Argiprestocin (BioDeep_00001028707)

   


代谢物信息卡片


(Arg8)-Vasotocin acetate salt

化学式: C43H67N15O12S2 (1049.4535)
中文名称: [Arg8]-催产加压素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)N1)CC2=CC=C(C=C2)O)N)C(=O)N3CCCC3C(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)N)CC(=O)N)CCC(=O)N
InChI: InChI=1S/C43H67N15O12S2/c1-3-21(2)34-41(69)53-26(12-13-31(45)60)37(65)55-28(17-32(46)61)38(66)56-29(20-72-71-19-24(44)35(63)54-27(39(67)57-34)16-22-8-10-23(59)11-9-22)42(70)58-15-5-7-30(58)40(68)52-25(6-4-14-50-43(48)49)36(64)51-18-33(47)62/h8-11,21,24-30,34,59H,3-7,12-20,44H2,1-2H3,(H2,45,60)(H2,46,61)(H2,47,62)(H,51,64)(H,52,68)(H,53,69)(H,54,63)(H,55,65)(H,56,66)(H,57,67)(H4,48,49,50)/t21-,24-,25-,26-,27-,28-,29-,30-,34-/m0/s1

描述信息

D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
D002317 - Cardiovascular Agents > D014662 - Vasoconstrictor Agents
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone
D012102 - Reproductive Control Agents > D010120 - Oxytocics

