[1-heptadecanoyloxy-3-[hydroxy-(2,3,5,6-tetrahydroxy-4-phosphonooxycyclohexyl)oxyphosphoryl]oxypropan-2-yl] (5E,8E,11E,14E)-icosa-5,8,11,14-tetraenoate (BioDeep_00001023320)

   


代谢物信息卡片


[1-heptadecanoyloxy-3-[hydroxy-(2,3,5,6-tetrahydroxy-4-phosphonooxycyclohexyl)oxyphosphoryl]oxypropan-2-yl] (5E,8E,11E,14E)-icosa-5,8,11,14-tetraenoate

化学式: C46H82O16P2 (952.5078)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OC1C(C(C(C(C1O)O)OP(=O)(O)O)O)O)OC(=O)CCCC=CCC=CCC=CCC=CCCCCC
InChI: InChI=1S/C46H82O16P2/c1-3-5-7-9-11-13-15-17-19-20-21-23-25-27-29-31-33-35-40(48)60-38(36-58-39(47)34-32-30-28-26-24-22-18-16-14-12-10-8-6-4-2)37-59-64(56,57)62-46-43(51)41(49)45(42(50)44(46)52)61-63(53,54)55/h11,13,17,19,21,23,27,29,38,41-46,49-52H,3-10,12,14-16,18,20,22,24-26,28,30-37H2,1-2H3,(H,56,57)(H2,53,54,55)/b13-11+,19-17+,23-21+,29-27+



数据库引用编号

1 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Vedrana Marković, Yvon Jaillais. Phosphatidylinositol 4-phosphate: a key determinant of plasma membrane identity and function in plants. The New phytologist. 2022 08; 235(3):867-874. doi: 10.1111/nph.18258. [PMID: 35586972]
  • James B Konopka. Plasma Membrane Phosphatidylinositol 4-Phosphate Is Necessary for Virulence of Candida albicans. mBio. 2022 06; 13(3):e0036622. doi: 10.1128/mbio.00366-22. [PMID: 35467420]
  • Chen Braun, Xiaorong Xu Parks, Haani Qudsi, Coeli M B Lopes. Membrane pools of phosphatidylinositol-4-phosphate regulate KCNQ1/KCNE1 membrane expression. Communications biology. 2021 12; 4(1):1392. doi: 10.1038/s42003-021-02909-1. [PMID: 34907346]
  • Yongqing Yang, Xiuli Han, Liang Ma, Yujiao Wu, Xiao Liu, Haiqi Fu, Guoyong Liu, Xiaoguang Lei, Yan Guo. Dynamic changes of phosphatidylinositol and phosphatidylinositol 4-phosphate levels modulate H+-ATPase and Na+/H+ antiporter activities to maintain ion homeostasis in Arabidopsis under salt stress. Molecular plant. 2021 12; 14(12):2000-2014. doi: 10.1016/j.molp.2021.07.020. [PMID: 34339895]
  • Kay Oliver Schink, Kia Wee Tan, Hélène Spangenberg, Domenica Martorana, Marte Sneeggen, Virginie Stévenin, Jost Enninga, Coen Campsteijn, Camilla Raiborg, Harald Stenmark. The phosphoinositide coincidence detector Phafin2 promotes macropinocytosis by coordinating actin organisation at forming macropinosomes. Nature communications. 2021 11; 12(1):6577. doi: 10.1038/s41467-021-26775-x. [PMID: 34772942]
  • Hema Adhikari, Walaa E Kattan, Shivesh Kumar, Pei Zhou, John F Hancock, Christopher M Counter. Oncogenic KRAS is dependent upon an EFR3A-PI4KA signaling axis for potent tumorigenic activity. Nature communications. 2021 09; 12(1):5248. doi: 10.1038/s41467-021-25523-5. [PMID: 34504076]
  • Andrew King On Wong, Barry Paul Young, Christopher J R Loewen. Ist2 recruits the lipid transporters Osh6/7 to ER-PM contacts to maintain phospholipid metabolism. The Journal of cell biology. 2021 09; 220(9):. doi: 10.1083/jcb.201910161. [PMID: 34259806]
