(23E,25E,27E,29E,31E,33E,35Z)-22-(4-amino-3,5-dihydroxy-6-methyloxan-2-yl)oxy-38-[7-(4-aminophenyl)-5-hydroxy-4-methyl-7-oxoheptan-2-yl]-10,12,14,18,20-pentahydroxy-37-methyl-2,4,8,16-tetraoxo-1-oxacyclooctatriaconta-23,25,27,29,31,33,35-heptaene-19-carboxylic acid (BioDeep_00001006069)

   


代谢物信息卡片


(23E,25E,27E,29E,31E,33E,35Z)-22-(4-amino-3,5-dihydroxy-6-methyloxan-2-yl)oxy-38-[7-(4-aminophenyl)-5-hydroxy-4-methyl-7-oxoheptan-2-yl]-10,12,14,18,20-pentahydroxy-37-methyl-2,4,8,16-tetraoxo-1-oxacyclooctatriaconta-23,25,27,29,31,33,35-heptaene-19-carboxylic acid

化学式: C59H84N2O18 (1108.5718844)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1C=CC=CC=CC=CC=CC=CC=CC(CC(C(C(CC(=O)CC(CC(CC(CC(=O)CCCC(=O)CC(=O)OC1C(C)CC(C)C(CC(=O)C2=CC=C(C=C2)N)O)O)O)O)O)C(=O)O)O)OC3C(C(C(C(O3)C)O)N)O
InChI: InChI=1S/C59H84N2O18/c1-35-18-15-13-11-9-7-5-6-8-10-12-14-16-21-47(78-59-56(74)54(61)55(73)38(4)77-59)33-51(71)53(58(75)76)50(70)31-46(67)30-45(66)29-44(65)28-43(64)27-41(62)19-17-20-42(63)32-52(72)79-57(35)37(3)26-36(2)48(68)34-49(69)39-22-24-40(60)25-23-39/h5-16,18,21-25,35-38,43-45,47-48,50-51,53-57,59,64-66,68,70-71,73-74H,17,19-20,26-34,60-61H2,1-4H3,(H,75,76)/b6-5+,9-7+,10-8+,13-11+,14-12+,18-15-,21-16+

描述信息

同义名列表

1 个代谢物同义名

(23E,25E,27E,29E,31E,33E,35Z)-22-(4-amino-3,5-dihydroxy-6-methyloxan-2-yl)oxy-38-[7-(4-aminophenyl)-5-hydroxy-4-methyl-7-oxoheptan-2-yl]-10,12,14,18,20-pentahydroxy-37-methyl-2,4,8,16-tetraoxo-1-oxacyclooctatriaconta-23,25,27,29,31,33,35-heptaene-19-carboxylic acid



