Macrocyclon (BioDeep_00001028372)
代谢物信息卡片
Macrocyclon
化学式: C17H28O3 (280.2038338)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)(C)CC(C)(C)C1=CC=C(C=C1)O.C=O.C1CO1
InChI: 1H2
描述信息
R - Respiratory system > R05 - Cough and cold preparations > R05C - Expectorants, excl. combinations with cough suppressants > R05CA - Expectorants
D013501 - Surface-Active Agents > D011092 - Polyethylene Glycols
D013501 - Surface-Active Agents > D003902 - Detergents
D001697 - Biomedical and Dental Materials
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Adil Qabouche, Ayoub Amssayef, Ismail Bouadid, Nadia Lahrach, Ahmed El-Haidani, Mohamed Eddouks. Antidiabetic and Antidyslipidemic Effects of Artemisia mesatlantica, an Endemic Plant from Morocco.
Cardiovascular & hematological disorders drug targets.
2023 Aug; ?(?):. doi:
10.2174/1871529x23666230803113616. [PMID: 37534785] - Imane Mokhtari, Chakib Mokhtari, Mohammadine Moumou, Mohamed Harnafi, Dragan Milenkovic, Souliman Amrani, Abdelmalek Hakmaoui, Hicham Harnafi. Polyphenol-rich extract from loquat fruit peel prevents hyperlipidemia and hepato-nephrotoxicity in mice: in vivo study and in silico prediction of possible mechanisms involving identified polyphenols and/or their circulating metabolites.
Food & function.
2023 Jul; ?(?):. doi:
10.1039/d3fo01992f. [PMID: 37498560] - Xiaoping Ji, Qianqian Ma, Xuan Wang, Hui Ming, Guihua Bao, Minghai Fu, Chengxi Wei. Digeda-4 decoction and its disassembled prescriptions improve dyslipidemia and apoptosis by regulating AMPK/SIRT1 pathway on tyloxapol-induced nonalcoholic fatty liver disease in mice.
Journal of ethnopharmacology.
2023 Jun; 317(?):116827. doi:
10.1016/j.jep.2023.116827. [PMID: 37348794] - Hao Yu, Siru Yan, Meiyu Jin, Yunfei Wei, Lilei Zhao, Jiaqi Cheng, Lu Ding, Haihua Feng. Aescin can alleviate NAFLD through Keap1-Nrf2 by activating antioxidant and autophagy.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2023 May; 113(?):154746. doi:
10.1016/j.phymed.2023.154746. [PMID: 36905866] - Guanlin Xiao, Zixuan Hu, Canchao Jia, Minjuan Yang, Dongmei Li, Aili Xu, Jieyi Jiang, Zhao Chen, Yangxue Li, Sumei Li, Weitao Chen, Jingnian Zhang, Xiaoli Bi. Deciphering the mechanisms of Yinlan Tiaozhi capsule in treating hyperlipidemia by combining network pharmacology, molecular docking and experimental verification.
Scientific reports.
2023 04; 13(1):6424. doi:
10.1038/s41598-023-33673-3. [PMID: 37076581] - Esra Palabıyık, Ayşe Nurseli Sulumer, Handan Uguz, Bahri Avcı, Seda Askın, Hakan Askın, Yeliz Demir. Assessment of hypolipidemic and anti-inflammatory properties of walnut (Juglans regia) seed coat extract and modulates some metabolic enzymes activity in triton WR-1339-induced hyperlipidemia in rat kidney, liver, and heart.
Journal of molecular recognition : JMR.
2023 Mar; 36(3):e3004. doi:
10.1002/jmr.3004. [PMID: 36537558] - Bingyu Shen, Yeling Wang, Jiaqi Cheng, Yi Peng, Qiaoling Zhang, Zheng Li, Lilei Zhao, Xuming Deng, Haihua Feng. Pterostilbene alleviated NAFLD via AMPK/mTOR signaling pathways and autophagy by promoting Nrf2.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2023 Jan; 109(?):154561. doi:
10.1016/j.phymed.2022.154561. [PMID: 36610156] - Meiyu Jin, Di Zhang, Lianwen Zheng, Yunfei Wei, Siru Yan, Haiyan Qin, Qi Wang, Lilei Zhao, Haihua Feng. Lipopolysaccharide and tyloxapol accelerate the development of atherosclerosis in mice.
Lipids.
2022 03; 57(2):83-90. doi:
10.1002/lipd.12331. [PMID: 34875723] - Letícia Pereira Afonso Ramos, Allisson Benatti Justino, Natália Tavernelli, André Lopes Saraiva, Rodrigo Rodrigues Franco, Adriele Vieira de Souza, Heitor Cappato Guerra Silva, Francyelle Borges Rosa de Moura, Françoise Vasconcelos Botelho, Foued Salmen Espindola. Antioxidant compounds from Annona crassiflora fruit peel reduce lipid levels and oxidative damage and maintain the glutathione defense in hepatic tissue of Triton WR-1339-induced hyperlipidemic mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2021 Oct; 142(?):112049. doi:
10.1016/j.biopha.2021.112049. [PMID: 34426250] - Yundong Xie, Jiping Liu, Yongheng Shi, Bin Wang, Xiaoping Wang, Wei Wang, Meng Sun, Xinya Xu, Haihui Jiang, Min Guo, Yiyi He, Cuicui Ren, Lifei Cheng. The combination of sesamol and clofibric acid moieties leads to a novel potent hypolipidemic agent with antioxidant, anti-inflammatory and hepatoprotective activity.