  • Noemi Ruiz-Lopez, Jessica Pérez-Sancho, Alicia Esteban Del Valle, Richard P Haslam, Steffen Vanneste, Rafael Catalá, Carlos Perea-Resa, Daniël Van Damme, Selene García-Hernández, Armando Albert, José Vallarino, Jinxing Lin, Jiří Friml, Alberto P Macho, Julio Salinas, Abel Rosado, Johnathan A Napier, Vitor Amorim-Silva, Miguel A Botella. Synaptotagmins at the endoplasmic reticulum-plasma membrane contact sites maintain diacylglycerol homeostasis during abiotic stress. The Plant cell. 2021 08; 33(7):2431-2453. doi: 10.1093/plcell/koab122. [PMID: 33944955]
  • Lizhen Song, Yanning Wang, Zhiai Guo, Sin M Lam, Guanghou Shui, Youfa Cheng. NCP2/RHD4/SAC7, SAC6 and SAC8 phosphoinositide phosphatases are required for PtdIns4P and PtdIns(4,5)P2 homeostasis and Arabidopsis development. The New phytologist. 2021 07; 231(2):713-725. doi: 10.1111/nph.17402. [PMID: 33876422]
  • Alex G Batrouni, Jeremy M Baskin. The chemistry and biology of phosphatidylinositol 4-phosphate at the plasma membrane. Bioorganic & medicinal chemistry. 2021 06; 40(?):116190. doi: 10.1016/j.bmc.2021.116190. [PMID: 33965837]
  • Mouhannad Malek, Anna M Wawrzyniak, Peter Koch, Christian Lüchtenborg, Manuel Hessenberger, Timo Sachsenheimer, Wonyul Jang, Britta Brügger, Volker Haucke. Inositol triphosphate-triggered calcium release blocks lipid exchange at endoplasmic reticulum-Golgi contact sites. Nature communications. 2021 05; 12(1):2673. doi: 10.1038/s41467-021-22882-x. [PMID: 33976123]
  • Ryo Kuroda, Mariko Kato, Tomohiko Tsuge, Takashi Aoyama. Arabidopsis phosphatidylinositol 4-phosphate 5-kinase genes PIP5K7, PIP5K8, and PIP5K9 are redundantly involved in root growth adaptation to osmotic stress. The Plant journal : for cell and molecular biology. 2021 05; 106(4):913-927. doi: 10.1111/tpj.15207. [PMID: 33606325]
  • Souade Ikhlef, Nicolas-Frédéric Lipp, Maud Magdeleine, Guillaume Drin. Fluorescence-Based Measurements of Phosphatidylserine/Phosphatidylinositol 4-Phosphate Exchange Between Membranes. Journal of visualized experiments : JoVE. 2021 03; ?(169):. doi: 10.3791/62177. [PMID: 33779604]
  • Jongyun Myeong, Cheon-Gyu Park, Byung-Chang Suh, Bertil Hille. Compartmentalization of phosphatidylinositol 4,5-bisphosphate metabolism into plasma membrane liquid-ordered/raft domains. Proceedings of the National Academy of Sciences of the United States of America. 2021 03; 118(9):. doi: 10.1073/pnas.2025343118. [PMID: 33619111]
  • A Sun, O Simsek Papur, E Dirkx, L Wong, T Sips, S Wang, A Strzelecka, M Nabben, J F C Glatz, D Neumann, J J F P Luiken. Phosphatidylinositol 4-kinase IIIβ mediates contraction-induced GLUT4 translocation and shows its anti-diabetic action in cardiomyocytes. Cellular and molecular life sciences : CMLS. 2021 Mar; 78(6):2839-2856. doi: 10.1007/s00018-020-03669-7. [PMID: 33090289]
  • Etienne Pays. The function of apolipoproteins L (APOLs): relevance for kidney disease, neurotransmission disorders, cancer and viral infection. The FEBS journal. 2021 01; 288(2):360-381. doi: 10.1111/febs.15444. [PMID: 32530132]