同义名列表

2 个代谢物同义名

(Arg8)-Vasotocin acetate salt; Argiprestocin



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • A Rawat, R Chaube, K P Joy. Air sac and gill vasotocin receptor gene expression in the air-breathing catfish Heteropneustes fossilis exposed to water and air deprivation conditions. Fish physiology and biochemistry. 2022 Apr; 48(2):381-395. doi: 10.1007/s10695-022-01058-4. [PMID: 35166960]
  • Tobias Backström, Per-Ove Thörnqvist, Svante Winberg. Social effects on AVT and CRF systems. Fish physiology and biochemistry. 2021 Dec; 47(6):1699-1709. doi: 10.1007/s10695-021-00995-w. [PMID: 34476683]
  • Ivaldo Jesus Almeida Belém-Filho, Taíz Francine Silva Brasil, Eduardo Albino Trindade Fortaleza, José Antunes-Rodrigues, Fernando Morgan Aguiar Corrêa. A functional selective effect of oxytocin secreted under restraint stress in rats. European journal of pharmacology. 2021 Aug; 904(?):174182. doi: 10.1016/j.ejphar.2021.174182. [PMID: 34004212]
  • Hakeem J Kadhim, Michael Kidd, Seong W Kang, Wayne J Kuenzel. Differential delayed responses of arginine vasotocin and its receptors in septo-hypothalamic brain structures and anterior pituitary that sustain hypothalamic-pituitary-adrenal (HPA) axis functions during acute stress. General and comparative endocrinology. 2020 01; 286(?):113302. doi: 10.1016/j.ygcen.2019.113302. [PMID: 31622604]
  • Susan E Orosz, M Scott Echols. The Urinary and Osmoregulatory Systems of Birds. The veterinary clinics of North America. Exotic animal practice. 2020 Jan; 23(1):1-19. doi: 10.1016/j.cvex.2019.09.001. [PMID: 31759441]
  • S Santos, C Haslinger, M Mennet, U von Mandach, M Hamburger, A P Simões-Wüst. Bryophyllum pinnatum enhances the inhibitory effect of atosiban and nifedipine on human myometrial contractility: an in vitro study. BMC complementary and alternative medicine. 2019 Nov; 19(1):292. doi: 10.1186/s12906-019-2711-5. [PMID: 31685022]
  • Takashi Haramura, Taro Ikegami, Marty K S Wong, Yoshio Takei. Preparatory Mechanisms for Salinity Tolerance in Two Congeneric Anuran Species Inhabiting Distinct Osmotic Habitats. Zoological science. 2019 06; 36(3):215-222. doi: 10.2108/zs180091. [PMID: 31251490]
  • L Herve, V Lollivier, H Quesnel, Marion Boutinaud. Oxytocin Induces Mammary Epithelium Disruption and Could Stimulate Epithelial Cell Exfoliation. Journal of mammary gland biology and neoplasia. 2018 09; 23(3):139-147. doi: 10.1007/s10911-018-9400-8. [PMID: 29948751]
  • Peter Keov, Zita Liutkevičiūtė, Roland Hellinger, Richard J Clark, Christian W Gruber. Discovery of peptide probes to modulate oxytocin-type receptors of insects. Scientific reports. 2018 07; 8(1):10020. doi: 10.1038/s41598-018-28380-3. [PMID: 29968789]
  • Juan Miguel Mancera, Gonzalo Martínez-Rodríguez, Arleta Krystyna Skrzynska, Juan Antonio Martos-Sitcha. Osmoregulatory role of vasotocinergic and isotocinergic systems in the gilthead sea bream (Sparus aurata L). General and comparative endocrinology. 2018 02; 257(?):177-183. doi: 10.1016/j.ygcen.2017.01.005. [PMID: 28065737]
  • Ali Mohammad Alizadeh, Zahra Heydari, Mostafa Rahimi, Behzad Bazgir, Hossein Shirvani, Sadaf Alipour, Yassaman Heidarian, Solmaz Khalighfard, Amin Isanejad. Oxytocin mediates the beneficial effects of the exercise training on breast cancer. Experimental physiology. 2018 02; 103(2):222-235. doi: 10.1113/ep086463. [PMID: 29143998]
  • Mariusz Grzesiak, Zuzanna Gaj, Rafał Kocyłowski, Joanna Suliburska, Przemysław Oszukowski, Wojciech Horzelski, Constantin von Kaisenberg, Maciej Banach. Oxidative Stress in Women Treated with Atosiban for Impending Preterm Birth. Oxidative medicine and cellular longevity. 2018; 2018(?):3919106. doi: 10.1155/2018/3919106. [PMID: 30622667]
  • Arleta Krystyna Skrzynska, Juan Antonio Martos-Sitcha, Gonzalo Martínez-Rodríguez, Juan Miguel Mancera. Unraveling vasotocinergic, isotocinergic and stress pathways after food deprivation and high stocking density in the gilthead sea bream. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 2018 01; 215(?):35-44. doi: 10.1016/j.cbpa.2017.10.012. [PMID: 29079226]