Bioorganic & medicinal chemistry letters.
2021 07; 44(?):128121. doi:
10.1016/j.bmcl.2021.128121. [PMID: 34015506] - Eimad Dine Tariq Bouhlali, Abdelbasset Hmidani, Bouchra Bourkhis, Tarik Khouya, Hicham Harnafi, Younes Filali-Zegzouti, Chakib Alem. Effect of Phoenix dactylifera seeds (dates) extract in triton WR-1339 and high fat diet induced hyperlipidaemia in rats: A comparison with simvastatin.
Journal of ethnopharmacology.
2020 Sep; 259(?):112961. doi:
10.1016/j.jep.2020.112961. [PMID: 32423881] - Bingyu Shen, Haihua Feng, Jiaqi Cheng, Zheng Li, Meiyu Jin, Lilei Zhao, Qi Wang, Haiyan Qin, Guowen Liu. Geniposide alleviates non-alcohol fatty liver disease via regulating Nrf2/AMPK/mTOR signalling pathways.
Journal of cellular and molecular medicine.
2020 05; 24(9):5097-5108. doi:
10.1111/jcmm.15139. [PMID: 32293113] - Yuting Li, Yuxing Chen, Xuejun Huang, Dane Huang, Haining Gan, Nan Yao, Zixuan Hu, Ruyue Li, Xinyi Zhan, Kaifeng Xie, Jieyi Jiang, Dake Cai. Tanshinol A Ameliorates Triton-1339W-Induced Hyperlipidemia and Liver Injury in C57BL/6J Mice by Regulating mRNA Expression of Lipemic-Oxidative Injury Genes.
Lipids.
2020 03; 55(2):127-140. doi:
10.1002/lipd.12217. [PMID: 32058595] - Suélen Osório Heck, Vanessa Angonesi Zborowski, Pietro Maria Chagas, Sônia Cristina Almeida da Luz, Cristiani Folharini Bortolatto. p-Chloro-diphenyl diselenide attenuates plasma lipid profile changes and hepatotoxicity induced by nonionic surfactant tyloxapol in rats.
Toxicology mechanisms and methods.
2020 Jan; 30(1):73-80. doi:
10.1080/15376516.2019.1669240. [PMID: 31532275] - - Ruqqia, Nida Sohail, Darakhshan Taj, Ghulam Sarwar, Viqar Sultana, Jehan Ara, Syed Ehteshamul Haque. Hypolipidemic potential of sterol containing fractions of Jolyna laminarioides: a brown alga.
Pakistan journal of pharmaceutical sciences.
2020 Jan; 33(1):169-174. doi:
. [PMID: 32122845] - Lin Wu, Yue Wang, Gefu Chi, Bingyu Shen, Ye Tian, Zheng Li, Lu Han, Qiaoling Zhang, Haihua Feng. Morin reduces inflammatory responses and alleviates lipid accumulation in hepatocytes.
Journal of cellular physiology.
2019 11; 234(11):19785-19798. doi:
10.1002/jcp.28578. [PMID: 30937936] - Rihab Khlifi, Aida Lahmar, Zaineb Dhaouefi, Zahar Kalboussi, Mouna Maatouk, Soumaya Kilani-Jaziri, Kamel Ghedira, Leila Chekir-Ghedira. Assessment of hypolipidemic, anti-inflammatory and antioxidant properties of medicinal plant Erica multiflora in triton WR-1339-induced hyperlipidemia and liver function repair in rats: A comparison with fenofibrate.
Regulatory toxicology and pharmacology : RTP.
2019 Oct; 107(?):104404. doi:
10.1016/j.yrtph.2019.104404. [PMID: 31199997] - Martina Theresa Hackl, Clemens Fürnsinn, Christina Maria Schuh, Martin Krssak, Fabrizia Carli, Sara Guerra, Angelika Freudenthaler, Sabina Baumgartner-Parzer, Thomas H Helbich, Anton Luger, Maximilian Zeyda, Amalia Gastaldelli, Christoph Buettner, Thomas Scherer. Brain leptin reduces liver lipids by increasing hepatic triglyceride secretion and lowering lipogenesis.
Nature communications.
2019 06; 10(1):2717. doi:
10.1038/s41467-019-10684-1. [PMID: 31222048] - Ting Zhang, Qi Zhao, Xuerong Xiao, Rui Yang, Dandan Hu, Xu Zhu, Frank J Gonzalez, Fei Li. Modulation of Lipid Metabolism by Celastrol.
Journal of proteome research.
2019 03; 18(3):1133-1144. doi:
10.1021/acs.jproteome.8b00797. [PMID: 30706713] - Jiake He, Ge Zhang, Qiuyang Zhang, Jiayin Chen, Yongjie Zhang, Xiaoxia An, Pan Wang, Shan Xie, Fang Fang, Jianheng Zheng, Yue Tang, Jiabi Zhu, Yang Yu, Xijing Chen, Yang Lu. Evaluation of inhaled recombinant human insulin dry powders: pharmacokinetics, pharmacodynamics and 14-day inhalation.
The Journal of pharmacy and pharmacology.