数据库引用编号

1 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • O Raatikainen, R A Kauppinen, H Komulainen, H Taipale, T Pirttilä, J Tuomisto. Polyene antibiotics increase the ionic permeability of synaptosomal plasma membranes. Biochemical pharmacology. 1991 May; 41(9):1345-50. doi: 10.1016/0006-2952(91)90107-g. [PMID: 2018566]
  • G León, W Mosca, A Arguello. [In vitro evaluation of the trypanocidal activity of 3 antimycotic agents on fresh plasma infected with T. cruzi]. Acta cientifica venezolana. 1988; 39(4):344-8. doi: NULL. [PMID: 3152042]
  • B E Cohen, H Ramos, M Gamargo, J Urbina. The water and ionic permeability induced by polyene antibiotics across plasma membrane vesicles from Leishmania sp. Biochimica et biophysica acta. 1986 Aug; 860(1):57-65. doi: 10.1016/0005-2736(86)90498-0. [PMID: 3730386]
  • A M Efendiev, V D Pomoĭnetskiĭ, L D Smirnov, A A Kubatiev. [Effect of antioxidants on the synthesis of prostaglandins, prostacyclin and thromboxane in different layers of the kidneys of old rats]. Farmakologiia i toksikologiia. 1986 May; 49(3):60-3. doi: NULL. [PMID: 3522269]
  • A M Efendiev, V D Pomoĭnetskiĭ, A A Kubatiev. [Effect of polyene antibiotics on the enzyme activity of prostaglandin metabolism in different layers of the kidneys of old rats]. Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology. 1986 Apr; 31(4):284-8. doi: NULL. [PMID: 3717926]
  • J Brajtburg, S Elberg, G S Kobayashi, G Medoff. Effects of serum lipoproteins on damage to erythrocytes and Candida albicans cells by polyene antibiotics. The Journal of infectious diseases. 1986 Mar; 153(3):623-6. doi: 10.1093/infdis/153.3.623. [PMID: 3512734]
  • G K Paliĭ, S A Ivanova. [Sensitivity of fungi in the genus Candida to antimicrobial preparations]. Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology. 1986 Mar; 31(3):218-20. doi: NULL. [PMID: 2940962]
  • A M Efendiev, V D Pomoĭnetskiĭ, A A Kubatiev. [Prostaglandin synthetase activity in the different layers of the kidneys of young rats exposed to polyene antibiotics]. Biulleten' eksperimental'noi biologii i meditsiny. 1986 Mar; 101(3):302-4. doi: NULL. [PMID: 3082383]
  • P O Madsen, T Dørflinger, P C Frimodt-Møller, K M Jensen. Candicidin in treatment of benign prostatic hypertrophy. The Journal of urology. 1984 Dec; 132(6):1235-8. doi: 10.1016/s0022-5347(17)50112-3. [PMID: 6209428]
  • K M Jensen, P O Madsen. Candicidin treatment of prostatism: a prospective double-blind placebo-controlled study. Urological research. 1983; 11(1):7-10. doi: 10.1007/bf00272701. [PMID: 6190290]
  • C P Schaffner, D R Brill, A K Singhal, D P Bonner, N I Goldstein, G M Wang. Absence of cholesterogenesis regulation in the liver and prostate of the BIO 87.20 hamster. Lipids. 1981 Nov; 16(11):835-40. doi: 10.1007/bf02535039. [PMID: 7311743]
  • A Ia Oksman, M A Shneĭder, A A Eremeeva, N P Karel'skaia, I M Tereshin. [Changes in the state of plasma membrane proteins of tumor cells exposed to a polyene antibiotic and cyclophosphamide]. Antibiotiki. 1981 Sep; 26(9):692-4. doi: NULL. [PMID: 7294761]
  • A K Singhal, E H Mosbach, C P Schaffner. Effect of candicidin on cholesterol and bile acid metabolism in the rat. Lipids. 1981 Jun; 16(6):423-6. doi: 10.1007/bf02535009. [PMID: 7266266]
  • M A Mikhaĭlova, A M Virina, T I Kravchenko. [Characteristics of a strain of C. albicans resistant to polyene antibiotics]. Antibiotiki. 1979 Nov; 24(11):828-31. doi: NULL. [PMID: 389154]
  • N A Peshkova. [Pharmacological properties of water-soluble levorin]. Antibiotiki. 1978 Oct; 23(10):906-10. doi: NULL. [PMID: 708000]
  • L S Kravchenko, L A Nesterova, O I Glubokovskaia, I M Tereshin. [Effect of levorin on the rat liver plasma membranes in experimental fatty dystrophy]. Antibiotiki. 1978 Sep; 23(9):823-9. doi: NULL. [PMID: 697340]
  • W C Hausheer, H Fisher. The antihypercholesterolemic properties of N,N'-diacetyl and methyl ester derivatives of candicidin in cockerels. The Journal of nutrition. 1978 Jul; 108(7):1054-60. doi: 10.1093/jn/108.7.1054. [PMID: 660298]
  • W C Hausheer, H Fisher. The antihypercholesterolemic activity of candicdin as a function of dietary cholesterol in cockerels. The Journal of nutrition. 1978 Apr; 108(4):712-8. doi: 10.1093/jn/108.4.712. [PMID: 632955]
  • N D Nigro, R L Campbell, J S Gantt, Y N Lin, D V Singh. A comparison of the effects of the hypocholesteremic agents, cholestyramine and candicidin, on the induction of intestinal tumors in rats by azoxymethane. Cancer research. 1977 Sep; 37(9):3198-203. doi: NULL. [PMID: 328141]
  • G M Wang, C P Schaffner. Effect of candicidin and colestipol on the testes and prostate glands of BIO 87.20 hamsters. Investigative urology. 1976 Jul; 14(1):66-71. doi: NULL. [PMID: 60302]
  • J English, J Chakraborty, V Marks. The effect of some polyene macrolides on absorption from the small intestine in the rat. The Journal of pharmacy and pharmacology. 1976 Jan; 28(1):49-52. doi: 10.1111/j.2042-7158.1976.tb04022.x. [PMID: 6650]
  • H Gershon, L Shanks. Fungitoxicity of 1,4-naphthoquinones to Candida albicans and Trichophyton mentagrophytes. Canadian journal of microbiology. 1975 Sep; 21(9):1317-21. doi: 10.1139/m75-198. [PMID: 241479]
  • A Sporer, S Cohen, M H Kamat, J J Seebode. Candicidin: physiologic effect on prostate. Urology. 1975 Sep; 6(3):298-304. doi: 10.1016/0090-4295(75)90750-5. [PMID: 51533]
  • L A Orkin. Efficacy of candicidin in benign prostatic hypertrophy. Urology. 1974 Jul; 4(1):80-4. doi: 10.1016/0090-4295(74)90113-7. [PMID: 21322990]