  • Mohammad Yousef, Elara N Moudilou, Hafsa Djoudad-Kadji, Jean-Marie Exbrayat. Study of the hydromineral regulation of Typhlonectes compressicauda according to the seasonal variation. Folia histochemica et cytobiologica. 2018; 56(3):172-183. doi: 10.5603/fhc.a2018.0016. [PMID: 30070682]
  • Umit M Kocyigit, Ahmet Şevki Taşkıran, Parham Taslimi, Ahmet Yokuş, Yusuf Temel, İlhami Gulçin. Inhibitory effects of oxytocin and oxytocin receptor antagonist atosiban on the activities of carbonic anhydrase and acetylcholinesterase enzymes in the liver and kidney tissues of rats. Journal of biochemical and molecular toxicology. 2017 Nov; 31(11):. doi: 10.1002/jbt.21972. [PMID: 29116677]
  • Arleta Krystyna Skrzynska, Magdalena Gozdowska, Ewa Kulczykowska, Gonzalo Martínez-Rodríguez, Juan Miguel Mancera, Juan Antonio Martos-Sitcha. The effect of starvation and re-feeding on vasotocinergic and isotocinergic pathways in immature gilthead sea bream (Sparus aurata). Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology. 2017 Oct; 187(7):945-958. doi: 10.1007/s00360-017-1064-y. [PMID: 28251326]
  • A V Sirotkin, A H Harrath, R Grossmann. Metabolic status and ghrelin regulate plasma levels and release of ovarian hormones in layer chicks. Physiological research. 2017 03; 66(1):85-92. doi: 10.33549/physiolres.933306. [PMID: 27782746]
  • Gurueswar Nagarajan, Seong W Kang, Wayne J Kuenzel. Functional evidence that the nucleus of the hippocampal commissure shows an earlier activation from a stressor than the paraventricular nucleus: Implication of an additional structural component of the avian hypothalamo-pituitary-adrenal axis. Neuroscience letters. 2017 03; 642(?):14-19. doi: 10.1016/j.neulet.2017.01.064. [PMID: 28137650]
  • Rashmi Srivastava, Chandra Mohini Chaturvedi. Expression of arginine vasotocin and estrogen receptor alpha (ERα) in the shell gland altered by the specific phase relations of neural oscillations affects the reproductive physiology of Japanese quail. Physiology & behavior. 2016 10; 165(?):98-107. doi: 10.1016/j.physbeh.2016.07.001. [PMID: 27394660]
  • A V Kutina, D V Golosova, A S Marina, T A Karavashkina, Yu V Natochin. [EFFECTS OF ORALLY AND PARENTERALLY ADMINISTERED ANALOGS OF PEPTIDE HORMONES ON RENAL WATER AND ION TRANSPORT]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. 2016 Oct; 102(10):1185-94. doi: NULL. [PMID: 30193436]
  • Ye He, Huan Wu, Xiaojin He, Qiong Xing, Ping Zhou, Yunxia Cao, Zhaolian Wei. Administration of atosiban in patients with endometriosis undergoing frozen-thawed embryo transfer: a prospective, randomized study. Fertility and sterility. 2016 Aug; 106(2):416-22. doi: 10.1016/j.fertnstert.2016.04.019. [PMID: 27143518]
  • Rafael Taeho Han, Hyunkyoung Lee, JaeHee Lee, Sat-Byol Lee, Hee Jin Kim, Seung Keun Back, Heung Sik Na. Brief Isolation Changes Nociceptive Behaviors and Compromises Drug Tests in Mice. Pain practice : the official journal of World Institute of Pain. 2016 07; 16(6):749-57. doi: 10.1111/papr.12325. [PMID: 26212903]
  • Richard J Kline, G Joan Holt, Izhar A Khan. Arginine vasotocin V1a2 receptor and GnRH-I co-localize in preoptic neurons of the sex changing grouper, Epinephelus adscensionis. General and comparative endocrinology. 2016 Jan; 225(?):33-44. doi: 10.1016/j.ygcen.2015.07.013. [PMID: 26361870]
  • Radha Chaube, Rahul Kumar Singh, Keerikattil P Joy. Changes in vasotocin levels in relation to ovarian development in the catfish Heteropneustes fossilis exposed to altered photoperiod and temperature. Fish physiology and biochemistry. 2015 Oct; 41(5):1173-86. doi: 10.1007/s10695-015-0078-1. [PMID: 26026296]
  • Masakazu Suzuki, Yuki Shibata, Yuji Ogushi, Reiko Okada. Molecular machinery for vasotocin-dependent transepithelial water movement in amphibians: aquaporins and evolution. The Biological bulletin. 2015 Aug; 229(1):109-19. doi: 10.1086/bblv229n1p109. [PMID: 26338873]