  • Rebecca Cabral-Dias, Yasmin Awadeh, Roberto J Botelho, Costin N Antonescu. Detection of Plasma Membrane Phosphoinositide Dynamics Using Genetically Encoded Fluorescent Protein Probes. Methods in molecular biology (Clifton, N.J.). 2021; 2251(?):73-89. doi: 10.1007/978-1-0716-1142-5_5. [PMID: 33481232]
  • Chloe E Snider, Alaina H Willet, HannahSofia T Brown, Jun-Song Chen, Joshua M Evers, Kathleen L Gould. Fission yeast Opy1 is an endogenous PI(4,5)P2 sensor that binds to the phosphatidylinositol 4-phosphate 5-kinase Its3. Journal of cell science. 2020 12; 133(23):. doi: 10.1242/jcs.247973. [PMID: 33172987]
  • Jian Li, David G Lambright, Victor W Hsu. Coordination of Grp1 recruitment mechanisms by its phosphorylation. Molecular biology of the cell. 2020 12; 31(25):2816-2825. doi: 10.1091/mbc.e20-03-0173. [PMID: 33026967]
  • Etienne Pays. The Mechanism of Kidney Disease Due to APOL1 Risk Variants. Journal of the American Society of Nephrology : JASN. 2020 11; 31(11):2502-2505. doi: 10.1681/asn.2020070954. [PMID: 32943491]
  • Wei Dong, Juan Lu, Xuejing Zhang, Yan Wu, Kaela Lettieri, Gerald R Hammond, Yang Hong. A polybasic domain in aPKC mediates Par6-dependent control of membrane targeting and kinase activity. The Journal of cell biology. 2020 07; 219(7):. doi: 10.1083/jcb.201903031. [PMID: 32580209]
  • Nigel W Griffiths, Lauren M Del Bel, Ronit Wilk, Julie A Brill. Cellular homeostasis in the Drosophila retina requires the lipid phosphatase Sac1. Molecular biology of the cell. 2020 05; 31(11):1183-1199. doi: 10.1091/mbc.e20-02-0161. [PMID: 32186963]
  • Sophie Uzureau, Laurence Lecordier, Pierrick Uzureau, Dorle Hennig, Jonas H Graversen, Fabrice Homblé, Pepe Ekulu Mfutu, Fanny Oliveira Arcolino, Ana Raquel Ramos, Rita M La Rovere, Tomas Luyten, Marjorie Vermeersch, Patricia Tebabi, Marc Dieu, Bart Cuypers, Stijn Deborggraeve, Marion Rabant, Christophe Legendre, Søren K Moestrup, Elena Levtchenko, Geert Bultynck, Christophe Erneux, David Pérez-Morga, Etienne Pays. APOL1 C-Terminal Variants May Trigger Kidney Disease through Interference with APOL3 Control of Actomyosin. Cell reports. 2020 03; 30(11):3821-3836.e13. doi: 10.1016/j.celrep.2020.02.064. [PMID: 32187552]
  • Gergő Gulyás, Mira Sohn, Yeun Ju Kim, Péter Várnai, Tamas Balla. ORP3 phosphorylation regulates phosphatidylinositol 4-phosphate and Ca2+ dynamics at plasma membrane-ER contact sites. Journal of cell science. 2020 03; 133(6):. doi: 10.1242/jcs.237388. [PMID: 32041906]
  • Deike J Omnus, Angela Cadou, Ffion B Thomas, Jakob M Bader, Nathaniel Soh, Gary H C Chung, Andrew N Vaughan, Christopher J Stefan. A heat-sensitive Osh protein controls PI4P polarity. BMC biology. 2020 03; 18(1):28. doi: 10.1186/s12915-020-0758-x. [PMID: 32169085]
  • James P Zewe, April M Miller, Sahana Sangappa, Rachel C Wills, Brady D Goulden, Gerald R V Hammond. Probing the subcellular distribution of phosphatidylinositol reveals a surprising lack at the plasma membrane. The Journal of cell biology. 2020 03; 219(3):. doi: 10.1083/jcb.201906127. [PMID: 32211893]
