Sekisanolin (BioDeep_00001028727)

   


代谢物信息卡片


8H-[1,3]Dioxolo[6,7][2]benzopyrano[3,4-c]indol-6a(3H)-ol,4,4a,5,6-tetrahydro-3-methoxy-5-methyl-, (3S,4aS,6aS,13bS)-

  化学式: C18H21NO5 (331.142)
中文名称: 多花水仙碱
  谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CN1CC2(C3(C1CC(C=C3)OC)C4=CC5=C(C=C4CO2)OCO5)O
InChI: InChI=1S/C18H21NO5/c1-19-9-18(20)17(4-3-12(21-2)6-16(17)19)13-7-15-14(22-10-23-15)5-11(13)8-24-18/h3-5,7,12,16,20H,6,8-10H2,1-2H3/t12-,16+,17+,18-/m1/s1


描述信息

同义名列表

3 个代谢物同义名

8H-[1,3]Dioxolo[6,7][2]benzopyrano[3,4-c]indol-6a(3H)-ol,4,4a,5,6-tetrahydro-3-methoxy-5-methyl-, (3S,4aS,6aS,13bS)-; Sekisanolin; Tazettine



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Daniel Zaragoza-Puchol, Javier E Ortiz, Alejandro A Orden, Marianela Sanchez, Jorge Palermo, Alejandro Tapia, Jaume Bastida, Gabriela E Feresin. Alkaloids Analysis of Habranthus cardenasianus (Amaryllidaceae), Anti-Cholinesterase Activity and Biomass Production by Propagation Strategies. Molecules (Basel, Switzerland). 2021 Jan; 26(1):. doi: 10.3390/molecules26010192. [PMID: 33401696]
  • Jerald J Nair, Johannes van Staden. Antiprotozoal alkaloid principles of the plant family Amaryllidaceae. Bioorganic & medicinal chemistry letters. 2019 10; 29(20):126642. doi: 10.1016/j.bmcl.2019.126642. [PMID: 31515186]
  • Ameneh Tarakemeh, Majid Azizi, Vahid Rowshan, Hassan Salehi, Rosella Spina, François Dupire, Hossein Arouie, Dominique Laurain-Mattar. Screening of Amaryllidaceae alkaloids in bulbs and tissue cultures of Narcissus papyraceus and four varieties of N. tazetta. Journal of pharmaceutical and biomedical analysis. 2019 Aug; 172(?):230-237. doi: 10.1016/j.jpba.2019.04.043. [PMID: 31060036]
  • Shuangjiao Sun, Yanfen Wei, Yupin Cao, Biyang Deng. Simultaneous electrochemiluminescence determination of galanthamine, homolycorine, lycorenine, and tazettine in Lycoris radiata by capillary electrophoresis with ultrasonic-assisted extraction. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2017 Jun; 1055-1056(?):15-19. doi: 10.1016/j.jchromb.2017.04.020. [PMID: 28441543]
  • Marco Masi, Alet E van der Westhuyzen, Nurhayat Tabanca, Marco Evidente, Alessio Cimmino, Ivan R Green, Ulrich R Bernier, James J Becnel, Jeffrey R Bloomquist, Willem A L van Otterlo, Antonio Evidente. Sarniensine, a mesembrine-type alkaloid isolated from Nerine sarniensis, an indigenous South African Amaryllidaceae, with larvicidal and adulticidal activities against Aedes aegypti. Fitoterapia. 2017 Jan; 116(?):34-38. doi: 10.1016/j.fitote.2016.11.007. [PMID: 27864138]
  • Jean Paulo de Andrade, Natalia Belén Pigni, Laura Torras-Claveria, Strahil Berkov, Carles Codina, Francesc Viladomat, Jaume Bastida. Bioactive alkaloid extracts from Narcissus broussonetii: mass spectral studies. Journal of pharmaceutical and biomedical analysis. 2012 Nov; 70(?):13-25. doi: 10.1016/j.jpba.2012.05.009. [PMID: 22673940]
  • M Jokhadze, J Kuchukhidze, D Chincharadze, T Murtazashvili. Biological active compounds from Georgian Galanthus shaoricus. Georgian medical news. 2011 Oct; ?(199):91-4. doi: . [PMID: 22155813]
  • Raquel B Giordani, Jean P de Andrade, Hugo Verli, Julie H Dutilh, Amélia T Henriques, Strahil Berkov, Jaume Bastida, José Angelo S Zuanazzi. Alkaloids from Hippeastrum morelianum Lem. (Amaryllidaceae). Magnetic resonance in chemistry : MRC. 2011 Oct; 49(10):668-72. doi: 10.1002/mrc.2794. [PMID: 21898585]