2019 Feb; 71(2):176-184. doi:
10.1111/jphp.13026. [PMID: 30324757] - Bhavesh C Variya, Anita K Bakrania, Yuanli Chen, Jihong Han, Snehal S Patel. Suppression of abdominal fat and anti-hyperlipidemic potential of Emblica officinalis: Upregulation of PPARs and identification of active moiety.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2018 Dec; 108(?):1274-1281. doi:
10.1016/j.biopha.2018.09.158. [PMID: 30372828] - Gaurav Garg, Amol Patil, Jagjit Singh, Nutan Kaushik, Ajay Praksah, Arnab Pal, Amitava Chakrabarti. Pharmacological evaluation of Convolvulus pluricaulis as hypolipidaemic agent in Triton WR-1339-induced hyperlipidaemia in rats.
The Journal of pharmacy and pharmacology.
2018 Nov; 70(11):1572-1580. doi:
10.1111/jphp.13004. [PMID: 30182365] - Yun-Dong Xie, Zi-Zhang Chen, Li-Hua Shao, Qiu-Tang Wang, Na Li, Wen-Fang Lu, Yan-Hong Xu, Yu-Qiong Gao, Li-Ying Guo, Hao-Le Liu, Yi-Ping Li, Guang-De Yang, Xiao-Li Bian. A new multifunctional hydroxytyrosol-clofibrate with hypolipidemic, antioxidant, and hepatoprotective effects.
Bioorganic & medicinal chemistry letters.
2018 10; 28(18):3119-3122. doi:
10.1016/j.bmcl.2018.06.010. [PMID: 30119959] - Arun Kumar, Rekha, S K Kansal, A O Ibhadon, S K Mehta. Mixed surfactant (altering chain length and head group) aggregates as an effective carrier for tuberculosis drug.
Chemistry and physics of lipids.
2018 09; 215(?):11-17. doi:
10.1016/j.chemphyslip.2018.07.001. [PMID: 30033376] - Xiaoqi Huang, Xiaoli Wu, Sishan Yan, Tian Lan. [Lipid-lowering effect of propolis in mice with Triton-WR1339-induced hyperlipidemia and its mechanism for regulating lipid metabolism].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University.
2018 Jul; 38(8):1020-1024. doi:
10.3969/j.issn.1673-4254.2018.08.20. [PMID: 30187881] - Ghassan Abu Sheikha, Majdi Mohammad Bkhaitan, Hanin Kalloush, Lama Hamadneh, Reema Abu Khalaf, Tariq Al-Qirim, Yusuf Al-Hiari. Synthesis of Novel Benzimidazole-2-carboxamide Derivatives and in Vivo Antihyperlipidemic Activity Evaluation.
Chemical & pharmaceutical bulletin.
2018; 66(4):423-426. doi:
10.1248/cpb.c17-00908. [PMID: 29607907] - Suhair H Jasim, Ghassan M Abu Sheikha, Haneen M Abuzaid, Tariq M Al-Qirim, Ghassan F Shattat, Dima A Sabbah, Samah A Ata, Samah A Ala, Mustafa S Aboumair, Kamal A Sweidan, Majdi M Bkhaitan. Synthesis and in Vivo Lipid-Lowering Activity of Novel Imidazoles-5-carboxamide Derivatives in Triton-WR-1339-Induced Hyperlipidemic Wistar Rats.
Chemical & pharmaceutical bulletin.
2018; 66(10):953-958. doi:
10.1248/cpb.c18-00346. [PMID: 30270241] - Vishal Patel, Amit Joharapurkar, Samadhan Kshirsagar, Hiren M Patel, Dheerendra Pandey, Dipam Patel, Brijesh Sutariya, Maulik Patel, Rajesh Bahekar, Mukul R Jain. Balanced Coagonist of GLP-1 and Glucagon Receptors Corrects Dyslipidemia by Improving FGF21 Sensitivity in Hamster Model.
Drug research.
2017 Dec; 67(12):730-736. doi:
10.1055/s-0043-118808. [PMID: 28898910] - Matheus D Baldissera, Carine F Souza, Pedro H Doleski, Daniela B R Leal, Lenita M Stefani, Aline A Boligon, Silvia G Monteiro. Enzymes that hydrolyze adenine nucleotides in a model of hypercholesterolemia induced by Triton WR-1339: protective effects of β-caryophyllene.
Molecular and cellular biochemistry.
2017 Oct; 434(1-2):127-134. doi:
10.1007/s11010-017-3042-9. [PMID: 28432556] - Joubert Aires de Sousa, Patrícia Pereira, Mariangela da Costa Allgayer, Norma Possa Marroni, Alexandre de Barros Falcão Ferraz, Jaqueline Nascimento Picada. Evaluation of DNA damage in Wistar rat tissues with hyperlipidemia induced by tyloxapol.
Experimental and molecular pathology.
2017 08; 103(1):51-55. doi:
10.1016/j.yexmp.2017.06.009. [PMID: 28684216] - Lama Hamadneh, Luay Al-Essa, Suhair Hikmat, Tariq Al-Qirim, Ghassan Abu Sheikha, Yusuf Al-Hiari, Nisrin Azmy, Ghassan Shattat. N-(3-Benzoylphenyl)-1H-Indole-2-Carboxamide decreases triglyceride levels by downregulation of Apoc3 gene expression in acute hyperlipidemic rat model.
Molecular and cellular biochemistry.
2017 Jul; 431(1-2):133-138. doi:
10.1007/s11010-017-2983-3. [PMID: 28255847] - Matheus D Baldissera, Carine F Souza, Thirssa H Grando, Lenita M Stefani, Silvia G Monteiro. β-caryophyllene reduces atherogenic index and coronary risk index in hypercholesterolemic rats: The involvement of cardiac oxidative damage.