  • Chunguang Ren, Qianying Yuan, Xiaoying Jian, Paul A Randazzo, Wenwen Tang, Dianqing Wu. Small GTPase ARF6 Is a Coincidence-Detection Code for RPH3A Polarization in Neutrophil Polarization. Journal of immunology (Baltimore, Md. : 1950). 2020 02; 204(4):1012-1021. doi: 10.4049/jimmunol.1901080. [PMID: 31924649]
  • Mehdi Doumane, Marie-Cécile Caillaud. Assessing Extrinsic Membrane Protein Dependency to PI4P Using a Plasma Membrane to Endosome Relocalization Transient Assay in Nicotiana benthamiana. Methods in molecular biology (Clifton, N.J.). 2020; 2177(?):95-108. doi: 10.1007/978-1-0716-0767-1_9. [PMID: 32632808]
  • Nicolas-Frédéric Lipp, Romain Gautier, Maud Magdeleine, Maxime Renard, Véronique Albanèse, Alenka Čopič, Guillaume Drin. An electrostatic switching mechanism to control the lipid transfer activity of Osh6p. Nature communications. 2019 09; 10(1):3926. doi: 10.1038/s41467-019-11780-y. [PMID: 31477717]
  • Carlos Rubilar-Hernández, Claudio Osorio-Navarro, Francisca Cabello, Lorena Norambuena. PI4KIIIβ Activity Regulates Lateral Root Formation Driven by Endocytic Trafficking to the Vacuole. Plant physiology. 2019 09; 181(1):112-126. doi: 10.1104/pp.19.00695. [PMID: 31285293]
  • Taylor E Miller, Karen M Henkels, Mary Huddleston, Richard Salisbury, Saber M Hussain, Atsuo T Sasaki, Kwang-Jin Cho. Depletion of phosphatidylinositol 4-phosphate at the Golgi translocates K-Ras to mitochondria. Journal of cell science. 2019 08; 132(16):. doi: 10.1242/jcs.231886. [PMID: 31331963]
  • Chunguang Ren, Qianying Yuan, Martha Braun, Xia Zhang, Björn Petri, Jiasheng Zhang, Dongjoo Kim, Julia Guez-Haddad, Wenzhi Xue, Weijun Pan, Rong Fan, Paul Kubes, Zhaoxia Sun, Yarden Opatowsky, Franck Polleux, Erdem Karatekin, Wenwen Tang, Dianqing Wu. Leukocyte Cytoskeleton Polarization Is Initiated by Plasma Membrane Curvature from Cell Attachment. Developmental cell. 2019 04; 49(2):206-219.e7. doi: 10.1016/j.devcel.2019.02.023. [PMID: 30930167]
  • Danny Mollerup Sørensen, Henrik Waldal Holen, Jesper Torbøl Pedersen, Helle Juel Martens, Daniele Silvestro, Lyubomir Dimitrov Stanchev, Sara Rute Costa, Thomas Günther Pomorski, Rosa Laura López-Marqués, Michael Palmgren. The P5A ATPase Spf1p is stimulated by phosphatidylinositol 4-phosphate and influences cellular sterol homeostasis. Molecular biology of the cell. 2019 04; 30(9):1069-1084. doi: 10.1091/mbc.e18-06-0365. [PMID: 30785834]
  • Suthankamon Khrongyut, Atsara Rawangwong, Atthapon Pidsaya, Hiroyuki Sakagami, Hisatake Kondo, Wiphawi Hipkaeo. Localization of phosphatidylinositol 4-phosphate 5-kinase (PIP5K) α, β, γ in the three major salivary glands in situ of mice and their response to β-adrenoceptor stimulation. Journal of anatomy. 2019 04; 234(4):502-514. doi: 10.1111/joa.12944. [PMID: 30734271]
