, Yi-Wen Hsiao, Jyun-Pei Jhou, Eric Y Chuang, Shiang-Jong Tzeng. Dual immuno-renal targeting of 7-benzylidenenaltrexone alleviates lupus nephritis via FcγRIIB and HO-1.
Journal of molecular medicine (Berlin, Germany).
2018 05; 96(5):413-425. doi:
10.1007/s00109-018-1626-9
. [PMID: 29508016] - Zhaoqun Liu, Zhi Zhou, Lingling Wang, Shuai Jiang, Weilin Wang, Ran Zhang, Linsheng Song. The immunomodulation mediated by a delta-opioid receptor for [Met(5)]-enkephalin in oyster Crassostrea gigas.
Developmental and comparative immunology.
2015 Apr; 49(2):217-24. doi:
10.1016/j.dci.2014.11.017
. [PMID: 25475959] - Danxin Wang, Xiaochun Sun, Wolfgang Sadee. Different effects of opioid antagonists on mu-, delta-, and kappa-opioid receptors with and without agonist pretreatment.
The Journal of pharmacology and experimental therapeutics.
2007 May; 321(2):544-52. doi:
10.1124/jpet.106.118810
. [PMID: 17267582] - Akiyoshi Saitoh, Yuji Yoshikawa, Kenji Onodera, Junzo Kamei. Role of delta-opioid receptor subtypes in anxiety-related behaviors in the elevated plus-maze in rats.
Psychopharmacology.
2005 Nov; 182(3):327-34. doi:
10.1007/s00213-005-0112-6
. [PMID: 16075288] - D Wang, K M Raehal, E J Bilsky, W Sadée. Inverse agonists and neutral antagonists at mu opioid receptor (MOR): possible role of basal receptor signaling in narcotic dependence.
Journal of neurochemistry.
2001 Jun; 77(6):1590-600. doi:
10.1046/j.1471-4159.2001.00362.x
. [PMID: 11413242] - A Coop, A E Jacobson. The LMC delta opioid recognition pharmacophore: comparison of SNC80 and oxymorphindole.
Bioorganic & medicinal chemistry letters.
1999 Feb; 9(3):357-62. doi:
10.1016/s0960-894x(98)00745-8
. [PMID: 10091684]