  • D V Golosova, A V Kutina, A S Marina, T A Karavashkina, Yu V Natochin. [PHYSIOLOGICAL APPROACH TO RESTORING OSMOTIC HOMEOSTASIS IN RATS WITH HYPERNATREMIA]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. 2015 Jul; 101(7):804-11. doi: NULL. [PMID: 26591053]
  • J H Jiang, Z He, Y L Peng, W D Jin, J Mu, H X Xue, Z Wang, M Chang, R Wang. Effects of Phoenixin-14 on anxiolytic-like behavior in mice. Behavioural brain research. 2015 Jun; 286(?):39-48. doi: 10.1016/j.bbr.2015.02.011. [PMID: 25687846]
  • S Babic, M Pokusa, V Danevova, S T Ding, D Jezova. Effects of atosiban on stress-related neuroendocrine factors. The Journal of endocrinology. 2015 Apr; 225(1):9-17. doi: 10.1530/joe-14-0560. [PMID: 25609735]
  • Lin S Huffman, Flora I Hinz, Sophie Wojcik, Nadia Aubin-Horth, Hans A Hofmann. Arginine vasotocin regulates social ascent in the African cichlid fish Astatotilapia burtoni. General and comparative endocrinology. 2015 Feb; 212(?):106-13. doi: 10.1016/j.ygcen.2014.03.004. [PMID: 24662391]
  • Laura Cádiz, Javier Román-Padilla, Magdalena Gozdowska, Ewa Kulczykowska, Gonzalo Martínez-Rodríguez, Juan M Mancera, Juan A Martos-Sitcha. Cortisol modulates vasotocinergic and isotocinergic pathways in the gilthead sea bream. The Journal of experimental biology. 2015 Jan; 218(Pt 2):316-25. doi: 10.1242/jeb.113944. [PMID: 25524977]
  • Fariba Houshmand, Mahdieh Faghihi, Saleh Zahediasl. Role of atrial natriuretic Peptide in oxytocin induced cardioprotection. Heart, lung & circulation. 2015 Jan; 24(1):86-93. doi: 10.1016/j.hlc.2014.05.023. [PMID: 25126708]
  • Ernest Hung Yu Ng, Raymond Hang Wun Li, Leining Chen, Vuong Thi Ngoc Lan, Ho Manh Tuong, Song Quan. A randomized double blind comparison of atosiban in patients undergoing IVF treatment. Human reproduction (Oxford, England). 2014 Dec; 29(12):2687-94. doi: 10.1093/humrep/deu263. [PMID: 25336707]
  • A V Kutina, T A Karavashkina, D V Holasava, Yu V Natochin. [Effects of neurohypophysial nonapeptides and their analogues on magnesium excretion by rat kidney]. Zhurnal evoliutsionnoi biokhimii i fiziologii. 2014 Nov; 50(6):435-9. doi: NULL. [PMID: 25782284]
  • Alexander V Sirotkin, Peter Chrenek, Adriana Kolesarová, Francesco Parillo, Massimo Zerani, Cristiano Boiti. Novel regulators of rabbit reproductive functions. Animal reproduction science. 2014 Aug; 148(3-4):188-96. doi: 10.1016/j.anireprosci.2014.06.001. [PMID: 24957967]
  • Nao Kagawa. Comparison of aggressive behaviors between two wild populations of Japanese medaka, Oryzias latipes and O. sakaizumii. Zoological science. 2014 Mar; 31(3):116-21. doi: 10.2108/zsj.31.116. [PMID: 24601772]
  • Abdelkareem A Ahmed, Wenqiang Ma, Yingdong Ni, Qin Zhou, Ruqian Zhao. Embryonic exposure to corticosterone modifies aggressive behavior through alterations of the hypothalamic pituitary adrenal axis and the serotonergic system in the chicken. Hormones and behavior. 2014 Feb; 65(2):97-105. doi: 10.1016/j.yhbeh.2013.12.002. [PMID: 24333411]
  • M Gesto, J L Soengas, A Rodríguez-Illamola, J M Míguez. Arginine vasotocin treatment induces a stress response and exerts a potent anorexigenic effect in rainbow trout, Oncorhynchus mykiss. Journal of neuroendocrinology. 2014 Feb; 26(2):89-99. doi: 10.1111/jne.12126. [PMID: 24341528]
  • J A Martos-Sitcha, J Fuentes, J M Mancera, G Martínez-Rodríguez. Variations in the expression of vasotocin and isotocin receptor genes in the gilthead sea bream Sparus aurata during different osmotic challenges. General and comparative endocrinology. 2014 Feb; 197(?):5-17. doi: 10.1016/j.ygcen.2013.11.026. [PMID: 24332959]
  • Brent W Roberts, Wes Didier, Satbir Rai, Nicholas S Johnson, Scot Libants, Sang-Seon Yun, David A Close. Regulation of a putative corticosteroid, 17,21-dihydroxypregn-4-ene,3,20-one, in sea lamprey, Petromyzon marinus. General and comparative endocrinology. 2014 Jan; 196(?):17-25. doi: 10.1016/j.ygcen.2013.11.008. [PMID: 24287339]
  • R Chaube, R K Singh, K P Joy. Effects of ovaprim, a commercial spawning inducer, on vasotocin and steroid hormone profiles in the catfish Heteropneustes fossilis: in vivo and in vitro studies. General and comparative endocrinology. 2014 Jan; 195(?):190-200. doi: 10.1016/j.ygcen.2013.11.009. [PMID: 24246310]
