Tripamide (BioDeep_00001028741)
代谢物信息卡片
化学式: C16H20ClN3O3S (369.09138400000006)
中文名称: 卓波酰胺
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1CC2CC1C3C2CN(C3)NC(=O)C4=CC(=C(C=C4)Cl)S(=O)(=O)N
InChI: InChI=1S/C16H20ClN3O3S/c17-14-4-3-11(6-15(14)24(18,22)23)16(21)19-20-7-12-9-1-2-10(5-9)13(12)8-20/h3-4,6,9-10,12-13H,1-2,5,7-8H2,(H,19,21)(H2,18,22,23)/t9-,10+,12-,13+
描述信息
D045283 - Natriuretic Agents > D004232 - Diuretics > D049994 - Sodium Potassium Chloride Symporter Inhibitors
D002317 - Cardiovascular Agents > D045283 - Natriuretic Agents
C78275 - Agent Affecting Blood or Body Fluid > C448 - Diuretic
D049990 - Membrane Transport Modulators
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yunje Kim, Joungboon Hwang, Myungsoo Kim, Won Lee. Determination of Tripamide in human urine by high-performance liquid chromatography and high-performance liquid chromatography/electrospray ionization tandem mass spectrometry.
Rapid communications in mass spectrometry : RCM.
2003; 17(4):301-6. doi:
10.1002/rcm.913. [PMID: 12569439] - K A Conrad, T C Fagan, J A Simons. The influence of hydrochlorothiazide and tripamide on serum and urinary amylase.
Journal of clinical pharmacology.
1988 May; 28(5):436-40. doi:
10.1002/j.1552-4604.1988.tb05756.x. [PMID: 2455741] - E T Bope, R C Adams, S C Brewer, C B Cairns, N R Fosnaugh, P C Leidheiser, C W Platt, J S Polsley, R R Romaker, S D Scarbrough. Multicenter private practice comparison of tripamide and hydrochlorothiazide in the treatment of hypertension.
Family practice research journal.
1988; 7(4):197-204. doi:
NULL. [PMID: 3075410] - K A Conrad, T C Fagan, S M Lee, J A Simons. Effect of tripamide on glucose tolerance in patients with hypertension.
Clinical pharmacology and therapeutics.
1986 Oct; 40(4):476-9. doi:
10.1038/clpt.1986.209. [PMID: 3530589] - T C Fagan, K A Conrad, S Lee, J H Mar, J Simons. Antihypertensive and biochemical dose-response study of tripamide.
Clinical pharmacology and therapeutics.
1986 Sep; 40(3):352-8. doi:
10.1038/clpt.1986.187. [PMID: 3527514] - D C Brater, S Anderson. Sites of action of tripamide.
Clinical pharmacology and therapeutics.
1983 Jul; 34(1):79-85. doi:
10.1038/clpt.1983.133. [PMID: 6861441] - T Horie, T Ohno, K Kinoshita. Studies on metabolism of tripamide. III. Metabolic fate of 14C-tripamide in rats and rabbits.
Japanese journal of pharmacology.
1982 Dec; 32(6):1041-9. doi:
10.1254/jjp.32.1041. [PMID: 7161960] - T Horie, T Ohno, K Kinoshita. Determination of tripamide and its metabolites in plasma, red blood cells and urine by high-performance liquid chromatography.
Journal of chromatography.
1982 Aug; 231(1):111-9. doi:
10.1016/s0378-4347(00)80514-9. [PMID: 7119053] - T Horie, T Ohno, K Kinoshita. Studies on the metabolism of tripamide, a new antihypertensive agent. I. Characterization of metabolites in rats.
Xenobiotica; the fate of foreign compounds in biological systems.
1981 Mar; 11(3):197-206. doi:
10.3109/00498258109045292. [PMID: 7293216]