  • Strahil Berkov, Atanas Pavlov, Vasil Georgiev, Jost Weber, Thomas Bley, Francesc Viladomat, Jaume Bastida, Carles Codina. Changes in apolar metabolites during in vitro organogenesis of Pancratium maritimum. Plant physiology and biochemistry : PPB. 2010 Oct; 48(10-11):827-35. doi: 10.1016/j.plaphy.2010.07.002. [PMID: 20702100]
  • Filomena Conforti, Monica Rosa Loizzo, Mariangela Marrelli, Federica Menichini, Giancarlo A Statti, Dimitar Uzunov, Francesco Menichini. Quantitative determination of Amaryllidaceae alkaloids from Galanthus reginae-olgae subsp. vernalis and in vitro activities relevant for neurodegenerative diseases. Pharmaceutical biology. 2010 Jan; 48(1):2-9. doi: 10.3109/13880200903029308. [PMID: 20645749]
  • M H Salehi Sourmaghi, B Azadi, Gh Amin, M Amini, M Sharifzadeh. The first phytochemical report of Galanthus transcaucasicus Fomin. Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences. 2010; 18(2):124-7. doi: . [PMID: 22615606]
  • Strahil Berkov, Jaume Bastida, Reneta Tsvetkova, Francesc Viladomat, Carles Codina. Alkaloids from Sternbergia colchiciflora. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2009 May; 64(5-6):311-6. doi: 10.1515/znc-2009-5-601. [PMID: 19678530]
  • Kirandeep Kaur, Meenakshi Jain, Tarandeep Kaur, Rahul Jain. Antimalarials from nature. Bioorganic & medicinal chemistry. 2009 May; 17(9):3229-56. doi: 10.1016/j.bmc.2009.02.050. [PMID: 19299148]
  • Antonio Evidente, Artem S Kireev, Aaron R Jenkins, Anntherese E Romero, Wim F A Steelant, Severine Van Slambrouck, Alexander Kornienko. Biological evaluation of structurally diverse amaryllidaceae alkaloids and their synthetic derivatives: discovery of novel leads for anticancer drug design. Planta medica. 2009 Apr; 75(5):501-7. doi: 10.1055/s-0029-1185340. [PMID: 19235683]
  • Esameldin E Elgorashi, Gary I Stafford, Anna K Jäger, Johannes van Staden. Inhibition of [3H]citalopram binding to the rat brain serotonin transporter by Amaryllidaceae alkaloids. Planta medica. 2006 Apr; 72(5):470-3. doi: 10.1055/s-2005-916251. [PMID: 16557463]
  • Bilge Sener, Ilkay Orhan, Jutamad Satayavivad. Antimalarial activity screening of some alkaloids and the plant extracts from Amaryllidaceae. Phytotherapy research : PTR. 2003 Dec; 17(10):1220-3. doi: 10.1002/ptr.1346. [PMID: 14669261]
  • Susana López, Jaume Bastida, Francesc Viladomat, Carles Codina. Solid-phase extraction and reversed-phase high-performance liquid chromatography of the five major alkaloids in Narcissus confusus. Phytochemical analysis : PCA. 2002 Nov; 13(6):311-5. doi: 10.1002/pca.660. [PMID: 12494748]
  • Judit Hohmann, Peter Forgo, Joseph Molnár, Krisztina Wolfard, Annamária Molnár, Theresia Thalhammer, Imre Máthé, Derek Sharples. Antiproliferative amaryllidaceae alkaloids isolated from the bulbs of Sprekelia formosissima and Hymenocallis x festalis. Planta medica. 2002 May; 68(5):454-7. doi: 10.1055/s-2002-32068. [PMID: 12058326]
  • S W Baldwin, J S Debenham. Total syntheses of (-)-haemanthidine, (+)-pretazettine, and (+)-tazettine. Organic letters. 2000 Jan; 2(2):99-102. doi: 10.1021/ol9911472. [PMID: 10814256]
  • M O James, J R Fouts, J R Bend. Hepatic and extrahepatic metabolism, in vitro, of an epoxide (8-(14) C-styrene oxide) in the rabbit. Biochemical pharmacology. 1976 Jan; 25(2):187-93. doi: 10.1016/0006-2952(76)90289-6. [PMID: 4076]
  • J Harkness. Why urinalysis?. The Central African journal of medicine. 1975 Aug; 21(8):178-83. doi: NULL. [PMID: 1150]