  • Sergio Botero, Rachel Chiaroni-Clarke, Sanford M Simon. Escherichia coli as a platform for the study of phosphoinositide biology. Science advances. 2019 03; 5(3):eaat4872. doi: 10.1126/sciadv.aat4872. [PMID: 30944849]
  • Ramya S Kuna, Seth J Field. GOLPH3: a Golgi phosphatidylinositol(4)phosphate effector that directs vesicle trafficking and drives cancer. Journal of lipid research. 2019 02; 60(2):269-275. doi: 10.1194/jlr.r088328. [PMID: 30266835]
  • Jung Mi Lim, Sujin Park, Mi-Sook Lee, Tamas Balla, Dongmin Kang, Sue Goo Rhee. Accumulation of PtdIns(4)P at the Golgi mediated by reversible oxidation of the PtdIns(4)P phosphatase Sac1 by H2O2. Free radical biology & medicine. 2019 01; 130(?):426-435. doi: 10.1016/j.freeradbiomed.2018.11.008. [PMID: 30448513]
  • Diego Sbrissa, Louie Semaan, Barani Govindarajan, Yanfeng Li, Nicholas J Caruthers, Paul M Stemmer, Michael L Cher, Seema Sethi, Ulka Vaishampayan, Assia Shisheva, Sreenivasa R Chinni. A novel cross-talk between CXCR4 and PI4KIIIα in prostate cancer cells. Oncogene. 2019 01; 38(3):332-344. doi: 10.1038/s41388-018-0448-0. [PMID: 30111818]
  • Mira Sohn, Daniel J Toth, Tamas Balla. Monitoring Non-vesicular Transport of Phosphatidylserine and Phosphatidylinositol 4-Phosphate in Intact Cells by BRET Analysis. Methods in molecular biology (Clifton, N.J.). 2019; 1949(?):13-22. doi: 10.1007/978-1-4939-9136-5_2. [PMID: 30790245]
  • Shinya Mochizuki, Harukata Miki, Ruyun Zhou, Yukiharu Kido, Wataru Nishimura, Motoshi Kikuchi, Yasuko Noda. Oxysterol-binding protein-related protein (ORP) 6 localizes to the ER and ER-plasma membrane contact sites and is involved in the turnover of PI4P in cerebellar granule neurons. Experimental cell research. 2018 09; 370(2):601-612. doi: 10.1016/j.yexcr.2018.07.025. [PMID: 30028970]
  • Rafael Gil de Rubio, Richard F Ransom, Sundeep Malik, David I Yule, Arun Anantharam, Alan V Smrcka. Phosphatidylinositol 4-phosphate is a major source of GPCR-stimulated phosphoinositide production. Science signaling. 2018 09; 11(547):. doi: 10.1126/scisignal.aan1210. [PMID: 30206135]
  • Sruthi S Balakrishnan, Urbashi Basu, Dhananjay Shinde, Rajan Thakur, Manish Jaiswal, Padinjat Raghu. Regulation of PI4P levels by PI4KIIIα during G-protein-coupled PLC signaling in Drosophila photoreceptors. Journal of cell science. 2018 08; 131(15):. doi: 10.1242/jcs.217257. [PMID: 29980590]
  • Antonietta Pietrangelo, Neale D Ridgway. Golgi localization of oxysterol binding protein-related protein 4L (ORP4L) is regulated by ligand binding. Journal of cell science. 2018 07; 131(14):. doi: 10.1242/jcs.215335. [PMID: 29930082]
  • Alejandro Alvarez-Prats, Ivana Bjelobaba, Zane Aldworth, Takashi Baba, Daniel Abebe, Yeun Ju Kim, Stanko S Stojilkovic, Mark Stopfer, Tamas Balla. Schwann-Cell-Specific Deletion of Phosphatidylinositol 4-Kinase Alpha Causes Aberrant Myelination. Cell reports. 2018 06; 23(10):2881-2890. doi: 10.1016/j.celrep.2018.05.019. [PMID: 29874576]
