(Z)-7-[(1R,2R,3S,5S)-2-[(E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxyprop-1-enyl]-3-fluoro-5-hydroxycyclopentyl]hept-5-enoic acid (BioDeep_00001028537)
代谢物信息卡片
化学式: C24H31FO4 (402.2206)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1C(C(C(C1F)C=CC(C2CC3=CC=CC=C3C2)O)CC=CCCCC(=O)O)O
InChI: InChI=1S/C24H31FO4/c25-21-15-23(27)20(9-3-1-2-4-10-24(28)29)19(21)11-12-22(26)18-13-16-7-5-6-8-17(16)14-18/h1,3,5-8,11-12,18-23,26-27H,2,4,9-10,13-15H2,(H,28,29)/b3-1-,12-11+/t19-,20-,21+,22+,23+/m1/s1
描述信息
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists > D011448 - Prostaglandin Antagonists
同义名列表
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Lauren L Nicotra, Megan Vu, Benjamin S Harvey, Scott D Smid. Prostaglandin ethanolamides attenuate damage in a human explant colitis model.
Prostaglandins & other lipid mediators.
2013 Jan; 100-101(?):22-9. doi:
10.1016/j.prostaglandins.2013.01.003. [PMID: 23380599] - Benjamin J Belda, Jerry T Thompson, Raghu Sinha, K Sandeep Prabhu, John P Vanden Heuvel. The dietary fatty acid 10E12Z-CLA induces epiregulin expression through COX-2 dependent PGF(2α) synthesis in adipocytes.
Prostaglandins & other lipid mediators.
2012 Oct; 99(1-2):30-7. doi:
10.1016/j.prostaglandins.2012.05.001. [PMID: 22583689] - John Cuppoletti, Danuta H Malinowska, Kirti P Tewari, Jayati Chakrabarti, Ryuji Ueno. Unoprostone isopropyl and metabolite M1 activate BK channels and prevent ET-1-induced [Ca²⁺]i increases in human trabecular meshwork and smooth muscle.
Investigative ophthalmology & visual science.
2012 Aug; 53(9):5178-89. doi:
10.1167/iovs.11-9046. [PMID: 22786902] - Eugénie Goupil, Veronica Wisehart, Etienne Khoury, Brandon Zimmerman, Sahar Jaffal, Terence E Hébert, Stéphane A Laporte. Biasing the prostaglandin F2α receptor responses toward EGFR-dependent transactivation of MAPK.
Molecular endocrinology (Baltimore, Md.).
2012 Jul; 26(7):1189-202. doi:
10.1210/me.2011-1245. [PMID: 22638073] - Ko Fujimori, Fumio Amano. Niacin promotes adipogenesis by reducing production of anti-adipogenic PGF2α through suppression of C/EBPβ-activated COX-2 expression.
Prostaglandins & other lipid mediators.
2011 Apr; 94(3-4):96-103. doi:
10.1016/j.prostaglandins.2011.01.002. [PMID: 21236357] - Curtis R Kelly, Gary W Williams, Najam A Sharif. Real-time intracellular Ca2+ mobilization by travoprost acid, bimatoprost, unoprostone, and other analogs via endogenous mouse, rat, and cloned human FP prostaglandin receptors.
The Journal of pharmacology and experimental therapeutics.
2003 Jan; 304(1):238-45. doi:
10.1124/jpet.102.042556. [PMID: 12490597] - N A Sharif, G W Williams, C R Kelly. Bimatoprost and its free acid are prostaglandin FP receptor agonists.
European journal of pharmacology.
2001 Dec; 432(2-3):211-3. doi:
10.1016/s0014-2999(01)01486-8. [PMID: 11740958]
