(4E,8E,10E,12E,16E,19E)-7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid (BioDeep_00001022024)
代谢物信息卡片
(4E,8E,10E,12E,16E,19E)-7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid
化学式: C22H32O4 (360.2300472)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCC=CCC=CCC(C=CC=CC=CC(CC=CCCC(=O)O)O)O
InChI: InChI=1S/C22H32O4/c1-2-3-4-5-6-10-15-20(23)16-11-7-8-12-17-21(24)18-13-9-14-19-22(25)26/h3-4,6-13,16-17,20-21,23-24H,2,5,14-15,18-19H2,1H3,(H,25,26)/b4-3+,8-7+,10-6+,13-9+,16-11+,17-12+
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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BioCyc(0)
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Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Inês Ferreira, Filipa Falcato, Narcisa Bandarra, Amélia P Rauter. Resolvins, Protectins, and Maresins: DHA-Derived Specialized Pro-Resolving Mediators, Biosynthetic Pathways, Synthetic Approaches, and Their Role in Inflammation.
Molecules (Basel, Switzerland).
2022 Mar; 27(5):. doi:
10.3390/molecules27051677. [PMID: 35268778] - Ellen C Keeley, Han J Li, Christopher R Cogle, Eileen M Handberg, C Noel Bairey Merz, Carl J Pepine. Specialized Proresolving Mediators in Symptomatic Women With Coronary Microvascular Dysfunction (from the Women's Ischemia Trial to Reduce Events in Nonobstructive CAD [WARRIOR] Trial).
The American journal of cardiology.
2022 01; 162(?):1-5. doi:
10.1016/j.amjcard.2021.09.015. [PMID: 34728061] - Xinyue Li, Butuo Xu, Jing Wu, Yueli Pu, Shengrong Wan, Yan Zeng, Mei Wang, Lifang Luo, Fanjie Zhang, Zongzhe Jiang, Yong Xu. Maresin 1 Alleviates Diabetic Kidney Disease via LGR6-Mediated cAMP-SOD2-ROS Pathway.
Oxidative medicine and cellular longevity.
2022; 2022(?):7177889. doi:
10.1155/2022/7177889. [PMID: 35498124] - María José Rodríguez, Matías Sabaj, Gerardo Tolosa, Francisca Herrera Vielma, María José Zúñiga, Daniel R González, Jessica Zúñiga-Hernández. Maresin-1 Prevents Liver Fibrosis by Targeting Nrf2 and NF-κB, Reducing Oxidative Stress and Inflammation.
Cells.
2021 12; 10(12):. doi:
10.3390/cells10123406. [PMID: 34943914] - Xia Fang, Hongya Wang, Ting Ye, Xiaolan Fu, Xiaozhen Tan, Yan Zeng, Jiahao Fan, Yong Xu. Low serum Maresin-1 levels are associated with non-alcoholic fatty liver disease: a cross-sectional study.
Lipids in health and disease.
2021 Aug; 20(1):96. doi:
10.1186/s12944-021-01518-5. [PMID: 34461919] - Dan Li, Menglong Wang, Jing Ye, Jishou Zhang, Yao Xu, Zhen Wang, Mengmeng Zhao, Di Ye, Jun Wan. Maresin 1 alleviates the inflammatory response, reduces oxidative stress and protects against cardiac injury in LPS-induced mice.
Life sciences.
2021 Jul; 277(?):119467. doi:
10.1016/j.lfs.2021.119467. [PMID: 33811894] - Issa Beegun, Duco S Koenis, Ghassan Alusi, Jesmond Dalli. Dysregulated Maresin Concentrations in Plasma and Nasal Secretions From Patients With Chronic Rhinosinusitis.
Frontiers in immunology.