  • Matthieu Pierre Platre, Lise C Noack, Mehdi Doumane, Vincent Bayle, Mathilde Laetitia Audrey Simon, Lilly Maneta-Peyret, Laetitia Fouillen, Thomas Stanislas, Laia Armengot, Přemysl Pejchar, Marie-Cécile Caillaud, Martin Potocký, Alenka Čopič, Patrick Moreau, Yvon Jaillais. A Combinatorial Lipid Code Shapes the Electrostatic Landscape of Plant Endomembranes. Developmental cell. 2018 05; 45(4):465-480.e11. doi: 10.1016/j.devcel.2018.04.011. [PMID: 29754803]
  • Mira Sohn, Marek Korzeniowski, James P Zewe, Rachel C Wills, Gerald R V Hammond, Jana Humpolickova, Lukas Vrzal, Dominika Chalupska, Vaclav Veverka, Gregory D Fairn, Evzen Boura, Tamas Balla. PI(4,5)P2 controls plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER-PM contact sites. The Journal of cell biology. 2018 05; 217(5):1797-1813. doi: 10.1083/jcb.201710095. [PMID: 29472386]
  • Kan-Na Tomioku, Mikiko Shigekuni, Hiroki Hayashi, Akane Yoshida, Taiki Futagami, Hisanori Tamaki, Kenji Tanabe, Akikazu Fujita. Nanoscale domain formation of phosphatidylinositol 4-phosphate in the plasma and vacuolar membranes of living yeast cells. European journal of cell biology. 2018 May; 97(4):269-278. doi: 10.1016/j.ejcb.2018.03.007. [PMID: 29609807]
  • Cheol-Min Yoo, Satoshi Naramoto, J Alan Sparks, Bibi Rafeiza Khan, Jin Nakashima, Hiroo Fukuda, Elison B Blancaflor. Deletion analysis of AGD1 reveals domains crucial for plasma membrane recruitment and function in root hair polarity. Journal of cell science. 2018 01; 131(2):. doi: 10.1242/jcs.203828. [PMID: 28646092]
  • Wataru Yamamoto, Suguru Wada, Makoto Nagano, Kaito Aoshima, Daria Elisabeth Siekhaus, Junko Y Toshima, Jiro Toshima. Distinct roles for plasma membrane PtdIns(4)P and PtdIns(4,5)P2 during receptor-mediated endocytosis in yeast. Journal of cell science. 2018 01; 131(1):. doi: 10.1242/jcs.207696. [PMID: 29192062]
  • Yasuhiro Moriwaki, Yuho Ohno, Tomohiro Ishii, Yuki Takamura, Yuko Kita, Kazuhiko Watabe, Kazunori Sango, Shoutaro Tsuji, Hidemi Misawa. SIMPLE binds specifically to PI4P through SIMPLE-like domain and participates in protein trafficking in the trans-Golgi network and/or recycling endosomes. PloS one. 2018; 13(6):e0199829. doi: 10.1371/journal.pone.0199829. [PMID: 29953492]
  • Kangmin He, Robert Marsland, Srigokul Upadhyayula, Eli Song, Song Dang, Benjamin R Capraro, Weiming Wang, Wesley Skillern, Raphael Gaudin, Minghe Ma, Tom Kirchhausen. Dynamics of phosphoinositide conversion in clathrin-mediated endocytic traffic. Nature. 2017 12; 552(7685):410-414. doi: 10.1038/nature25146. [PMID: 29236694]
  • Luzia S Sampaio, Paulo A da Silva, Valdilene S Ribeiro, Carmem Castro-Chaves, Lucienne S Lara, Adalberto Vieyra, M Einicker-Lamas. Bioactive lipids are altered in the kidney of chronic undernourished rats: is there any correlation with the progression of prevalent nephropathies?. Lipids in health and disease. 2017 Dec; 16(1):245. doi: 10.1186/s12944-017-0634-z. [PMID: 29246161]