Chemico-biological interactions.
2017 May; 270(?):9-14. doi:
10.1016/j.cbi.2017.04.008. [PMID: 28411027] - Erenius Toppo, S Sylvester Darvin, S Esakkimuthu, A Stalin, K Balakrishna, K Sivasankaran, P Pandikumar, S Ignacimuthu, N A Al-Dhabi. Antihyperlipidemic and hepatoprotective effects of Gardenin A in cellular and high fat diet fed rodent models.
Chemico-biological interactions.
2017 May; 269(?):9-17. doi:
10.1016/j.cbi.2017.03.013. [PMID: 28351695] - Umakant Ashok Bahirat, Rekha Raghuveer Shenoy, Rajan Naresh Goel, Kumar V S Nemmani. APD668, a G protein-coupled receptor 119 agonist improves fat tolerance and attenuates fatty liver in high-trans fat diet induced steatohepatitis model in C57BL/6 mice.
European journal of pharmacology.
2017 Apr; 801(?):35-45. doi:
10.1016/j.ejphar.2017.02.043. [PMID: 28274625] - Poovathumkal James Antony, Gopalsamy Rajiv Gandhi, Antony Stalin, Kedike Balakrishna, Erenius Toppo, Kuppusamy Sivasankaran, Savarimuthu Ignacimuthu, Naif Abdullah Al-Dhabi. Myoinositol ameliorates high-fat diet and streptozotocin-induced diabetes in rats through promoting insulin receptor signaling.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2017 Apr; 88(?):1098-1113. doi:
10.1016/j.biopha.2017.01.170. [PMID: 28192884] - Diana Patricia Moreno-Pena, Paula Cordero-Pérez, Catalina Leos-Rivas, Leticia Bucio, Jose Ezequiel Viveros-Valdez, Linda Elsa Munoz-Espinosa, Sergio Arturo Galindo-Rodríguez, Catalina Rivas-Morales. Evaluation of hypocholesterolemic activity of extracts of Bidens odorata and Brickellia eupatorioides.
Pakistan journal of pharmaceutical sciences.
2017 Mar; 30(2(Suppl.)):613-617. doi:
". [PMID: 28650330] - Matheus D Baldissera, Carine F Souza, Thirssa H Grando, Pedro H Doleski, Aline A Boligon, Lenita M Stefani, Silvia G Monteiro. Hypolipidemic effect of β-caryophyllene to treat hyperlipidemic rats.
Naunyn-Schmiedeberg's archives of pharmacology.
2017 Feb; 390(2):215-223. doi:
10.1007/s00210-016-1326-3. [PMID: 27913825] - Divya Suares, Bala Prabhakar. Cuboidal lipid polymer nanoparticles of rosuvastatin for oral delivery.
Drug development and industrial pharmacy.
2017 Feb; 43(2):213-224. doi:
10.1080/03639045.2016.1232726. [PMID: 27593545] - Patrícia Rosane Leite de Figueiredo, Isabella Bezerra Oliveira, José Benício Santana Neto, Juliana Albuquerque de Oliveira, Larissa Bernardo Ribeiro, Glauce Socorro de Barros Viana, Talita Magalhães Rocha, Luzia Kalyne Almeida Moreira Leal, Marta Regina Kerntopf, Cícero Francisco Bezerra Felipe, Henrique Douglas Melo Coutinho, Irwin Rose de Alencar Menezes. Caryocar coriaceum Wittm. (Pequi) fixed oil presents hypolipemic and anti-inflammatory effects in vivo and in vitro.
Journal of ethnopharmacology.
2016 Sep; 191(?):87-94. doi:
10.1016/j.jep.2016.06.038. [PMID: 27321275] - Yang Li, Zheng Li, Lei Shi, Chenxu Zhao, Bingyu Shen, Ye Tian, Haihua Feng. Loganin inhibits the inflammatory response in mouse 3T3L1 adipocytes and mouse model.
International immunopharmacology.
2016 Jul; 36(?):173-179. doi:
10.1016/j.intimp.2016.04.026. [PMID: 27155393] - L Ivry Del Moral, L Le Corre, H Poirier, I Niot, T Truntzer, J-F Merlin, P Rouimi, P Besnard, R Rahmani, M C Chagnon. Obesogen effects after perinatal exposure of 4,4'-sulfonyldiphenol (Bisphenol S) in C57BL/6 mice.
Toxicology.
2016 05; 357-358(?):11-20. doi:
10.1016/j.tox.2016.05.023. [PMID: 27241191] - Aliasghar Chalmeh, Alireza Rahmani Shahraki, Seyed Mohammad Mehdi Heidari, Khalil Badiei, Mehrdad Pourjafar, Saeed Nazifi, Mohammad Javad Zamiri. The comparative efficacy of tyloxapol versus pentoxifylline against induced acute phase response in an ovine experimental endotoxemia model.
Inflammopharmacology.
2016 Feb; 24(1):59-64. doi:
10.1007/s10787-015-0257-9. [PMID: 26721797] - Rana Abu Farha, Yasser Bustanji, Yusuf Al-Hiari, Tariq Al-Qirim, Ghassan Abu Shiekha, Rabab Albashiti. Lipid lowering activity of novel N-(benzoylphenyl)pyridine-3-carboxamide derivatives in Triton WR-1339-induced hyperlipidemic rats.