  • Minoru Uchiyama, Sho Maejima, Marty K S Wong, Narin Preyavichyapugdee, Chaitip Wanichanon, Susumu Hyodo, Yoshio Takei, Kouhei Matuda. Changes in plasma angiotensin II, aldosterone, arginine vasotocin, corticosterone, and electrolyte concentrations during acclimation to dry condition and seawater in the crab-eating frog. General and comparative endocrinology. 2014 Jan; 195(?):40-6. doi: 10.1016/j.ygcen.2013.10.013. [PMID: 24184110]
  • Naguib Salleh, Vivi Noryati Ahmad. In-VITRo effect of Ficus deltoidea on the contraction of isolated rat's uteri is mediated via multiple receptors binding and is dependent on extracellular calcium. BMC complementary and alternative medicine. 2013 Dec; 13(?):359. doi: 10.1186/1472-6882-13-359. [PMID: 24330515]
  • Rahul Kumar Singh, Radha Chaube, Keerikkattil P Joy. Differential and reproductive stage-dependent regulation of vasotocin secretion by catecholamines in the catfish Heteropneustes fossilis. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 2013 Dec; 166(4):619-26. doi: 10.1016/j.cbpa.2013.09.005. [PMID: 24036478]
  • J A Martos-Sitcha, Y S Wunderink, M Gozdowska, E Kulczykowska, J M Mancera, G Martínez-Rodríguez. Vasotocinergic and isotocinergic systems in the gilthead sea bream (Sparus aurata): an osmoregulatory story. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 2013 Dec; 166(4):571-81. doi: 10.1016/j.cbpa.2013.09.001. [PMID: 24021911]
  • Nao Kagawa, Yudai Nishiyama, Kanoko Kato, Hideya Takahashi, Yasuhisa Kobayashi, Hirotaka Sakamoto, Tatsuya Sakamoto. Potential roles of arginine-vasotocin in the regulation of aggressive behavior in the mudskipper (Periophthalmus modestus). General and comparative endocrinology. 2013 Dec; 194(?):257-63. doi: 10.1016/j.ygcen.2013.09.023. [PMID: 24113694]
  • Juan Antonio Martos-Sitcha, Silvia Filipa Gregório, Edison Samir M Carvalho, Adelino Vicente M Canario, Deborah Mary Power, Juan Miguel Mancera, Gonzalo Martínez-Rodríguez, Juan Fuentes. AVT is involved in the regulation of ion transport in the intestine of the sea bream (Sparus aurata). General and comparative endocrinology. 2013 Nov; 193(?):221-8. doi: 10.1016/j.ygcen.2013.07.017. [PMID: 23973797]
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  • Ewa Sokołowska, Agnieszka Kleszczyńska, Hanna Kalamarz-Kubiak, Bartłomiej Arciszewski, Ewa Kulczykowska. Changes in brain arginine vasotocin, isotocin, plasma 11-ketotestosterone and cortisol in round goby, Neogobius melanostomus, males subjected to overcrowding stress during the breeding season. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 2013 Jun; 165(2):237-42. doi: 10.1016/j.cbpa.2013.03.018. [PMID: 23524055]
  • Anna V Kutina, Anna S Marina, Ivan I Eliseev, Mikhail I Titov, Yuri V Natochin. Synthesis of new vasotocin analogues: effects on renal water and ion excretion in rats. Journal of peptide science : an official publication of the European Peptide Society. 2013 May; 19(5):268-76. doi: 10.1002/psc.2495. [PMID: 23532834]
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  • Olinda Almeida, Magdalena Gozdowska, Ewa Kulczykowska, Rui F Oliveira. Brain levels of arginine-vasotocin and isotocin in dominant and subordinate males of a cichlid fish. Hormones and behavior. 2012 Feb; 61(2):212-7. doi: 10.1016/j.yhbeh.2011.12.008. [PMID: 22206822]
  • Radha Chaube, Rahul K Singh, Keerikkattil P Joy. Estrogen regulation of brain vasotocin secretion in the catfish Heteropneustes fossilis: an interaction with catecholaminergic system. General and comparative endocrinology. 2012 Jan; 175(1):206-13. doi: 10.1016/j.ygcen.2011.11.012. [PMID: 22138221]
  • H Bobby Fokidis, Pierre Deviche. Brain arginine vasotocin immunoreactivity differs between urban and desert curve-billed thrashers, Toxostoma curvirostre: relationships with territoriality and stress physiology. Brain, behavior and evolution. 2012; 79(2):84-97. doi: 10.1159/000332766. [PMID: 22067598]
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