  • Gergő Gulyás, Glória Radvánszki, Rita Matuska, András Balla, László Hunyady, Tamas Balla, Péter Várnai. Plasma membrane phosphatidylinositol 4-phosphate and 4,5-bisphosphate determine the distribution and function of K-Ras4B but not H-Ras proteins. The Journal of biological chemistry. 2017 11; 292(46):18862-18877. doi: 10.1074/jbc.m117.806679. [PMID: 28939768]
  • Rajesh Ghai, Ximing Du, Huan Wang, Jiangqing Dong, Charles Ferguson, Andrew J Brown, Robert G Parton, Jia-Wei Wu, Hongyuan Yang. ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P 2) and regulate its level at the plasma membrane. Nature communications. 2017 10; 8(1):757. doi: 10.1038/s41467-017-00861-5. [PMID: 28970484]
  • Akane Yoshida, Hiroki Hayashi, Kenji Tanabe, Akikazu Fujita. Segregation of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate into distinct microdomains on the endosome membrane. Biochimica et biophysica acta. Biomembranes. 2017 Oct; 1859(10):1880-1890. doi: 10.1016/j.bbamem.2017.06.014. [PMID: 28648675]
  • Takashi Hirama, Raibatak Das, Yanbo Yang, Charles Ferguson, Amy Won, Christopher M Yip, Jason G Kay, Sergio Grinstein, Robert G Parton, Gregory D Fairn. Phosphatidylserine dictates the assembly and dynamics of caveolae in the plasma membrane. The Journal of biological chemistry. 2017 08; 292(34):14292-14307. doi: 10.1074/jbc.m117.791400. [PMID: 28698382]
  • Sufyan G Sayyed, François Jouret, Marjorie Vermeersch, David Pérez-Morga, Stéphane Schurmans. The lipid 5-phoshatase SHIP2 controls renal brush border ultrastructure and function by regulating the activation of ERM proteins. Kidney international. 2017 07; 92(1):125-139. doi: 10.1016/j.kint.2017.01.008. [PMID: 28302370]
  • Li Li, Fawei Wang, Peiwen Yan, Wen Jing, Chunxia Zhang, Jörg Kudla, Wenhua Zhang. A phosphoinositide-specific phospholipase C pathway elicits stress-induced Ca2+ signals and confers salt tolerance to rice. The New phytologist. 2017 May; 214(3):1172-1187. doi: 10.1111/nph.14426. [PMID: 28157263]
  • Samual C Allgood, Barbara P Romero Dueñas, Rebecca R Noll, Colleen Pike, Sean Lein, M Ramona Neunuebel. Legionella Effector AnkX Disrupts Host Cell Endocytic Recycling in a Phosphocholination-Dependent Manner. Frontiers in cellular and infection microbiology. 2017; 7(?):397. doi: 10.3389/fcimb.2017.00397. [PMID: 28944216]
  • Ganiyu Olabanji Alli-Balogun, Christina A Gewinner, Ruth Jacobs, Janos Kriston-Vizi, Mark G Waugh, Shane Minogue. Phosphatidylinositol 4-kinase IIβ negatively regulates invadopodia formation and suppresses an invasive cellular phenotype. Molecular biology of the cell. 2016 12; 27(25):4033-4042. doi: 10.1091/mbc.e16-08-0564. [PMID: 27798239]
  • Mengke Xing, Marshall C Peterman, Robert L Davis, Karen Oegema, Andrew K Shiau, Seth J Field. GOLPH3 drives cell migration by promoting Golgi reorientation and directional trafficking to the leading edge. Molecular biology of the cell. 2016 12; 27(24):3828-3840. doi: 10.1091/mbc.e16-01-0005. [PMID: 27708138]
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