Journal of enzyme inhibition and medicinal chemistry.
2016; 31(sup4):138-144. doi:
10.1080/14756366.2016.1222581. [PMID: 27558168] - Luiz Carlos S Porto, Juliana da Silva, Alexandre B F Ferraz, Eduardo M Ethur, Caroline D L Porto, Norma P Marroni, Jaqueline N Picada. The Antidiabetic and Antihypercholesterolemic Effects of an Aqueous Extract from Pecan Shells in Wistar Rats.
Plant foods for human nutrition (Dordrecht, Netherlands).
2015 Dec; 70(4):414-9. doi:
10.1007/s11130-015-0510-9. [PMID: 26449221] - Panagiotis Theodosis-Nobelos, Malamati Kourti, Paraskevi Tziona, Panos N Kourounakis, Eleni A Rekka. Esters of some non-steroidal anti-inflammatory drugs with cinnamyl alcohol are potent lipoxygenase inhibitors with enhanced anti-inflammatory activity.
Bioorganic & medicinal chemistry letters.
2015 Nov; 25(22):5028-31. doi:
10.1016/j.bmcl.2015.10.036. [PMID: 26494261] - Kyriaki-Konstantina Tooulia, Panagiotis Theodosis-Nobelos, Eleni A Rekka. Thiomorpholine Derivatives with Hypolipidemic and Antioxidant Activity.
Archiv der Pharmazie.
2015 Sep; 348(9):629-34. doi:
10.1002/ardp.201500147. [PMID: 26191791] - Eduardo Padilla-Camberos, Jose Miguel Flores-Fernandez, Ofelia Fernandez-Flores, Yanet Gutierrez-Mercado, Joel Carmona-de la Luz, Fabiola Sandoval-Salas, Carlos Mendez-Carreto, Kirk Allen. Hypocholesterolemic Effect and In Vitro Pancreatic Lipase Inhibitory Activity of an Opuntia ficus-indica Extract.
BioMed research international.
2015; 2015(?):837452. doi:
10.1155/2015/837452. [PMID: 26078966] - Humaira Jamshed, Anwar H Gilani. Almonds inhibit dyslipidemia and vascular dysfunction in rats through multiple pathways.
The Journal of nutrition.
2014 Nov; 144(11):1768-74. doi:
10.3945/jn.114.198721. [PMID: 25332475] - Koneni V Sashidhara, Ranga Prasad Dodda, Ravi Sonkar, Gopala Reddy Palnati, Gitika Bhatia. Design and synthesis of novel indole-chalcone fibrates as lipid lowering agents.
European journal of medicinal chemistry.
2014 Jun; 81(?):499-509. doi:
10.1016/j.ejmech.2014.04.085. [PMID: 24871900] - Sunil K Mishra, Shashi Tiwari, Atul Shrivastava, Shishir Srivastava, Goutam K Boudh, Shivendra K Chourasia, Upma Chaturvedi, Snober S Mir, Anil K Saxena, Gitika Bhatia, Vijai Lakshmi. Antidyslipidemic effect and antioxidant activity of anthraquinone derivatives from Rheum emodi rhizomes in dyslipidemic rats.
Journal of natural medicines.
2014 Apr; 68(2):363-71. doi:
10.1007/s11418-013-0810-z. [PMID: 24343839] - Sung-Pil Jo, Jeong-Keun Kim, Young-Hee Lim. Antihyperlipidemic effects of stilbenoids isolated from Morus alba in rats fed a high-cholesterol diet.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2014 Mar; 65(?):213-8. doi:
10.1016/j.fct.2013.12.040. [PMID: 24407019] - K A Rony, T A Ajith, N Nima, K K Janardhanan. Hypolipidemic activity of Phellinus rimosus against triton WR-1339 and high cholesterol diet induced hyperlipidemic rats.
Environmental toxicology and pharmacology.
2014 Mar; 37(2):482-92. doi:
10.1016/j.etap.2014.01.004. [PMID: 24561532] - P Ashok, D Singh, D N Poulose, B Suresh. Evaluation of antihyperlipidemic potency of a polyherbomineral formulation (AF-LIP) in experimental animal models.
Pakistan journal of biological sciences : PJBS.
2014 Feb; 17(3):346-55. doi:
10.3923/pjbs.2014.346.355. [PMID: 24897788] - Nan Yao, Rong-rong He, Xiao-hui Zeng, Xue-jun Huang, Tie-liang Du, Jing-chao Cui, Kurihara Hiroshi. Hypotriglyceridemic effects of apple polyphenols extract via up-regulation of lipoprotein lipase in triton WR-1339-induced mice.
Chinese journal of integrative medicine.
2014 Jan; 20(1):31-5. doi:
10.1007/s11655-012-1243-3. [PMID: 23001493] - Deepa Iyer, U K Patil. Evaluation of antihyperlipidemic and antitumor activities of isolated coumarins from Salvadora indica.
Pharmaceutical biology.
2014 Jan; 52(1):78-85. doi:
10.3109/13880209.2013.815633. [PMID: 24073795] - Nauman Aziz, Malik Hassan Mehmood, Anwarul-Hassan Gilani. Studies on two polyherbal formulations (ZPTO and ZTO) for comparison of their antidyslipidemic, antihypertensive and endothelial modulating activities.
BMC complementary and alternative medicine.