2021; 12(?):733019. doi:
10.3389/fimmu.2021.733019. [PMID: 34531873] - Guochun Ou, Qin Liu, Chengxiu Yu, Xiaoju Chen, Wenbo Zhang, Yong Chen, Tao Wang, Yongqiang Luo, Guolu Jiang, Mingmei Zhu, Hongmei Li, Mei Zeng. The Protective Effects of Maresin 1 in the OVA-Induced Asthma Mouse Model.
Mediators of inflammation.
2021; 2021(?):4131420. doi:
10.1155/2021/4131420. [PMID: 33628113] - Yingying Lu, Guotao Lu, Lin Gao, Qingtian Zhu, Jing Xue, Jingzhu Zhang, Xiaojie Ma, Nan Ma, Qi Yang, Jie Dong, Weijuan Gong, Weiqin Li, Zhihui Tong. The Proresolving Lipid Mediator Maresin1 Alleviates Experimental Pancreatitis via Switching Macrophage Polarization.
Mediators of inflammation.
2021; 2021(?):6680456. doi:
10.1155/2021/6680456. [PMID: 33776575] - Hui Li, Yu Hao, Li-Li Yang, Xin-Yang Wang, Xin-Yu Li, Suwas Bhandari, Jun Han, Yong-Jian Liu, Yu-Qiang Gong, Aaron Scott, Fang Gao Smith, Sheng-Wei Jin. MCTR1 alleviates lipopolysaccharide-induced acute lung injury by protecting lung endothelial glycocalyx.
Journal of cellular physiology.
2020 10; 235(10):7283-7294. doi:
10.1002/jcp.29628. [PMID: 32037554] - Sisi Zheng, Minqi Ma, Zhongwang Li, Yu Hao, Hui Li, Panhan Fu, Shengwei Jin. Posttreatment of Maresin1 Inhibits NLRP3 inflammasome activation via promotion of NLRP3 ubiquitination.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2020 09; 34(9):11944-11956. doi:
10.1096/fj.202000665rr. [PMID: 32667092] - Huayi Ma, Song Mo, Qushen Yi, Junhua Lai, Huan Liu, Zhanying Shi. Role and Mechanism of Maresin-1 in Acute Lung Injury Induced by Trauma-Hemorrhagic Shock.
Medical science monitor : international medical journal of experimental and clinical research.
2020 Aug; 26(?):e923518. doi:
10.12659/msm.923518. [PMID: 32750045] - Dominika Maciejewska, Arleta Drozd, Karolina Skonieczna-Żydecka, Marta Skórka-Majewicz, Karolina Dec, Karolina Jakubczyk, Anna Pilutin, Ewa Stachowska. Eicosanoids in Nonalcoholic Fatty Liver Disease (NAFLD) Progression. Do Serum Eicosanoids Profile Correspond with Liver Eicosanoids Content during NAFLD Development and Progression?.
Molecules (Basel, Switzerland).
2020 Apr; 25(9):. doi:
10.3390/molecules25092026. [PMID: 32349225] - Dong-Soon Im. Maresin-1 resolution with RORα and LGR6.
Progress in lipid research.
2020 04; 78(?):101034. doi:
10.1016/j.plipres.2020.101034. [PMID: 32360520] - Luiza Oliveira Perucci, Talita Adriana Pereira Santos, Patrícia Campi Santos, Lívia Cristina Ribeiro Teixeira, Patrícia Nessralla Alpoim, Karina Braga Gomes, Lirlândia Pires Sousa, Luci Maria Sant'Ana Dusse, André Talvani. Pre-eclampsia is associated with reduced resolvin D1 and maresin 1 to leukotriene B4 ratios in the plasma.
American journal of reproductive immunology (New York, N.Y. : 1989).
2020 02; 83(2):e13206. doi:
10.1111/aji.13206. [PMID: 31679164] - Tian Miao, Bangliang Huang, Niexia He, Lihua Sun, Guangsheng Du, Xiaoli Gong, Yong Xu, Yi Zheng, Hongting Zheng, Hua Qu. Decreased Plasma Maresin 1 Concentration Is Associated with Diabetic Foot Ulcer.
