4-Amino-2,2,6,6-tetramethylpiperidine 1-oxide (BioDeep_00001028593)

   


代谢物信息卡片


4-Amino-2,2,6,6-tetramethylpiperidine 1-oxide

化学式: C9H19N2O (171.14973039999998)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1(CC(CC(N1[O])(C)C)N)C
InChI: InChI=1S/C9H19N2O/c1-8(2)5-7(10)6-9(3,4)11(8)12/h7H,5-6,10H2,1-4H3

描述信息

同义名列表

1 个代谢物同义名

4-Amino-2,2,6,6-tetramethylpiperidine 1-oxide



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

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PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Sophie Maiocchi, Jacqueline Ku, Tom Hawtrey, Irene De Silvestro, Ernst Malle, Martin Rees, Shane R Thomas, Jonathan C Morris. Polyamine-Conjugated Nitroxides Are Efficacious Inhibitors of Oxidative Reactions Catalyzed by Endothelial-Localized Myeloperoxidase. Chemical research in toxicology. 2021 06; 34(6):1681-1692. doi: 10.1021/acs.chemrestox.1c00094. [PMID: 34085520]
  • Monika Pichla, Grzegorz Bartosz, Natalia Pieńkowska, Izabela Sadowska-Bartosz. Possible artefacts of antioxidant assays performed in the presence of nitroxides and nitroxide-containing nanoparticles. Analytical biochemistry. 2020 05; 597(?):113698. doi: 10.1016/j.ab.2020.113698. [PMID: 32222539]
  • Tracey B Kajer, Kathryn E Fairfull-Smith, Toshihide Yamasaki, Ken-ichi Yamada, Shanlin Fu, Steven E Bottle, Clare L Hawkins, Michael J Davies. Inhibition of myeloperoxidase- and neutrophil-mediated oxidant production by tetraethyl and tetramethyl nitroxides. Free radical biology & medicine. 2014 May; 70(?):96-105. doi: 10.1016/j.freeradbiomed.2014.02.011. [PMID: 24566469]
  • J Czepas, A Koceva-Chyła, K Gwoździński, Z Jóźwiak. Different effectiveness of piperidine nitroxides against oxidative stress induced by doxorubicin and hydrogen peroxide. Cell biology and toxicology. 2008 Jan; 24(1):101-12. doi: 10.1007/s10565-007-9020-3. [PMID: 17610030]
  • Jianfei Jiang, Igor Kurnikov, Natalia A Belikova, Jingbo Xiao, Qing Zhao, Andrew A Amoscato, Rebecca Braslau, Armido Studer, Mitchell P Fink, Joel S Greenberger, Peter Wipf, Valerian E Kagan. Structural requirements for optimized delivery, inhibition of oxidative stress, and antiapoptotic activity of targeted nitroxides. The Journal of pharmacology and experimental therapeutics. 2007 Mar; 320(3):1050-60. doi: 10.1124/jpet.106.114769. [PMID: 17179468]
  • Veronica Wasserman, Pablo Kizelsztein, Olga Garbuzenko, Ron Kohen, Haim Ovadia, Rinat Tabakman, Yechezkel Barenholz. The antioxidant tempamine: in vitro antitumor and neuroprotective effects and optimization of liposomal encapsulation and release. Langmuir : the ACS journal of surfaces and colloids. 2007 Feb; 23(4):1937-47. doi: 10.1021/la060218k. [PMID: 17279678]
  • Carlos A Macias, Jeffrey W Chiao, Jingbo Xiao, Devinder S Arora, Yulia Y Tyurina, Russell L Delude, Peter Wipf, Valerian E Kagan, Mitchell P Fink. Treatment with a novel hemigramicidin-TEMPO conjugate prolongs survival in a rat model of lethal hemorrhagic shock. Annals of surgery. 2007 Feb; 245(2):305-14. doi: 10.1097/01.sla.0000236626.57752.8e. [PMID: 17245186]
  • Agnieszka Marczak, Aleksandra Kowalczyk, Agata Wrzesień-Kus, Tadeusz Robak, Zofia Jóźwiak. Interaction of doxorubicin and idarubicin with red blood cells from acute myeloid leukaemia patients. Cell biology international. 2006 Feb; 30(2):127-32. doi: 10.1016/j.cellbi.2005.09.001. [PMID: 16271486]
  • Boris V Trubitsin, Alexander N Tikhonov. Determination of a transmembrane pH difference in chloroplasts with a spin label tempamine. Journal of magnetic resonance (San Diego, Calif. : 1997). 2003 Aug; 163(2):257-69. doi: 10.1016/s1090-7807(03)00110-1. [PMID: 12914841]
  • C Kroll, A Langner, H H Borchert. Nitroxide metabolism in the human keratinocyte cell line HaCaT. Free radical biology & medicine. 1999 Apr; 26(7-8):850-7. doi: 10.1016/s0891-5849(98)00268-8. [PMID: 10232828]
  • F T Greenaway, C Y O'Gara, J M Marchena, J W Poku, J G Urtiaga, Y Zou. EPR studies of spin-labeled bovine plasma amine oxidase: the nature of the substrate-binding site. Archives of biochemistry and biophysics. 1991 Mar; 285(2):291-6. doi: 10.1016/0003-9861(91)90362-m. [PMID: 1654770]
  • P D Morse, J A Warth. Direct measurement of the internal viscosity of sickle erythrocytes as a function of cell density. Biochimica et biophysica acta. 1990 Jun; 1053(1):49-55. doi: 10.1016/0167-4889(90)90025-9. [PMID: 2163686]
  • M Jay, S M Stuart, C J McClain, D A Palmieri, D A Butterfield. Alternations in lipid membrane fluidity and the physical state of cell-surface sialic acid in zinc-deficient rat erythrocyte ghosts. Biochimica et biophysica acta. 1987 Mar; 897(3):507-11. doi: 10.1016/0005-2736(87)90449-4. [PMID: 3028487]
  • M W Peters, K R Barber, C W Grant. Headgroup behaviour of an uncharged complex glycolipid. Biochimica et biophysica acta. 1982 Dec; 693(2):417-24. doi: 10.1016/0005-2736(82)90449-7. [PMID: 6297558]