2013 Dec; 13(?):371. doi:
10.1186/1472-6882-13-371. [PMID: 24370063] - Nikhilesh Arya, Jaya Dwivedi, Vijay M Khedkar, Evans C Coutinho, Kishor S Jain. Design, synthesis and biological evaluation of some 2-azetidinone derivatives as potential antihyperlipidemic agents.
Archiv der Pharmazie.
2013 Dec; 346(12):872-81. doi:
10.1002/ardp.201300262. [PMID: 24142910] - Deepa Iyer, Brajesh K Sharma, U K Patil. Isolation of bioactive phytoconstituent from Alpinia galanga L. with anti-hyperlipidemic activity.
Journal of dietary supplements.
2013 Dec; 10(4):309-17. doi:
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Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2013 Oct; 60(?):135-40. doi:
10.1016/j.fct.2013.07.035. [PMID: 23891761] - Alessandra dos Santos Danziger Silvério, Rosemary Gualberto Fonseca Alvarenga Pereira, Adriene Ribeiro Lima, Fernanda Borges de Araújo Paula, Maria Rita Rodrigues, Lineu Baldissera, Stella Maris da Silveira Duarte. The effects of the decaffeination of coffee samples on platelet aggregation in hyperlipidemic rats.
Plant foods for human nutrition (Dordrecht, Netherlands).
2013 Sep; 68(3):268-73. doi:
10.1007/s11130-013-0365-x. [PMID: 23780748] - Ghassan Shattat, Tariq Al-Qirim, Ghassan Abu Sheikha, Yusuf Al-Hiari, Kamal Sweidan, Rania Al-Qirim, Suhair Hikmat, Lama Hamadneh, Sameer Al-Kouz. The pharmacological effects of novel 5-fluoro-N-(9,10-dihydro-9,10-dioxoanthracen-8-yl)-1H-indole-2-carboxamide derivatives on plasma lipid profile of Triton-WR-1339-induced Wistar rats.
Journal of enzyme inhibition and medicinal chemistry.
2013 Aug; 28(4):863-9. doi:
10.3109/14756366.2012.692085. [PMID: 22651797] - Nikhilesh Arya, Manoj K Munde, Jaya Dwivedi, Archana Y Jagdale, Kishor S Jain. Design, synthesis, and antihyperlipidemic evaluation of novel 2-[1-(substitutedphenyl)-4-oxo-azetidin-2-yl]-5,6-disubstitutedthieno[2,3-d]pyrimidin-4(3H)-ones.
Archiv der Pharmazie.
2013 Aug; 346(8):588-95. doi:
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Lipids.
2013 Jun; 48(6):597-607. doi:
10.1007/s11745-012-3753-3. [PMID: 23334955] - Koneni V Sashidhara, Gopala Reddy Palnati, Ravi Sonkar, Srinivasa Rao Avula, Chetan Awasthi, Gitika Bhatia. Coumarin chalcone fibrates: a new structural class of lipid lowering agents.
European journal of medicinal chemistry.
2013 Jun; 64(?):422-31. doi:
10.1016/j.ejmech.2013.04.026. [PMID: 23665798] - Ramalingam Anandhi, Thangaraj Annadurai, Thirugnanasambandhar S Anitha, Arumugam R Muralidharan, Kalifulla Najmunnisha, Vasanthi Nachiappan, Philip A Thomas, Pitchairaj Geraldine. Antihypercholesterolemic and antioxidative effects of an extract of the oyster mushroom, Pleurotus ostreatus, and its major constituent, chrysin, in Triton WR-1339-induced hypercholesterolemic rats.
Journal of physiology and biochemistry.
2013 Jun; 69(2):313-23. doi:
10.1007/s13105-012-0215-6. [PMID: 23104078] - Roberto Martínez-Beamonte, María A Navarro, Sergio Acin, Natalia Guillén, Cristina Barranquero, Carmen Arnal, Joaquín Surra, Jesus Osada. Postprandial changes in high density lipoproteins in rats subjected to gavage administration of virgin olive oil.
PloS one.
2013; 8(1):e55231. doi:
10.1371/journal.pone.0055231. [PMID: 23383120] - Panneerselvam Vijayaraj, Kannan Muthukumar, Jayaraja Sabarirajan, Vasanthi Nachiappan. Antihyperlipidemic activity of Cassia auriculata flowers in triton WR 1339 induced hyperlipidemic rats.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.
2013 Jan; 65(1-2):135-41. doi:
10.1016/j.etp.2011.07.001. [PMID: 21852078] - Koneni V Sashidhara, Gopala Reddy Palnati, Ranga Prasad Dodda, Ravi Sonkar, A K Khanna, Gitika Bhatia. Discovery of amide based fibrates as possible antidyslipidemic and antioxidant agents.
European journal of medicinal chemistry.
2012 Nov; 57(?):302-10. doi:
10.1016/j.ejmech.2012.09.040. [PMID: 23078966] - Vincent Frochot, Malik Alqub, Anne-Laure Cattin, Véronique Carrière, Anne Houllier, Floriane Baraille, Laurence Barbot, Susan Saint-Just, Agnès Ribeiro, Michel Lacasa, Philippe Cardot, Jean Chambaz, Monique Rousset, Jean-Marc Lacorte. The transcription factor HNF-4α: a key factor of the intestinal uptake of fatty acids in mouse.
American journal of physiology. Gastrointestinal and liver physiology.