Mediators of inflammation.
2020; 2020(?):4539035. doi:
10.1155/2020/4539035. [PMID: 32377160] - Chengjie Lv, Qi Jin. Maresin-1 Inhibits Oxidative Stress and Inflammation and Promotes Apoptosis in a Mouse Model of Caerulein-Induced Acute Pancreatitis.
Medical science monitor : international medical journal of experimental and clinical research.
2019 10; 25(?):8181-8189. doi:
10.12659/msm.917380. [PMID: 31671079] - Fahad Munir, Muhammad Babar Jamshed, Numan Shahid, Syed Aun Muhammad, Adheesh Bhandari, QiYu Zhang. Protective effects of maresin 1 against inflammation in experimentally induced acute pancreatitis and related lung injury.
American journal of physiology. Gastrointestinal and liver physiology.
2019 09; 317(3):G333-G341. doi:
10.1152/ajpgi.00078.2019. [PMID: 31125268] - Yun Qiu, Yichen Wu, Hongmei Zhao, Hong Sun, Sumin Gao. Maresin 1 mitigates renal ischemia/reperfusion injury in mice via inhibition of the TLR4/MAPK/NF-κB pathways and activation of the Nrf2 pathway.
Drug design, development and therapy.
2019; 13(?):739-745. doi:
10.2147/dddt.s188654. [PMID: 30863013] - Kazuki Ohuchi, Yoko Ono, Mina Joho, Kazuhiro Tsuruma, Shiho Ogami, Shinsaku Yamane, Michinori Funato, Hideo Kaneko, Shinsuke Nakamura, Hideaki Hara, Masamitsu Shimazawa. A Docosahexaenoic Acid-Derived Pro-resolving Agent, Maresin 1, Protects Motor Neuron Cells Death.
Neurochemical research.
2018 Jul; 43(7):1413-1423. doi:
10.1007/s11064-018-2556-1. [PMID: 29797139] - Anne Barden, Sujata Shinde, Michael Phillips, Lawrence Beilin, Emilie Mas, Jonathan M Hodgson, Ian Puddey, Trevor A Mori. The effects of alcohol on plasma lipid mediators of inflammation resolution in patients with Type 2 diabetes mellitus.
Prostaglandins, leukotrienes, and essential fatty acids.
2018 06; 133(?):29-34. doi:
10.1016/j.plefa.2018.04.004. [PMID: 29789130] - Jun-Li Zhang, Xiao-Jun Zhuo, Jing Lin, Ling-Chun Luo, Wei-Yang Ying, Xiang Xie, Hua-Wei Zhang, Jing-Xiang Yang, Dan Li, Fang Gao Smith, Sheng-Wei Jin. Maresin1 stimulates alveolar fluid clearance through the alveolar epithelial sodium channel Na,K-ATPase via the ALX/PI3K/Nedd4-2 pathway.
Laboratory investigation; a journal of technical methods and pathology.
2017 05; 97(5):543-554. doi:
10.1038/labinvest.2016.150. [PMID: 28218740] - Jesmond Dalli, Iliyan Vlasakov, Ian R Riley, Ana R Rodriguez, Bernd W Spur, Nicos A Petasis, Nan Chiang, Charles N Serhan. Maresin conjugates in tissue regeneration biosynthesis enzymes in human macrophages.
Proceedings of the National Academy of Sciences of the United States of America.
2016 10; 113(43):12232-12237. doi:
10.1073/pnas.1607003113. [PMID: 27791009] - Ruidong Li, Yaxin Wang, Zhijun Ma, Muyuan Ma, Di Wang, Gengchen Xie, Yuping Yin, Peng Zhang, Kaixiong Tao. Maresin 1 Mitigates Inflammatory Response and Protects Mice from Sepsis.
Mediators of inflammation.
2016; 2016(?):3798465. doi:
10.1155/2016/3798465. [PMID: 28042205]