Cyclo(N-methyl-L-alanyl-beta-alanyl-(2R)-2-hydroxy-4-pentenoyl-L-prolyl-L-isoleucyl-N-methyl-L-valyl) (BioDeep_00001028545)
代谢物信息卡片
化学式: C29H47N5O7 (577.3475312)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCC(C)C1C(=O)N(C(C(=O)N(C(C(=O)NCCC(=O)OC(C(=O)N2CCCC2C(=O)N1)CC=C)C)C)C(C)C)C
InChI: InChI=1S/C29H47N5O7/c1-9-12-21-27(38)34-16-11-13-20(34)26(37)31-23(18(5)10-2)28(39)33(8)24(17(3)4)29(40)32(7)19(6)25(36)30-15-14-22(35)41-21/h9,17-21,23-24H,1,10-16H2,2-8H3,(H,30,36)(H,31,37)/t18-,19-,20-,21+,23-,24-/m0/s1
描述信息
D010575 - Pesticides > D007306 - Insecticides
D016573 - Agrochemicals
同义名列表
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
3 个相关的物种来源信息
- 5530 - Metarhizium anisopliae:
- 1076431 - Metarhizium indigoticum: 10.1016/J.TETLET.2011.10.013
- 47278 - Trichothecium roseum: 10.7164/ANTIBIOTICS.50.1007
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Jingjing Wang, Hongwang Hu, Suyun Pang, Xuyu Yin, Bihao Cao, Jilei Huang, Xiaoli Xu, Qunfang Weng, Qiongbo Hu. Destruxin A inhibits the hemocytin-mediated hemolymph immunity of host insects to facilitate Metarhizium infection.
Cell reports.
2024 Jan; 43(2):113686. doi:
10.1016/j.celrep.2024.113686. [PMID: 38219149] - Hongwang Hu, Xuyu Yin, Suyun Pang, Yali Jiang, Qunfang Weng, Qiongbo Hu, Jingjing Wang. Mechanism of destruxin a inhibits juvenile hormone binding protein transporting juvenile hormone to affect insect growth.
Pesticide biochemistry and physiology.
2023 Dec; 197(?):105654. doi:
10.1016/j.pestbp.2023.105654. [PMID: 38072529] - Jingjing Wang, Qunfang Weng, Ke Zhang, Qiongbo Hu. Binding proteins of destruxin A from Metarhizium against insect cell.
BMC microbiology.
2023 04; 23(1):96. doi:
10.1186/s12866-023-02843-8. [PMID: 37016280] - Xuyu Yin, Haitao Peng, Qunfang Weng, Qiongbo Hu, Jingjing Wang. Interaction of Destruxin A with Three Silkworm Proteins: BmCRT, BmDPP3, and BmPDIA5.
Molecules (Basel, Switzerland).
2022 Nov; 27(22):. doi:
10.3390/molecules27227713. [PMID: 36431809] - Pengfei Han, Qitian Gong, Jiqiao Fan, Mureed Abbas, Duo Chen, Jianzhen Zhang. Destruxin A inhibits scavenger receptor B mediated melanization in Aphis citricola.
Pest management science.
2022 May; 78(5):1915-1924. doi:
10.1002/ps.6809. [PMID: 35080798] - Muhammad Shakeel, Xiaoxia Xu, Jin Xu, Xun Zhu, Shuzhong Li, Xianqiang Zhou, Jialin Yu, Xiaojing Xu, Qiongbo Hu, Xiaoqiang Yu, Fengliang Jin. Identification of immunity-related genes in Plutella xylostella in response to fungal peptide destruxin A: RNA-Seq and DGE analysis.
Scientific reports.
2017 09; 7(1):10966. doi:
10.1038/s41598-017-11298-7. [PMID: 28887550] - Cong Dong, Jiuru Yu, Ying Zhu, Changjin Dong. Inhibition of hepatitis B virus gene expression & replication by crude destruxins from Metarhizium anisopliae var. dcjhyium.
The Indian journal of medical research.
2013 Dec; 138(6):969-76. doi:
NULL. [PMID: 24521644] - Chengshu Wang, Anke Skrobek, Tariq M Butt. Concurrence of losing a chromosome and the ability to produce destruxins in a mutant of Metarhizium anisopliae.
FEMS microbiology letters.
2003 Sep; 226(2):373-8. doi:
10.1016/s0378-1097(03)00640-2. [PMID: 14553935] - M Soledade C Pedras, L Irina Zaharia, Dale E Ward. The destruxins: synthesis, biosynthesis, biotransformation, and biological activity.
Phytochemistry.
2002 Mar; 59(6):579-96. doi:
10.1016/s0031-9422(02)00016-x. [PMID: 11867090] - A R Bandani, B Amiri, T M Butt, R Gordon-Weeks. Effects of efrapeptin and destruxin, metabolites of entomogenous fungi, on the hydrolytic activity of a vacuolar type ATPase identified on the brush border membrane vesicles of Galleria mellonella midgut and on plant membrane bound hydrolytic enzymes.
Biochimica et biophysica acta.
2001 Feb; 1510(1-2):367-77. doi:
10.1016/s0005-2736(00)00370-9. [PMID: 11342173] - A Tsunoo, M Kamijo. Non-cyclic AMP-dependent, positive inotropic cyclodepsipeptides with negative chronotropy.
The Journal of pharmacology and experimental therapeutics.
1999 Sep; 290(3):1006-12. doi:
. [PMID: 10454471]