2012 Jun; 302(11):G1253-63. doi:
10.1152/ajpgi.00329.2011. [PMID: 22461026] - Maciej Gawlik, Małgorzata B Gawlik, Jerzy Brandys. The impact of Triton WR-1339 induced hyperlipidemia on the effects of benzo(a)pyrene or guaiacol on α- and γ-tocopherol pools and selected markers of pro-/antioxidative balance in rat plasma and erythrocytes.
Environmental toxicology and pharmacology.
2012 May; 33(3):386-93. doi:
10.1016/j.etap.2012.01.004. [PMID: 22387351] - Tariq Al-Qirim, Ghassan Shattat, Kamal Sweidan, Waseem El-Huneidi, Ghassan Abu Sheikha, Reema Abu Khalaf, Suhair Hikmat. In vivo antihyperlipidemic activity of a new series of N-(benzoylphenyl) and N-(acetylphenyl)-1-benzofuran-2-carboxamides in rats.
Archiv der Pharmazie.
2012 May; 345(5):401-6. doi:
10.1002/ardp.201100225. [PMID: 22266816] - Christudas Sunil, Savarimuthu Ignacimuthu, Chidambaram Kumarappan. Hypolipidemic activity of Symplocos cochinchinensis S. Moore leaves in hyperlipidemic rats.
Journal of natural medicines.
2012 Jan; 66(1):32-8. doi:
10.1007/s11418-011-0548-4. [PMID: 21681640] - M Saravanan, P Pandikumar, N Prakash Babu, S Ignacimuthu. Antihyperlipidemic activity of Ichnocarpus frutescens in triton WR-1339-induced and high-fat diet animals.
Pharmaceutical biology.
2011 Oct; 49(10):1074-81. doi:
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Molecules (Basel, Switzerland).
2011 Sep; 16(10):8292-304. doi:
10.3390/molecules16108292. [PMID: 21959300] - Tatyana A Korolenko, Marina S Cherkanova, Fedor V Tuzikov, Thomas P Johnston, Natalia A Tuzikova, Viktoriya M Loginova, Vassilij I Kaledin. Influence of atorvastatin on fractional and subfractional composition of serum lipoproteins and MMP activity in mice with Triton WR 1339-induced lipaemia.
The Journal of pharmacy and pharmacology.
2011 Jun; 63(6):833-9. doi:
10.1111/j.2042-7158.2011.01287.x. [PMID: 21585382] - Tiago R Figueira, Aníbal E Vercesi, Helena C F Oliveira. Lack of plasma albumin impairs intravascular lipolysis and explains the associated free fatty acids deficiency and hypertriglyceridemia.
Lipids in health and disease.
2010 Dec; 9(?):146. doi:
10.1186/1476-511x-9-146. [PMID: 21187011] - Ghassan Shattat, Tariq Al-Qirim, Kamal Sweidan, Moyad Shahwan, Waseem El-Huneidi, Yusuf Al-Hiari. The hypolipidemic activity of novel benzofuran-2-carboxamide derivatives in Triton WR-1339-induced hyperlipidemic rats: a comparison with bezafibrate.
Journal of enzyme inhibition and medicinal chemistry.
2010 Dec; 25(6):751-5. doi:
10.3109/14756360903389880. [PMID: 20590406] - Jianheng Zheng, Ge Zhang, Yang Lu, Fang Fang, Jiake He, Ning Li, Amer Talbi, Ying Zhang, Yue Tang, Jiabi Zhu, Xijing Chen. Effect of pulmonary surfactant and phospholipid hexadecanol tyloxapol on recombinant human-insulin absorption from intratracheally administered dry powders in diabetic rats.
Chemical & pharmaceutical bulletin.
2010 Dec; 58(12):1612-6. doi:
10.1248/cpb.58.1612. [PMID: 21139264] - T A Korolenko, F V Tuzikov, E D Vasil'eva, M S Cherkanova, N A Tuzikova. Fractional composition of blood serum lipoproteins in mice and rats with Triton WR 1339-induced lipemia.
Bulletin of experimental biology and medicine.
2010 Oct; 149(5):567-70. doi:
10.1007/s10517-010-0994-0. [PMID: 21165388] - Ghassan Shattat, Rania Al-Qirim, Yusuf Al-Hiari, Ghassan Abu Sheikha, Tariq Al-Qirim, Waseem El-Huneidi, Moyad Shahwan. Synthesis and anti-hyperlipidemic evaluation of N‑(benzoylphenyl)-5-fluoro-1H-indole-2-carboxamide derivatives in Triton WR-1339-induced hyperlipidemic rats.
Molecules (Basel, Switzerland).
2010 Aug; 15(9):5840-9. doi:
10.3390/molecules15095840. [PMID: 21330955] - Adejuwon Adewale Adeneye, Olufunmilayo Olaide Adeyemi, Esther Oluwatoyin Agbaje. Anti-obesity and antihyperlipidaemic effect of Hunteria umbellata seed extract in experimental hyperlipidaemia.
Journal of ethnopharmacology.
2010 Jul; 130(2):307-14. doi:
10.1016/j.jep.2010.05.009. [PMID: 20471465] - Bonggi Lee, Angela M Fast, Jiabin Zhu, Ji-Xin Cheng, Kimberly K Buhman. Intestine-specific expression of acyl CoA:diacylglycerol acyltransferase 1 reverses resistance to diet-induced hepatic steatosis and obesity in Dgat1-/- mice.
