Ethinylestradiol-3-sulfate (BioDeep_00001028770)
代谢物信息卡片
化学式: C20H24O5S (376.1344)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC12CCC3C(C1CCC2(C#C)O)CCC4=C3C=CC(=C4)OS(=O)(=O)O
InChI: InChI=1S/C20H24O5S/c1-3-20(21)11-9-18-17-6-4-13-12-14(25-26(22,23)24)5-7-15(13)16(17)8-10-19(18,20)2/h1,5,7,12,16-18,21H,4,6,8-11H2,2H3,(H,22,23,24)/t16-,17-,18+,19+,20+/m1/s1
描述信息
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
同义名列表
1 个代谢物同义名
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Yuanxiang Jin, Xiaojian Lin, Wenyu Miao, Tao Wu, Hangjie Shen, Shan Chen, Yanhong Li, Qiaoqiao Pan, Zhengwei Fu. Chronic exposure of mice to environmental endocrine-disrupting chemicals disturbs their energy metabolism.
Toxicology letters.
2014 Mar; 225(3):392-400. doi:
10.1016/j.toxlet.2014.01.006. [PMID: 24440342] - Maciej J Zamek-Gliszczynski, Jeffrey S Day, Kathleen M Hillgren, Diane L Phillips. Efflux transport is an important determinant of ethinylestradiol glucuronide and ethinylestradiol sulfate pharmacokinetics.
Drug metabolism and disposition: the biological fate of chemicals.
2011 Oct; 39(10):1794-800. doi:
10.1124/dmd.111.040162. [PMID: 21708882] - Yong-Hae Han, Dennis Busler, Yang Hong, Yuan Tian, Cliff Chen, A David Rodrigues. Transporter studies with the 3-O-sulfate conjugate of 17alpha-ethinylestradiol: assessment of human kidney drug transporters.
Drug metabolism and disposition: the biological fate of chemicals.
2010 Jul; 38(7):1064-71. doi:
10.1124/dmd.109.031526. [PMID: 20360303] - Yong-Hae Han, Dennis Busler, Yang Hong, Yuan Tian, Cliff Chen, A David Rodrigues. Transporter studies with the 3-O-sulfate conjugate of 17alpha-ethinylestradiol: assessment of human liver drug transporters.
Drug metabolism and disposition: the biological fate of chemicals.
2010 Jul; 38(7):1072-82. doi:
10.1124/dmd.109.031518. [PMID: 20360302] - Ilaria Ceccarelli, Paolo Fiorenzani, Daniele Della Seta, Cosimo Massafra, Giuliano Cinci, Anna Bocci, Anna Maria Aloisi. Perinatal exposure to xenoestrogens affects pain in adult female rats.
Neurotoxicology and teratology.
2009 Jul; 31(4):203-9. doi:
10.1016/j.ntt.2009.02.004. [PMID: 19264124] - R Scott Obach, Franco Lombardo, Nigel J Waters. Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Drug metabolism and disposition: the biological fate of chemicals.
2008 Jul; 36(7):1385-405. doi:
10.1124/dmd.108.020479. [PMID: 18426954] - S G Lundeen, J M Carver, M L McKean, R C Winneker. Characterization of the ovariectomized rat model for the evaluation of estrogen effects on plasma cholesterol levels.
Endocrinology.
1997 Apr; 138(4):1552-8. doi:
10.1210/endo.138.4.5083. [PMID: 9075715] - J W Goldzieher, G Mileikowsky, J Newburger, A Dorantes, S A Stavchansky. Human pharmacokinetics of ethynyl estradiol 3-sulfate and 17-sulfate.
Steroids.
1988 Jan; 51(1-2):63-79. doi:
10.1016/0039-128x(88)90185-7. [PMID: 3242167] - J Newburger, V D Castracane, P H Moore, M C Williams, J W Goldzieher. The pharmacokinetics and metabolism of ethinyl estradiol and its three sulfates in the baboon.
American journal of obstetrics and gynecology.
1983 May; 146(1):80-7. doi:
10.1016/0002-9378(83)90931-6. [PMID: 6846427] - M J Reed, K Fotherby. Interaction of ethynyloestradiol sulphate with plasma proteins.
Journal of steroid biochemistry.
1980 May; 13(5):495-7. doi:
10.1016/0022-4731(80)90204-6. [PMID: 7392627]
