7-Keto-dehydroepiandrosterone (BioDeep_00001028718)
代谢物信息卡片
化学式: C19H26O3 (302.1881846)
中文名称: 7-酮基去氢表雄酮
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC12CCC3C(C1CCC2=O)C(=O)C=C4C3(CCC(C4)O)C
InChI: InChI=1S/C19H26O3/c1-18-7-5-12(20)9-11(18)10-15(21)17-13-3-4-16(22)19(13,2)8-6-14(17)18/h10,12-14,17,20H,3-9H2,1-2H3/t12-,13-,14-,17-,18-,19-/m0/s1
描述信息
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Dayamín Martínez Brito, Patrizia Leogrande, Cristiana Colamonici, Davide Curcio, Francesco Botre, Xavier de la Torre. Arimistane: Degradation product or metabolite of 7-oxo-DHEA?.
Drug testing and analysis.
2021 Jul; 13(7):1430-1439. doi:
10.1002/dta.3036. [PMID: 33783974] - Dayamin Martinez-Brito, Xavier de la Torre, Cristiana Colamonici, Davide Curcio, Francesco Botrè. 7-keto-DHEAmetabolism in humans. Pitfalls in interpreting the analytical results in the antidoping field.
Drug testing and analysis.
2019 Nov; 11(11-12):1629-1643. doi:
10.1002/dta.2734. [PMID: 31701664] - Anna Panek, Alina Świzdor, Natalia Milecka-Tronina, Jarosław J Panek. Insight into the orientational versatility of steroid substrates-a docking and molecular dynamics study of a steroid receptor and steroid monooxygenase.
Journal of molecular modeling.
2017 Mar; 23(3):96. doi:
10.1007/s00894-017-3278-z. [PMID: 28251412] - Lucie Kolatorova Sosvorova, Jan Sarek, Jana Vitku, Miroslav Kvasnica. Synthesis of 3α-deuterated 7α-hydroxy-DHEA and 7-oxo-DHEA and application in LC-MS/MS plasma analysis.
Steroids.
2016 08; 112(?):88-94. doi:
10.1016/j.steroids.2016.05.001. [PMID: 27192427] - Tânia R Dias, Marco G Alves, Susana P Almeida, Joaquina Silva, Alberto Barros, Mário Sousa, Branca M Silva, Samuel M Silvestre, Pedro F Oliveira. Dehydroepiandrosterone and 7-oxo-dehydroepiandrosterone in male reproductive health: Implications of differential regulation of human Sertoli cells metabolic profile.
The Journal of steroid biochemistry and molecular biology.
2015 Nov; 154(?):1-11. doi:
10.1016/j.jsbmb.2015.06.004. [PMID: 26134425] - H Kazihnitková, L Zamrazilová, M Hill, O Lapcík, V Pouzar, R Hampl. A novel radioimmunoassay of 7-oxo-DHEA and its physiological levels.
Steroids.
2007 Apr; 72(4):342-50. doi:
10.1016/j.steroids.2006.12.005. [PMID: 17298836] - Boaz Robinzon, Kristy K Michael, Sharon L Ripp, Stephen J Winters, Russell A Prough. Glucocorticoids inhibit interconversion of 7-hydroxy and 7-oxo metabolites of dehydroepiandrosterone: a role for 11beta-hydroxysteroid dehydrogenases?.
Archives of biochemistry and biophysics.
2003 Apr; 412(2):251-8. doi:
10.1016/s0003-9861(03)00056-0. [PMID: 12667489] - A Marwah, P Marwah, H Lardy. Development and validation of a high-performance liquid chromatography assay for the quantitative determination of 7-oxo-dehydroepiandrosterone-3beta-sulfate in human plasma.
Journal of chromatography. B, Biomedical sciences and applications.
1999 Jan; 721(2):197-205. doi:
10.1016/s0378-4347(98)00474-5. [PMID: 10052692] - M K Samson, R L Stephens, S Rivkin, M Opipari, T Maloney, C W Groppe, R Fisher. Vinblastine, bleomycin, and cis-dichlorodiammineplatinum(II) in disseminated testicular cancer: preliminary report of a Southwest Oncology Group Study.
Cancer treatment reports.
1979 Sep; 63(9-10):1663-7. doi:
. [PMID: 91435]