Journal of lipid research.
2010 Jul; 51(7):1770-80. doi:
10.1194/jlr.m002311. [PMID: 20147738] - Moyad Shahwan, Ghassan Shattat, Tariq Al-Qirim, Ghassan Abu Sheikha, Yusuf Al-Hiari, Waseem El-Huneidi, Anan Jarab, Manal Al-Najdawi. Synthesis and pharmacological evaluation of novel substituted and unsubstituted N-(benzoylphenyl)-1H-indole-2-carboxamides as potent antihypertriglyceridemic agents.
Zeitschrift fur Naturforschung. C, Journal of biosciences.
2010 May; 65(5-6):309-16. doi:
10.1515/znc-2010-5-601. [PMID: 20653231] - Vishnu Kumar, Pradyumn Singh, Ramesh Chander, Farzana Mahdi, Sushma Singh, Ranjana Singh, Ashok Kumar Khanna, Jitendra Kumar Saxena, Abbas Ali Mahdi, Vinod Kumar Singh. Hypolipidemic activity of Hibiscus rosa sinensis root in rats.
Indian journal of biochemistry & biophysics.
2009 Dec; 46(6):507-10. doi:
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The Journal of pharmacy and pharmacology.
2009 Dec; 61(12):1673-9. doi:
10.1211/jpp/61.12.0013. [PMID: 19958591] - Tariq Al-Qirim, Moyad Shahwan, Ghassan Shattat, Yusuf Al-Hiari, Ghassan Abu-Sheikha, Syed Zaidi. Pharmacological evaluation of novel indole-2-carboxamides as potent lipid-lowering agents in Triton-WR-1339-induced hyperlipidemic rats.
Zeitschrift fur Naturforschung. C, Journal of biosciences.
2009 Sep; 64(9-10):619-25. doi:
10.1515/znc-2009-9-1003. [PMID: 19957427] - Oliver Schieweck, Markus Damme, Bernd Schröder, Andrej Hasilik, Bernhard Schmidt, Torben Lübke. NCU-G1 is a highly glycosylated integral membrane protein of the lysosome.
The Biochemical journal.
2009 Jul; 422(1):83-90. doi:
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Eksperimental'naia i klinicheskaia farmakologiia.
2009 Jul; 72(4):25-7. doi:
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Pathobiology : journal of immunopathology, molecular and cellular biology.
2009; 76(6):315-21. doi:
10.1159/000245897. [PMID: 19955843] - Inhye Ham, Gabsik Yang, Jaejun Lee, Kyung-Jin Lee, Ho-Young Choi. Hypolipidemic effect of MeOH extract of Bambusae Caulis in Taeniam in hyperlipidemia induced by Triton WR-1339 and high cholesterol diet in rats.
Immunopharmacology and immunotoxicology.
2009; 31(3):439-45. doi:
10.1080/08923970902769638. [PMID: 19267283] - Julijana Kristl, Karmen Teskac, Miha Milek, Irena Mlinaric-Rascan. Surface active stabilizer tyloxapol in colloidal dispersions exerts cytostatic effects and apoptotic dismissal of cells.
Toxicology and applied pharmacology.
2008 Oct; 232(2):218-25. doi:
10.1016/j.taap.2008.06.019. [PMID: 18657561] - T A Korolenko, N G Savchenko, Ju V Yuz'ko, T V Alexeenko, N V Sorochinskaya. Activity of lysosomal enzymes in the bile and serum of mice with intrahepatic cholestasis.
Bulletin of experimental biology and medicine.
2008 May; 145(5):560-3. doi:
10.1007/s10517-008-0147-x. [PMID: 19145281] - Sung-Won Min, Dong-Hyun Kim. Kakkalide and irisolidone: HMG-CoA reductase inhibitors isolated from the flower of Pueraria thunbergiana.
Biological & pharmaceutical bulletin.
2007 Oct; 30(10):1965-8. doi:
10.1248/bpb.30.1965. [PMID: 17917273] - Jeong-Hyeon Ko, Sei-Jung Lee, Kye-Taek Lim. Hypolipidemic effect and antioxidant activity of glycoprotein isolated from Ulmus davidiana Nakai in Triton WR-1339-treated mouse.
Cell biochemistry and function.
2007 Sep; 25(5):495-500. doi:
10.1002/cbf.1337. [PMID: 16927415] - Hien-Trung Trinh, Sang-Jun Han, Sang-Wook Kim, Young Chul Lee, Dong-Hyun Kim. Bifidus fermentation increases hypolipidemic and hypoglycemic effects of red ginseng.
Journal of microbiology and biotechnology.
2007 Jul; 17(7):1127-33. doi:
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Bioorganic & medicinal chemistry.
2007 Jul; 15(13):4520-7. doi:
10.1016/j.bmc.2007.04.022. [PMID: 17485213] - Koichi Yasunaga, Shinichiro Saito, Yuan-Li Zhang, Antonio Hernandez-Ono, Henry N Ginsberg. Effects of triacylglycerol and diacylglycerol oils on blood clearance, tissue uptake, and hepatic apolipoprotein B secretion in mice.
Journal of lipid research.
2007 May; 48(5):1108-21. doi:
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American journal of physiology. Gastrointestinal and liver physiology.
2007 May; 292(5):G1439-49. doi:
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Journal of pharmacological and toxicological methods.
2007 Mar; 55(2):224-6. doi:
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